Yohei Maeshima

Summary

Affiliation: Okayama University
Country: Japan

Publications

  1. ncbi Angiogenesis and chronic kidney disease
    Yohei Maeshima
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Fibrogenesis Tissue Repair 3:13. 2010
  2. ncbi Acatalasemia sensitizes renal tubular epithelial cells to apoptosis and exacerbates renal fibrosis after unilateral ureteral obstruction
    Reiko Sunami
    Okayama Univ Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Am J Physiol Renal Physiol 286:F1030-8. 2004
  3. ncbi Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis
    Daisuke Saito
    Dept of Medicine and Clinical Science, Okayama Univ Graduate School of Medicine and Dentistry, Okayama, 700 8558, Japan
    Am J Physiol Renal Physiol 300:F873-86. 2011
  4. ncbi Sensitization to alloxan-induced diabetes and pancreatic cell apoptosis in acatalasemic mice
    Yoko Kikumoto
    Department of Medicine and Clinical Science, 2 5 1 Shikata cho, Kita ku, Okayama 700 8558, Japan
    Biochim Biophys Acta 1802:240-6. 2010
  5. ncbi Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice
    Mizuho Kobayashi
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Kidney Int 68:1018-31. 2005
  6. ncbi Unique microstructures and podocytic infolding in glomerular basement membrane associated with collagen diseases: a report of three cases
    Hitoshi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan
    Clin Exp Nephrol 12:450-4. 2008
  7. ncbi Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Rheumatol 33:1545-52. 2006
  8. ncbi Glomerular cell apoptosis in human lupus nephritis
    Hirofumi Makino
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, 700 8558 Okayama, Japan
    Virchows Arch 443:67-77. 2003
  9. ncbi Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice
    Hitoshi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Nephrol Dial Transplant 20:2670-80. 2005
  10. ncbi Increased susceptibility to oxidant-mediated tissue injury and peritoneal fibrosis in acatalasemic mice
    Naomi Fukuoka
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan
    Am J Nephrol 28:661-8. 2008

Collaborators

  • H Makino
  • Hitoshi Sugiyama
  • Noriyoshi Masuoka
  • Ken Ei Sada
  • Naoki Kashihara
  • Minoru Satoh
  • Keiki Ogino
  • Eiji Matsuura
  • J Wada
  • H Matsubara
  • Yuko Okazaki
  • Kazunori Nishizaki
  • M Asanuma
  • Yoshiyuki Hiki
  • Hisashi Masuyama
  • Yasushi Yamasaki
  • Masaru Kinomura
  • Kunihiro Ichinose
  • Tatsuyuki Inoue
  • Kumiko Hirokoshi
  • Hiroshi Morinaga
  • Mizuho Kobayashi
  • Da Hong Wang
  • Hiroyuki Kitayama
  • Daisuke Saito
  • Tatsuyo Nasu
  • Yoko Kikumoto
  • Naomi Fukuoka
  • Yoshihiko Yamamoto
  • Da-Hong Wang
  • Yuki Takazawa
  • Reiko Sunami
  • Masashi Kitagawa
  • Keiichi Takiue
  • Hikaru Sonoda
  • Yasufumi Sato
  • Katsuyuki Tanabe
  • Shoichiro Kojo
  • Kazushi Nakao
  • Haruhito Adam Uchida
  • Shinji Kitamura
  • Kazuko Kobayashi
  • Shohei Kira
  • Naoko Hashimoto
  • Junko Kasahara
  • Tomoko Tsukinoki
  • Hiroko Yamasaki
  • Kunihiro Fukushima
  • Mizuho Saeki
  • Yoshiki Narimatsu
  • Hisashi Narimatsu
  • Hirofumi Akagi
  • Mie Maruyama
  • Kumiko Hirokoshi-Kawahara
  • Ryo Kodera
  • Hiroyuki Yanai
  • Kei-ichi Takiue
  • Kei Ichi Takiue
  • Yoshio Nakamura
  • Yoshihisa Hanayama
  • Yan Wu
  • Masanobu Kaihara
  • Hisanao Norii
  • Naoki Agata
  • Masao Yamada
  • Takeshi Sugaya
  • Yuji Hiramatsu
  • Naomi Toda
  • Katsumi Eguchi
  • Norio Ogawa
  • Tetsuya Onoda
  • Masahiro Odawara
  • Tatsuji Yasuda

Detail Information

Publications25

  1. ncbi Angiogenesis and chronic kidney disease
    Yohei Maeshima
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Fibrogenesis Tissue Repair 3:13. 2010
    ..Determining the disease stage at which therapy is most effective and developing an effective drug delivery system targeting the kidney will be essential for pro-or anti-angiogenic strategies for patients with CKD...
  2. ncbi Acatalasemia sensitizes renal tubular epithelial cells to apoptosis and exacerbates renal fibrosis after unilateral ureteral obstruction
    Reiko Sunami
    Okayama Univ Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Am J Physiol Renal Physiol 286:F1030-8. 2004
    ..This study demonstrates that catalase deficiency enhanced tubulointerstitial injury and fibrosis in a murine model of UUO and thus supports the protective role of catalase in this model...
  3. ncbi Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis
    Daisuke Saito
    Dept of Medicine and Clinical Science, Okayama Univ Graduate School of Medicine and Dentistry, Okayama, 700 8558, Japan
    Am J Physiol Renal Physiol 300:F873-86. 2011
    ....
  4. ncbi Sensitization to alloxan-induced diabetes and pancreatic cell apoptosis in acatalasemic mice
    Yoko Kikumoto
    Department of Medicine and Clinical Science, 2 5 1 Shikata cho, Kita ku, Okayama 700 8558, Japan
    Biochim Biophys Acta 1802:240-6. 2010
    ..Treatment with telmisartan may prevent the onset of alloxan-induced diabetes even under acatalasemic conditions...
  5. ncbi Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice
    Mizuho Kobayashi
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Kidney Int 68:1018-31. 2005
    ..Catalase is one of the important antioxidant enzymes regulating the levels of intracellular hydrogen peroxide and hydroxyl radical. The effect of catalase deficiency on progressive renal fibrosis has not been fully elucidated...
  6. ncbi Unique microstructures and podocytic infolding in glomerular basement membrane associated with collagen diseases: a report of three cases
    Hitoshi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan
    Clin Exp Nephrol 12:450-4. 2008
    ..The response to glucocorticoid therapy was favorable in two cases. The cause of these morphological changes in the GBM might be associated with autoimmune disorders...
  7. ncbi Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus
    Ken Ei Sada
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    J Rheumatol 33:1545-52. 2006
    ..We evaluated IR in association with plasma concentrations of adipocytokines in patients with SLE...
  8. ncbi Glomerular cell apoptosis in human lupus nephritis
    Hirofumi Makino
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, 700 8558 Okayama, Japan
    Virchows Arch 443:67-77. 2003
    ..These data suggest that apoptosis is increased, but not decreased in glomeruli from patients with lupus nephritis. The signals that could induce glomerular cell apoptosis in lupus nephritis will need to be identified...
  9. ncbi Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice
    Hitoshi Sugiyama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Nephrol Dial Transplant 20:2670-80. 2005
    ....
  10. ncbi Increased susceptibility to oxidant-mediated tissue injury and peritoneal fibrosis in acatalasemic mice
    Naomi Fukuoka
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Okayama, Japan
    Am J Nephrol 28:661-8. 2008
    ..Peritoneal fibrosis is a major complication leading to the loss of peritoneal function in patients undergoing peritoneal dialysis. However, the effect of catalase depletion on peritoneal fibrosis has not yet been investigated...
  11. ncbi Mesangial cell Fas ligand: upregulation in human lupus nephritis and NF-kappaB-mediated expression in cultured human mesangial cells
    Tomoko Tsukinoki
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Clin Exp Nephrol 8:196-205. 2004
    ..Fas ligand (FasL) is a well-known death factor; however, the role of FasL in the regulation of human glomerulonephritis remains unclear...
  12. ncbi Clinical significance of serum oxidized low-density lipoprotein/beta2-glycoprotein I complexes in patients with chronic renal diseases
    Junko Kasahara
    Department of Cell Chemistry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Nephron Clin Pract 98:c15-24. 2004
    ....
  13. ncbi Overexpression of angiotensin type 2 receptor ameliorates glomerular injury in a mouse remnant kidney model
    Naoko Hashimoto
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan
    Am J Physiol Renal Physiol 286:F516-25. 2004
    ..Taken together, our findings suggest that AT(2)R-mediated signaling may protect from glomerular injuries induced by (5/6)Nx and that overexpression of AT(2)R may serve as a potential therapeutic strategy for glomerular disorders...
  14. ncbi Clinical usefulness of a prognostic score in histological analysis of renal biopsy in patients with lupus nephritis
    Shoichiro Kojo
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama City, Okayama, 700 8558, Japan
    J Rheumatol 36:2218-23. 2009
    ..To evaluate active and chronic lesions in association with renal outcome according to the International Society of Nephrology/Renal Pathology Society classification in patients with lupus nephritis...
  15. ncbi Regulation of angiogenic factors in angiotensin II infusion model in association with tubulointerstitial injuries
    Hiroyuki Kitayama
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Am J Hypertens 19:718-27. 2006
    ....
  16. ncbi Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney
    Shinji Kitamura
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    FASEB J 19:1789-97. 2005
    ..These results suggest rKS56 cells possess character such as self-renewal, multi-plasticity and capability of tissue repair. rKS56 may possibly contribute to the future development of cell therapy for renal regeneration...
  17. ncbi 2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice
    Kunihiro Ichinose
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Diabetes 55:1232-42. 2006
    ..Taken together, these results demonstrate the potential use of NM-3 as a novel therapeutic agent for renal alterations in type 2 diabetes...
  18. ncbi Molecular mechanism of cell injury
    Yohei Maeshima
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Contrib Nephrol 139:32-43. 2003
  19. ncbi Differential expression of glycogenes in tonsillar B lymphocytes in association with proteinuria and renal dysfunction in IgA nephropathy
    Tatsuyuki Inoue
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
    Clin Immunol 136:447-55. 2010
    ..These data suggest the downregulation of beta3GalT in tonsillar B lymphocytes to be closely associated with the clinical characteristics of IgAN...
  20. ncbi Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model
    Kunihiro Ichinose
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama 700-8558, Japan
    Diabetes 54:2891-903. 2005
    ..These results demonstrate the potential use of antiangiogenic endostatin peptide as a novel therapeutic agent in diabetic nephropathy...
  21. ncbi Enhanced TGF-beta/Smad signaling in the early stage of diabetic nephropathy is independent of the AT1a receptor
    Yuko Okazaki
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Clin Exp Nephrol 11:77-87. 2007
    ..The aim of this study was to clarify the role of AII in the regulation of the TGF-beta system in the early stage of DN using AII type1a receptor-deficient(AT1a(-/-)) mice...
  22. ncbi Vasohibin-1, a negative feedback regulator of angiogenesis, ameliorates renal alterations in a mouse model of diabetic nephropathy
    Tatsuyo Nasu
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Diabetes 58:2365-75. 2009
    ..Vasohibin-1 (VASH-1) is a unique endogenous angiogenesis inhibitor that is induced in endothelial cells by proangiogenic factors. We investigated the therapeutic efficacy of VASH-1 in an early diabetic nephropathy model...
  23. ncbi A case of immunotactoid glomerulopathy exhibiting nephrotic syndrome successfully treated with corticosteroids and antihypertensive therapy
    Masaru Kinomura
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Clin Exp Nephrol 13:378-84. 2009
    ..This case demonstrates that accurate diagnosis of ITG may result in successful therapeutic outcome...
  24. ncbi Steroid pulse therapy impaired endothelial function while increasing plasma high molecule adiponectin concentration in patients with IgA nephropathy
    Haruhito Adam Uchida
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
    Nephrol Dial Transplant 21:3475-80. 2006
    ..53 +/- 0.04 nmol/ml, P < 0.05) were observed. CONCLUSIONS: GC pulse therapy impaired endothelial function while increasing plasma adiponectin levels, which may in turn restore the endothelial function in patients with IgA nephropathy...
  25. ncbi Increase of serum angiopoietin-2 during pregnancy is suppressed in women with preeclampsia
    Kumiko Hirokoshi
    Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Am J Hypertens 18:1181-8. 2005
    ....