Research Topics
Species | Makoto KawashimaSummaryAffiliation: Tokyo Women's Medical University Country: Japan Publications
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Detail Information
Publications
Quality of life in patients with atopic dermatitis: impact of tacrolimus ointmentMakoto Kawashima
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
Int J Dermatol 45:731-6. 2006..It may be an appropriate alternative for patients with AD and steroid phobia. The aim of this study was to determine the impact of AD on QOL and to investigate the effect of tacrolimus ointment on QOL in patients with steroid phobia...
Finasteride in the treatment of Japanese men with male pattern hair lossMakoto Kawashima
Tokyo Women s Medical University, School of Medicine, Department of Dermatology 8 1, Kawada cho, Shinjuku Tokyo, 162 8666 Japan
Eur J Dermatol 14:247-54. 2004..2 mg dose at 48 weeks. Finasteride treatment was generally well tolerated. Finasteride 1 mg\day slows hair loss and improves hair growth in Japanese men with male pattern hair loss...
Review of fexofenadine in the treatment of chronic idiopathic urticariaMakoto Kawashima
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
Int J Dermatol 41:701-6. 2002..Importantly, the lack of ethnic differences between the studies from North America and Asia indicate that the efficacy and safety of fexofenadine demonstrated in these studies are cross-culturally applicable...
Effect of standard medication on quality of life of patients with atopic dermatitisMakoto Kawashima
Department of Dermatology, Tokyo Women s Medical University, Shinjuku ku, Japan
J Dermatol 34:9-16. 2007..5%). These data suggest that patients with atopic dermatitis and associated pruritus experience significant improvements in both symptom severity and QOL when receiving standard therapy...
Evaluation of the newly established acne severity classification among Japanese and Korean dermatologistsNobukazu Hayashi
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 35:261-3. 2008..0% to 79.8% among Korean ones. These data show the adequacy of both our grading system itself and its presentation. We believe our classification will be one of the most effective and reasonable grading systems to classify acne severity...
Abnormal expression of the novel epidermal enzyme, glucosylceramide deacylase, and the accumulation of its enzymatic reaction product, glucosylsphingosine, in the skin of patients with atopic dermatitisMutsumi Ishibashi
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
Lab Invest 83:397-408. 2003..Thus, collectively these results strongly suggest the physiologic relevance of GC deacylase to the acylceramide deficiency seen in the stratum corneum of patients with AD...
Measurement of the impact of atopic dermatitis on patients' quality of life: a cross-sectional and longitudinal questionnaire study using the Japanese version of Skindex-16Yuko Higaki
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan
J Dermatol 31:977-82. 2004....
Two cases of desmoplastic trichoepitheliomaTakahiro Matsuki
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
J Dermatol 31:824-7. 2004..Histopathological comparison of the two specimens suggested that the clinical dimple in the center of the first tumor might be the result of stromal dystrophic changes induced by the tumor...
A double-blind, randomized, placebo-controlled, two-dose comparative study of botulinum toxin type A for treating glabellar lines in Japanese subjectsKiyonori Harii
Department of Plastic and Reconstructive Surgery, School of Medicine, Kyorin University, Mitaka shi, Tokyo, Japan
Aesthetic Plast Surg 32:724-30. 2008..The aim of this study was to characterize the safety and efficacy of 10-U and 20-U BoNTA doses versus placebo for treating glabellar lines in Japanese subjects...
Acne management in Japan: study of patient adherenceYoshiki Miyachi
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Dermatology 223:174-81. 2011..These data suggest that there is significant room for improvement in acne adherence in Japan, as in other areas of the world, and that improved education may enhance adherence...
A cross-sectional analysis of quality of life in Japanese acne patients using the Japanese version of Skindex-16Nobukazu Hayashi
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan
J Dermatol 31:971-6. 2004..To improve patients' quality of life, treatment of comedones should be fully respected. In addition, dermatologists should encourage patients to visit clinics regularly to help them improve the emotional aspects of their quality of life...
Japanese version of cutaneous body image scale: translation and validationYuko Higaki
Institute of Women s Health, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 36:477-84. 2009..These results suggest that the Japanese version of the CBIS is a reliable and valid instrument to measure the cutaneous body image of Japanese adults and also dermatology patients...
A single UVB exposure increases the expression of functional KIT in human melanocytes by up-regulating MITF expression through the phosphorylation of p38/CREBYuki Mizutani
Department of Dermatology, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjyuku, Tokyo, 162 8666, Japan
Arch Dermatol Res 302:283-94. 2010..These findings indicate that UVB stimulates functional KIT expression in human melanocytes via the up-regulation of MITF which is, in turn, due to the activation of p38 and CREB...
Mandibular alveolar bone necrosis after trigeminal herpes zosterJunko Arikawa
Department of Dermatology, Tokyo Women's Medical University, and Hoshino Dental Clinic, Tokyo, Japan
Int J Dermatol 43:136-7. 2004
Make-up improves the quality of life of acne patients without aggravating acne eruptions during treatmentsNobukazu Hayashi
Department of Dermatology, Tokyo Women s Medical University, Kawada cho 8 1, Shinjuku ku, Tokyo, 162 8666, Japan
Eur J Dermatol 15:284-7. 2005..The QOL scores of Skindex-16, GHQ30 and anxiety state index greatly improved. Our results suggest that dermatologists should encourage acne patients to utilize appropriate make-up to improve their QOL...
Prevalence of human papillomavirus DNA sequences in verrucous carcinoma of the lip: genomic and therapeutic approachesTsuyoshi Mitsuishi
Department of Dermatology, Nippon Medical School, 1 1 5, Sendagi, Bunkyou ku, Tokyo 113 8603, Japan
Cancer Lett 222:139-43. 2005..In addition, the relationship between VC of the lip and HPV infection is discussed, as is therapy against VC...
Transforming growth factor beta and connective tissue growth factor are involved in the evolution of nevus of NantaTomoko Keida
Department of Dermatology, Seibo Hospital, Tokyo, Japan
J Dermatol 32:442-5. 2005..Positive staining for transforming growth factor-beta and connective tissue growth factor suggested the involvement of these growth factors in the ossification of nevus of Nanta...
Down-regulated PAR-2 is associated in part with interrupted melanosome transfer in pigmented basal cell epitheliomaKazuko Sakuraba
Department of Dermatology, Tokyo Women's Medical University, Tokyo
Pigment Cell Res 17:371-8. 2004..These findings suggest that the decreased expression of PAR-2 in the basaloid cells is associated in part with the observed interruption of melanosome transfer in pigmented BCE...
The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentationHideko Hattori
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Invest Dermatol 122:1256-65. 2004....
Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pyloriRei Akashi
Department of Dermatology Medical Research Institute, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 38:761-6. 2011..We suggest that H. pylori may be an important pathogenetic factor, especially for prurigo chronica multiformis, and that eradication therapy should be considered to treat intractable cases...
Establishment of grading criteria for acne severityNobukazu Hayashi
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 35:255-60. 2008..The appropriate divisions of inflammatory eruptions of half of the face to decide classifications were: 0-5, "mild"; 6-20, "moderate"; 21-50, "severe"; and more than 50, "very severe"...
Application of the Food and Drug Administration (FDA) bioequivalent guidance of topical dermatological corticosteroid in yellow-skinned Japanese population: validation study using a chromameterTomoko Keida
Department of Dermatology, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, Tokyo 162 8666, Japan
J Dermatol 33:684-91. 2006..However, negligible differences were found in our study regarding dose duration, reproducibility and seasonal change...
Efficacy of oral antibiotics on acne vulgaris and their effects on quality of life: a multicenter randomized controlled trial using minocycline, roxithromycin and faropenemNobukazu Hayashi
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 38:111-9. 2011..Our randomized controlled clinical trial suggested that MINO, RXM and FRPM were efficient to improve inflammatory acne and patient QOL, and there was no significant difference between them...
Partial lipodystrophy in a patient with systemic lupus erythematosusNaoko Ishiguro
Department of Dermatology, Tokyo Women s Medical University, Japan
Dermatology 204:298-300. 2002..The dose of prednisolone was increased to 10 mg/day and the lesions stopped spreading. Such partial lipodystrophy is distinct from lipoatrophy of lupus profundus...
Striaelike epidermal distension: a newly recognized cutaneous manifestation in acute leg edemaNaoko Ishiguro
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan
Arch Dermatol 138:641-2. 2002
Adapalene gel 0.1% is effective and safe for Japanese patients with acne vulgaris: a randomized, multicenter, investigator-blinded, controlled studyMakoto Kawashima
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol Sci 49:241-8. 2008..However, there are currently no topical retinoids available for the treatment of acne vulgaris in Japan...
Sphingosylphosphorylcholine is a Melanogenic Stimulator for Human MelanocytesKazuhiko Higuchi
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
Pigment Cell Res 16:670-8. 2003..These results suggest that SPC may be a melanogenic stimulator of human melanocytes inducing the coordinated upregulated expression of various melanogenic molecules, including c-kit...
A case of Weber-Christian disease with later development of rheumatoid arthritisYuki Nanke
Institute of Rheumatology, Tokyo Women s Medical University, Tokyo, Japan
Nihon Rinsho Meneki Gakkai Kaishi 34:49-52. 2011..This is the second case of WCD showing the subsequent development of RA, successfully treated with MTX, in the English literature. This case may provide clinical insight into WCD and RA...
Cutaneous granulomas associated with adult T-cell leukemia/lymphomaYuko Higaki
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
Dermatology 206:157-60. 2003..We believe that the patient initially had an unusual cutaneous type of ATL in which granulomas occurred as a host-protective response against ATL progression...
Human papillomavirus type 7-associated condylomaToshihiko Matsukura
National Institute of Infectious Diseases, Department of Dermatology, Nippon Medical School, Tokyo, Japan
Dermatology 221:5-8. 2010....
The Japanese version of Skindex-16: a brief quality-of-life measure for patients with skin diseasesYuko Higaki
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
J Dermatol 29:693-8. 2002..In conclusion, we have developed a semantically equivalent translation of Skindex-16 into Japanese. It is a reliable and valid measure of the effects of skin disease on the quality of life in Japanese patients...
A case of symptomatic primary HIV infectionSatomi Kobayashi
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo 162-8666, Japan
J Dermatol 32:137-42. 2005..Our findings suggested that CD8+ T cells and their interaction with CD1a+ dendritic cells in the skin may be important in inducing skin manifestations in acute HIV infections...
Eosinophilic pustular folliculitis following autologous peripheral blood stem-cell transplantationTomoko Keida
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
J Dermatol 31:21-6. 2004..EPF with HIV-negative hematological disease can be classified as a unique group in EPF...
Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnesYuko Takenaka
Department of Dermatology, Tokyo Women s Medical University, Tokyo, Japan
J Dermatol 39:350-4. 2012..01). Our results demonstrate that glycolic acid has moderate growth inhibitory and bactericidal effects on P. acnes, and that chemical peeling with glycolic acid works on inflammatory acne via those effects...
Human papillomavirus infection in actinic keratosis and bowen's disease: comparative study with expression of cell-cycle regulatory proteins p21(Waf1/Cip1), p53, PCNA, Ki-67, and Bcl-2 in positive and negative lesionsTsuyoshi Mitsuishi
Department of Dermatology, Nippon Medical School, Tokyo, Japan
Hum Pathol 34:886-92. 2003....
Cutaneous polyarteritis nodosa: a report of 16 cases with clinical and histopathological analysis and a review of the published workNaoko Ishiguro
Department of Dermatology, Tokyo Women s Medical University, Tokyo 162 8666, Japan
J Dermatol 37:85-93. 2010....
Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitisReiko Okamoto
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
J Lipid Res 44:93-102. 2003..These findings strongly suggest the physiological relevance of SM deacylase function in vivo to the ceramide deficiency found in the skin of patients with AD...
Increased expression of CD208 (DC-LAMP) in epidermal keratinocytes of psoriatic lesionsMegumu Higaki
Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan
J Dermatol 36:144-9. 2009..Additionally, these CD208-positive keratinocytes possessing putative antigen-processing activity might play a key role as antigen-presenting cells in psoriatic skin...
An open-label, randomized, 64-week study repeating 10- and 20-U doses of botulinum toxin type A for treatment of glabellar lines in Japanese subjectsMakoto Kawashima
Department of Dermatology, Tokyo Women s Medical University, Japan
Int J Dermatol 48:768-76. 2009..Repeated botulinum toxin type A (BoNTA) treatment typifies clinical practice. The long-term safety and efficacy should be demonstrated in diverse populations...
Cutaneous allergic reaction to heparins: subcutaneous but not intravenous provocationMaria Maroto-Iitani
Department of Dermatology, Tokyo Women's Medical University, Japan
Contact Dermatitis 52:228-30. 2005
Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureusJunko Arikawa
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan; Kao Biological Science Laboratories, Tochigi, Japan
J Invest Dermatol 119:433-9. 2002....
Ofuji's disease: a report on 20 patients with clinical and histopathologic analysisNaoko Ishiguro
Department of Dermatology, Tokyo Women's Medical University, Japan
J Am Acad Dermatol 46:827-33. 2002..CONCLUSIONS: Indomethacin is an effective therapy for Ofuji's disease. Tryptase-positive and chymase-negative mast cells might play some role in the pathogenesis of Ofuji's disease...
Treatment of localized epidermodysplasia verruciformis with tacalcitol ointmentJunko Hayashi
Department of Dermatology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama-ken, Japan
Int J Dermatol 41:817-20. 2002
A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skinMasako Katsuyama
Life Science Research Center, Shiseido Co Ltd, Tsuzuki ku, Yokohama, Japan
J Dermatol Sci 38:207-13. 2005..We found that xylitol (X) and farnesol (F) synergistically inhibited biofilm formation by SA and dissolved biofilm formed in vivo (Part 1)...
Possible involvement of T cell co-stimulation in pustulosis palmaris et plantaris via the induction of inducible co-stimulator in chronic focal infectionsHiroko Sakiyama
Department of Oral and corrected Maxillofacial Surgery, Tokyo Women s Medical University School of Medicine, Tokyo 162 8666, Japan
J Dermatol Sci 50:197-207. 2008..Chronic focal infections are closely related to pustulosis palmaris et plantaris (PPP), but the involvement of ICOS in PPP has not been clarified...
[Skin barrier dysfunction in atopic dermatitis]Makoto Kawashima
Department of Dermatology, Tokyo Women's Medical University
Nippon Rinsho 63:86-90. 2005
