J Katada

Summary

Affiliation: Nagasaki University
Country: Japan

Publications

  1. ncbi Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor-knockout mice after myocardial infarction
    Jun Katada
    Pfizer KEIO Research Laboratory, Tokyo, Japan
    Circulation 111:2157-64. 2005
  2. ncbi Significance of cyclooxygenase-2 induced via p38 mitogen-activated protein kinase in mechanical stimulus-induced peritoneal adhesion in mice
    Jun Katada
    KEIO Research Park 2N4, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Pharmacol Exp Ther 313:286-92. 2005
  3. ncbi Significance of vascular endothelial cell growth factor up-regulation mediated via a chymase-angiotensin-dependent pathway during angiogenesis in hamster sponge granulomas
    Jun Katada
    Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, Japan
    J Pharmacol Exp Ther 302:949-56. 2002
  4. ncbi Role of mast cell chymase in angiotensin-induced vascular contraction of hamster cheek pouch microvessels
    J Katada
    Life Science Research Center, Advanced Technology Research Laboratories, Kawasaki, Japan
    Eur J Pharmacol 379:63-72. 1999
  5. ncbi AT(2) receptor-dependent vasodilation is mediated by activation of vascular kinin generation under flow conditions
    Jun Katada
    Department of Pharmacology, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
    Br J Pharmacol 136:484-91. 2002
  6. ncbi Discovery and structure--activity relationship studies of a novel and specific peptide motif, Pro-X-X-X-Asp-X, as a platelet fibrinogen receptor antagonist
    Y Hayashi
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, Kawasaki, Japan
    Bioorg Med Chem 6:355-64. 1998
  7. ncbi Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model
    M Muramatsu
    Department of Pharmacology, Kitasato University School of Medicine, 1 15 1 Kitasato Sagamihara shi, Kanagawa 228 8555, Japan
    J Biol Chem 275:5545-52. 2000
  8. ncbi Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants
    M Majima
    Department of Pharmacology, Kitasato University School of Medicine, Kitasato 1 15 1, Sagamihara, Kanagawa 228 8555, Japan
    Br J Pharmacol 130:641-9. 2000
  9. ncbi GPIIb/IIIa integrin antagonists with the new conformational restriction unit, trisubstituted beta-amino acid derivatives, and a substituted benzamidine structure
    Y Hayashi
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, 3 35 1 Ida, Nakahara ku, Kawasaki 211 0035, Japan
    J Med Chem 41:2345-60. 1998
  10. ncbi Antitumor activity of phenylahistin in vitro and in vivo
    K Kanoh
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, Kawasaki, Japan
    Biosci Biotechnol Biochem 63:1130-3. 1999

Detail Information

Publications10

  1. ncbi Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor-knockout mice after myocardial infarction
    Jun Katada
    Pfizer KEIO Research Laboratory, Tokyo, Japan
    Circulation 111:2157-64. 2005
    ..The molecular basis underlying this Ang II-independent remodeling is unclear...
  2. ncbi Significance of cyclooxygenase-2 induced via p38 mitogen-activated protein kinase in mechanical stimulus-induced peritoneal adhesion in mice
    Jun Katada
    KEIO Research Park 2N4, Keio University School of Medicine, Shinanomachi 35, Shinjuku ku, Tokyo 160 8582, Japan
    J Pharmacol Exp Ther 313:286-92. 2005
    ..In conclusion, COX-2, but not COX-1, plays a significant role in mechanical stimulus-induced peritoneal formation in the mouse cecum...
  3. ncbi Significance of vascular endothelial cell growth factor up-regulation mediated via a chymase-angiotensin-dependent pathway during angiogenesis in hamster sponge granulomas
    Jun Katada
    Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, Japan
    J Pharmacol Exp Ther 302:949-56. 2002
    ..Furthermore, a chymase-Ang II-VEGF pathway may operate in granulation tissue as the primary mediator of angiogenesis...
  4. ncbi Role of mast cell chymase in angiotensin-induced vascular contraction of hamster cheek pouch microvessels
    J Katada
    Life Science Research Center, Advanced Technology Research Laboratories, Kawasaki, Japan
    Eur J Pharmacol 379:63-72. 1999
    ..Treatment of microvessels with 100 microg/ml compound 48/80 enhanced angiotensin I-induced vascular contraction response, suggesting the significance of mast cells as a source of cheek pouch chymase...
  5. ncbi AT(2) receptor-dependent vasodilation is mediated by activation of vascular kinin generation under flow conditions
    Jun Katada
    Department of Pharmacology, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
    Br J Pharmacol 136:484-91. 2002
    ..Such vasodilation counterbalances AT(1)-dependent vasoconstriction to regulate the vascular tone...
  6. ncbi Discovery and structure--activity relationship studies of a novel and specific peptide motif, Pro-X-X-X-Asp-X, as a platelet fibrinogen receptor antagonist
    Y Hayashi
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, Kawasaki, Japan
    Bioorg Med Chem 6:355-64. 1998
    ....
  7. ncbi Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model
    M Muramatsu
    Department of Pharmacology, Kitasato University School of Medicine, 1 15 1 Kitasato Sagamihara shi, Kanagawa 228 8555, Japan
    J Biol Chem 275:5545-52. 2000
    ..Our results may suggest a potential ability of chymase to promote angiogenesis through the local chymase-dependent and angiotensin-converting enzyme-dependent Ang II generating system in pathophysiological angiogenesis...
  8. ncbi Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants
    M Majima
    Department of Pharmacology, Kitasato University School of Medicine, Kitasato 1 15 1, Sagamihara, Kanagawa 228 8555, Japan
    Br J Pharmacol 130:641-9. 2000
    ..These results suggested that COX-2 may enhance bFGF-induced neovascularization in sponge granuloma by PG-mediated expression of VEGF, and that a COX-2 inhibitor would facilitate the management of conditions involving angiogenesis...
  9. ncbi GPIIb/IIIa integrin antagonists with the new conformational restriction unit, trisubstituted beta-amino acid derivatives, and a substituted benzamidine structure
    Y Hayashi
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, 3 35 1 Ida, Nakahara ku, Kawasaki 211 0035, Japan
    J Med Chem 41:2345-60. 1998
    ..3-Substituted-2,2-dimethyl-beta-amino acid residues would serve as new and useful linear templates to restrict the conformational flexibility of peptidomimetics...
  10. ncbi Antitumor activity of phenylahistin in vitro and in vivo
    K Kanoh
    Life Science Research Center, Advanced Technology Research Laboratories, Nippon Steel Corporation, Kawasaki, Japan
    Biosci Biotechnol Biochem 63:1130-3. 1999
    ..8 x 10(-7) to 3.7 x 10(-6), while (+)-phenylahistin exhibited 33-100-fold less potent activity than (-)-phenylahistin did. (-)-Phenylahistin also showed antitumor activity against P388 leukemia and Lewis lung carcinoma cells in vivo...