R Ogawa

..Thus, mechanotransduction studies are useful for developing clinical approaches that reduce the skin tension around wounds or scars for the prevention and treatment of not only keloids but also hypertrophic scars...

..In this paper, we focus on adipose-derived stem cells and vascularized tissue regeneration within the context of tissue transplantation...

..This article presents an evidence-based review of previous articles and proposes algorithms for the treatment and prevention of hypertrophic scars and keloids...

..Since 1986, they have harvested 41 superficial cervical artery flaps of various types from 32 patients to reconstruct head and neck scar contractures and intractable ulcers...

..Thus, preoperative diagnostic imaging to identify the ingredients of implants may improve the treatment decision-making process. In this report, we created a clinical imaging index...

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..This cell population can be easily identified through fluorescence microscope, it should be an ideal source of ASCs for further experiments of stem cell biology and tissue engineering...

..Each anatomical territory was clearly seen and its area identified...

..89 times greater than those harvested from male mice. This suggests that the adipogenic differentiation of ASCs is closely related to sex differences...

..The necessary information includes necessary differentiation factors, cell scaffolds, and cell culture conditions. We reviewed the methodology for manufacturing cell constructs using ASCs for clinical applications...

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..In this study, we optimized the conditions for human cartilage induction using human adipose-derived stem cells (ASCs), collagen scaffolds, and cyclic HP treatment...

..Thus, we customized doses for various sites. This report describes our trial of postoperative radiation therapy...

..5) Povidone-iodine gel is recommended with a tie-over dressing. These procedures have been found to be extremely helpful for ensuring the success of skin-grafting procedures...

..However, additional studies into the maturation of neovascularization, the development of effective biomaterial, and the possibility of using stem cells will be needed before these techniques can be used in the clinical situation...

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..The flap size was 28 x 15 cm, and it survived completely. The cervico-mental angle was clear and esthetically pleasing, and not only the aesthetic results but also the functional results were excellent...

..Moreover, we have found that by using skin flaps (e.g., perforator flaps and propeller flaps), which release tension on the wound, in combination with postoperative radiotherapy, huge keloids can be successfully treated...

..Mechanoreceptor or MS nociceptor inhibition and mechanical force reduction should propel the development of novel methods for scar prevention and treatment...

..Intracranial amelanotic melanoma is very rare, and there have been few reports of melanoma with cyst...

..1 percent versus 13.5 percent, p = 0.0017). The results suggested that keloid sites with a high risk of recurrence should be treated with escalated radiation doses and posttreatment self-management...

..Here, we describe the microvascular augmented subdermal vascular network flaps that we have devised...

..Since this cell population can be easily identified through fluorescence microscopy, it may be an ideal source of ASCs for further experiments on stem cell biology and tissue engineering...

..The clinical application of microvascular augmented SVN flaps, both pedicled and free, is presented...

..It is the international classification, which should be used for the description and conception of these flaps...

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..This flap is more useful for providing colour and texture matches than a skin graft, and it is easier to harvest the flap than a free flap because it is a kind of skin flap...

..quot; We have employed these flaps to treat mild scar contractures in the axilla and cubital fossa. These methods are easily manipulated to restore function and improve aesthetics of scar contractures...

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..We also discuss and evaluate the various methods of reconstruction...

..The mechanisms by which the external or superficial actions of these treatments cause remission of a protruding scar may be related to mechanoreceptor (nociceptor and cellular mechanoreceptor) responses...

..These data suggest that the functional niche is reconstituted at least partly and that regenerated BM on the scaffold may be used as a portable source of HSCs...

..quot; This study was designed to investigate whether cardiac wall stabilization with an epicardial stabilizer could affect the interpretation of wall motion during coronary anastomosis without cardiopulmonary bypass...

..Accordingly, we tested the hypothesis that diabetic patients experience a greater reduction in core temperature during general anesthesia than nondiabetic patients...

..This study investigated the effect of potassium canrenoate (PC) on pituitary adrenocortical function in lower abdominal surgery under sevoflurane anesthesia...

..Cardiogenic pulmonary edema is a frequent cause of respiratory failure. We investigated whether milrinone improved lung compliance...

..The EP1 receptor antagonist significantly reduced hyperalgesia, allodynia, and c-fos positive cells. These findings suggested that EP1 receptor antagonists may have a role in treatment of neuropathic pain...

..Activation of the adenosine triphosphate sensitive mitochondrial potassium channel is involved in the cardioprotective effect of ISO, and the action of this agent has an acute"memory phase" like ischemic preconditioning...

..Because large amounts of human lipoaspirates are readily available, and their procurement induces only low morbidity, ASCs may be useful in future clinical cell-based therapy for periodontal disease...

..ASCs may be an ideal source for adipose tissue regeneration, which may in turn play an important role in augmentation surgery in surgically treated cancer or trauma patients...

..The authors report several cases of complications after this procedure. Several related issues are discussed...

..Subsequently, tissue specimens were harvested from the upper, middle, and lower sites of the flap for histologic analyses...

..However, studies on the safety of polyacrylamide hydrogel injection are limited and inconsistent. In the authors' experience, polyacrylamide hydrogel injections can induce complications...

..In this article, the authors discuss the arterial networks associated with this flap and present clinical cases...

..We suggest that bone marrow cells migrated outside of the bone marrow and differentiated into osteoblasts to make up the calluses...

..The Vascular Endothelial Growth Factor immunohistochemical staining was quantified. Furthermore, mesenchymal stem cells could be helpful in any prefabrication procedure in which neovascularization is indispensable...

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..The island flap has a wide rotation arc, and both the color and texture match are better for reconstructing contour-sensitive areas such as the chin and neck than those of free flaps harvested from distant sites...

..To optimise OAP flap design, it is important to determine the supra-fascial perforator directionality (SPD) of the three branches...

..In the present study, the authors discuss the clinical usefulness of these flaps. Moreover, through their anatomical study using cadavers, the authors attempted to clarify the mechanism of blood flow into these flaps...

..Further analysis of mechanotransduction signaling pathways may provide additional insight to improve skin tissue engineering methods and optimize our device...

..We have found this method to be useful for the reconstruction of small scar contractures in locations such as finger joints and interdigital spaces after skin grafting to treat extensive burns...

..This long vascular pedicle could be returned through the inside of the flap. Thus, this flap appears to be ideal for one-stage reconstructions of full-thickness upper lip defects...

..Application of this approach enables further investigation into the contribution of peripheral blood in normal and abnormal healing responses...

..While further experimental studies and clinical confirmation are needed, our hypothesis may provide new insights into the etiology and pathology of FPD of the skin, such as keloids and hypertrophic scars...

..Propofol-sevoflurane anaesthesia is advantageous in terms of haemodynamics, but disadvantageous in terms of seizure duration and recovery time. Propofol alone is most advantageous in terms of seizure duration...

..Thus, we analyzed the relationship between keloid growth patterns and stretching tension using a visualized finite element study...

..With accelerated wound healing seen with the vacuum-assisted closure device, the authors studied its effects on nerve fiber regeneration, nerve sprouting, and the stimulation of neuropeptides and neurotrophins...

..Although ONO-4007 mimics LPS in increasing vascular permeability, mechanisms of permeability change elicited by ONO-4007 were not identical to those of LPS...

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..We have achieved dynamic reconstruction by using a temporalis muscle-galea pedicled flap in 38 longstanding facial paralysis patients. Our results show that this is a good option in treating such patients...

..Severe infection or operative history may be the cause of irregularly shaped keloids. Thus, in the absence of significant infection or a surgical history, the shape of keloids may be determined uniquely by skin tension...

..In this paper, we report on two cases and describe the concept of using "perforator flaps" and "propeller flaps" together as what are called "perforator pedicled propeller (PPP) flaps."..

..We evaluated the changes in BV by general anaesthesia using simple and easy estimation methods...

..However, intravenous lignocaine medication for electroconvulsive therapy is potentially useful for reducing tachycardia in high-risk patients and reducing the severity of propofol injection pain in comparison with a placebo...

..IMPLICATIONS: Diltiazem can blunt acute hyperdynamic responses after electroconvulsive therapy, but seizure duration is also significantly reduced, possibly making this therapy less effective...

..619, p=0.019). We conclude that Lumbar CSF pressure was attenuated by oral premedication with 5 microg/kg clonidine. Clonidine also contributed to a significant correlation between preanesthetic mean blood pressure and CSF pressure...

..We performed SAB 16 times in this patient, and he complained of severe pain each time. We investigated which drug was best for treating such induced pain by administering various drugs to the patient...

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..Therefore, in this report, the authors studied in vitro gap junctional intercellular communication function and connexin expression in fibroblasts derived from keloid and hypertrophic scar patients...

..In this report, the authors performed a comparative study on apoptotic signal transduction in fibroblasts derived from keloids and hypertrophic scars...

..quot; In this report, we introduce expanded "Super-thin flaps" for reconstruction of the face and neck for the first time in a patient...

..The aim of this study was to investigate the biological differences between peripheral and central keloid areas...