Research Topics
Genomes and GenesSpecies | Koji HattoriSummaryAffiliation: Nara Medical University Country: Japan Publications
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Publications
Measurement of the mechanical condition of articular cartilage with an ultrasonic probe: quantitative evaluation using wavelet transformationKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, 840, Shijyo cho, Kashihara, Nara 634 8522, Japan
Clin Biomech (Bristol, Avon) 18:553-7. 2003..To develop a new diagnostic technology to evaluate articular cartilage quantitatively by introducing an ultrasonic probe into the knee joint under arthroscopy and analyzing the A-mode echogram by means of wavelet transformation...
Bio-artificial periosteum for severe open fracture--an experimental study of osteogenic cell/collagen sponge composite as a bio-artificial periosteumKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
Biomed Mater Eng 15:127-36. 2005..We conclude that by using the bio-artificial periosteum, the fracture site benefited from an improved osteogenic environment. These results indicate that a clinical trial to further evaluate this technique should be conducted...
Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffoldKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan
Arthritis Res Ther 7:R552-9. 2005..Therefore, ultrasonic evaluation using a wavelet map can support the evaluation of tissue-engineered cartilage using cell/scaffold complexes...
Spectrocolorimetric assessment of cartilage plugs after autologous osteochondral grafting: correlations between color indices and histological findings in a rabbit modelKoji Hattori
Department of DAIWA HOUSE Indoor Environmental Medicine, Nara Medical University, Kashihara, Nara, Japan
Arthritis Res Ther 9:R88. 2007..Therefore, spectrocolorimetry may contribute to orthopedics, rheumatology and related research in arthritis, and arthroscopic use of this method may potentially be preferable for in vivo assessment...
Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritisKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, Japan
Arthritis Res Ther 7:R38-46. 2005..There was a significant correlation between the maximum magnitude and the aggregate modulus. The evaluation system therefore successfully detected microscopic changes in degenerated cartilage with the use of collagen-induced OA...
Which cartilage is regenerated, hyaline cartilage or fibrocartilage? Non-invasive ultrasonic evaluation of tissue-engineered cartilageK Hattori
Department of Orthopaedic Surgery, Nara Medical University, 840, Shijyo cho, Kashihara, Nara, 634 8522, Japan
Rheumatology (Oxford) 43:1106-8. 2004..To investigate ultrasonic evaluation methods for detecting whether the repair tissue is hyaline cartilage or fibrocartilage in new cartilage regeneration therapy...
Differential acoustic properties of early cartilage lesions in living human knee and ankle jointsKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, Japan
Arthritis Rheum 52:3125-31. 2005..The current study was undertaken to determine whether the acoustic properties of living human cartilage differ between knee and ankle joints...
Quantitative arthroscopic ultrasound evaluation of living human cartilageKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, 840, Shijyo cho, Kashihara, Nara 634 8522, Japan
Clin Biomech (Bristol, Avon) 19:213-6. 2004....
Quantitative ultrasound can assess living human cartilageKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, Shijyo-cho 840, Kashihara, Nara 634-8522, Japan
J Bone Joint Surg Am 88:201-12. 2006
Can ultrasound predict histological findings in regenerated cartilage?K Hattori
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijyo cho, Kashihara, Nara 634 8522, Japan
Rheumatology (Oxford) 43:302-5. 2004..To evaluate regenerated articular cartilage quantitatively by introducing an ultrasonic probe into the knee joint under arthroscopy and analysing the A-mode echogram by means of wavelet transformation...
Ultrasound evaluation of cartilage damage in osteochondral lesions of the talar dome and correlation with clinical etiology: a preliminary reportKoji Hattori
Orthopaedic Surgery, Nara Medical University, Kashihara, Nara 634 8522, Japan
Foot Ankle Int 28:208-13. 2007..The current study aimed to determine whether the acoustic properties of living human cartilage during arthroscopy differ between damage from trauma and that from pigmented villonodular synovitis (PVNS)...
Spectrocolorimetric evaluation of repaired articular cartilage after a microfractureKoji Hattori
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, Amagasaki Site, Amagasaki, Hyogo, Japan
BMC Res Notes 1:87. 2008..Objective assessments are required. A spectrocolorimeter was used to evaluate whether intact and repaired cartilage can be quantified...
Novel ultrasonic evaluation of tissue-engineered cartilage for large osteochondral defects--non-invasive judgment of tissue-engineered cartilageKoji Hattori
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara 634 8522, Japan
J Orthop Res 23:1179-83. 2005....
Stimulatory effects of statins on bone marrow-derived mesenchymal stem cells. Study of a new therapeutic agent for fractureMasato Sonobe
Department of Orthopaedic Surgery, Toho University School of Medicine 6-11-1 Omorinishi, Ota-ku, Tokyo 143-8541, Japan
Biomed Mater Eng 15:261-7. 2005..These findings suggest that statins do not increase bone formation in bone marrow-derived mesenchymal stem cells...
Cartilage regeneration using mesenchymal stem cells and a three-dimensional poly-lactic-glycolic acid (PLGA) scaffoldKota Uematsu
Department of Orthopaedic Surgery, Nara Medical University, 840, Shijou cho, Kashihara City, Nara 634 8522, Japan
Biomaterials 26:4273-9. 2005..The structure of the novel PLGA scaffolds provided architectural support for the differentiation of progenitor cells and demonstrated successful induction of in vivo chondrogenesis...
Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cellsShinji Isomoto
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijyo cho, Kashihara, Nara, 634 8522, Japan
J Orthop Sci 12:83-8. 2007..This study assessed the effects of immunosuppressant drugs on osteogenic differentiation of mesenchymal stem cells and analyzed the manner in which immunosuppressant drugs modulate the osteogenic effect of dexamethasone...
A pilot feasibility study for ultrasound evaluation of living human wrist cartilage: site-specific differences in acoustic propertiesKoji Shigematsu
Department of Orthopaedic Surgery and Daiwa House Indoor Environmental Medicine, Nara Medical University, Nara, Japan
J Hand Surg Am 34:34-9. 2009..The purpose of this study was to evaluate and quantify the acoustic properties of wrist articular cartilage quantitatively using a new acoustic probe under arthroscopic observation...
[Articular cartilage regeneration using scaffold]Yoshiyuki Ishimoto
Nara Medical University, Department of Orthopaedic Surgery
Clin Calcium 18:1775-80. 2008..In a case of chondrocyte transplantation to cartilage defect site, the use of proper scaffold is important. Currently, collagen gel or PLGA is used widely as a scaffold...
Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYCTetsuhiro Aoki
Tissue Engineering Research Group, Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, Amagasaki, Hyogo, Japan
Tissue Eng Part A 16:2197-206. 2010..Further, the colonies were able to differentiate into the three germ layers both in vitro and in vivo. These results show that human iPSCs can be generated by the transduction of three factors (OCT3/4, SOX2, and KLF4) into hASCs...
The report of the cartilage regeneration using total joint regeneration system (internal-fixator type)Hideyuki Aoki
Department of Orthopaedic Surgery, School of Medicine, Toho University, 6-11-1 Omorinishi, Ota-ku, Tokyo 143-8541, Japan
Biomed Mater Eng 13:411-7. 2003..This paper introduces the basic concepts of total joint regeneration and reports the results of the first animal experiment using an internal-fixator device using rabbits and a dog...
High tibial osteotomy that does not cause recurrence of varus deformity for medial gonarthrosisTakashi Habata
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo, Kashihara, Nara 634 8522, Japan
Knee Surg Sports Traumatol Arthrosc 14:962-7. 2006..The clinical results were not poor after slightly overcorrected osteotomy was performed. Since overcorrection tended to occur, when the preoperative lateral tibial thrust was severe, HTO is not a good indication for such cases...
Culture of chondrocytes in fibroin-hydrogel spongeHideyuki Aoki
Department of Orthopaedic Surgery, School of Medicine, Toho University, 6-11-1 Omorinishi, Ota-ku, Tokyo 143-8541, Japan
Biomed Mater Eng 13:309-16. 2003..Thus, the chondrocytes proliferated in the fibroin sponge without losing their differentiated phenotype. It is possible that culture environment in the fibroin sponge was suitable for chondrocytes regeneration...
Raloxifene: its ossification-promoting effect on female mesenchymal stem cellsHiroaki Matsumori
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, Japan
J Orthop Sci 14:640-5. 2009....
Autofluorescence assessment of extracellular matrices of a cartilage-like tissue construct using a fluorescent image analyserYusuke Hagiwara
Department of Orthopaedic Surgery, Nippon Medical School Graduate School of Medicine, Bunkyo ku, Tokyo, Japan
J Tissue Eng Regen Med 5:163-8. 2011..Therefore, the image analyser can be used to judge the success or failure of the in vitro culture process of TCL construct without a biopsy. Copyright © 2010 John Wiley & Sons, Ltd...
A comparative study of induced pluripotent stem cells generated from frozen, stocked bone marrow- and adipose tissue-derived mesenchymal stem cellsHiroe Ohnishi
Tissue Engineering Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology AIST, Amagasaki Site, Amagasaki, Hyogo, Japan
J Tissue Eng Regen Med 6:261-71. 2012..Copyright © 2011 John Wiley & Sons, Ltd...
Proximal spherical metatarsal osteotomy for the foot with severe hallux valgusYasuhito Tanaka
Nara Medical University, Department of Orthopaedic Surgery, Department of Orthopaedic Surgery Nara Medical University, Kashihara, Nara 634 8522, Japan
Foot Ankle Int 29:1025-30. 2008..To investigate the limitations of this procedure for feet with severe hallux valgus, a followup study was performed on patients with preoperative hallux valgus angles greater than or equal to 40 degrees...
Mechanical effects of surgical procedures on osteochondral grafts elucidated by osmotic loading and real-time ultrasoundKoji Hattori
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, 3 11 46, Nakoji, Amagasaki, Hyogo 661 0974, Japan
Arthritis Res Ther 11:R134. 2009..The present study aimed to investigate the mechanical effects of osteochondral plug implantation using osmotic loading and real-time ultrasound...
Sclerotherapy for intractable ganglion cyst of the halluxYasuhito Tanaka
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, 634 8522, Japan
Foot Ankle Int 30:128-32. 2009..We devised a method of sclerotherapy using OK432. The present study comprised a retrospective followup of sclerotherapy outcomes...
[Progress of research in osteoarthritis. Tissue engineering therapy for osteoarthritis]Koji Hattori
Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology
Clin Calcium 19:1621-8. 2009..In this paper, we introduce the trend of the approaches for cartilage defects and refer to the possibility for the treatments of osteoarthritic patients...
Osteochondritis dissecans of the knee: long-term results of excision of the osteochondral fragmentKota Uematsu
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo, Kashihara, Nara 634 8522, Japan
Knee 12:205-8. 2005..The study suggests that clinical and radiological results are good following removal of the osteochondral loose fragments are excised...
Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 monthsShigeyuki Wakitani
Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Japan
J Tissue Eng Regen Med 5:146-50. 2011..Neither tumours nor infections were observed between 5 and 137 (mean 75) months of follow-up. Autologous BMSC transplantation is a safe procedure and will be widely used around the world...
Long-term clinical and radiographic follow-up of total resection for discoid lateral meniscusTakashi Habata
Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Japan
Arthroscopy 22:1339-43. 2006....
Rapid preparation of fresh frozen tissue-engineered bone sections for histological, histomorphological and histochemical analysesMika Tadokoro
National Institute of Advanced Industrial Science and Technology, Amagasaki Site, 3-11-46, Wakaouji, Amagasaki, Hyogo 661-0974, Japan
Biomed Mater Eng 16:405-13. 2006..It is expected that this method will become a powerful tool in tissue-engineering of hard tissues...
Treatment of Kienböck's disease with cultured stem cell-seeded hybrid tendon roll interposition arthroplasty: experimental studyKoji Shigematsu
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan
J Orthop Sci 11:198-203. 2006..CONCLUSIONS: Radiological and histological examinations proved that it is possible to make new hybrid tendon rolls using this method, as osteogenesis in the center and cartilage matrix in the peripheral of the tendon roll were revealed...
Clinical features of the posterior horn tear in the medial meniscusT Habata
Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo, Kashihara, 634 8522 Nara, Japan
Arch Orthop Trauma Surg 124:642-5. 2004..The purpose of this paper is to demonstrate the key points for diagnosis through examination of the clinical features of this tear...
Bone morphogenetic protein-2 in biodegradable gelatin and ?-tricalcium phosphate sponges enhances the in vivo bone-forming capability of bone marrow mesenchymal stem cellsMika Tadokoro
Health Research Institute, National Institute of Advanced Industrial Science and Technology AIST, 3 11 46 Nakoji, Amagasaki, Hyogo 661 0974, Japan
J Tissue Eng Regen Med 6:253-60. 2012..Copyright © 2011 John Wiley & Sons, Ltd...
Induction of pluripotent stem cells from human third molar mesenchymal stromal cellsYasuaki Oda
Tissue Engineering Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, Hyogo 661 0974, Japan
J Biol Chem 285:29270-8. 2010..Because human third molars are discarded as clinical waste, our data indicate that clonally expanded MSCs derived from human third molars are a valuable cell source for the generation of iPS cells...
Investigation of segmental carpal tunnel pressure in patients with idiopathic carpal tunnel syndrome--is it necessary to release the distal aponeurotic portion of the flexor retinaculum in endoscopic carpal tunnel release surgery?Keiichi Murata
Department of Orthopaedic Surgery, School of Medicine, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
Hand Surg 12:205-9. 2007....
Microenvironment array chip for cell culture environment screeningKoji Hattori
Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology, Central 5th, 1 1 1 Higashi, Tsukuba Ibaraki 305 8565, Japan
Lab Chip 11:212-4. 2011..We have developed a microarray of cell culture environments composed of a combination of soluble factors and extracellular matrices for screening of cell culture environment...
Spectrocolorimetric evaluation of human articular cartilageY Ishimoto
Department of Orthopedic Surgery, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8522, Japan
Osteoarthritis Cartilage 17:1204-8. 2009..The aim of this study was to investigate whether human articular cartilage can be quantitatively evaluated using a spectrocolorimeter...
Contralateral meningeal artery supply of paramedian meningiomasKoji Hattori
Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
Surg Neurol 64:242-8; discussion 248. 2005..We attribute such difficulties to meningeal artery blood supply from the contralateral side. We retrospectively studied feeding arteries from both sides in case of paramedian meningioma in terms of patient and tumor characteristics...
Endovascular treatment strategy for direct carotid-cavernous fistulas resulting from rupture of intracavernous carotid aneurysmsNozomu Kobayashi
Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
AJNR Am J Neuroradiol 24:1789-96. 2003..CONCLUSION: Although other techniques using a transvenous approach and/or detachable coils may also be useful, embolization with detachable balloons should be a safe and effective method to immediately occlude the fistula...
Off-pump coronary artery bypass surgery in a renal transplant patientKoji Hattori
Department of Cardiovascular Surgery, Fujita Health University, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi 470 1192, Japan
Jpn J Thorac Cardiovasc Surg 54:532-4. 2006..On postoperative day 2, his usual immunosuppressive agents were resumed as per his normal dosage. He recovered uneventfully and is well without angina pectoris and renal complication 1 year after the operation...
Evaluation of the effect of collagen network degradation on the frictional characteristics of articular cartilage using a simultaneous analysis of the contact conditionMarco Hiroshi Naka
Laboratory of Nano biomechanisms, Institute for Frontier Medical Sciences, Kyoto University, 53 Shogoin Kyoto 606 8507, Japan
Clin Biomech (Bristol, Avon) 20:1111-8. 2005..In this work, a technique based on the evanescent waves is used for the evaluation of contact condition during friction tests...
Evaluation of the superficial characteristics of articular cartilage using evanescent waves in the friction tests with intermittent sliding and loadingMarco Hiroshi Naka
Laboratory of Nano biomechanisms, Institute for Frontier Medical Sciences, Kyoto University, 53 Shogoin Kawahara cho, Kyoto 606 8507, Japan
J Biomech 39:2164-70. 2006..Results indicated that the increase in the water content at the articular surface and the rehydration ability of articular cartilage after unloading could be responsible for the maintenance of friction in low levels...
Rectus abdominis myocutaneous flap after unsuccessful delayed sternal closureToshihiko Shibata
Department of Cardiovascular Surgery, Osaka City University Medical School, Osaka, Japan
Ann Thorac Surg 76:956-8. 2003..This alternative method of chest reconstruction is useful in patients after an unsuccessful delayed sternal closure...
