Research Topics
| R SakakibaraSummaryAffiliation: Toho University Country: Japan Publications
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Detail Information
Publications
Correlation of right frontal hypoperfusion and urinary dysfunction in iNPH: a SPECT studyRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Neurourol Urodyn 31:50-5. 2012..To elucidate the pathophysiology of urinary dysfunction in idiopathic normal-pressure hydrocephalus (iNPH) by single-photon emission computed tomography (SPECT) and statistical brain mapping...
Effects of milnacipran and paroxetine on overactive bladder due to neurologic diseases: a urodynamic assessmentRyuji Sakakibara
Division of Neurology, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Urol Int 81:335-9. 2008....
Isolated facio-lingual hypoalgesia and weakness after a hemorrhagic infarct localized at the contralateral operculumRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
J Neurol Sci 276:193-5. 2009..Neuroimaging findings for our patient suggested the involvement of the primary somatosensory-motor cortices (S1 and M1) and the secondary somatosensory cortex (S2), which receive trigemino-thalamo-cortical pathways...
Dementia and lower urinary dysfunction: with a reference to anticholinergic use in elderly populationRyuji Sakakibara
Department of Internal Medicine, Neurology Division, Sakura Medical Center, Toho University, Sakura, Chiba, Japan
Int J Urol 15:778-88. 2008..In the future, studies seeking treatment regimens for an elderly individual with both dementia and urinary dysfunction are warranted...
Prevalence and mechanism of bladder dysfunction in Guillain-Barré SyndromeRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Neurourol Urodyn 28:432-7. 2009..To examine the prevalence and mechanism of urinary dysfunction in GBS...
Urinary retention without tetraparesis as a sequel to spontaneous spinal epidural hematomaRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Japan
Intern Med 47:655-7. 2008..It is postulated that the descending micturition pathways (just inside the pyramidal tracts) were selectively affected, while the ascending micturition pathways (the dorsal columns) were preserved in the present case...
Bladder and bowel dysfunction in Parkinson's diseaseR Sakakibara
Department of Internal Medicine, Toho University, Sakura, Japan
J Neural Transm 115:443-60. 2008..These treatments might be beneficial not only in maximizing patients' quality of life, but also in promoting intestinal absorption of levodopa and avoiding gastrointestinal emergency...
Mechanism of bladder dysfunction in idiopathic normal pressure hydrocephalusRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Neurourol Urodyn 27:507-10. 2008..To elucidate the mechanism of bladder dysfunction in idiopathic normal pressure hydrocephalus (iNPH) by a urodynamic study...
Genitourinary dysfunction in Parkinson's diseaseRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Shimoshizu, Sakura 285 8741, Japan
Mov Disord 25:2-12. 2010..Phosphodiesterase inhibitors are used to treat sexual dysfunction in PD. These treatments might be beneficial in maximizing the patients' quality of life...
Aseptic meningitis as the sole manifestation of Behçet's diseaseRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, 564 1 Shimoshizu, Sakura, 285 8741, Japan
Neurol Sci 30:405-7. 2009..Behçet's disease should be listed as a differential diagnosis of acute aseptic meningitis because, in acute aseptic meningitis caused by Behçet's disease, early treatment with corticosteroids could ameliorate this disorder...
Sphincter EMG as a diagnostic tool in autonomic disordersRyuji Sakakibara
Neurology Division, Dept of Internal Medicine, Sakura Medical Center, Toho University, 564 1 Shimoshizu, Sakura, Japan
Clin Auton Res 19:20-31. 2009..Sphincter EMG and relevant sacral autonomic tests are diagnostic tools for autonomic disorders, reflecting the common and significant involvement of the sacral cord in MSA...
Real-time measurement of oxyhemoglobin concentration changes in the frontal micturition area: an fNIRS studyRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Neurourol Urodyn 29:757-64. 2010..To explore brain activity in the frontal micturition area during natural bladder behavior...
Pelvic organ dysfunction is more prevalent and severe in MSA-P compared to Parkinson's diseaseT Yamamoto
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
Neurourol Urodyn 30:102-7. 2011..However, it is important to make a careful early-stage diagnosis. Therefore, we determined whether an examination of pelvic organ dysfunction would be helpful to distinguish between PD and MSA-P...
Urinary dysfunction in Brown-Séquard syndromeR Sakakibara
Department of Neurology, Chiba University School of Medicine, Chiba, Japan
Neurourol Urodyn 20:661-7. 2001..In conclusion, micturitional disturbance was not uncommon in our patients with BS, particularly in those with severe motor paresis, which could ameliorate by appropriate therapies...
Micturition disturbance in acute idiopathic autonomic neuropathyR Sakakibara
Department of Neurology, Chiba University School of Medicine, Chiba, Japan
J Neurol Neurosurg Psychiatry 75:287-91. 2004..To define the nature of micturition disturbance in patients with acute idiopathic autonomic neuropathy (AIAN)...
Reduced perfusion in the anterior cingulate cortex of patients with pure autonomic failure: an 123I-IMP SPECT studyS Hirano
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
J Neurol Neurosurg Psychiatry 80:1053-5. 2009..This study evaluated brain perfusion in patients with PAF by using N-isopropyl-p-(123)I iodoamphetamine ((123)I-IMP) single photon emission computed tomography (SPECT)...
Micturitional disturbance in a patient with neurosarcoidosisR Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 19:273-7. 2000..Prednisolone treatment again improved his urinary and neurological symptoms. The anteromedial frontal lobe lesion seems to be responsible for the micturitional disturbance in our patient with neurosarcoidosis...
Reduced cerebellar vermis activation during urinary storage and micturition in multiple system atrophy: 99mTc-labelled ECD SPECT studyR Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Eur J Neurol 11:705-8. 2004..In conclusion, it is suggested that the decrease in tracer activity in the cerebellar vermis during urinary storage and micturition is contributing to the micturitional disturbance in this disorder...
Urinary retention due to an isolated sacral root injury caused by sacral fractureR Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Spinal Cord 45:790-2. 2007..A case report...
Are alpha-blockers involved in lower urinary tract dysfunction in multiple system atrophy? A comparison of prazosin and moxisylyteR Sakakibara
Department of Neurology, Chiba University 1 8 1 Inohana Chuo ku, Chiba, Japan
J Auton Nerv Syst 79:191-5. 2000..These effects were common in patients with postural hypotension of more than -30 mmHg at trial entry (P<0.05). Modulation of alpha1-receptors may function in the management of lower urinary tract dysfunction in MSA...
Urinary retention can be the sole initial manifestation of acute myelitisA Hiraga
Department of Neurology, Chiba University Graduate School of Medicine, 1 8 8 Inohana, Chiba, Japan
J Neurol Sci 251:110-2. 2006..In those patients, when obstructive disease has been excluded, AM should be considered...
Short-term effect of a single levodopa dose on micturition disturbance in Parkinson's disease patients with the wearing-off phenomenonTomoyuki Uchiyama
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
Mov Disord 18:573-8. 2003....
Videomanometry of the pelvic organs: a comparison of the normal lower urinary and gastrointestinal tractsTakashi Ito
Department of Neurology, Chiba University, Chiba, Japan
Int J Urol 13:29-35. 2006..These features can aid in understanding the possible rectal 'artifacts' of videourodynamics and neurogenic pelvic organ dysfunction...
Neobladder overactivity; an equivalent to spontaneous rectal contractionRyuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, 564 1 Shimoshizu, Sakura, Japan
Int J Urol 14:1054-6. 2007..Bowel-targeted management may be necessary to minimize nocturnal enuresis in bladder-substituted patients...
Wolfram syndrome presenting marked brain MR imaging abnormalities with few neurologic abnormalitiesS Ito
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
AJNR Am J Neuroradiol 28:305-6. 2007..Patients with Wolfram syndrome may have discrepancies between neurologic and radiologic findings...
Primary Sjogren's syndrome presenting with generalized autonomic failureR Sakakibara
Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan
Eur J Neurol 11:635-8. 2004..Autoimmune autonomic ganglionopathy was mostly responsible for her autonomic failure...
Combination of a cholinergic drug and an alpha-blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusorTomonori Yamanishi
Department of Urology, Dokkyo University, Mibu, Chiba, Japan
Int J Urol 11:88-96. 2004..The aim of the present study was to compare the effectiveness of a cholinergic drug, an alpha-blocker and combinations of the two for the treatment of underactive detrusor...
Incomplete emptying and urinary retention in multiple-system atrophy: when does it occur and how do we manage it?Takashi Ito
Department of Neurology, Chiba University, Chiba, Japan
Mov Disord 21:816-23. 2006..Urethra-oriented medication and surgery benefit patients who would have difficulty performing CISC, although careful consideration of the short-term efficacy and potential adverse effects of these alternatives is mandatory...
[Urinary dysfunction in idiopathic normal pressure hydrocephalus]Ryuji Sakakibara
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Shimoshizu, Sakura, Chiba 285 8741, Japan
Brain Nerve 60:233-9. 2008..Functional UI can overlap the OAB/DO due secondary to impaired cognition/initiative, immobility, or disturbed consciousness in this disorder...
Urinary function in patients with corticobasal degeneration; comparison with normal subjectsRyuji Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 23:154-8. 2004..However, urinary function of this disorder has not been fully delineated. We investigated urinary function in patients with CBD...
Comparing bromocriptine effects with levodopa effects on bladder function in Parkinson's diseaseTomoyuki Uchiyama
Department of Neurology, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, Japan
Mov Disord 24:2386-90. 2009..With the exception of bladder outlet obstruction, these effects of bromocriptine are similar to the effects of L-dopa, albeit slightly less pronounced...
Thalamic infarction disrupts spinothalamocortical projection to the mid-cingulate cortex and supplementary motor areaMasahiko Kishi
Neurology Division, Department of Internal Medicine, Sakura Medical Center, Toho University, 564 1 Shimoshizu, Sakura, 285 8741, Japan
J Neurol Sci 281:104-7. 2009..Somatosensory-evoked potential findings were normal. The disruption of spinothalamocortical projection to the mid-CC and SMA is attributable to the development of central dysesthesia in the present case...
Micturitional disturbance in a patient with a spinal cavernous angiomaRyuji Sakakibara
Neurology Department, Chiba University, Chiba, Japan
Neurourol Urodyn 22:606-10. 2003..Lesions in the lateral and dorsal columns of the spinal cord seem to be responsible for the micturitional disturbance in our patient with spinal cavernous angioma...
Preliminary communication: urodynamic assessment of donepezil hydrochloride in patients with Alzheimer's diseaseRyuji Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 24:273-5. 2005..Donepezil hydrochloride, a central cholinergic drug, is widely used for improving cognitive decline in Alzheimer's disease (AD). We investigated whether donepezil might affect the lower urinary tract (LUT) function in AD...
Urinary dysfunction in patients with systemic lupus erythematosisRyuji Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 22:593-6. 2003..Seizures and psychiatric disorders are the most common manifestations; spinal cord lesions are uncommon. We had eight such patients who presented with urinary dysfunction...
Colonic transit time, sphincter EMG, and rectoanal videomanometry in multiple system atrophyRyuji Sakakibara
Department of Neurology, Chiba University, Chiba, Japan
Mov Disord 19:924-9. 2004..The responsible sites for these dysfunctions seem to be both central and peripheral nervous systems that regulate the LGIT...
Uroneurological assessment of spina bifida cystica and occultaRyuji Sakakibara
Department of Neurology, Chiba University School of Medicine, Chiba, Japan
Neurourol Urodyn 22:328-34. 2003..Herein, we report the results of uroneurological assessment in patients with spina bifida cystica and occulta, with respect to diagnosis and management of the disorders...
Loss of urinary voiding sensation due to herpes zosterAkiyuki Hiraga
Department of Neurology, Matsudo Municipal Hospital, Matsudo, Chiba, Japan
Neurourol Urodyn 22:335-7. 2003..This inconsistency is explained by the hypothesis that the number of urethral fibers is very small as compared to that of cutaneous fibers, therefore, urethral sensation would be more severely disturbed than cutaneous sensation...
Lower urinary tract dysfunctions in patients with spinal cord tumorsTomoyuki Uchiyama
Department of Neurology, Chiba University School of Medicine, Chiba, Japan
Neurourol Urodyn 23:68-75. 2004..CONCLUSION: Spinal cord tumors are commonly accompanied by LUTS. Clinical and urodynamic evaluation is crucial to diagnosis and management since there is little relationship between symptoms and findings...
Neurological diseases that cause detrusor hyperactivity with impaired contractile functionTatsuya Yamamoto
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 25:356-60. 2006..It has not previously been well known whether neurological diseases cause DHIC. We investigated which neurological diseases commonly cause DHIC in our laboratory...
Effects of electrical stimulation of the striatum on bladder activity in catsTatsuya Yamamoto
Department of Neurology, Chiba University, Chiba, Japan
Neurourol Urodyn 28:549-54. 2009..We assert that striatal dysfunction might contribute to the pathogenesis of detrusor overactivity in PD patients. However, the role of the striatum in bladder contraction remains unclear...
Questionnaire-based assessment of pelvic organ dysfunction in multiple system atrophyTatsuya Yamamoto
Department of Neurology, Chiba University, Chuo Ku, Chiba, Japan
Mov Disord 24:972-8. 2009..Pelvic organ dysfunction is common in MSA, and QOL is severely impaired in patients with MSA...
Good maternal and fetal outcomes of predominantly sensory Guillain-Barré syndrome in pregnancy after intravenous immunoglobulinYasuo Matsuzawa
Respiratory Diseases Division, Department of Internal Medicine, Sakura Medical Center, Toho University, Sakura, Japan
Neurol Sci 31:201-3. 2010....
Bladder sensation in peripheral nerve lesionsChiharu Yamaguchi
Central Laboratory Unit, Chiba University Hospital, Chiba, Japan
Neurourol Urodyn 25:763-9. 2006..A small proportion of patients with peripheral nerve lesions develop urinary urgency, presumably reflecting irritation of the afferent nerve fibers or the urothelium...
Urodynamic evaluation of surgical outcome in patients with urinary retention due to central lumbar disc prolapseTomonori Yamanishi
Department of Urology, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
Neurourol Urodyn 22:670-5. 2003..To investigate whether acute urinary retention due to central lumbar disc prolapse is reversible after emergency spinal surgery...
Pelvic autonomic dysfunction without paraplegia: a sequel of spinal cord strokeRyuji Sakakibara
Eur Neurol 60:97-100. 2008
Mechanism of abdominal massage for difficult defecation in a patient with myelopathy (HAM/TSP)Zhi Liu
J Neurol 252:1280-2. 2005
Urinary dysfunction and autonomic control in amyloid neuropathyTakashi Ito
Neurology Dept, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670, Japan
Clin Auton Res 16:66-71. 2006..The underlying mechanisms of urinary dysfunction seem to involve postganglionic cholinergic and afferent somatic nerves...
Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patientsZhi Liu
Department of Neurology, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670, Japan
Mov Disord 20:680-6. 2005....
Amezinium metilsulfate, a sympathomimetic agent, may increase the risk of urinary retention in multiple system atrophyRyuji Sakakibara
Department of Neurology, Chiba University, 1 8 1 Inohana Chuo ku, Chiba 260 8670, Japan
Clin Auton Res 13:51-3. 2003..05). Amezinium metilsulfate most probably stimulates both alpha1B-receptors in the vascular wall and alpha1A/D-receptors in the proximal urethra...
Acute urinary retention due to benign inflammatory nervous diseasesRyuji Sakakibara
Department of Neurology, Chiba University, 1 8 1 Inohana Chuo ku, 260 8670 Chiba, Japan
J Neurol 253:1103-10. 2006..Clinical features of sacral herpes or MRS differ markedly from those of the original "Elsberg syndrome" cases...
Lower urinary tract dysfunction in Machado-Joseph disease: a study of 11 clinical-urodynamic observationsRyuji Sakakibara
Department of Neurology, Chiba University, 1 8 1 Inohana Chuo, Chiba 260 8670, Japan
J Neurol Sci 218:67-72. 2004..However, lower urinary tract (LUT) dysfunction in MJD has not been fully delineated. We investigated LUT dysfunction in MJD by clinical-urodynamic observations...
Single-blind, randomized controlled study of the clinical and urodynamic effects of an alpha-blocker (naftopidil) and phytotherapy (eviprostat) in the treatment of benign prostatic hyperplasiaTomonori Yamanishi
Department of Urology, Dokkyo University, Mibu, Tochigi, Japan
Int J Urol 11:501-9. 2004..Eviprostat was used as a control to study the efficacy of naftopidil...
Dietary herb extract dai-kenchu-to ameliorates constipation in parkinsonian patients (Parkinson's disease and multiple system atrophy)Ryuji Sakakibara
Mov Disord 20:261-2. 2005
Do BPH patients have neurogenic detrusor dysfunction? A uro-neurological assessmentRyuji Sakakibara
Department of Neurology, Chiba University, Chiba Japan
Urol Int 74:44-50. 2005..We made an uro-neurological assessment in such patients in order to investigate the possibility of a concurrent NDD in patients diagnosed with BPH, and to correlate the presence of NDD with treatment outcome...
Is lumbar spondylosis a cause of urinary retention in elderly women?Ryuji Sakakibara
Neurology Dept, Chiba University, 1 8 1 Inohana Chuo ku, Chiba 260 8670, Japan
J Neurol 252:953-7. 2005..Lumbar spondylosis (LS) is a common spinal degenerative disorder which causes various types of lower urinary tract dysfunction (LUTD). However, it is not certain whether LS may cause urinary retention in elderly women...
Bilateral lesion in the lateral columns and complete urinary retention: association with the spinal cord descending pathway for micturitionAkiyuki Hiraga
Neurourol Urodyn 24:398-9. 2005
Meningitis-retention syndrome. An unrecognized clinical conditionRyuji Sakakibara
Dept of Neurology, Chiba University, 1 8 1 Inohana Chuo ku, Chiba 260 8670, Japan
J Neurol 252:1495-9. 2005..A combination of acute urinary retention and aseptic meningitis has not been well known. This combination can be referred to as meningitis-retention syndrome (MRS), when accompanied by no other abnormalities...
Psychogenic urinary dysfunction: a uro-neurological assessmentRyuji Sakakibara
Department of Neurology, Chiba University, and Central Laboratory Unit, Chiba University Hospital, Japan
Neurourol Urodyn 26:518-24. 2007..We here describe patients with PUD who were diagnosed in our uro- neurological laboratory...
Sporadic case of spinocerebellar ataxia type 17: treatment observations for managing urinary and psychotic symptomsKazuaki Kanai
Mov Disord 22:441-3. 2007
[Central nervous system disorders]Ryuji Sakakibara
Department of Neurology, Chiba University School of Medicine
Nippon Rinsho 60:315-21. 2002
