Research Topics
Species | Satoshi MoritaSummaryAffiliation: Kyoto University Country: Japan Publications
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Detail Information
Publications
Analysis of incomplete quality of life data in advanced stage cancer: a practical application of multiple imputationSatoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Kyoto, Japan
Qual Life Res 14:1533-44. 2005....- Study design and methods for a clinical trial of an oral carbonaceous adsorbent used to prevent the progression of chronic kidney disease (CAP-KD)Satoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto, 606 8501, Japan
Clin Exp Nephrol 9:219-27. 2005.... - Prognostic factors for a composite end-point of renal outcomes in patients with chronic kidney diseaseSatoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Kyoto, Japan
Ther Apher Dial 10:72-7. 2006..These factors should be considered as balancing variables for randomization in future clinical studies... - Determining the effective sample size of a parametric priorSatoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Kyoto 606 8501, Japan
Biometrics 64:595-602. 2008..We provide general guidelines for application, illustrate the method in several standard cases where the answer seems obvious, and then apply it to some nonstandard settings... - Application of an adaptive design to a randomized phase II selection trial in gastric cancer: a report of the study designSatoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Kyoto, Japan
Pharm Stat 5:109-18. 2006..The simulation study also evaluates the sensitivity of the design to the prior distribution by considering two alternative priors... - A phase I/II trial of a WT1 (Wilms' tumor gene) peptide vaccine in patients with solid malignancy: safety assessment based on the phase I dataSatoshi Morita
Department of Epidemiology and Health Care Research, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto 606 8501, Japan
Jpn J Clin Oncol 36:231-6. 2006..We conducted a phase I study to investigate the safety of a weekly WT1 tumor vaccine therapy in patients with solid tumors that had been refractory to all other anti-cancer therapies... - Influence of clinical parameters on quality of life during chemotherapy in patients with advanced non-small cell lung cancer: application of a general linear modelSatoshi Morita
Department of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto 606 8501, Japan
Jpn J Clin Oncol 33:470-6. 2003..The aim of this study was to determine the relative influence of physician-assessed clinical parameters, including non-hematological adverse events and performance status, on quality of life (QOL) during chemotherapy... - Multicenter phase II study of weekly paclitaxel plus S-1 combination chemotherapy in patients with advanced gastric cancerYuji Ueda
Department of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
Gastric Cancer 13:149-54. 2010..A multicenter phase II study was conducted to evaluate the efficacy and safety of a combination regimen of weekly paclitaxel plus S-1 in patients with advanced gastric cancer... - Individually different "weights" of quality of life assessment in patients with advanced nonsmall-cell lung cancerSatoshi Morita
QOL Evaluation Committee, West and East CPT 11 Lung Cancer Study Groups, and Dept of Epidemiological Clinical Research Information Mgmt, Kyoto Graduate School of Medicine, Yoshidakanoe cho, Sakyo ku, Kyoto 606 8501, Japan
J Clin Epidemiol 56:744-51. 2003..The structure of quality of life (QOL) assessment was investigated by estimating subject-specific as well as population-averaged "weights" for four domains (functional, physical, mental, and psychosocial) relative to global QOL... - Phase I study of a combination of s-1 and weekly paclitaxel in patients with advanced or recurrent gastric cancerYuji Ueda
Department of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
Oncology 69:261-8. 2005..Endpoints of this study were to examine the toxicity profile OF this regimen and to determine the recommended dose (rd) of paclitaxel... - Acylated ghrelin level in patients with OSA before and after nasal CPAP treatmentKen Ichi Takahashi
Department of Respiratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
Respirology 13:810-6. 2008..Plasma ghrelin is decreased in obese and increased in lean individuals. Of the two circulating forms of ghrelin, acylated and unacylated, the former is thought to be essential for the biological activity of ghrelin... - Quality of life improvements in dialysis patients receiving darbepoetin alfaShunichi Fukuhara
Department of Epidemiology and Healthcare Research, Kyoto University Graduate School of Medicine and Public Health, Kyoto, Japan
Ther Apher Dial 12:72-7. 2008..Vitality increased significantly only in those patients with the greatest increases in Hb concentration and in those with higher final Hb concentrations... - Assessment and data analysis of health-related quality of life in clinical trials for gastric cancer treatmentsSatoshi Morita
Department of Epidemiology and Health Care Research, School of Public Health, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan
Gastric Cancer 9:254-61. 2006..Although we address issues specific to the assessment of gastric cancer, many are applicable to clinical trials for different cancer types... - Phase I/II study of combination therapy of oral fluorinated pyrimidine compound S-1 with low-dose cisplatin in patients with unresectable and/or recurrent advanced gastric cancer: a novel study design to evaluate safety and efficacySatoshi Morita
Department of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
Jpn J Clin Oncol 34:159-61. 2004..The goal of this trial is to establish a useful chemotherapeutic treatment in an outpatient setting... - Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trialsJunichi Sakamoto
Department of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto, 606 8501, Japan
Cancer Immunol Immunother 55:404-11. 2006..72 (95% CI: 0.58-0.90; P=0.003). The results of this meta-analysis suggest that adjuvant immunochemotherapy with PSK can improve both survival and disease-free survival of patients with curatively resected colorectal cancer... - Physicians' reasons for not entering their patients in a randomized controlled trial in JapanMahbubur Rahman
Department of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine, Kyoto 606 8501, Japan
Tohoku J Exp Med 203:105-9. 2004.... - Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancerMasakazu Toi
Faculty of Medicine, Kyoto University, Kyoto, Japan
BMC Cancer 10:56. 2010..Here we investigate the relationship between HER2 expression or HER2 homodimers and OS in a clinic-based population of patients with MBC selected primarily by IHC... - Adjuvant chemotherapy for gastric cancer in Japan: global and Japanese perspectivesJunichi Sakamoto
Department of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, 606 8501 Kyoto, Japan
Cancer Chemother Pharmacol 54:S25-31. 2004..In conclusion, this therapy could become the standard adjuvant treatment regimen for gastric cancer patients after curative resection in Japan... - Effect of feedback in promoting adherence to an exercise programme: a randomized controlled trialMasaaki Shakudo
Department of Epidemiology and Healthcare Research, Kyoto University School of Public Health, Kyoto, Japan
J Eval Clin Pract 17:7-11. 2011..We investigated whether providing participants in an exercise programme with regular feedback on their exercise progress affected their adherence to the programme regimen... - Application of a continual reassessment method to a phase I clinical trial of capecitabine in combination with cyclophosphamide and epirubicin (CEX) for inoperable or recurrent breast cancerSatoshi Morita
Department of Epidemiological and Clinical Research Information Management, Kyoto University, Kyoto, Japan
Jpn J Clin Oncol 34:104-6. 2004..We conducted a survey of the clinical oncologists participating in this trial to determine the dose escalation/de-escalation rule, including a prior distribution for model parameters used in the CRM... - Heterogeneity in responsiveness of perceived quality of life to body composition changes between adult- and childhood-onset Japanese hypopituitary adults with GH deficiency during GH replacementHisashi Urushihara
Department of Epidemiology and Healthcare Research, Kyoto University School of Public Health, Yoshida Kyoto 606 8501, Japan
Eur J Endocrinol 156:637-45. 2007..To examine the responsiveness of quality of life (QoL) associated with changes in clinical indices relevant to GH deficiency (GHD) in Japanese hypopituitary adults... - Lifestyle and work predictors of fatigue in Japanese manufacturing workersShin Yamazaki
Department of Epidemiology and Healthcare Research, Graduate School of Medicine and Public Health, Kyoto University, Yoshida Konoecho, Sakyo ku, Kyoto 606 8501, Japan
Occup Med (Lond) 57:262-9. 2007..Fatigue is one of the most common symptoms encountered in medical practice. However, little is known about the causal relationship between change in lifestyle and fatigue... - Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial of cardiovascular events in high-risk hypertensive patients: rationale, design, and methodsTsuguya Fukui
Department of General Medicine and Clinical Epidemiology, School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan
Hypertens Res 26:979-90. 2003..In addition, the use of the ABCD system is expected to contribute to the development of more efficient data management systems for large-scale clinical trials... - [Planning, administration, and management of the clinical trial based on EBM -what are key points to generate valid evidence?]Junichi Sakamoto
Kyoto University Graduate School of Medicine, Department of Epidemiological and Clinical Research Information Management, Kyoto, Japan
Arerugi 53:413-6. 2004 - Plasma thioredoxin, a novel oxidative stress marker, in patients with obstructive sleep apnea before and after nasal continuous positive airway pressureKen Ichi Takahashi
Department of Respiratory Medicine, Kyoto University Graduate School of Medicine, Kyoto University, Kyoto, Japan
Antioxid Redox Signal 10:715-26. 2008..0002). The adiponectin level, but not the TRX level, was correlated with the BMI (n = 53; p = 0.02). Plasma TRX may be a unique marker for evaluating oxidative stress and monitoring the effectiveness of nCPAP in OSA patients... - A phase II clinical trial to evaluate the effect of paclitaxel in patients with ascites caused by advanced or recurrent gastric carcinoma: a new concept of clinical benefit response for non-measurable type of gastric cancerJunichi Sakamoto
Department of Epidemiological and Clinical Research Information Management, Kyoto University, Kyoto, Japan
Jpn J Clin Oncol 33:238-40. 2003.... - Wilms tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myelomaAkihiro Tsuboi
Department of Cancer Immunotherapy, Osaka University Graduate School of Medicine, 1 7 Yamada oka, Suita City, Osaka, Japan
Int J Hematol 86:414-7. 2007.... - Dose-finding phase I and pharmacokinetic study of capecitabine (Xeloda) in combination with epirubicin and cyclophosphamide (CEX) in patients with inoperable or metastatic breast cancerShigehira Saji
Department of Surgery and Breast Oncology, Division of Clinical Trials and Research, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
Oncology 72:330-7. 2007.... - The domain structure of the EORTC QLQ-STO22 supported by Japanese validation dataSatoshi Morita
Health and Community Medicine Program, Nagoya University Graduate School of Medicine, Nagoya, Japan
Psychooncology 17:474-9. 2008..Extensive discussions with the EORTC Group are needed from both cross-cultural and clinical perspectives in order to establish a consensus on the various language versions of the QLQ-STO22... - A randomized phase II selection trial in patients with advanced/recurrent gastric cancer: Trial for Advanced Stomach Cancer (TASC)Satoshi Morita
Department of Medical Administration, Program in Health and Community Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
Jpn J Clin Oncol 37:469-72. 2007..A Bayesian method is used to provide a statistical rule for monitoring the trial. Forty patients per treatment regimen (160 in total) were randomized into one of the four regimens using a centralized dynamic method... - Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiformeShuichi Izumoto
Department of Neurosurgery, Nagoya University, Nagoya, Japan
J Neurosurg 108:963-71. 2008..The object of this study was to investigate the safety and clinical responses of immunotherapy targeting the WT1 (Wilms tumor 1) gene product in patients with recurrent glioblastoma multiforme (GBM)... - From translational research to a large randomized clinical trial: a long and streanuous way from bench to bedsideJunichi Sakamoto
Young Leaders Program, Nagoya University Graduate School of Medicine, Japan
Nagoya J Med Sci 69:9-16. 2007.... - Physicians' attitudes towards and reasons for participation in the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trialMahbubur Rahman
Clinical Practice Evaluation and Research Center, St Luke s Life Science Institute, Tokyo 104 8560, Japan
J Epidemiol 15:38-40. 2005..The objectives of this study were to determine the reasons for physicians' participation in and attitudes towards the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial... - A phase I study of combination therapy of the oral fluorinated pyrimidine compound S-1 with low-dose cisplatin twice-a-week administration (JFMC27-9902 Step2) in patients with advanced gastric cancer using a continual reassessment methodSatoshi Morita
Program in Health and Community Medicine, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8550, Japan
Jpn J Clin Oncol 37:924-9. 2007.... - A randomized phase III trial of post-operative adjuvant oral fluoropyrimidine versus sequential paclitaxel/oral fluoropyrimidine; and UFT versus S1 for T3/T4 gastric carcinoma: the Stomach Cancer Adjuvant Multi-institutional Trial Group (Samit) TrialAkira Tsuburaya
Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Asahi ku, Yokohama 2410815, Japan
Jpn J Clin Oncol 35:672-5. 2005..This trial could appraise sequential combination therapy and efficacy of new drugs as adjuvant for gastric cancer treatment... - "Point of no return (PNR)" in progressive IgA nephropathy: significance of blood pressure and proteinuria management up to PNRHiroyuki Komatsu
First Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki, Miyazaki Japan
J Nephrol 18:690-5. 2005..They reported that the approximate PNR is serum creatinine (sCr) 3.0 mg/dL... - Estimation of the average causal effect among subgroups defined by post-treatment variablesYutaka Matsuyama
Department of Biostatistics, School of Health Sciences and Nursing, University of Tokyo, Tokyo, Japan
Clin Trials 3:1-9. 2006.... - Genotype of thymidylate synthase likely to affect efficacy of adjuvant 5-FU based chemotherapy in colon cancerTakanori Matsui
Department of Clinical Research, Aichi Cancer Center Aichi Hospital, Okazaki, Aichi 444 0011, Japan
Oncol Rep 16:1111-5. 2006..Furthermore, differences in the proportions of the TS genotypes can account for the interracial differences in the adverse effects of 5-FU-based chemotherapy... - Clinical validity of the Japanese version of the Functional Assessment of Cancer Therapy-Anemia ScaleMaya Kurita
Division of Clinical Research, National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan
Support Care Cancer 15:1-6. 2007..We also analyzed patients' scores for the related FACT-General scale (FACT-G), the FACT Anemia subscale, and the FACT Trial Outcome Index-Anemia scale (FACT TOI-An) to determine which was the most sensitive to anemia measurements... - Informed consent in the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial: a survey of collaborating physiciansTsuguya Fukui
Clinical Practice Evaluation and Research Center, St Luke s Life Science Institute, St Luke s International Hospital, Tokyo, Japan
Hypertens Res 29:471-4. 2006..2% favored some form of incentives for patients. The results of this study should be useful for efficiently implementing randomized controlled trials in Japan... - Reliability and validity of the Functional Assessment of Chronic Illness Therapy-Spiritual (FACIT-Sp) for Japanese patients with cancerWataru Noguchi
Section of Liaison Psychiatry and Palliative Medicine, Graduate School of Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, 113 8519 Tokyo, Japan
Support Care Cancer 12:240-5. 2004..These findings suggest that the Japanese version of the FACIT-Sp scale is satisfactory in terms of reliability and validity and is a useful tool in the study of spirituality among Japanese cancer patients... - Spiritual needs in cancer patients and spiritual care based on logotherapyWataru Noguchi
Section of Liaison Psychiatry and Palliative Medicine, Graduate School of Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
Support Care Cancer 14:65-70. 2006.... - Quality of life in gastric cancerAd A Kaptein
Psychology Unit, Leiden University Medical Center LUMC, PO Box 9555, 2300 RB Leiden, The Netherlands
World J Gastroenterol 11:3189-96. 2005..To summarize the empirical research on assessing quality of life (QOL) in patients with gastric carcinoma... - Grain growth and endosperm cell size under high night temperatures in rice (Oryza sativa L.)Satoshi Morita
Department of Lowland Farming Research, National Agricultural Research Center for Kyushu Okinawa Region, Chikugo, Fukuoka 833 0041, Japan
Ann Bot 95:695-701. 2005..Endosperm cell number and cell sizes were also examined to determine which might cause the decrease in final grain weight... - [Pilot-testing of the Japanese version of the EORTC QLQ-STO22 gastric cancer module]Satoshi Morita
Dept of Epidemiological and Clinical Research Information Management, Kyoto University Graduate School of Medicine
Gan To Kagaku Ryoho 31:1195-9. 2004..We are waiting for the result of the validation study in an international field (EORTC protocol number 15001/40003) with a larger number of gastric cancer patients using standardized psychometric testing... - [Reliability and validity of the functional assessment of chronic illness therapy-spiritual (FACIT-Sp) Japanese version in cancer patients--a preliminary study]Wataru Noguchi
Section of Liaison Psychiatry and Palliative Medicine, Graduate School of Tokyo Medical and Dental University
Gan To Kagaku Ryoho 31:387-91. 2004..The findings suggest that The Japanese version of FACIT-Sp is associated with satisfactory reliability and validity and is an effective tool in the study of spirituality among cancer patients... - Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 microg/body) in a patient with chronic myelomonocytic leukemiaManabu Kawakami
Department of Medicine, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan
Int J Hematol 85:426-9. 2007..This case demonstrates for the first time that vaccination with as little as 5 microg of WT1 peptide can induce WT1-specific immune responses and resultant clinical responses... - A randomized phase II trial of preoperative exercise to reduce operative risk in gastric cancer patients with metabolic syndrome: adjuvant exercise for general elective surgery (AEGES) study groupHaruhiko Cho
Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 1 1 2, Nakao, Asahi ku, Yokohama 2410815, Japan
Jpn J Clin Oncol 38:71-3. 2008..The sample size is 86 (43 for surgery alone and 43 for exercise group) to select promising treatment for Phase III trial in a randomized Phase II setting... - Health-related quality of life among Japanese women with iron-deficiency anemiaKiyoshi Ando
Department of Hematology and Oncology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
Qual Life Res 15:1559-63. 2006..0 g/dl) at baseline showed a dramatic improvement. Iron supplementation in IDA patients improves not only hemoglobin levels, but also physical function, vitality, and general health perception... - Clinical implications of peritoneal cytology in potentially resectable pancreatic cancer: positive peritoneal cytology may not confer an adverse prognosisSuguru Yamada
Department of Surgery II, Graduate School and Faculty of Medicine, University of Nagoya, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Ann Surg 246:254-8. 2007..To determine the value of peritoneal washing cytology (CY) in determining resectability of pancreatic cancer... - Recruitment of patients for a clinical trial: factors on the physician side and reasons on the patient sideTsuguya Fukui
Clinical Practice Evaluation and Research Center, St. Luke's Life Science Institute, St. Luke's International Hospital, Tokyo
Intern Med 45:511-4. 2006..CONCLUSION: Results of this study might be useful in predicting actual recruiters at the outset of clinical trials...