Research Topics
| Kenji UnoSummaryAffiliation: Nara Medical University Country: Japan Publications
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Detail Information
Publications
Fatal cytomegalovirus-associated adrenal insufficiency in an AIDS patient receiving corticosteroid therapyKenji Uno
Center for Infectious Diseases, Nara Medical University, Nara, Japan
Intern Med 46:617-20. 2007..It is important to be aware that grave adrenal failure due to CMV infection can develop even under steroid therapy...- Macrolide resistance of Streptococcus pneumoniae isolated during long-term macrolide therapy: difference between erythromycin and clarithromycinKei Kasahara
Second Department of Internal Medicine, Nara Medical University, 840 Shijo Cho, Kashihara, Nara, 634 8522, Japan
J Infect Chemother 11:112-4. 2005..7%). No increase in the rate of penicillin resistance was observed in either group. The macrolide resistance profiles of microorganisms may be influenced differently according to differences in the kind of macrolide antibiotics used... - [Questionnaire on prevalence of methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae and sensitivity of Pseudomonas aeruginosa in 2004 in Kinki District]Kei Kasahara
Center for Infectious Diseases, Nara Medical University
Kansenshogaku Zasshi 81:309-11. 2007 - Clonal dissemination of macrolide-resistant and penicillin-susceptible serotype 3 and penicillin-resistant Taiwan 19F-14 and 23F-15 Streptococcus pneumoniae isolates in Japan: a pilot surveillance studyKei Kasahara
Second Department of Internal Medicine, Nara Medical University, 840 Shijo Cho, Kashihara City, Nara 634 8522, Japan
J Clin Microbiol 43:1640-5. 2005..Based on the results of our pilot study performed in a single institution, it is likely that international antibiotic-resistant clones have already spread in Japan; therefore, a nationwide surveillance study should be urgently conducted... - [A case of acute renal failure involving high amounts of tenofovir after HAART start]Eiichiro Yoshimoto
Center for Infectious Diseases, Nara Medical University
Kansenshogaku Zasshi 82:650-3. 2008..TDF taken together with lopinavir may increase the plasma concentration of TDF or other medications that could worsen renal function. It should also be noted that renal dysfunction is a potential complication in the elderly... - Longterm azithromycin therapy for three patients with chronic lower respiratory tract infectionsKei Kasahara
Second Department of Internal Medicine, Nara Medical University, 840 Shijo Cho, Kashihara, Nara, Japan
J Infect Chemother 10:42-5. 2004.... - Amphotericin B-induced nephrogenic diabetes insipidus in a case of cryptococcemiaYukio Fujita
Second Department of Internal Medicine, Nara Medical University, Japan
Intern Med 44:458-61. 2005..This complication is usually reversible, and vigorous water and potassium replacement may allow completion of treatment by amphotericin B, though careful monitoring of body water balance and renal function is of importance... - [Idiopathic esophageal ulcer related to the diagnosis of HIV infection]Mitsuru Konishi
Center for Infectious Diseases, Nara Medical University
Nippon Naika Gakkai Zasshi 95:2539-41. 2006 - [Case of Scedosporium apiospermum cutaneous soft tissue infection treated with voriconazole]Mitsuru Konishi
Center for Infectious Diseases, Department of General Medicine, Nara Medical University
Kansenshogaku Zasshi 82:82-5. 2008..Because VRCZ-induced liver dysfunction was reported significantly associated with plasma level, we treated this case safely by administering VRCZ while measuring the plasma concentration... - [A case of pulmonary Mycobacterium gordonae infection progressed for no therapy]Mitsuru Konishi
Center for Infectious Diseases, Nara Medical University
Nihon Kokyuki Gakkai Zasshi 45:436-40. 2007..Our case also probably was considered to be a primary type pulmonary nontuberculous infection because of her clinical course. In addition, we recognized that pulmonary M. gordonae infection also worsens without the therapy... - Aerosolized pentamidine prophylaxis against AIDS-related Pneumocystis carinii pneumonia and its short- and long-term effects on pulmonary function in the JapaneseMitsuru Konishi
Second Department of Internal Medicine, Nara Medical University, Japan
J Infect Chemother 9:178-82. 2003.... - Evaluation of diagnostic methods for Candida albicans translocation in a mouse model: seminested polymerase chain reaction, blood culture, and serological assaysKenji Uno
Center for Infectious Diseases, Nara Medical University School of Medicine, Kashihara, Nara 634 8521, Japan
J Infect Chemother 13:196-203. 2007..Therefore, the combination of the serological assays and the snPCR seems to be valuable for the early diagnosis of systemic C. albicans infection... - [Management of immune reconstitution inflammatory syndrome]Mitsuru Konishi
Center for Infectious Diseases, Nara Medical University
Nihon Rinsho 68:508-11. 2010..Management of IRIS consists of appropriate treatment for the diseases of IRIS, control of the excessive inflammation (NSAIDs or corticosteroids), and interrupting ART... - Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivityKenji Uno
Division of Molecular Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan
Science 312:1656-9. 2006..Furthermore, an antidiabetic thiazolidinedione, a PPARg agonist, enhanced this pathway. This neuronal pathway from the liver may function to protect against metabolic perturbation induced by excessive energy storage... - Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesityYasushi Ishigaki
Division of Advanced and Therapeutics for Metabolic Diseases, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
Diabetes 54:322-32. 2005..Thus, enhanced UCP expression in the liver is a new potential therapeutic target for the metabolic syndrome... - Impact of plasma oxidized low-density lipoprotein removal on atherosclerosisYasushi Ishigaki
Division of Molecular Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan
Circulation 118:75-83. 2008..In addition, oxidized LDL (oxLDL) is suggested to play roles in the formation and progression of atherosclerosis. However, whether lowering oxLDL alone, rather than total LDL, affects atherogenesis remains unclear... - Constitutively active PDX1 induced efficient insulin production in adult murine liverJunta Imai
Division of Molecular Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Japan
Biochem Biophys Res Commun 326:402-9. 2005..Thus, transient expression of an active mutant of PDX1 in the liver induced sustained PDX1 and insulin expressions without loss of hepatocytic function...