Research Topics
Genomes and Genes | S YanagawaSummaryAffiliation: Kyoto University Country: Japan Publications
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Publications
Identification and characterization of a novel line of Drosophila Schneider S2 cells that respond to wingless signalingS Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606 8507, Japan
J Biol Chem 273:32353-9. 1998..S2R+ cells are as sensitive to Wg as are clone 8 cells but can grow in simpler medium. Therefore, the S2R+ cell line is likely to prove highly useful for in vitro analyses of Wg signaling...
Biochemical characterization of the Drosophila axin proteinS Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, 606 8507, Kyoto, Japan
FEBS Lett 474:189-94. 2000..Moreover, interactions between Daxin and Zeste-white 3, Armadillo, Dishevelled, protein phosphatase 2A and Daxin itself were shown, providing direct evidence that Daxin is a scaffold protein in the Wingless pathway...
Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virusS Yanagawa
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
J Virol 74:9786-91. 2000..Thus, Notch1 is a major target of provirus insertional mutagenesis in these T-cell lymphomas...
Asymmetric colocalization of Flamingo, a seven-pass transmembrane cadherin, and Dishevelled in planar cell polarizationY Shimada
Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Sakyo ku, 606 8502, Kyoto, Japan
Curr Biol 11:859-63. 2001....
Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathwayJ S Lee
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
J Biol Chem 274:21464-70. 1999..These results are direct evidence that Dsh family proteins mediate a set of conserved biochemical processes in the Wnt/Wg signaling pathway...
Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3J S Lee
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Japan
FEBS Lett 455:276-80. 1999..A potential role for overexpressed HES-1 in the development of the lymphoma was discussed...
Fv-1 restriction of endogenous feline C-type RD114 virus genome phenotypically mixed with ecotropic murine leukemia virusesK Kakimi
Department of Viral Oncology, Kyoto University
Jpn J Cancer Res 81:768-72. 1990..However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one-hit dose-response kinetics, even when titrated with murine cells with the restricted Fv-1 phenotype...
Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing eventsJ S Lee
Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo ku, Kyoto 606 8507, Japan
J Virol 73:5166-71. 1999..Interestingly, these two proteins showed different subcellular localizations in a mouse mammary epithelial cell line, HC-11...
The dishevelled protein is modified by wingless signaling in DrosophilaS Yanagawa
Howard Hughes Medical Institute, Department of Developmental Biology, Beckman Center, Stanford University, California 94305 5428, USA
Genes Dev 9:1087-97. 1995..We conclude that dsh, a highly conserved gene, is not merely a permissive factor in Wg signaling but encodes a novel signal transduction molecule, which may function between the Wg receptor and more downstream signaling molecules...
beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteinsW Chen
Department of Medicine, Howard Hughes Medical Institute, Duke University Medical Center, Box 3821, Durham, NC 27710, USA
Proc Natl Acad Sci U S A 98:14889-94. 2001....
