Research Topics
Species | Takao KataokaSummaryAffiliation: Kyoto Institute of Technology Country: Japan Publications
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Detail Information
Publications
Translation inhibitors and their unique biological propertiesTakao Kataoka
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
Eur J Pharmacol 676:1-5. 2012..This perspective focuses on the biological properties of recently identified translation inhibitors that trigger ribotoxic stress response, particularly glutarimides as well as triene-ansamycins...
Chemical biology of inflammatory cytokine signalingTakao Kataoka
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto, Japan
J Antibiot (Tokyo) 62:655-67. 2009..This review focuses on recent progress in the identification and biological properties of small molecules targeting the NF-kappaB signaling pathway induced by pro-inflammatory cytokines...
Ferrochelatase catalyzes the formation of Zn-protoporphyrin of dry-cured ham via the conversion reaction from heme in meatTuan Thanh Chau
Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606 8585, Japan
J Agric Food Chem 59:12238-45. 2011..These findings can open up possible approaches for the generation of a nontoxic bright pigment, Zn-protoporphyrin, to shorten the incubation time required to produce dry-cured ham...
Cytotrienin A, a translation inhibitor that induces ectodomain shedding of TNF receptor 1 via activation of ERK and p38 MAP kinaseYuriko Yamada
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
Eur J Pharmacol 667:113-9. 2011....
Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokinesYuriko Yamada
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan
J Antibiot (Tokyo) 64:361-6. 2011..These results indicate that mycotrienin II is a direct inhibitor of translation, thereby inhibiting ICAM-1 expression induced by pro-inflammatory cytokines...
Roles of porphyrin and iron metabolisms in the ?-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin and photodamage of tumor cellsYoshiko Ohgari
Department of Biotechnology, Kyoto Institute of Technology, Kyoto, Japan
Photochem Photobiol 87:1138-45. 2011..These results indicated that not only the production of porphyrin intermediates but also the reuse of iron from heme and mitochondrial iron utilization control the ALA-induced accumulation of protoporphyrin in cancerous cells...
Peperomins as anti-inflammatory agents that inhibit the NF-kappaB signaling pathwayChieko Tsutsui
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
Bioorg Med Chem Lett 19:4084-7. 2009..Our present results clearly demonstrate that peperomins inhibit the NF-kappaB signaling pathway by blocking IkappaB kinase activation...
Egr-1 regulates the transcriptional repression of mouse ?-aminolevulinic acid synthase 1 by hemeSaki Gotoh
Department of Biotechnology, Kyoto Institute of Technology, Japan
Gene 472:28-36. 2011..These results suggest that Egr-1-NABs complex is involved in the regulation of the transcription of ALAS1 by heme, leading to the regulation of the heme biosynthesis...
Eudesmane-type sesquiterpene lactones inhibit multiple steps in the NF-?B signaling pathway induced by inflammatory cytokinesRyuichi Tamura
Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo ku, Kyoto 606 8585, Japan
Bioorg Med Chem Lett 22:207-11. 2012..Our present study reveals that eudesmane-type ?-methylene ?-lactones and ?-bromo ketones inhibit multiple steps in the NF-?B signaling pathway induced by IL-1? and TNF-?...
