Research Topics
Genomes and Genes | A NoseSummaryAffiliation: National Institute for Basic Biology Country: Japan Publications
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Detail Information
Publications
Neuromuscular target recognition by a homophilic interaction of connectin cell adhesion molecules in DrosophilaA Nose
National Institute for Basic Biology, Myodaiji cho, Ohazaki, Japan
Development 124:1433-41. 1997..Furthermore, the ectopic synapse formation was dependent on the endogenous CON expression on the SNa motoneurons. These results show that CON can function as an attractive and homophilic target recognition molecule in vivo...- Regional specification of muscle progenitors in Drosophila: the role of the msh homeobox geneA Nose
National Institute for Basic Biology, Okazaki, Japan
Development 125:215-23. 1998..These results suggest that msh plays a role in regional specification of muscle progenitors/founders... - The role of the msh homeobox gene during Drosophila neurogenesis: implication for the dorsoventral specification of the neuroectodermT Isshiki
National Institute for Basic Biology, Okazaki, Japan
Development 124:3099-109. 1997.... - Functional dissection of drosophila capricious: its novel roles in neuronal pathfinding and selective synapse formationH Taniguchi
National Institute for Basic Biology, Myodaiji cho, Okazaki 444 8585, Japan
J Neurobiol 42:104-16. 2000..The requirement of the intracellular domain for the function of muscularly expressed CAPS suggests the presence of a signaling event within muscle cells that is essential for selective synapse formation... - Drosophila synapse formation: regulation by transmembrane protein with Leu-rich repeats, CAPRICIOUSE Shishido
National Institute for Basic Biology, Myodaiji cho, Okazaki 444 8585, Japan
Science 280:2118-21. 1998..Loss-of-function and ectopic expression of caps alter the target specificity of muscle 12 motorneurons, indicating a role for caps in selective synapse formation... - Mindin/F-spondin family: novel ECM proteins expressed in the zebrafish embryonic axisS Higashijima
National Institute for Basic Biology, Aichi, Japan
Dev Biol 192:211-27. 1997..In summary, our study has defined a novel gene family of ECM molecules in the vertebrate, all of which may potentially be involved in development of the midline structure... - M-spondin, a novel ECM protein highly homologous to vertebrate F-spondin, is localized at the muscle attachment sites in the Drosophila embryoT Umemiya
National Institute for Basic Biology, Myodaiji cho, Okazaki, Japan
Dev Biol 186:165-76. 1997..We propose that M-spondin, although its function is redundant, is a component of the ECM and mediates mechanical linkage between the muscles and apodemes... - F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neuronsY Feinstein
Department of Anatomy and Cell Biology, The Hebrew University Hadassah Medical School, Jerusalem, PO Box 12272, 91120 Israel
Development 126:3637-48. 1999..We have also demonstrated that the two proteins bind to a putative receptor(s) expressed on both hippocampal and sensory neurons... - Developmental stage-dependent modulation of synapses by postsynaptic expression of activated calcium/calmodulin-dependent protein kinase IIT Morimoto-Tanifuji
Department of Physics, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyoku, Tokyo 113 0033, Japan
Neuroscience 128:797-806. 2004..This suggests the interesting possibility that at certain developmental stages only, modification of synapses on one target cell can influence the synapses on another target cell innervated by the same neurons... - Development of neuromuscular specificity in DrosophilaA Nose
Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley 94720
Cold Spring Harb Symp Quant Biol 57:441-9. 1992 - Synaptic components necessary for retrograde signaling triggered by calcium/calmodulin-dependent protein kinase II during synaptogenesisH Kazama
Department of Physics, Graduate School of Science, University of Tokyo 7 3 1 Hongo, Bunkyoku, Tokyo 113 0033, Japan
Neuroscience 145:1007-15. 2007..These results highlight a novel function of FasII as well as DLG, and more broadly, illustrate that prime synaptic components are necessary for transferring target-derived signals to presynaptic cells at a certain developing synapse... - Ectopic expression of connectin reveals a repulsive function during growth cone guidance and synapse formationA Nose
Howard Hughes Medical Institute, Division of Molecular and Cell Biology, University of California, Berkeley 94720
Neuron 13:525-39. 1994..Moreover, SNb synapse formation is prevented by Connectin expression on ventral muscles. These results reveal a repulsive function for Connectin during motoneuron growth cone guidance and synapse formation... - Connectin: a homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in DrosophilaA Nose
Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley 94720
Cell 70:553-67. 1992..During synapse formation, the protein localizes to synaptic sites; afterward, it largely disappears. Thus, connectin is a novel cell adhesion molecule whose expression suggests a role in target recognition... - Neural cadherin: role in selective cell-cell adhesionS Miyatani
Department of Biophysics, Faculty of Science, Kyoto University, Japan
Science 245:631-5. 1989..The results indicate that each cadherin type confers distinct adhesive specificities on different cells, and also that the specificity of N-cadherin is conserved between mammalian and avian cells... - Innervation and activity dependent dynamics of postsynaptic oxidative metabolismH Kazama
Department of Physics, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Neuroscience 152:40-9. 2008..Our results suggest that flavoprotein autofluorescence imaging should allow us to begin assessing the progress of synapse formation from a metabolic perspective... - A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryosA Nose
J Cell Biol 103:2649-58. 1986..These results suggested that differential expression of multiple classes of cadherins play a role in implantation and morphogenesis of embryos by providing cells with heterogenous adhesive specificity... - Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesisY Hirai
Biomaterial Research Institute, Yokohama, Japan
Development 105:271-7. 1989..These results suggest that cadherins present in epidermal cells are involved not only in maintaining the arrangement of these cells but also in inducing dermal condensation... - Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene familyK Hatta
Department of Biophysics, Faculty of Science, Kyoto University, Japan
J Cell Biol 106:873-81. 1988..The results showed that these molecules contain common amino acid sequences throughout their entire length, which confirms our hypothesis that cadherins make a gene family... - Postsynaptic activation of calcium/calmodulin-dependent protein kinase II promotes coordinated pre- and postsynaptic maturation of Drosophila neuromuscular junctionsH Kazama
Department of Physics, Graduate School of Science, University of Tokyo, 7 3 1 Hongo, Bunkyoku, Tokyo 113 0033, Japan
Neuroscience 117:615-25. 2003..These results suggest two significant functions of postsynaptic CaMKII in synaptogenesis-retrograde modulation of presynaptic properties and coordinated regulation of pre- and postsynaptic maturation... - Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion moleculesA Nose
Department of Biophysics, Faculty of Science, Kyoto University, Japan
EMBO J 6:3655-61. 1987..These results provide evidence for our hypothesis that cadherins constitute a gene family... - Effect of Bifidobacterium bifidum fermented milk on Helicobacter pylori and serum pepsinogen levels in humansK Miki
Faculty of Medicine, Toho University, Ota ku, Tokyo 143 8540, Japan
J Dairy Sci 90:2630-40. 2007..These results indicate that BF-1 fermented milk may affect H. pylori infection or its activity, gastric mucosal situation, and the emergence of upper gastrointestinal symptoms... - Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesisY Hirai
Biomaterial Research Institute, Yokohama, Japan
Development 105:263-70. 1989..These results suggest that E- and P-cadherin have a synergistic role in the organization of epithelial cells in lung morphogenesis...