Research Topics
| Takeshi MorimotoSummaryAffiliation: Kyoto University Country: Japan Publications
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Detail Information
Publications
Incidence of adverse drug events and medication errors in Japan: the JADE studyTakeshi Morimoto
Center for Medical Education, Kyoto University Graduate School of Medicine, Konoe cho, Yoshida, Sakyo ku, Kyoto 606 8501, Japan
J Gen Intern Med 26:148-53. 2011..S. and Europe, and extrapolating from these data might not be valid, especially regarding selecting and prioritizing solutions...
Gender differences in effects of physical activity on quality of life and resource utilizationTakeshi Morimoto
Division of General Internal Medicine, Kyoto University Hospital, Kyoto 606 8507, Japan
Qual Life Res 15:537-46. 2006..Physical activity is associated with health-related quality of life (HRQOL) in the general population, but the effects may be different between sexes. In addition, the effects on resource utilization are not well elucidated...
Epidemiology of potentially inappropriate medication use in elderly patients in Japanese acute care hospitalsMio Sakuma
Center for Medical Education, Kyoto University Graduate School of Medicine, Kyoto, Japan
Pharmacoepidemiol Drug Saf 20:386-92. 2011....
Effects of BLS training on factors associated with attitude toward CPR in college studentsShinya Hamasu
Department of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Resuscitation 80:359-64. 2009..In order to elucidate the factors for willingness to perform CPR, we evaluated the responses of college students to questionnaires before and after basic life support (BLS) training...
Impact of social functioning and vitality on preference for life in patients with Parkinson's diseaseTakeshi Morimoto
Department of Clinical Epidemiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Mov Disord 18:171-5. 2003..5 months/year of disease and by 2.6 months/stage). Interventions that target social functioning and vitality may be beneficial to preference for life...
Cost-effectiveness of screening for coronary artery disease in asymptomatic patients with Type 2 diabetes and additional atherogenic risk factorsYasuaki Hayashino
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, Japan
J Gen Intern Med 19:1181-91. 2004..The present study aims to evaluate the cost-effectiveness of screening and determine acceptable strategies...
Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetesNeiko Ozasa
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
Hypertens Res 31:425-32. 2008..Pulse wave analysis may reveal hemodynamic alterations that affect LVM but that cannot be identified using a sphygmomanometer...
Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher RegistryTakeshi Kimura
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto, Japan
Circulation 125:584-91. 2012..There is a scarcity of long-term data from large-scale drug-eluting stent registries with a large enough sample to evaluate low-frequency events such as stent thrombosis (ST)...
Cardiac troponin T vs other biochemical markers in patients with congestive heart failureYukiko Nishio
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
Circ J 71:631-5. 2007....
Chronic obstructive pulmonary disease--an independent risk factor for long-term cardiac and cardiovascular mortality in patients with ischemic heart diseaseKei Nishiyama
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara chou, Shougoin, Sakyo ku, Kyoto 606 8397, Japan
Int J Cardiol 143:178-83. 2010..We examined how COPD affects long-term mortality and morbidity after undergoing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG)...
Three-year outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease: insights from the j-Cypher registryMamoru Toyofuku
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606 8507, Japan
Circulation 120:1866-74. 2009..Long-term outcomes after stenting of an unprotected left main coronary artery (ULMCA) with drug-eluting stents have not been addressed adequately despite the growing popularity of this procedure...
Clinical prediction rules for bacteremia and in-hospital death based on clinical data at the time of blood withdrawal for culture: An evaluation of their development and useTsukasa Nakamura
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
J Eval Clin Pract 12:692-703. 2006..73, 0.64, and 0.64, respectively, in original cohort and 0.72, 0.64, and 0.64 in validation respectively. CONCLUSIONS: The clinical prediction rules are helpful for improved clinical decision making for bacteremia patients...
Study design, statistical method, and level of evidence in Japanese and American clinical journalsTsuguya Fukui
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, Kyoto University Hospital, Japan
J Epidemiol 12:266-70. 2002..1% vs. 12.7%, p=0.001). The overall picture of Japanese medical articles seems to be improving recently, at least in terms of statistical methods toward more diversified and sophisticated way of use, compared to the previous data...
Is B-type natriuretic peptide-guided heart failure management cost-effective?Takeshi Morimoto
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
Int J Cardiol 96:177-81. 2004..When these two parameters were simultaneously put on the simulation model, the incremental costs of the BNP group may exceed $50,000. CONCLUSIONS: Introduction of BNP measurement in heart failure management may be cost-effective...
Clonal origin of germ cell colonies after spermatogonial transplantation in miceMito Kanatsu-Shinohara
Horizontal Medical Research Organization, Department of Molecular Genetics, Kyoto University, Japan
Biol Reprod 75:68-74. 2006..These results provide evidence that germ cell colonies develop from single spermatogonial stem cells...
Comparisons of baseline demographics, clinical presentation, and long-term outcome among patients with early, late, and very late stent thrombosis of sirolimus-eluting stents: Observations from the Registry of Stent Thrombosis for Review and Reevaluation Takeshi Kimura
Department of Cardiovascular of Medicine, Kyoto University, Japan
Circulation 122:52-61. 2010..Stent thrombosis (ST) after sirolimus-eluting stent implantation has not yet been adequately characterized, mainly because of its low incidence...
Effects of low dialysate calcium concentration on health-related quality of life in hemodialysis patientsYoshinori Taji
Department of Nephrology, Saiseikai Nakatsu Hospital, Osaka, Japan
Clin Exp Nephrol 9:153-7. 2005..We explored the effects of this calcium concentration on health-related quality of life (HRQOL) in hemodialysis patients...
Long-term outcomes of coronary-artery bypass graft surgery versus percutaneous coronary intervention for multivessel coronary artery disease in the bare-metal stent eraTakeshi Kimura
Department of Cardiovascular of Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto 606 8507 Japan
Circulation 118:S199-209. 2008..Observational registries comparing coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) have reported long-term survival results that are discordant with those of randomized trials...
In-patient interventions supported by results of randomized controlled trials in JapanHiroshi Koyama
Department of General Medicine and Clinical Epidemiology, Kyoto University Hospital and Graduate School of Medicine, Kyoto City, Japan
Int J Qual Health Care 14:119-25. 2002..To determine to what extent the results of randomized controlled trials (RCTs) support medical interventions for in-patients at the department of general medicine of a university hospital in Japan...
Public perception of and willingness to perform bystander CPR in JapanNobuo Kuramoto
Center for Medical Education, Kyoto University Graduate School of Medicine, Konoe cho, Yoshida, Sakyo ku, 606 8501 Kyoto, Japan
Resuscitation 79:475-81. 2008..We investigated the characteristics associated with willingness to attempt CPR among the Japanese general population...
Acute pancreatitis and the role of histamine-2 receptor antagonists: a meta-analysis of randomized controlled trials of cimetidineTakeshi Morimoto
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, Japan
Eur J Gastroenterol Hepatol 14:679-86. 2002..Until the results of a large randomized trial show otherwise, H2RAs should not be used in the absence of specific clinical indications...
Utilities measured by rating scale, time trade-off, and standard gamble: review and reference for health care professionalsTakeshi Morimoto
Department of Clinical Epidemiology, Kyoto University Graduate School of Medicine, Japan
J Epidemiol 12:160-78. 2002..There is a strong tendency for RS to yield the lowest and SG to yield the highest values. We compiled an extensive list of the results of studies on utility as a reference for health care professionals in this field...
More intensive lipid lowering is associated with regression of coronary atherosclerosis in diabetic patients with acute coronary syndrome--sub-analysis of JAPAN-ACS studyHidenori Arai
Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan
J Atheroscler Thromb 17:1096-107. 2010..The purpose of this study was to address the association of lipid levels after statin therapy with regression of atherosclerotic coronary lesions and major cardiovascular events in patients after ACS...
Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantationTakeshi Kimura
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara cho, Sakyo ku, Kyoto, Japan
Circulation 119:987-95. 2009..The influences of antiplatelet therapy discontinuation on the risk of stent thrombosis and long-term clinical outcomes after drug-eluting stent implantation have not yet been addressed adequately...
Clopidogrel resistance in Japanese patients scheduled for percutaneous coronary interventionKozo Hoshino
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Circ J 73:336-42. 2009..Clopidogrel, a 2(nd)-generation P2Y(12) blocker, has recently become available in Japan and this study aimed to evaluate its antiplatelet effects in Japanese patients...
Application of U.S. guidelines in other countries: aspirin for the primary prevention of cardiovascular events in JapanTakeshi Morimoto
Department of General Medicine and Clinical Epidemiology, Kyoto University Hospital and Kyoto University Graduate School of Medicine, Kyoto, Japan
Am J Med 117:459-68. 2004..S. population because of higher risks of hemorrhagic complications. The assumptions and implications of U.S. guidelines should be evaluated before use in other countries...
Impact of postgraduate education on physician practice for community-acquired pneumoniaHiroshi Ikai
Department of Primary Care and Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
J Eval Clin Pract 18:389-95. 2012....
Prognostic utility of T-wave alternans in a real-world population of patients with left ventricular dysfunction: the PREVENT-SCD studySatoshi Shizuta
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara cho, Shougoin, Sakyo ku, Kyoto, 606 8507, Japan
Clin Res Cardiol 101:89-99. 2012..The predictive value of T-wave alternans (TWA) for lethal ventricular tachyarrhythmia in patients with left ventricular (LV) dysfunction is controversial. Also, long-term arrhythmia risk of patients ineligible for the TWA test is unknown...
Optimal strategy for the first episode of primary spontaneous pneumothorax in young men. A decision analysisTakeshi Morimoto
Department of Clinical Epidemiology, Kyoto University Graduate School of Medicine, Japan
J Gen Intern Med 17:193-202. 2002..3%, pleurodesis becomes the preferred strategy. CONCLUSION: On the basis of the current best available data and patients' preference, thoracoscopic surgery can be considered the treatment of choice for the first episode of PSP...
Evaluation of the antiplatelet effects of cilostazol, a phosphodiesterase 3 inhibitor, by VASP phosphorylation and platelet aggregationHiromi Yamamoto
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Honmachi, Sakyo ku, Kyoto, Japan
Circ J 72:1844-51. 2008..Cilostazol, a phosphodiesterase 3 inhibitor, is an antiplatelet drug that is widely used for preventing cardiovascular events, although, to date, there are few methods for evaluating its effects...
High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative StudyNaoko Tanaka
Kyoto University Graduate School of Medicine, Kyoto, Japan
Arthritis Rheum 63:3625-32. 2011..Since somatic NLRP3 mosaicism has been detected in several mutation-negative NOMID/CINCA syndrome patients, we undertook this study to determine the precise contribution of somatic NLRP3 mosaicism to the etiology of NOMID/CINCA syndrome...
Aspirin for primary prevention of atherosclerotic disease in JapanTakeshi Morimoto
Center for Medical Education, Kyoto University Graduate School of Medicine, Japan
J Atheroscler Thromb 14:159-66. 2007..Thus, the JPAD trial should generate reliable data on primary prevention with aspirin for diabetic patients that would also be relevant to other countries...
Heritable imprinting defect caused by epigenetic abnormalities in mouse spermatogonial stem cellsJiyoung Lee
Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto, Japan
Biol Reprod 80:518-27. 2009..These results indicate that fetal germ cells have a limited ability to become pluripotent cells and lose the ability to undergo epigenetic reprogramming by in vitro culture...
[Cost-effectiveness analysis of ambulatory treatment for adult patients with community-acquired pneumonia: according to Japanese Respiratory Society guidelines]Takeshi Morimoto
Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
Nihon Kokyuki Gakkai Zasshi 40:17-25. 2002..AZM provides a higher quality of life for adults without comorbidity with generally acceptable marginal cost...
Meta-analysis of antiplatelet therapy for IgA nephropathyYoshinori Taji
Division of General Internal Medicine, Kyoto University Hospital, 54 Kawahara cho, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
Clin Exp Nephrol 10:268-73. 2006..To systematically evaluate the effects of antiplatelet agents for IgA nephropathy, we conducted a meta-analysis of the published studies...
Clinical significance of risedronate for osteoporosis in the initial treatment of male patients with Graves' diseaseTakafumi Majima
Department of Endocrinology and Metabolism, Rakuwakai Otowa Hospital, Kyoto, Japan
J Bone Miner Metab 24:105-13. 2006..We thus conclude that risedronate should be considered for the treatment of decreased bone mass associated with GD...
Action of aspirin on whole blood-aggregation evaluated by the screen filtration pressure methodArata Tabuchi
Department of Geriatric Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Circ J 72:420-6. 2008....
