Research Topics
Species | Takaharu OueSummaryAffiliation: Osaka University Country: Japan Publications
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Detail Information
Publications
Pediatric thyroid cancer arising after treatment for pleuropulmonary blastomaTakaharu Oue
Department of Surgery, Division of Pediatric Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
Pediatr Blood Cancer 50:901-2. 2008..The patient has remained tumor-free for 3 years. The etiology and treatment of the uncommon combination of pleuropulmonary blastoma and thyroid carcinoma is discussed...- Total laparoscopic excision of retroperitoneal ganglioneuroma using the hanging method and a vessel-sealing deviceTakaharu Oue
Department of Surgery, Division of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
J Laparoendosc Adv Surg Tech A 18:779-82. 2008..Laparoscopic surgery is a safe, feasible method for the diagnosis and treatment of benign retroperitoneal tumors, such as ganglioneuroma... - Increased expression of multidrug resistance-associated genes after chemotherapy in pediatric solid malignanciesTakaharu Oue
Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
J Pediatr Surg 44:377-80. 2009.... - Outcome of pediatric renal tumor treated using the Japan Wilms Tumor Study-1 (JWiTS-1) protocol: a report from the JWiTS groupTakaharu Oue
Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
Pediatr Surg Int 25:923-9. 2009..This report reviews the results of JWiTS-1... - Increased expression of the hedgehog signaling pathway in pediatric solid malignanciesTakaharu Oue
Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
J Pediatr Surg 45:387-92. 2010..The present study was undertaken to examine the expression of the Hh signaling pathway in various pediatric tumors to elucidate the role of Hh signaling in pediatric malignancies... - Expression of Wilms tumor 1 gene in a variety of pediatric tumorsTakaharu Oue
Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
J Pediatr Surg 46:2233-8. 2011..The objectives of this study were to evaluate the WT1 gene expression in various pediatric tumors and to elucidate that WT1 can be a target of cancer therapy in pediatric malignancies... - Megatherapy with hematopoietic stem cell rescue as a preoperative treatment in unresectable pediatric malignanciesTakaharu Oue
Department of Pediatric Surgery, Department of Pediatrics, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 38:130-3; discussion 130-3. 2003..In the treatment of advanced pediatric malignancies, especially in the case of unresectable tumor, preoperative MT with SCT should be considered... - Can laparoscopic antireflux surgery improve the quality of life in children with neurologic and neuromuscular handicaps?Hisayoshi Kawahara
Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan
J Pediatr Surg 39:1761-4. 2004..Further refinements in diagnostic and treatment strategies are mandatory to improve the quality of life in such patients... - Hepatoblastoma in children of extremely low birth weight: a report from a single perinatal centerTakaharu Oue
Department of Pediatric Surgery, Pediatrics and Neonatology, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 38:134-7; discussion 134-7. 2003..The children with HB received perinatal treatments for a significantly longer time, which suggests that perinatal intensive and long-term medical treatments may be involved in the tumorigenesis in the highly sensitive immature liver... - Primary repair of tracheoesophageal fistula secondary to disc battery ingestion: a case reportHiroomi Okuyama
Department of Pediatric Surgery, Osaka Medical Center for Maternal and Child Health, Osaka, Japan
J Pediatr Surg 39:243-4. 2004..To the authors' knowledge, this is the first report of successful primary repair of a tracheoesophageal fistula secondary to disk battery ingestion... - The usefulness of videomanometry for studying pediatric esophageal motor diseaseHisayoshi Kawahara
Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan
J Pediatr Surg 39:1754-7. 2004..CONCLUSIONS: Videomanometry is helpful in interpreting manometric data by analyzing concurrent fluoroscopic images. Topographic analyses provide characteristic images reflecting motor abnormalities in pediatric esophageal disease... - Silencing of MYCN by RNA interference induces growth inhibition, apoptotic activity and cell differentiation in a neuroblastoma cell line with MYCN amplificationKeigo Nara
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
Int J Oncol 30:1189-96. 2007..Using RNAi method, the knock-down of MYCN expression induced growth-inhibition, apoptotic activity and cell differentiation in MYCN-amplified NB-1 cell line... - Retropharyngeal neuroblastoma in an infant: management without surgeryRisa Matsumura
Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan
J Pediatr Hematol Oncol 32:e160-3. 2010..Thus, it might be better to treat unresectable, localized disease accompanied by life-threatening symptoms with chemotherapy alone... - Hedgehog signal inhibitor forskolin suppresses cell proliferation and tumor growth of human rhabdomyosarcoma xenograftHiroaki Yamanaka
Division of Pediatric Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
J Pediatr Surg 46:320-5. 2011.... - Correlation between lung scintigraphy and long-term outcome in survivors of congenital diaphragmatic herniaHiroomi Okuyama
Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
Pediatr Pulmonol 41:882-6. 2006..503, P < 0.01; perfusion: R = 0.760, P < 0.0001). These results suggest that lung scintigraphy is useful to predict long-term pulmonary morbidity and poor nutritional status in survivors of CDH... - Esophageal motor function in congenital esophageal stenosisHisayoshi Kawahara
Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 38:1716-9. 2003..Swallow-induced LES relaxations were incomplete in FMS/TBR patients. CONCLUSIONS: The presence of gastroesophageal reflux and impaired esophageal motility are common in patients with CES... - Gastroesophageal reflux after repair of congenital diaphragmatic herniaMasafumi Kamiyama
Division of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 37:1681-4. 2002..CONCLUSION: An association of GER is not rare in early infancy after repair of CDH, which is influenced by the repair methods... - Intralesional sclerotherapy for subcutaneous venous malformations in childrenShuichiro Uehara
Division of Surgery, Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
Pediatr Surg Int 25:709-13. 2009..This report represents eight cases of children with VMs treated with direct percutaneous injections of sclerosing agents, such as ethanol, polidocanol or ethanolamine oleate... - Outpatient administration of radioactive iodine after total thyroidectomy for pediatric thyroid cancer: a report of three casesToru Takano
Department of Laboratory Medicine, Osaka University Graduate School of Medicine, 2 2 D2, Yamadaoka, Suita, Osaka, 565 0871, Japan
Int J Pediatr Otorhinolaryngol 73:1810-3. 2009..Thus, it is worth considering this therapy as a practical option for pediatric thyroid carcinoma in the countries in which outpatient administration of a large dose of (131)I is restricted... - Vaginal reconstruction in a patient with rhabdomyosarcoma previously treated by total vaginectomyTakeshi Kusafuka
Department of Pediatric Surgery, Osaka University Medical School, Suita, Osaka, Japan
J Pediatr Surg 37:1365-7. 2002..Because continuity from the vaginal introitus to the uterus was established, fertility can be expected for this patient... - Forskolin, a Hedgehog signal inhibitor, inhibits cell proliferation and induces apoptosis in pediatric tumor cell linesHiroaki Yamanaka
Department of Surgery, Division of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
Mol Med Report 3:133-9. 2010..These findings suggest that the Hh signaling pathway plays an important role in tumorigenesis and is a potential molecular target of new treatment strategies for these pediatric malignant tumors... - A case of childhood dermatofibrosarcoma protuberans of the faceKeigo Nara
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
J Pediatr Surg 46:1438-41. 2011..These operations were successfully performed, and the patient is alive without recurrence for 7 years... - P53 gene mutations in pleuropulmonary blastomasTakeshi Kusafuka
Department of Pediatric Surgery, Osaka University Medical School, Suita, Japan
Pediatr Hematol Oncol 19:117-28. 2002..The results raise the possibility that p53 inactivation can occur as a nonrandom genetic change involving the pathogenesis and outcome of PPB. Further studies in a larger series are necessary to clarify these matters... - In vitro construction of scaffold-free cylindrical cartilage using cell sheet-based tissue engineeringGakuto Tani
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, 565 0871, Japan
Pediatr Surg Int 26:179-85. 2010..This study developed a novel procedure to fabricate a scaffold-free cylindrical cartilage under in vitro conditions, while also evaluating the effect of a dynamic culture on the engineered construct... - Dumbbell-shaped Ewing's sarcoma family of tumor of thoracic spine in a childShuichiro Uehara
Department of Pediatric Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadagaoka, Suita, Osaka, Japan
Pediatr Surg Int 24:953-5. 2008..Very few cases of skeletal ESFT of epidural extension in childhood have been documented. Video-assisted thoracoscopic surgery remains the best option for the diagnosis of endothoracic tumors in children... - Inhaled nitric oxide with early surgery improves the outcome of antenatally diagnosed congenital diaphragmatic herniaHiroomi Okuyama
Department of Pediatric Surgery, Osaka Medical Center for Maternal and Child Health, Izumi, Osaka, Japan
J Pediatr Surg 37:1188-90. 2002..01). CONCLUSION: Our data suggest that early surgery and iNO improves the outcome and reduces the requirement of ECMO in the treatment of antenatally diagnosed CDH... - Glutamine prevents intestinal mucosal injury induced by cyclophosphamide in ratsMitsugu Owari
Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
Pediatr Surg Int 28:299-303. 2012..The purpose of the present study was to examine the effect of glutamine on mucosal damage induced by cyclophosphamide in a rat model, and to elucidate the mechanisms responsible for its protective effects...