Moritoshi Kinoshita

Summary

Affiliation: Otsuka Pharmaceutical Co
Country: Japan

Publications

  1. ncbi Automated and simultaneous identification of microsatellite instability by fluorescence-based polymerase chain reaction (PCR) in four loci
    M Kinoshita
    Gene Diagnostic Center, Otsuka Assay Laboratories, Otsuka Pharmaceutical Co, Ltd, Tokushima, Japan
    Clin Chim Acta 279:15-23. 1999
  2. ncbi Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci
    Moritoshi Kinoshita
    Gene Analysis Center, Otsuka Assay Laboratories, Otsuka Life Science Initiative, Otsuka Pharmaceutical Co, Ltd, Tokushima, Japan
    Hepatology 36:433-8. 2002
  3. ncbi Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese
    Masayuki Matsunaga
    Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
    Drug Metab Dispos 37:699-701. 2009
  4. ncbi Endogenous tumor necrosis factor promotes resistance to cellular stresses by inducing the metallothionein-1A gene
    Tohru Hadama
    Gene Analysis Center, Otsuka Assay Laboratories, Otsuka Life Science Initiative, Otsuka Pharmaceutical Co, Ltd, 463 1, Kagasuno, Kawauchicyo, Tokushima 771 0129, Japan
    Anticancer Res 22:4059-63. 2002
  5. ncbi Reduced ING1b gene expression plays an important role in carcinogenesis of non-small cell lung cancer patients
    Kotaro Kameyama
    The Second Department of Surgery, Kagawa Medical University, Kagawa 761 0793, Japan
    Clin Cancer Res 9:4926-34. 2003
  6. ncbi Diverse p53 gene aberration in hepatocellular carcinoma detected by dual-color fluorescence in situ hybridization
    Masahiko Kondo
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Gastroenterol Hepatol 19:1066-73. 2004

Collaborators

Detail Information

Publications6

  1. ncbi Automated and simultaneous identification of microsatellite instability by fluorescence-based polymerase chain reaction (PCR) in four loci
    M Kinoshita
    Gene Diagnostic Center, Otsuka Assay Laboratories, Otsuka Pharmaceutical Co, Ltd, Tokushima, Japan
    Clin Chim Acta 279:15-23. 1999
    ..7%) of 19 patients with hereditary nonpolyposis colorectal cancer (HNPCC), meeting the Amsterdam Minimum Criteria, were found to exhibit MSI...
  2. ncbi Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci
    Moritoshi Kinoshita
    Gene Analysis Center, Otsuka Assay Laboratories, Otsuka Life Science Initiative, Otsuka Pharmaceutical Co, Ltd, Tokushima, Japan
    Hepatology 36:433-8. 2002
    ..In conclusion, underexpression of key gene products may be important in the development and/or progression of HCC...
  3. ncbi Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese
    Masayuki Matsunaga
    Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan
    Drug Metab Dispos 37:699-701. 2009
    ..These results suggest that these two CYP2D6*10 haplotypes are possible causes of interindividual variation in the activities and the substrate specificity of CYP2D6...
  4. ncbi Endogenous tumor necrosis factor promotes resistance to cellular stresses by inducing the metallothionein-1A gene
    Tohru Hadama
    Gene Analysis Center, Otsuka Assay Laboratories, Otsuka Life Science Initiative, Otsuka Pharmaceutical Co, Ltd, 463 1, Kagasuno, Kawauchicyo, Tokushima 771 0129, Japan
    Anticancer Res 22:4059-63. 2002
    ..We compared mRNA expression of various genes between MIAPaCa-2 human pancreatic cancer cells and M5 cells transduced with nonsecretory-type TNF gene expression vector...
  5. ncbi Reduced ING1b gene expression plays an important role in carcinogenesis of non-small cell lung cancer patients
    Kotaro Kameyama
    The Second Department of Surgery, Kagawa Medical University, Kagawa 761 0793, Japan
    Clin Cancer Res 9:4926-34. 2003
    ..We performed a clinical study on ING1b gene expression and p53 gene status in relation to p53 target genes...
  6. ncbi Diverse p53 gene aberration in hepatocellular carcinoma detected by dual-color fluorescence in situ hybridization
    Masahiko Kondo
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Gastroenterol Hepatol 19:1066-73. 2004
    ..Dual-color FISH is an effective method for detection of p53 gene aberration, and it can provide new insight into oncogenesis in HCC...