Kohei Sawaki

Summary

Affiliation: Tokyo Dental College
Location: Chiba, Japan
Publications:
Expression of BMP7 is associated with resistance to diabetic stress: Comparison among mouse salivary glands.
2008, European Journal of Pharmacology, 596:1-5

Immunohistochemical study on GABAergic system in salivary glands.
2009, European Journal of Pharmacology, 610:18-22

Paradoxical effect of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on enhancing antitumor activity of cisplatin in ascites sarcoma 180 cells.
2010, Journal of Pharmacological Sciences, 112:361-368

Diazepam enhances production of diazepam binding inhibitor (DBI), a negative saliva secretion regulator, localized in rat salivary gland.
2011, Journal of Pharmacological Sciences, 115:221-229

Modulation of benzodiazepine receptor, adrenoceptor and muscarinic receptor by diazepam in rat parotid gland.
2011, European Journal of Pharmacology, 657:20-25

Publications

  1. ncbi Modulation of benzodiazepine receptor, adrenoceptor and muscarinic receptor by diazepam in rat parotid gland
    Kazunori Ouchi
    Department of Pharmacology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Eur J Pharmacol 657:20-5. 2011
  2. ncbi Expression of BMP7 is associated with resistance to diabetic stress: comparison among mouse salivary glands
    Masatake Izumi
    Department of Orthodontics, Tokyo Dental College, Chiba, Japan
    Eur J Pharmacol 596:1-5. 2008
  3. ncbi Immunohistochemical study on GABAergic system in salivary glands
    Yasuhiro Kosuge
    Department of Pharmacology and Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Eur J Pharmacol 610:18-22. 2009
  4. ncbi Diazepam enhances production of diazepam-binding inhibitor (DBI), a negative saliva secretion regulator, localized in rat salivary gland
    Eri Tsukagoshi
    Department of Pharmacology, Tokyo Dental College, Chiba 261 8502, Japan
    J Pharmacol Sci 115:221-9. 2011
  5. ncbi Paradoxical effect of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on enhancing antitumor activity of cisplatin in ascites sarcoma 180 cells
    Toshihiro Sato
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    J Pharmacol Sci 112:361-8. 2010
  6. ncbi [Adverse drug reactions and oral disorders]
    Mitsuru Kawaguchi
    Nippon Yakurigaku Zasshi 127:447-53. 2006
  7. ncbi Effects of anticonvulsants on local anaesthetic-induced neurotoxicity in rats
    K Sawaki
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    Pharmacol Toxicol 86:59-62. 2000
  8. ncbi Evaluation of high-performance liquid chromatography and mass spectrometry method for pharmacokinetic study of local anesthetic ropivacaine in plasma
    Kohei Sawaki
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    Biomed Res 30:319-24. 2009
  9. ncbi Proteomic analysis of lipopolysaccharide-treated submandibular gland in rat
    Kohei Sawaki
    Department of Pharmacology, Tokyo Dental College, Miham ku, Chiba, Japan
    Bull Tokyo Dent Coll 52:31-7. 2011
  10. ncbi [Drug-induced taste disorder]
    Mitsuru Kawaguchi
    Department of Pharmacology, Tokyo Dental College
    Nippon Rinsho 65:497-503. 2007

Collaborators

Detail Information

Publications10

  1. ncbi Modulation of benzodiazepine receptor, adrenoceptor and muscarinic receptor by diazepam in rat parotid gland
    Kazunori Ouchi
    Department of Pharmacology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Eur J Pharmacol 657:20-5. 2011
    ....
  2. ncbi Expression of BMP7 is associated with resistance to diabetic stress: comparison among mouse salivary glands
    Masatake Izumi
    Department of Orthodontics, Tokyo Dental College, Chiba, Japan
    Eur J Pharmacol 596:1-5. 2008
    ..These results suggest that BMP7 acts to prevent diabetic damage in salivary gland, and that its cytoprotective effect is closely correlated with mRNA levels in tissue...
  3. ncbi Immunohistochemical study on GABAergic system in salivary glands
    Yasuhiro Kosuge
    Department of Pharmacology and Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
    Eur J Pharmacol 610:18-22. 2009
    ..These results indicate that GAD67 is present around acinar cells in the salivary glands, and suggest that the GABAergic system in the glands is closely related to the autonomic nervous system...
  4. ncbi Diazepam enhances production of diazepam-binding inhibitor (DBI), a negative saliva secretion regulator, localized in rat salivary gland
    Eri Tsukagoshi
    Department of Pharmacology, Tokyo Dental College, Chiba 261 8502, Japan
    J Pharmacol Sci 115:221-9. 2011
    ..These results suggest that repetitive administration of DZP stimulates DBI production, which may result in an increase in the suppressive effect of DZP on salivary secretion...
  5. ncbi Paradoxical effect of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on enhancing antitumor activity of cisplatin in ascites sarcoma 180 cells
    Toshihiro Sato
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    J Pharmacol Sci 112:361-8. 2010
    ..The results also suggest that the enhancing effect of DMPS is closely related to a decrease in [Ca(2+)](i) and that the suitable dose and adequate administrational time of DMPS are important for its effective action...
  6. ncbi [Adverse drug reactions and oral disorders]
    Mitsuru Kawaguchi
    Nippon Yakurigaku Zasshi 127:447-53. 2006
  7. ncbi Effects of anticonvulsants on local anaesthetic-induced neurotoxicity in rats
    K Sawaki
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    Pharmacol Toxicol 86:59-62. 2000
    ..These results suggest that the benzodiazepines are effective drugs to prevent neurotoxicity induced by local anaesthetics, while phenytoin and primidone potentiate them...
  8. ncbi Evaluation of high-performance liquid chromatography and mass spectrometry method for pharmacokinetic study of local anesthetic ropivacaine in plasma
    Kohei Sawaki
    Department of Pharmacology, Tokyo Dental College, Chiba, Japan
    Biomed Res 30:319-24. 2009
    ....
  9. ncbi Proteomic analysis of lipopolysaccharide-treated submandibular gland in rat
    Kohei Sawaki
    Department of Pharmacology, Tokyo Dental College, Miham ku, Chiba, Japan
    Bull Tokyo Dent Coll 52:31-7. 2011
    ....
  10. ncbi [Drug-induced taste disorder]
    Mitsuru Kawaguchi
    Department of Pharmacology, Tokyo Dental College
    Nippon Rinsho 65:497-503. 2007