Research Topics
Species | Takeshi IshiiSummaryAffiliation: University of Shizuoka Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Binding affinity of tea catechins for HSA: characterization by high-performance affinity chromatography with immobilized albumin columnTakeshi Ishii
Department of Food and Nutritional Sciences, and Global COE Program, University of Shizuoka, 52 1 Yada, Suruga ku Shizuoka, Japan
Mol Nutr Food Res 54:816-22. 2010..Our findings provide fundamental information on the relationship between the chemical structure of tea catechins and its biological activity...
A new method for the detection and characterization of alpha-lipoic acid mixed disulphidesTakeshi Ishii
Department of Food and Nutritional Sciences, and Global COE Program, University of Shizuoka, 52 1 Yada, Suruga ku Shizuoka 422 8526, Japan
Free Radic Res 44:403-9. 2010..These results may provide further biological evidence that LA is a potential modifier of intracellular sulphydryls through mixed disulfide formation...
Characterization of acrolein-induced protein cross-linksTakeshi Ishii
Department of Food and Nutritional Sciences, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Free Radic Res 41:1253-60. 2007..In conclusion, the use of mass spectrometric techniques provided chemical evidence for protein cross-linking with ACR...
Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modificationsTakeshi Ishii
Department of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan
Biosci Biotechnol Biochem 74:663-6. 2010..PQQ may contribute to the regulation of intracellular protein functions through its prooxidant action...
Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albuminTakeshi Ishii
Department of Food and Nutritional Sciences, and Global Center of Excellence COE Program, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Bioorg Med Chem 18:4892-6. 2010....
Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilizationTakeshi Ishii
Department of Food and Nutritional Sciences, and Global Center of Excellence Program, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Biosci Biotechnol Biochem 75:100-6. 2011....
Influence of the galloyl moiety in tea catechins on binding affinity for human serum albuminKanako Minoda
Department of Food and Nutritional Sciences, and Global COE Program, University of Shizuoka, Japan
J Nutr Sci Vitaminol (Tokyo) 56:331-4. 2010..These observations indicate that catechins with a galloyl moiety have higher binding affinities toward HSA than catechins lacking a galloyl moiety...
Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidationTakeshi Ishii
Department of Food and Nutritional Sciences and Global COE Program, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Free Radic Biol Med 45:1384-94. 2008..Based on these findings, we propose that the covalent modification of proteins by EGCG may be a novel pathway related to the biological activity of EGCG...
Covalent binding of tea catechins to protein thiols: the relationship between stability and electrophilic reactivityTaiki Mori
Department of Food and Nutritional Sciences, and Global Center of Excellence Program, University of Shizuoka, Shizuoka, Japan
Biosci Biotechnol Biochem 74:2451-6. 2010..Consequently, the difference in these properties of tea catechins can contribute to the magnitude of their biological activities...
Albumin stabilizes (-)-epigallocatechin gallate in human serum: binding capacity and antioxidant propertyMin Jung Bae
Department of Food and Nutritional Sciences, and Global COE Program, University of Shizuoka, Shizuoka, Japan
Mol Nutr Food Res 53:709-15. 2009..Incubation of EGCg with HSA is accompanied by the oxidation of a free sulfhydryl group in HSA. These results suggest that the antioxidant property and the binding capacity of HSA contribute to the stabilization of EGCg in human serum...
Site-specific modification of positively-charged surfaces on human serum albumin by malondialdehydeTakeshi Ishii
Department of Food and Nutritional Sciences, and Global COE Program, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Biochem Biophys Res Commun 371:28-32. 2008..The results of this study indicate that the modification of proteins by lipid-derived aldehydes may be influenced by the electrostatic potential of the protein surface...
Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopyYoshinori Uekusa
Department of Food and Nutritional Sciences and Global COE Program, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Biochim Biophys Acta 1808:1654-60. 2011....
Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane columnYoshinori Uekusa
Laboratory of Molecular Food Engineering and Global COE Program, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan
Biosci Biotechnol Biochem 72:3289-92. 2008..The IAM partition coefficients (K(IAM)) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes...
Identification of metabolites in plasma and urine of Uruguayan propolis-treated ratsShigenori Kumazawa
Laboratory of Functional Food Science and COE Program in the 21st Century, School of Food and Nutritional Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
J Agric Food Chem 52:3083-8. 2004..These results suggest that flavonoids in propolis are metabolized and circulate in the body after oral administration of propolis...
Anthocyanin composition and antioxidant activity of the Crowberry (Empetrum nigrum) and other berriesKenjirou Ogawa
Graduate School of Nutritional and Environmental Sciences and Institute for Environmental Sciences, University of Shizuoka, Yada 52 1, Suruga ku, Shizuoka, 422 8526, Japan
J Agric Food Chem 56:4457-62. 2008..Additionally, crowberry is suggested to be associated with a reduction in the risk of developing chronic diseases because of its strong antioxidant activity...
Histone H3 methylation at lysine 4 on the SLC2A5 gene in intestinal Caco-2 cells is involved in SLC2A5 expressionYuko Inamochi
Laboratory of Nutritional Physiology, The University of Shizuoka, Graduate School of Nutritional and Environmental Sciences and Global COE, 52 1 Yada, Shizuoka shi, Shizuoka 422 8526, Japan
Biochem Biophys Res Commun 392:16-21. 2010..Our results suggest that methylation of histone H3 at K4 and acetylation of histones H3 and H4 are involved in SLC2A5 gene induction associated with intestinal differentiation of Caco-2 cells...
Proteomic identification of serum proteins associated with stress-induced gastric ulcers in fasted ratsAyako Kato
Graduate School of Nutritional and Environmental Sciences and Global COE Program, University of Shizuoka, Japan
Biosci Biotechnol Biochem 74:812-8. 2010..The findings suggest that these two serum proteins might be useful as biomarkers, CK-M for stress-induced gastric ulcer and ApoA4 for starvation...
Studies of the constituents of Uruguayan propolisShigenori Kumazawa
School of Food and Nutritional Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
J Agric Food Chem 50:4777-82. 2002..Thus, it is suggested that the Uruguayan propolis has a plant origin similar to those of propolis from Europe and China...
Mass spectroscopic characterization of protein modification by malondialdehydeTakeshi Ishii
Graduate School of Bioagricultural Sciences, Nagoya University, Chikusaku, Nagoya 464-8601, Japan
Chem Res Toxicol 19:122-9. 2006....
N(epsilon)-(3-methylpyridinium)lysine, a major antigenic adduct generated in acrolein-modified proteinAtsunori Furuhata
Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
J Biol Chem 278:48658-65. 2003..More notably, this condensation adduct appeared to be an intrinsic epitope of a monoclonal antibody 5F6 that had been raised against acrolein-modified protein...
Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: identification of modification sites in glyceraldehyde-3-phosphate dehydrogenaseTakeshi Ishii
Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
Biochemistry 42:3474-80. 2003....
Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2Takeshi Ishii
Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan
Chem Res Toxicol 17:1313-22. 2004..These results suggest that cysteine-targeted oxidation/thiolation plays a critical role in the regulation of protein function under conditions of electrophile-induced oxidative stress...
