Research Topics
| S OishiSummaryAffiliation: Tokyo Metropolitan Research Laboratory of Public Health Country: Japan Publications
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Detail Information
Publications
Effects of propyl paraben on the male reproductive systemS Oishi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, 3 24 1, Hyakunin cho, Shinjuku ku, Japan
Food Chem Toxicol 40:1807-13. 2002..The exposure level at which this effect was observed is the same as the upper-limit acceptable daily intake (10 mg/kg body weight/day) of parabens in the European Community and Japan...- Effects of butylparaben on the male reproductive system in ratsS Oishi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Japan
Toxicol Ind Health 17:31-9. 2001..The results of the present experiments show for the first time that exposure of a postweaning mammal to butylparaben had an adverse effect on the secretion of testosterone and in the functions of the male reproductive system... - Effects of butyl paraben on the male reproductive system in miceShinshi Oishi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, 3 24 1 Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
Arch Toxicol 76:423-9. 2002..00%. These data demonstrated that butyl paraben can exert an adverse effect on the male reproductive system at doses that are well below those of the accepted daily intake (ADI) in Japan... - Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 ratsO Takahashi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, 24 1, Hyakunincho 3 chome, Shinjuku ku, Tokyo 169 0073, Japan
Arch Toxicol 75:42-51. 2001..25% BPA group. Serum testosterone concentrations were not decreased in BPA-treated groups. These results indicate that BPA even at a level of 0.25% (235 mg/kg per day) is clearly toxic to male reproductive organs... - Disposition of orally administered 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A) in pregnant rats and the placental transfer to fetusesO Takahashi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Tokyo, Japan
Environ Health Perspect 108:931-5. 2000..These results suggest that the absorption and distribution of BPA in maternal organs and fetuses are extremely rapid and that the placenta does not act as a barrier to BPA... - Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and miceO Takahashi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, 24 1 Hyakunincho 3 chome, Shinjuku ku, Tokyo 169 0073, Japan
Food Chem Toxicol 41:1035-44. 2003..Subcutaneous or intraperitoneal BPA is much more toxic on male reproductive and sex accessory organs than dietary... - Developmental toxicity of chlorpropham in miceT Tanaka
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Japan
Reprod Toxicol 11:697-701. 1997..The total incidence of external malformations was significantly increased in the two highest dose groups in a dose-related manner. Again brachyury was significantly increased in the 3000 mg/kg bw group... - Effects of ingestion of cadmium-polluted rice or low-dose cadmium-supplemented diet on the endogenous metal balance in female ratsS Oishi
Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Japan
Biol Trace Elem Res 84:155-67. 2001.... - Lack of spermatotoxic effects of methyl and ethyl esters of p-hydroxybenzoic acid in ratsShinshi Oishi
Department of Environmental Health and Toxicology, Tokyo Metropolitan Institute of Public Health, 3 24 1 Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
Food Chem Toxicol 42:1845-9. 2004..Neither compound exhibited anti-spermatogenic effects nor elicited changes in levels of testosterone, LH and FSH at a dose level of about 1000 mg/kg of body weight per day... - Male reproductive toxicity of four bisphenol antioxidants in mice and rats and their estrogenic effectOsamu Takahashi
Department of Toxicology Tokyo Metropolitan Research Laboratory of Public Health, 24 1, Hyakunincho 3 chome, 169 0073 Shinjuku ku, Tokyo, Japan
Arch Toxicol 80:225-41. 2006..These results suggest that BM and TM are weakly toxic, possibly through an estrogenic mechanism to male reproductive organs in mice as well as rats, while MM and ME may be the direct testicular toxins in rats but not mice... - Simultaneous production of homoanatoxin-a, anatoxin-a, and a new non-toxic 4-hydroxyhomoanatoxin-a by the cyanobacterium Raphidiopsis mediterranea SkujaMichio Namikoshi
Department of Ocean Sciences, Tokyo University of Fisheries, Konan, Minato ku, Tokyo 108 8477, Japan
Toxicon 42:533-8. 2003..It should be noted that this is the first report demonstrating the simultaneous production of anatoxin-a and homoanatoxin-a by the same strain of cyanobacterium... - Antiestrogenic effect of paradichlorobenzene in immature mice and ratsOsamu Takahashi
Department of Environmental Health and Toxicology, Tokyo Metropolitan Institute of Public Health, 24 1 Hyakunincho 3 chome, Shinjuku ku, Tokyo, 169 0073, Japan
Arch Toxicol 81:505-17. 2007..These results suggest that PDCB is a weak antiestrogenic/antiuterotrophic compound possibly due to ER modulation through arylhydrocarbon receptor...