Research Topics
| Takeharu KanedaSummaryAffiliation: Nippon Veterinary and Animal Science University Country: Japan Publications
| Collaborators |
Detail Information
Publications
Lack of cyclic nucleotide regulation of MBCQ-induced relaxation of rat ileal smooth muscleTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Animal Science University, 7 1 Kyonan cho 1 chome, Musashino, Tokyo 180 8602, Japan
J Smooth Muscle Res 39:47-54. 2003..However the inhibition of CCh-induced contraction by MBCQ may not involve cyclic nucleotides in rat ileal smooth muscle...
Inhibitory mechanism of papaverine on carbachol-induced contraction in bovine tracheaTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Animal Science University, Tokyo, Japan
J Pharmacol Sci 98:275-82. 2005....
Inhibitory mechanism of monensin on high K+-induced contraction in guniea-pig urinary bladderTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
J Pharmacol Sci 100:133-41. 2006..These results suggest that the relaxation mechanism of monensin in smooth muscle of urinary bladder may be an inhibition of oxidative metabolism...
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladderTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Animal Science University, Japan
J Vet Med Sci 67:659-65. 2005..In conclusion, the effect of PDE inhibitors in the guinea pig gall bladder was different from those in smooth muscles, such as the trachea, taenia coli, and aorta...
Effects of papaverine on twitches in mouse diaphragmTakeharu Kaneda
Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Tokyo, Japan
Pharmacology 86:273-80. 2010..Papaverine (30 and 100 ?M) and NaCN (1 mM) decreased creatine phosphate and ATP contents. These results suggest that the relaxing effects of papaverine on mouse diaphragm are mainly due to inhibition of aerobic energy metabolism...
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in guinea pig taenia coliTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Animal Science University, Musashino, Tokyo, Japan
J Vet Med Sci 66:1047-52. 2004..In conclusion, it was indicated that vinpocetine- or Ro20-1724-induced relaxation was correlated with cAMP but EHNA- or zaprinast- induced relaxation was correlated with cGMP...
Ibudilast-induced decreases in cytosolic Ca(2+) level and contraction in rat aortaTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
J Pharmacol Sci 104:311-8. 2007..These results suggested that ibudilast inhibited PE- and high K(+)-induced muscle contractions mainly by the inhibition of [Ca(2+)](i) level in endothelium-denuded rat aorta...
Effects of high-K+, Na+-deficient solution on contractility of the smooth muscles of the bovine tracheaTakeharu Kaneda
Division of Veterinary Pharmacology, Nippon Veterinary and Life Science University, Tokyo, Japan
J Vet Med Sci 68:1039-45. 2006..In conclusion, I-154 K+ solution induced-relaxation in the bovine trachea may be due to swelling of smooth muscle cells and the mechanism of swelling is probably involved in DIDS-sensitive anion movement...
Effects of various selective phosphodiesterase inhibitors on relaxation and cyclic nucleotide contents in porcine iris sphincterTakuya Yogo
Laboratory of Veterinary Surgery, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
J Vet Med Sci 71:1449-53. 2009..This indicates that vinpocetine-, milrinone- and Ro20-1724-induced relaxation is correlated with cAMP, while EHNA- and zaprinast- induced relaxation is correlated with cGMP in porcine iris sphincter...
Effects of high-K(+), Na(+)-deficient solution on contractility of the smooth muscles of the porcine tracheaTakeharu Kaneda
Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
J Vet Med Sci 71:1209-16. 2009..Moreover, the inhibition of glucose utilization in I-154 K(+) medium in porcine trachea is different from that of bovine trachea...
