Nobukazu Onishi

Summary

Country: Japan

Publications

  1. ncbi The ability of konjac-glucomannan to suppress spontaneously occurring dermatitis in NC/Nga mice depends upon the particle size
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co, Ltd, 2 2 8 Misasa cho, Nishi ku, Hiroshima 733 8510, Japan
    Biofactors 21:163-6. 2004
  2. ncbi A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: its oral intake suppresses spontaneously occurring dermatitis in NC/Nga mice
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co, Ltd, Hiroshima, Japan
    Int Arch Allergy Immunol 136:258-65. 2005
  3. ncbi Dietary pulverized konjac glucomannan suppresses scratching behavior and skin inflammatory immune responses in NC/Nga mice
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co Ltd, Hiroshima, Japan
    Int Arch Allergy Immunol 144:95-104. 2007
  4. ncbi Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co Ltd, Hiroshima, Japan
    Arch Dermatol Res 300:95-9. 2008
  5. ncbi Hydrolyzed Konjac glucomannan suppresses IgE production in mice B cells
    Hidenori Suzuki
    Department of Dermatology, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
    Int Arch Allergy Immunol 152:122-30. 2010
  6. ncbi Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization
    Yuhki Yanase
    Department of Dermatology, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, Japan
    Biochem Biophys Res Commun 387:435-9. 2009
  7. ncbi Dietary pulverized konjac glucomannan prevents the development of allergic rhinitis-like symptoms and IgE response in mice
    Nobukazu Onishi
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Japan
    Biosci Biotechnol Biochem 71:2551-6. 2007

Collaborators

Detail Information

Publications7

  1. ncbi The ability of konjac-glucomannan to suppress spontaneously occurring dermatitis in NC/Nga mice depends upon the particle size
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co, Ltd, 2 2 8 Misasa cho, Nishi ku, Hiroshima 733 8510, Japan
    Biofactors 21:163-6. 2004
    ..We concluded that the low-viscous GM possesses a novel immunoregulatory function and the intensity of the function depends upon the particle size rather than the viscosity...
  2. ncbi A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: its oral intake suppresses spontaneously occurring dermatitis in NC/Nga mice
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co, Ltd, Hiroshima, Japan
    Int Arch Allergy Immunol 136:258-65. 2005
    ..Our aims are to develop new physiological functions of low-viscous GM powder, pulverized GM or re-granulated fine GM, using a murine model of atopic dermatitis...
  3. ncbi Dietary pulverized konjac glucomannan suppresses scratching behavior and skin inflammatory immune responses in NC/Nga mice
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co Ltd, Hiroshima, Japan
    Int Arch Allergy Immunol 144:95-104. 2007
    ..This study aimed to examine the effects of PKGM on scratching behavior and skin inflammatory immune responses in NC/Nga mice...
  4. ncbi Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding
    Nobukazu Onishi
    Department of Research and Development, Nishikawa Rubber Co Ltd, Hiroshima, Japan
    Arch Dermatol Res 300:95-9. 2008
    ..Our results imply the possible involvement of autoimmunity on the pathogenesis of dermatitis and hyper-IgE syndrome in NC/Nga mice. PKGM might be effective in preventing autoimmune responses in AD...
  5. ncbi Hydrolyzed Konjac glucomannan suppresses IgE production in mice B cells
    Hidenori Suzuki
    Department of Dermatology, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
    Int Arch Allergy Immunol 152:122-30. 2010
    ..To elucidate the mechanism of action of pulverized KGM, we solubilized KGM and studied its effect on IgE in vitro and in vivo...
  6. ncbi Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization
    Yuhki Yanase
    Department of Dermatology, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1 2 3, Kasumi, Minami Ku, Hiroshima, Japan
    Biochem Biophys Res Commun 387:435-9. 2009
    ..These results indicate that fucoidan inhibits the increase of plasma IgE through the suppression of IgE-producing B cell population, and the effect of fucoidan in vivo is crucially dependent on the route and timing of its administration...
  7. ncbi Dietary pulverized konjac glucomannan prevents the development of allergic rhinitis-like symptoms and IgE response in mice
    Nobukazu Onishi
    Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Japan
    Biosci Biotechnol Biochem 71:2551-6. 2007
    ..These results suggest that PKGM can be a beneficial foodstuff in preventing nasal allergy such as seasonal pollinosis...