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Genomes and Genes | Mineko MaedaSummaryAffiliation: Osaka University Country: Japan Publications
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Publications
A diffusible factor involved in MAP-kinase ERK2-regulated development of DictyosteliumM Maeda
Department of Biology, Graduate School of Science, Osaka University, Toyonaka, Japan
Dev Growth Differ 42:275-84. 2000..Considering the molecular mass and the mode of action, this factor could be a novel one. Possible targets of this factor are discussed in terms of cAMP-dependent protein kinase activation...- Changing patterns of gene expression in dictyostelium prestalk cell subtypes recognized by in situ hybridization with genes from microarray analysesMineko Maeda
Department of Biology, Graduate School of Science, Osaka University, Toyonaka, Osaka, Japan
Eukaryot Cell 2:627-37. 2003..These results indicate that differentiation of some aspects of PstO cells can occur in the absence of DIF-1... - Developmental changes in the spatial expression of genes involved in myosin function in DictyosteliumM Maeda
Department of Biology, Graduate School of Science, Osaka University, Machikaneyama 1 16, Toyonaka, Osaka, 560 0043, Japan
Dev Biol 223:114-9. 2000..However, expression of these genes was distinctively regulated in the early culminants. These findings suggest the existence of mechanisms responsible for the expression of particular genes... - Control of cell type proportioning in Dictyostelium discoideum by differentiation-inducing factor as determined by in situ hybridizationToshinari Maruo
Department of Biology, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan
Eukaryot Cell 3:1241-8. 2004..Removal of prespore cells resulted in cell type conversion in both wild-type and DIF-less anterior fragments. Thus, DIF-1 appears to act in concert with other processes to establish cell type proportions... - Defect in peroxisomal multifunctional enzyme MFE1 affects cAMP relay in DictyosteliumSatomi Matsuoka
Department of Biology, Graduate School of Science, Osaka University, 1-16 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
Dev Growth Differ 46:195-9. 2004..Thus, most of the developmental consequences of excess cyclopropane fatty acids appear to result from impaired cAMP relay... - Identification of new modes of Dd-STATa regulation of gene expression in Dictyostelium by in situ hybridisationNao Shimada
Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan
Int J Dev Biol 48:679-82. 2004..Again, this contrasts with markers derived from the paradigmatic, ecmA gene which are expressed normally in the Dd-STATa-null strain. The identification of these novel genes provides valuable tools to investigate the role of Dd-STATa... - Evidence that the Dictyostelium STAT protein Dd-STATa plays a role in the differentiation of inner basal disc cells and identification of a promoter element essential for expression in these cellsNao Shimada
Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba 274 8510, Japan
Differentiation 73:50-60. 2005..It also identifies aslA promoter elements that are likely to be regulated, directly or indirectly, by Dd-STATa... - Identification and characterization of novel calcium-binding proteins of Dictyostelium and their spatial expression patterns during developmentHaruyo Sakamoto
Department of Biology, Graduate School of Science, Osaka University, Machikaneyama cho 1 16, Toyonaka, Osaka 560 0043, Japan
Dev Growth Differ 45:507-14. 2003..Such distinct spatial expression patterns suggest that the CBP might be involved in morphogenesis and might have their own roles either in prespore or in prestalk cell differentiation of Dictyostelium... - Site-directed mutagenesis studies of bovine liver cytosolic dihydrodiol dehydrogenase: the role of Asp-50, Tyr-55, Lys-84, His-117, Cys-145 and Cys-193 in enzymatic activityT Terada
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, 1 6 Yamada oka, Suita, 565 0871, Osaka, Japan
Chem Biol Interact 130:833-45. 2001..Present results indicate that Cys-193 may play an important role in the modulation of enzymatic activity under redox conditions generated with GSH+GSSG among five cysteines in DD3... - Periodic signaling controlled by an oscillatory circuit that includes protein kinases ERK2 and PKAMineko Maeda
Department of Biology, Graduate School of Science, Osaka University, Machikaneyama cho 1 16, Toyonaka, Osaka 560 0043, Japan
Science 304:875-8. 2004..Similar oscillatory processes may occur in cells of many different species... - Extracellular matrix family proteins that are potential targets of Dd-STATa in Dictyostelium discoideumNao Shimada
Department of Biology, Faculty of Science, Toho University, 2 2 1 Miyama, Funabashi, Chiba 274 8510, Japan
J Plant Res 117:345-53. 2004..We discuss the potential role of Dd-STATa in morphogenesis via its effect on the interaction between cellulose and these extracellular matrix family proteins... - Beta-gamma subunit interaction is required for catalysis by H(+)-ATPase (ATP synthase). Beta subunit amino acid replacements suppress a gamma subunit mutation having a long unrelated carboxyl terminusC Jeanteur-De Beukelaer
Division of Biological Science, Osaka University, Japan
J Biol Chem 270:22850-4. 1995.... - Novel development rescuing factors (DRFs) secreted by the developing Dictyostelium cells, that are involved in the restoration of a mutant lacking MAP-kinase ERK2Masatsune Tsujioka
Department of Biology, Osaka University, Machikaneyama cho 101, Tyonaka, Osaka 560 0043, Japan
Zoolog Sci 21:829-34. 2004..Identification of these DRFs found in this study would provide insight into the mechanism by which the development of the erkB- mutant is restored and how these factors act in the normal development of Dictyostelium... - Periodic activation of ERK2 and partial involvement of G protein in ERK2 activation by cAMP in Dictyostelium cellsMineko Maeda
Biological Science, Osaka University, Toyonaka, Japan
Methods Mol Biol 346:469-78. 2006..In this chapter, we describe the methods we have used to assess the level of activated ERK2 and partial involvement of G protein in cAMP-induced ERK2 activation... - A novel gene trap method using terminator-REMI and 3' rapid amplification of cDNA ends (RACE) in DictyosteliumKosuke Takeda
Division of Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo, 060-0810, Hokkaido, Japan
Gene 312:321-33. 2003..Based on these results, we designated the method terminator-REMI. Using this method, we have generated a library of tagged Dictyostelium clones from which we have thus far isolated 242 developmental mutants... - Novel patterns of the gene expression regulation in the prestalk region along the antero-posterior axis during multicellular development of DictyosteliumYoko Yamada
Biological Science, Graduate School of Science, Osaka University, Machikaneyama 1 1, Toyonaka, Osaka 560 0043, Japan
Gene Expr Patterns 6:63-8. 2005..Heterogeneity was also observed in the core pstAB cells of the slug and immature stalk cells within the stalk tube. The upper- and lower-cups of a late culminant were also composed of several subdomains... - Molecular cloning of cDNA encoding the 16 KDa subunit of vacuolar H(+)-ATPase from mouse cerebellumH Hanada
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Biochem Biophys Res Commun 176:1062-7. 1991..The subunit had four transmembrane segments: Segment II and IV were highly homologous and Glu-139 was located in Segment IV. The roles of the non-conserved regions are discussed... - Mutational analyses of cysteine residues of bovine dihydrodiol dehydrogenase 3T Terada
Graduate School of Pharmaceutical Sciences, Osaka University, 1 6 Yamada oka, Suita, 565 0871, Osaka, Japan
Biochim Biophys Acta 1547:127-34. 2001..Our present results indicate that Cys193, which is located close to the NADP(+)-binding site, may be involved in the alteration of enzymatic activity... - Cloning of a lymphatic peptide/histidine transporterK Sakata
Department of Anatomy and Neuroscience, Graduate School of Medicine Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
Biochem J 356:53-60. 2001..These findings suggest that rPHT2 is involved in the protein catabolic pathway in the lymphatic system... - Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated proteinT Yoneda
Department of Anatomy, Osaka University Medical School, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
J Biol Chem 275:11114-20. 2000..The altered sensitivities to overexpressed Bcl10 may have been due to differences in signal responses to Bcl10 among cell types. Thus, Bcl10 was suggested to play crucial roles in the modulation of apoptosis associated with TRAF2... - Cloning and bacterial expression of monomeric short-chain dehydrogenase/reductase (carbonyl reductase) from CHO-K1 cellsT Terada
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Japan
Eur J Biochem 267:6849-57. 2000..RT-PCR of Chinese hamster tissues suggest that CHO-CR is highly expressed in kidney, testis, brain, heart, liver, uterus and ovary. Southern blotting analysis indicated the complexity of the Chinese hamster carbonyl reductase gene... - An ABC transporter homologous to TAP proteinsY Yamaguchi
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan
FEBS Lett 457:231-6. 1999..The similarity among these three proteins suggests that they could be derived from a common ancestral gene. Furthermore, we found that there is a potential splicing isoform, sharing the amino terminal 720 amino acid residues of TAPL... - Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genesS Tamura
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Proc Natl Acad Sci U S A 90:10876-80. 1993..These results clearly suggest that GATA-GT1 and GATA-GT2 are involved in gene regulation specifically in the gastric epithelium and represent two additional members of the GATA-binding protein family... - Characterization of multiple Chinese hamster carbonyl reductasesT Terada
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, 1 6 Yamada oka, Suita, Osaka, Japan
Chem Biol Interact 130:847-61. 2001..The results of Western blotting and RT-PCR suggest these CHCRs have a tissue-dependent-distribution in the Chinese hamster... - Control region and gastric specific transcription of the rat H+,K(+)-ATPase alpha subunit geneK Oshiman
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
FEBS Lett 281:250-4. 1991..Northern blot hybridization indicated that the gene was transcribed only in gastric mucosa... - Spatial expression patterns of genes involved in cyclic AMP responses in Dictyostelium discoideum developmentM Tsujioka
Department of Biology, Graduate School of Science, Osaka University, Machikaneyama-cho 1-16, Toyonaka, Osaka 560-0043, Japan
Dev Growth Differ 43:275-83. 2001..Promoter analyses of genes in particular classes should enhance understanding of the regulation of dynamic and coordinated gene expression during morphogenesis... - Beta subunit Glu-185 of Escherichia coli H(+)-ATPase (ATP synthase) is an essential residue for cooperative catalysisH Omote
Department of Biological Science, Osaka University, Japan
J Biol Chem 270:25656-60. 1995..P., Leslie, A.G.W., Lutter, R ., and Walker, J.E. (1994) Nature 370, 621-628).. - GATA-6 DNA binding protein expressed in human gastric adenocarcinoma MKN45 cellsT Yoshida
Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Osaka University, Suita, Japan
FEBS Lett 414:333-7. 1997..The conservation of the GATA protein binding sites suggests that they are important for the gene regulation of the human and rat H+/K+-ATPase... - Role of the amino terminal region of the epsilon subunit of Escherichia coli H(+)-ATPase (F0F1)M Jounouchi
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Arch Biochem Biophys 292:87-94. 1992.... - The rat H+/K(+)-ATPase beta subunit gene and recognition of its control region by gastric DNA binding proteinM Maeda
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
J Biol Chem 266:21584-8. 1991..The nuclear protein(s) are suggested to recognize three tandem GATAGC sequences and may be important for controlled transcription of the H+/K(+)-ATPase beta subunit gene in gastric parietal cells... - MFE1, a member of the peroxisomal hydroxyacyl coenzyme A dehydrogenase family, affects fatty acid metabolism necessary for morphogenesis in Dictyostelium sppSatomi Matsuoka
Department of Biology, Graduate School of Science, Osaka University, Toyonaka, Osaka, Japan
Eukaryot Cell 2:638-45. 2003..Hence, we propose that this enzyme plays an irreplaceable role in the survival strategy of Dictyostelium cells to form spores for their efficient dispersal in nature... - GATA DNA-binding protein expressed in mouse I-10 Leydig testicular tumor cellsR Nakagawa
Laboratory of Biochemistry and Molecular Biology, Osaka University, Osaka, Suita, 565-0871, Japan
Biochem Biophys Res Commun 283:412-6. 2001..Thus the conserved zinc finger domain of GATA proteins is suggested to contribute to the binding sequence preference. GATA-4 expressed in I-10 cells was not susceptible to proteolysis coupled with cAMP signaling... - H(+)-ATPase gamma subunit of Escherichia coli. Role of the conserved carboxyl-terminal regionA Iwamoto
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
J Biol Chem 265:5043-8. 1990.... - Mutations in Ser174 and the glycine-rich sequence (Gly149, Gly150, and Thr156) in the beta subunit of Escherichia coli H(+)-ATPaseA Iwamoto
Institute of Scientific and Industrial Research, Osaka University, Japan
J Biol Chem 266:16350-5. 1991..The possible location of the catalytic site including divalent cation binding site(s) is discussed... - Vacuolar type H(+)-ATPase genes: presence of four genes including pseudogenes for the 16-kDa proteolipid subunit in the human genomeM Hasebe
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Biochem Biophys Res Commun 183:856-63. 1992..Thus, it is interesting to know whether these genes are transcribed, since they may have unique cellular functions... - Kinetic studies of chromaffin granule H+-ATPase and effects of bafilomycin A1H Hanada
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Biochem Biophys Res Commun 170:873-8. 1990..This inhibitor not only lowered the rate of ATP hydrolysis at the single catalytic site, but also affected the catalytic cooperativity of the enzyme... - Amino acid sequence of the alpha and beta subunits of Methanosarcina barkeri ATPase deduced from cloned genes. Similarity to subunits of eukaryotic vacuolar and F0F1-ATPasesK Inatomi
Department of Biochemistry and Organic Chemistry, Osaka University, Japan
J Biol Chem 264:10954-9. 1989..coli enzyme were conserved in the methanogenic enzyme. This sequence conservation suggests that vacuolar, F1, methanogenic, and S. acidocaldarius ATPases were derived from a common ancestral enzyme... - A half-type ABC transporter TAPL is highly conserved between rodent and man, and the human gene is not responsive to interferon-gamma in contrast to TAP1 and TAP2A Kobayashi
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565 0871, Japan
J Biochem 128:711-8. 2000..3. Furthermore, the transcription of TAPL gene is not responsive to interferon-gamma, in contrast to TAP1 and TAP2. These results indicate that the gene regulation of TAPL is different from those of TAP1 and TAP2... - Gastric GATA-6 DNA-binding protein: proteolysis induced by cAMPR Nakagawa
Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Osaka University, Suita, Japan
FEBS Lett 408:301-5. 1997..This finding constitutes a novel aspect of regulation by GATA DNA-binding proteins, which are essential for developmental processes and tissue-specific transcription... - Purification and molecular cloning of mouse renal dipeptidaseS Satoh
Product Development Laboratories, Fujisawa Pharmaceutical Co, Ltd, Osaka, Japan
Biochim Biophys Acta 1163:234-42. 1993..From Northern blotting analysis, expression of the mouseRDP gene was recognized in both kidney and liver... - Transmembrane topology of Escherichia coli H(+)-ATPase (ATP synthase) subunit aH Yamada
Department of Biological Science, Institute of Scientific and Industrial Research, Osaka University, Japan
FEBS Lett 390:34-8. 1996..5%) or by sonication. These results suggest that at least parts of the three peptide segments of subunit a face the cytoplasm. Based on these observations, we propose a novel transmembrane topology of subunit a... - Molecular cloning of mouse Doc2alpha and distribution of its mRNA in adult mouse brainA Naito
Shionogi Institute for Medical Science, Settu shi, Osaka, Japan
Brain Res Mol Brain Res 44:198-204. 1997..These results indicate that Doc2alpha is expressed heterogeneously in mouse brain, where it is predominantly expressed in neuronal cells, and suggest that Doc2alpha plays a specific role in the area where it is expressed... - Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control regionM Maeda
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
J Biol Chem 265:9027-32. 1990.... - Structures of P-type transporting ATPases and chromosomal locations of their genesM Maeda
Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan
Cell Struct Funct 23:315-23. 1998..Identification of such regions and studies on the molecules playing role in their recognition may facilitate the unveiling of various cellular processes regulated by P-type ATPases... - Effects of lipopolysaccharide on a macrophage-like cell line (HS-P) from a rat histiocytic sarcomaJ Yamate
Department of Veterinary Pathology, Graduate School of Agriculture and Biological Science, Osaka Prefecture University, Gakuencho 1 1, Sakai, Osaka, 599 8531, Japan
J Comp Pathol 125:15-24. 2001..The study demonstrated that HS-P cells are highly LPS-responsive, indicating that they would be useful for studies of macrophage functions... - Mutational replacements of conserved amino acid residues in the alpha subunit change the catalytic properties of Escherichia coli F1-ATPaseS Soga
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Arch Biochem Biophys 268:643-8. 1989..The F1 from KF154 had lower multisite hydrolysis (about 10% of that of the wild type) but could support slow growth by oxidative phosphorylation... - Antibacterial activity of polyphenol components in oolong tea extract against Streptococcus mutansH Sasaki
Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan
Caries Res 38:2-8. 2004..These results suggest that the antibacterial activity of oolong tea extract is caused by a synergistic effect of monomeric polyphenols, which can easily bind to proteins... - Detection of the exogenous hGDNF in gerbils under the treatment with AxCAhGDNF adenoviral vectorT Yagi
Department of Neurosurgery, Osaka City University Medical School, Osaka, Japan
Brain Res Brain Res Protoc 8:88-98. 2001..In this paper, we describe in detail the techniques for the detection of the exogenous gene of hGDNF under the treatment with AxCAhGDNF... - cDNA cloning and sequence determination of pig gastric (H+ + K+)-ATPaseM Maeda
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
Biochem Biophys Res Commun 157:203-9. 1988..As the pig enzyme is advantageous for biochemical studies, the information of the primary structure is useful for further detailed studies... - Two genes, atpC1 and atpC2, for the gamma subunit of Arabidopsis thaliana chloroplast ATP synthaseN Inohara
Department of Organic Chemistry and Biochemistry, Osaka University, Japan
J Biol Chem 266:7333-8. 1991..J. Green, S. A. Kay, and N. H. Chau (1987) EMBO J. 6, 2543-2549). Consistent with these findings, an increased amount of the gamma subunit was detected immunochemically in illuminated plants... - A transcriptional profile of multicellular development in Dictyostelium discoideumNancy Van Driessche
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX 77030, USA
Development 129:1543-52. 2002..Our findings provide new perspectives on the complexity of the developmental program and the fraction of the genome that is regulated during development... - A STAT-regulated, stress-induced signalling pathway in DictyosteliumTsuyoshi Araki
School of Life Sciences, University of Dundee, Wellcome Trust Biocentre, Dow Street, Dundee, DD1 5EH, UK
J Cell Sci 116:2907-15. 2003..These data show that Dd-STATc functions as a transcriptional activator in a stress-response pathway and the pharmacological evidence, at least, is consistent with cGMP acting as a second messenger... - Analyses of cDNAs from growth and slug stages of Dictyostelium discoideumHideko Urushihara
Institute of Biological Sciences, University of Tsukuba, Tsukuba shi 305 8572, Japan
Nucleic Acids Res 32:1647-53. 2004..Genes encoding the enzymes of basic metabolism are mainly found in the common gene population. These results therefore suggest major differences between growing and developing Dictyostelium cells in the nature of the genes transcribed... - DIF-1, an anti-tumor substance found in Dictyostelium discoideum, inhibits progesterone-induced oocyte maturation in Xenopus laevisYuzuru Kubohara
Biosignal Research Center, Institute for Molecular and Cellular Regulation IMCR, Gunma University, Showa machi 3 39 15, Maebashi 371 8512, Japan
Eur J Pharmacol 460:93-8. 2003..These results indicate that DIF-1 inhibits progesterone-induced germinal vesicle breakdown possibly by blocking the progesterone-induced decrease in [cAMP](i) and the subsequent events in Xenopus oocytes... - A neutral ceramidase homologue from Dictyostelium discoideum exhibits an acidic pH optimumHatsumi Monjusho
Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
Biochem J 376:473-9. 2003....