Research Topics
Genomes and Genes | Kazushi KimuraSummaryAffiliation: Kyoto University Country: Japan Publications
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Publications
Neurite outgrowth from hippocampal neurons is promoted by choroid plexus ependymal cells in vitroKazushi Kimura
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto 606 8501, Japan
J Neurocytol 33:465-76. 2004....
Regulation of growth cone extension by SNARE proteinsKazushi Kimura
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
J Histochem Cytochem 51:429-33. 2003..On the other hand, overexpression of syntaxin1A neither promoted nor inhibited neurite outgrowth. Thus, VAMP-2 and SNAP-25A play different roles in neurite elongation and sprouting...
Neurogenesis in the ependymal layer of the adult rat 3rd ventricleYi Xu
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto 606 8501, Japan
Exp Neurol 192:251-64. 2005..These results indicate that neural progenitor cells exist in the ependymal layer of the adult rat 3rd ventricle and that they may differentiate into neurons functioning in the hypothalamus...
Isolation of neural stem cells from the forebrain of deceased early postnatal and adult rats with protracted post-mortem intervalsYi Xu
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Yoshidakonoe cho, Sakyo ku, Kyoto, Japan
J Neurosci Res 74:533-40. 2003..The neural stem cells from cadavers have great significance in terms of their clinical use as homografts for CNS regeneration...
Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytesNagatoki Kinoshita
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Yoshida konoe cho, Sakyo ku, Kyoto 606 8501, Japan
Genes Cells 9:1-14. 2004..Thus Sept2 may regulate GLAST-mediated glutamate uptake by astrocytes, which is important for appropriate transmitter signalling in the cerebellum...
Prostaglandin E receptor EP1 enhances GABA-mediated inhibition of dopaminergic neurons in the substantia nigra pars compacta and regulates dopamine level in the dorsal striatumYasuhiro Tanaka
Department of Pharmacology, Kyoto University Graduate School of Medicine, Sakyo ku, Kyoto, Japan
Eur J Neurosci 30:2338-46. 2009..Therefore, the prostaglandin E(2)-EP1 signaling directly enhances GABAergic inputs to SNc dopaminergic neurons. The lack of this EP1 action may lead to a hyperdopaminergic state of EP1-deficient mice...
Nogo-A expression in mature oligodendrocytes of rat spinal cord in association with specific moleculesMasanori Taketomi
Department of Anatomy and Neurobiology, Kyoto University Graduate School of Medicine, Kyoto 606 8501, Japan
Neurosci Lett 332:37-40. 2002..Nogo-A was co-immunoprecipitated with alpha-tubulin and myelin basic protein (MBP) from rat brain tissue. These results show that Nogo-A is expressed in association with tubulin and MBP in the mature oligodendrocytes...
Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channelKentaro Noma
Department of Biophysics, Graduate School of Science, Kyoto University, Oiwake, Kitashirakawa, Sakyo ku, Kyoto 606 8502, Japan
J Biol Chem 284:33139-50. 2009..Furthermore, we could not detect unglycosylated channels in the mouse brain. Our data suggest that only glycosylated Kv12.2 channels show proper voltage dependence and are utilized in vivo...
Nectin: an adhesion molecule involved in formation of synapsesAkira Mizoguchi
Department of Anatomy and Neurobiology, Faculty of Medicine, Kyoto University, Kyoto 606 8501, Japan
J Cell Biol 156:555-65. 2002..These results indicate an important role of the nectin-afadin system in the formation of synapses...
Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin releaseTetsushi Sadakata
Laboratory for Molecular Neurogenesis, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan
J Neurosci 27:2472-82. 2007..The possible involvement of the CAPS2 gene in the cerebellar deficits of autistic patients is discussed...
TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is up-regulated in colon carcinoma and involved in cell proliferation and cell aggregationYuji Toiyama
Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
World J Gastroenterol 13:2717-21. 2007..To investigate the expression patterns of TTYH2 in the human colon cancer and colon cancer cell lines and to evaluate the inhibitory effect of small interfering RNA (siRNA) on the expression of TTYH2 in colon cancer cell lines...
PASK (proline-alanine-rich Ste20-related kinase) binds to tubulin and microtubules and is involved in microtubule stabilizationTomonari Tsutsumi
Department of Neural Regeneration and Cell Communication, Mie University Graduate School of Medicine, Tsu, Mie 514 8507, Japan
Arch Biochem Biophys 477:267-78. 2008..Our findings suggest that PASK may regulate the cytoskeleton by modulating microtubule stability...
