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Genomes and Genes | Y MuroSummaryAffiliation: Nagoya University Country: Japan Publications
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Publications
Antinuclear antibodiesYoshinao Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology Nagoya University Graduate School of Medicine 65 Tsurumai cho, Showa ku Nagoya 466 8550 Japan
Autoimmunity 38:3-9. 2005..In this text, several representative patterns of fluorescence are reviewed and some pitfalls for application of the results to the clinical field are mentioned...- High concomitance of disease marker autoantibodies in anti-DFS70/LEDGF autoantibody-positive patients with autoimmune rheumatic diseaseY Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
Lupus 17:171-6. 2008..Recognizing dense fine speckle patterns in anti-nuclear antibodies tests is, thus, very important for analysis of laboratory results in rheumatology clinics... - Disappearance of anti-MDA-5 autoantibodies in clinically amyopathic DM/interstitial lung disease during disease remissionYoshinao Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Rheumatology (Oxford) 51:800-4. 2012..Serial monitoring at short intervals is required to evaluate whether anti-MDA-5 antibody levels correlate with ADM disease activity... - Epidemiologic study of clinically amyopathic dermatomyositis and anti-melanoma differentiation-associated gene 5 antibodies in central JapanYoshinao Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Arthritis Res Ther 13:R214. 2011..The present study aims to assess the growing prevalence of CADM and the geographical incidence of anti-MDA-5-positive patients... - Evaluation of anti-ribosomal P protein immunoassay in Japanese patients with connective tissue diseases: comparison with an indirect immunofluorescence assayY Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Scand J Rheumatol 38:460-3. 2009.... - An evaluation of the efficacy of the toe brachial index measuring vascular involvement in systemic sclerosis and other connective tissue diseasesY Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Clin Exp Rheumatol 27:26-31. 2009..We sought to evaluate the efficacy of ABI and TBI as an objective, non-invasive assessment of vascular involvement in patients with systemic sclerosis (SSc) and to investigate the clinical significance of TBI in SSc... - Scoring of reflux symptoms associated with scleroderma and the usefulness of rabeprazoleY Muro
Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Clin Exp Rheumatol 27:15-21. 2009..The present study used a GERD-specific questionnaire to assess the symptoms of GERD in SSc patients, and examine the effectiveness of rabeprazole (RPZ) for treating the symptoms of GERD... - HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune diseaseYoshinao Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Showa Ku, Japan
J Autoimmun 26:252-7. 2006..HLA class II genes influence the production of anti-DFS70 antibodies among individuals with various clinical manifestations... - Autoantibodies in atopic dermatitisY Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Graduate School of Medicine, Nagoya University, 65 Tsurumai Cho, Showa Ku, 466 8550, Nagoya, Japan
J Dermatol Sci 25:171-8. 2001..In addition, p80-coilin in nuclear coiled bodies is also targetted. Several lines of evidence suggest that a subset of atopic dermatitis may be associated with an autoimmune response... - Low frequency of autoantibodies against Ki-67 antigen in Japanese patients with systemic autoimmune diseasesY Muro
Department of Dermatology, Nagoya University School of Medicine, Nagoya, Japan
J Autoimmun 10:499-503. 1997.... - Autoepitopes on autoantigen centromere protein-A (CENP-A) are restricted to the N-terminal region, which has no homology with histone H3Y Muro
Department of Dermatology, Nagoya University School of Medicine, Nagoya, Japan
Clin Exp Immunol 120:218-23. 2000.... - Anti-cyclic citrullinated peptide antibody in systemic sclerosisY Morita
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Clin Exp Rheumatol 26:542-7. 2008.... - cDNA cloning of a novel autoantigen targeted by a minor subset of anti-centromere antibodiesY Muro
Department of Dermatology, Nagoya University School of Medicine, Japan
Clin Exp Immunol 111:372-6. 1998.... - A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activityK Yoda
Department of Molecular Biology, School of Science, Nagoya University, Japan
J Cell Biol 119:1413-27. 1992..Thus, CENP-B may organize a higher order structure in the centromere by juxtaposing two CENP-B boxes in the alphoid DNA repeat through both the DNA-protein and protein-protein interactions... - Dymple, a novel dynamin-like high molecular weight GTPase lacking a proline-rich carboxyl-terminal domain in mammalian cellsT Kamimoto
Department of Anatomy, Nagoya University School of Medicine, Showa Ku, Nagoya, Japan
J Biol Chem 273:1044-51. 1998..Our findings suggest that dymple may be the first example of such a subfamily in mammalian cells other than dynamin itself, although its precise role and membrane localization remain to be resolved... - Results of the Health Assessment Questionnaire for Japanese patients with systemic sclerosis--measuring functional impairment in systemic sclerosis versus other connective tissue diseasesY Morita
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, Nagoya, Japan
Clin Exp Rheumatol 25:367-72. 2007..To evaluate the physical functional impairment in patients with systemic sclerosis (SSc) using the Health Assessment Questionnaire (HAQ) and to estimate the correlation of HAQ scores with the severity of SSc... - Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic conditionTakuya Takeichi
Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
J Invest Dermatol 130:2760-7. 2010..These findings are compatible with the expression pattern in psoriatic tissues. Taken together, these results strongly suggest that ectopic expression of LEDGF/DFS70 in KCs could be involved in the pathology of psoriasis vulgaris... - Autoantibody to thioredoxin reductase in an ovarian cancer patientY Muro
Department of Dermatology, Nagoya University School of Medicine
Biochem Biophys Res Commun 242:267-71. 1998..Since dysregulation of TR in cancer cells is considered to be involved in some redox states of tumorigenesis, the observed antibody response in this patient could have arisen due to immunoreaction to the abnormally regulated protein... - The unfolded protein response is activated in differentiating epidermal keratinocytesKazumitsu Sugiura
Department of Dermatology, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
J Invest Dermatol 129:2126-35. 2009..Taken together, our findings strongly suggest that the UPR is activated during normal epidermal KC differentiation and induces C/EBPbeta, KLF4, and ABCA12 mRNAs... - Anti-DFS70 antibodies in 597 healthy hospital workersAkihiro Watanabe
Nagoya University Graduate School of Medicine, Nagoya, Japan
Arthritis Rheum 50:892-900. 2004..In addition, this test defines a subpopulation of healthy people in whom long-term followup might reveal health-related implications of this finding, since anti-DFS70 antibodies have been shown to be associated with some illnesses... - LEDGF/DFS70, a major autoantigen of atopic dermatitis, is a component of keratohyalin granulesKazumitsu Sugiura
Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Japan
J Invest Dermatol 127:75-80. 2007..Once in the cytoplasm, LEDGF/DFS70 accumulates in the KGs in the granular layer. Finally, LEDGF/DFS70, a "nuclear" autoantigen in AD, may play a functional role in the KGs... - Expression cloning and intracellular localization of a human ZF5 homologueK Sugiura
Department of Anatomy, Nagoya University School of Medicine, Showa Ku, Japan
Biochim Biophys Acta 1352:23-6. 1997..3% identity). Immunofluorescence studies revealed that HA-tagged hZF5 transiently expressed in COS-7 cells showed the nuclear dot pattern in the BTB/POZ domain-dependent manner... - Anti-p80 coilin autoantibodies react with a conserved epitope and are associated with anti-DFS70/LEDGF autoantibodiesNaoya Goto
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan
J Autoimmun 26:42-51. 2006..We conclude that the presence of anti-p80 coilin autoantibodies is not associated with any particular clinical syndromes nor is it diagnostic of any conditions... - Autoantibodies to DFS70/LEDGF are increased in alopecia areata patientsMiyako Okamoto
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
J Autoimmun 23:257-66. 2004..The elevated anti-DFS70 antibodies in alopecia patients and the localization of the DFS70 in the ORS suggest that autoantibodies against the DFS70 are related to the etiology in a certain population of AA... - Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domainYasushi Ogawa
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa Ku, Nagoya 466 8550, Japan
J Autoimmun 23:221-31. 2004..We propose that anti-DFS70 antibody may be a natural autoantibody, which might modify or reflect the inflammatory process of various disorders... - CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosisAkiko Saito
Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Turumai cho Showa ku, Nagoya, 466 8550, Japan
J Rheumatol 36:781-6. 2009..The CENP-O protein is a component of the ICEN that localizes at the centromere throughout the cell cycle. We investigated whether CENP-O is also targeted by sera from patients with systemic autoimmune diseases... - Anti-ribosomal-P antibodies in a Sjögren syndrome patient associated with lupus erythematosusYoshinao Muro
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
J Dermatol 31:811-4. 2004..Although autoantibodies to ribosomal-P proteins appear mainly in patients with systemic lupus erythematosus (SLE), a diagnosis of SLE in this patient could not be supported... - Anti-SS-A/Ro antibody determination by indirect immunofluorescence and comparison of different methods of anti-nuclear antibody screening: evaluation of the utility of HEp-2 cells transfected with the 60 kDa SS-A/Ro as a substrateNoriyo Tanaka
Division of Connective Tissue Disease and Autoimmunity, Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
Mod Rheumatol 18:585-92. 2008....