Research Topics
Species | Hiroshi KitohSummaryAffiliation: Nagoya University Country: Japan Publications
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Detail Information
Publications
A histological and ultrastructural study of the iliac crest apophysis in Legg-Calve-Perthes diseaseHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop 28:435-9. 2008..In this study, the biopsy specimens of the iliac crest apophysis from LCPD patients were examined histologically and ultrastructurally to determine preexisting generalized abnormalities of endochondral ossification...- Sagittal spinal alignment in patients with Legg-Calve-Perthes diseaseHiroshi Kitoh
Department of Orthopedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
Pediatr Int 49:612-7. 2007..In the present study sagittal spinal alignment of the patients with LCPD was analyzed to examine associated spinal involvement... - Distraction osteogenesis of the lower extremity in patients with achondroplasia/hypochondroplasia treated with transplantation of culture-expanded bone marrow cells and platelet-rich plasmaHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop 27:629-34. 2007.... - Spondylometaphyseal dysplasia with cone-rod dystrophyHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Japan
Am J Med Genet A 155:845-9. 2011..Skeletal manifestations in addition to comprehensive ophthalmologic examinations were described in this patient who had been followed from infancy to 16 years of age... - Predictive factors for unsuccessful treatment of developmental dysplasia of the hip by the Pavlik harnessHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop 29:552-7. 2009..Predictive factors for unsuccessful Pavlik harness treatment should be determined for appropriate indication of the treatment and prevention of AVN... - Transplantation of marrow-derived mesenchymal stem cells and platelet-rich plasma during distraction osteogenesis--a preliminary result of three casesHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Showa Ku, Nagoya, Aichi 466 8550, Japan
Bone 35:892-8. 2004.... - Radiographic analysis of movements of the acetabulum and the femoral head after Salter innominate osteotomyHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop 29:879-84. 2009..Salter innominate osteotomy (SIO) is widely used to improve the coverage of the femoral head in dysplastic acetabulum, but the geometric change after osteotomy and its effect on the outcome have not been well elucidated... - Differential effects of culture-expanded bone marrow cells on the regeneration of bone between the femoral and the tibial lengtheningsHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop 29:643-9. 2009.... - Transplantation of culture expanded bone marrow cells and platelet rich plasma in distraction osteogenesis of the long bonesHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, Nagoya, Aichi 466 8550, Japan
Bone 40:522-8. 2007..0004) In conclusion, transplantation of BMC and PRP shortened the treatment period and reduced associated complications by accelerating new bone formation in DO... - The effect of recombinant human bone morphogenetic protein-2 on the osteogenic potential of rat mesenchymal stem cells after several passagesHisato Ishikawa
Department of Orthopaedic Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi, 466 8550, Japan
Acta Orthop 78:285-92. 2007..Thus, we analyzed the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the osteogenic potential of rat BMSCs over several passages... - Osteogenic potential of rat mesenchymal stem cells after several passagesFumiaki Sugiura
Department of Orthopaedic Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi 466 8550, Japan
Biochem Biophys Res Commun 316:233-9. 2004..Establishment of the culture conditions that permit the rapid expansion of BMCs while retaining their potential for differentiation will be required for future clinical applications... - Prediction of acetabular development after closed reduction by overhead traction in developmental dysplasia of the hipHiroshi Kitoh
Department of Orthopaedic Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan
J Orthop Sci 11:473-7. 2006..Bilateral DDH and poor acetabular coverage of the uninvolved hip in unilateral DDH were the prognostic factors of unfavorable acetabular development of the dislocated hip... - Home traction in the treatment schedule of overhead traction for developmental dysplasia of the hipTakahiko Kitakoji
Department of Orthopaedic Surgery, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
J Orthop Sci 10:475-9. 2005..A short-term instructive hospitalization period may be useful to reduce the disadvantages of home traction, that is, unreliable performance of traction and increased anxiety of the family... - [Molecular mechanism in the differentiation of chondrocytes]Hiroshi Kitoh
Nagoya University School of Medicine, Department of Orthopaedic Surgery
Clin Calcium 17:493-8. 2007..Here, we summarize the functions of these molecules and their networks for the differentiation and maturation of chondrocytes... - Hyperuricemia cosegregating with osteogenesis imperfecta is associated with a mutation in GPATCH8Hiroshi Kaneko
Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa Ku, Nagoya 466 8550, Japan
Hum Genet 130:671-83. 2011..GPATCH8 is only 5.8 Mbp distant from COL1A1 and encodes a protein harboring an RNA-processing domain and a zinc finger domain, but the molecular functions have not been elucidated to date... - Patellar dislocation in achondroplasiaYuji Takamine
Department of Orthopaedic Surgery, Central Hospital, Aichi Welfare Center for Persons with Developmental Disabilities, Kasugai, Aichi, Japan
J Pediatr Orthop B 17:47-9. 2008..Patellar dislocation for achondroplasia may be caused not only by the abnormalities of soft tissue but also a small groove of patellofemoral joint as a bony malformation... - Chondroblastoma of the femoral neck as a cause of hip synovitisHiroshi Kaneko
Department of Orthopaedic Surgery, Nagoya University, School of Medicine, Nagoya, Aichi, Japan
J Pediatr Orthop B 21:179-82. 2012..Complete relief of pain and an improvement in the range of movement of the hip joint was obtained after surgical resection of the tumor... - Spatial and temporal distribution of growth factors receptors in the callus: implications for improvement of distraction osteogenesisKarolina A Siwicka
Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, Nagoya, Japan
Nagoya J Med Sci 73:117-27. 2011..Rapid decline of growth factors receptors in the fibrous zone may imply its decreasing sensitivity to growth factors and, as a consequence, a declining osteogenic potential... - Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cellsHiroki Tsuchiya
Department of Orthopaedic Surgery, Nagoya University School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi 466 8550, Japan
Biochem Biophys Res Commun 301:338-43. 2003..These results indicated that cell-mediated sox9 gene therapy could be a novel strategy for hyaline cartilage damage... - Deformities of the elbow in achondroplasiaHiroshi Kitoh
Department of Orthopaedic Surgery, School of Medicine, Nagoya University, Aichi, Japan
J Bone Joint Surg Br 84:680-3. 2002..3 degrees). Posterior bowing of the distal humerus is a principal cause of loss of extension of the elbow. Posterior dislocation of the radial head causes further limitation of movement in the more severely affected joints... - Factors related to surgical outcome after posterior decompression and fusion for craniocervical junction lesions associated with osteogenesis imperfectaShiro Imagama
Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai cho Showa ku, Nagoya, Aichi 466 8550, Japan
Eur Spine J 20:S320-5. 2011.... - A recurrent mutation in type II collagen gene causes Legg-Calvé-Perthes disease in a Japanese familyYoshinari Miyamoto
Laboratory for Bone and Joint Diseases, SNP Research Center, RIKEN, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
Hum Genet 121:625-9. 2007..This is the first report of a mutation in hereditary LCPD. COL2A1 mutations may be more common in LCPD patients than currently thought, particularly in familial and/or bilateral cases... - Novel and recurrent mutations clustered in the von Willebrand factor A domain of MATN3 in multiple epiphyseal dysplasiaAkihiko Mabuchi
Laboratory for Bone and Joint Diseases, SNP Research Center, RIKEN, 108 8639 Tokyo, Japan
Hum Mutat 24:439-40. 2004..120-127). Contrary to the previous assumption that the MATN3 mutation in MED is confined to the beta-sheet regions, one novel mutation (p.F105S) is located outside the beta-sheet region, within an alpha-helix region... - Novel types of COMP mutations and genotype-phenotype association in pseudoachondroplasia and multiple epiphyseal dysplasiaAkihiko Mabuchi
Laboratory for Bone and Joint Deseases, SNP Research Center, RIKEN, c o Institute of Medical Science, University of Tokyo, Tokyo, Japan
Hum Genet 112:84-90. 2003..0024). These findings expand the mutation spectrum of the COMP gene and highlight genotype-phenotype relationships, facilitating improved genetic diagnosis and analysis of COMP function in humans... - SHOX nullizygosity and haploinsufficiency in a Japanese family: implication for the development of Turner skeletal featuresTsutomu Ogata
Department of Pediatrics, Keio University School of Medicine, Tokyo 160 8582, Japan
J Clin Endocrinol Metab 87:1390-4. 2002....