Kyoko Ito

Summary

Affiliation: Meiji Seika Kaisha
Country: Japan

Publications

  1. ncbi Anti-cariogenic properties of a water-soluble extract from cacao
    Kyoko Ito
    Health and Bioscience Laboratories, Meiji Seika Kaisha, Ltd, Sakado, Saitama, Japan
    Biosci Biotechnol Biochem 67:2567-73. 2003
  2. ncbi Effects of Pro-Hyp, a collagen hydrolysate-derived peptide, on hyaluronic acid synthesis using in vitro cultured synovium cells and oral ingestion of collagen hydrolysates in a guinea pig model of osteoarthritis
    Hiroki Ohara
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, Sakado, Saitama, Japan
    Biosci Biotechnol Biochem 74:2096-9. 2010
  3. ncbi Enhanced absorption of anthocyanins after oral administration of phytic acid in rats and humans
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, 5 3 1, Chiyoda, Sakado shi, Saitama 350 0289, Japan
    J Agric Food Chem 55:2489-96. 2007
  4. ncbi Comparative assessment of distribution of blackcurrant anthocyanins in rabbit and rat ocular tissues
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha Ltd, 5 3 1 Chiyoda, Sakado shi, Saitama 350 0289, Japan
    Exp Eye Res 83:348-56. 2006
  5. ncbi Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, 5 3 1, Chiyoda, Sakado shi, Saitama 350 0289, Japan
    J Agric Food Chem 54:578-82. 2006
  6. ncbi Antioxidants suppress nitrofurazone-induced proliferation of hepatocytes
    Kyoko Ito
    Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
    Exp Toxicol Pathol 55:247-50. 2003
  7. ncbi Immunohistochemical study on inducible type of nitric oxide (iNOS), basic fibroblast growth factor (bFGF) and tumor growth factor-beta1 (TGF-beta1) in arteritis induced in rats by fenoldopam and theophylline, vasodilators
    Hisashi Ikegami
    Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
    Exp Toxicol Pathol 54:1-7. 2002
  8. ncbi Nitrofurazone induces non-regenerative hepatocyte proliferation in rats
    Kyoko Ito
    Yamanouchi Pharmaceutical Co, Ltd, Safety Research Laboratories, Tokyo, Japan
    Exp Toxicol Pathol 53:421-6. 2002
  9. ncbi Expression profile of AMPA receptor subunit mRNA in single adult rat brain and spinal cord neurons in situ
    Hui Sun
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Neurosci Res 52:228-34. 2005
  10. ncbi Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor-mediated excitotoxicity in ALS
    Hui Sun
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Neurochem 98:782-91. 2006

Collaborators

Detail Information

Publications10

  1. ncbi Anti-cariogenic properties of a water-soluble extract from cacao
    Kyoko Ito
    Health and Bioscience Laboratories, Meiji Seika Kaisha, Ltd, Sakado, Saitama, Japan
    Biosci Biotechnol Biochem 67:2567-73. 2003
    ..These results suggest that the addition of CEPWS to cariogenic food could be useful in controlling dental caries...
  2. ncbi Effects of Pro-Hyp, a collagen hydrolysate-derived peptide, on hyaluronic acid synthesis using in vitro cultured synovium cells and oral ingestion of collagen hydrolysates in a guinea pig model of osteoarthritis
    Hiroki Ohara
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, Sakado, Saitama, Japan
    Biosci Biotechnol Biochem 74:2096-9. 2010
    ..It also reduced the morphological changes associated with osteoarthritic cartilage destruction of the knee joint. The results suggest that collagen hydrolysates have therapeutic potential for treatment of osteoarthritis...
  3. ncbi Enhanced absorption of anthocyanins after oral administration of phytic acid in rats and humans
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, 5 3 1, Chiyoda, Sakado shi, Saitama 350 0289, Japan
    J Agric Food Chem 55:2489-96. 2007
    ..Yet, phytic acid, being a strong chelator of important minerals, contributes to mineral deficiencies. An interference with iron uptake has been reported. Safety tests are therefore necessary before high dose IP6 can be used in foods...
  4. ncbi Comparative assessment of distribution of blackcurrant anthocyanins in rabbit and rat ocular tissues
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha Ltd, 5 3 1 Chiyoda, Sakado shi, Saitama 350 0289, Japan
    Exp Eye Res 83:348-56. 2006
    ..Our data show clearly that intact forms of BCAs pass thorough the blood-aqueous barrier and blood-retinal barrier in both rats and rabbits...
  5. ncbi Ingested delphinidin-3-rutinoside is primarily excreted to urine as the intact form and to bile as the methylated form in rats
    Hitoshi Matsumoto
    Food and Health R and D Laboratories, Meiji Seika Kaisha, Ltd, 5 3 1, Chiyoda, Sakado shi, Saitama 350 0289, Japan
    J Agric Food Chem 54:578-82. 2006
    ..Our results indicate that delphinidin-3-rutinoside might be metabolized differently from cyanidin-3-glucoside and pelargonidin-3-glucoside...
  6. ncbi Antioxidants suppress nitrofurazone-induced proliferation of hepatocytes
    Kyoko Ito
    Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
    Exp Toxicol Pathol 55:247-50. 2003
    ..This suppression of NF-induced hepatocyte proliferation by antioxidants therefore strongly suggests that free radical production is involved in this process...
  7. ncbi Immunohistochemical study on inducible type of nitric oxide (iNOS), basic fibroblast growth factor (bFGF) and tumor growth factor-beta1 (TGF-beta1) in arteritis induced in rats by fenoldopam and theophylline, vasodilators
    Hisashi Ikegami
    Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
    Exp Toxicol Pathol 54:1-7. 2002
    ..On the other hand, TGF-beta1 was not considered to have a suppressive effect on iNOS expression in these models...
  8. ncbi Nitrofurazone induces non-regenerative hepatocyte proliferation in rats
    Kyoko Ito
    Yamanouchi Pharmaceutical Co, Ltd, Safety Research Laboratories, Tokyo, Japan
    Exp Toxicol Pathol 53:421-6. 2002
    ..The absence of cell damage indicates that NF-induced hepatocyte proliferation is different from regenerative proliferation that is seen after partial hepatectomy or cell necrosis...
  9. ncbi Expression profile of AMPA receptor subunit mRNA in single adult rat brain and spinal cord neurons in situ
    Hui Sun
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Neurosci Res 52:228-34. 2005
    ..The unique AMPA receptor expression profile of motoneurons may render them selectively vulnerable to AMPA receptor-mediated excitotoxicity...
  10. ncbi Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor-mediated excitotoxicity in ALS
    Hui Sun
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Neurochem 98:782-91. 2006
    ..e. calcium-permeable) AMPA receptors. This rat model may be useful in investigating ALS etiology...