Research Topics
Species | Minako Yamaoka-TojoSummaryAffiliation: Kitasato University Country: Japan Publications
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Publications
Circulating interleukin-18: A specific biomarker for atherosclerosis-prone patients with metabolic syndromeMinako Yamaoka-Tojo
Department of Rehabilitation, Kitasato University School of Allied Health Sciences, 1 15 1 Kitasato, Minami Ku, Sagamihara, 252 0373 Kanagawa, Japan
Nutr Metab (Lond) 8:3. 2011..abstract:..
Ezetimibe and reactive oxygen speciesMinako Yamaoka-Tojo
Department of Rehabilitation, Kitasato University School of Allied Health Sciences, 1 15 1 Kitasato, Minami Ku, Sagamihara, Kanagawa 252 0373, Japan
Curr Vasc Pharmacol 9:109-20. 2011....
Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular diseaseMinako Yamaoka-Tojo
Department of Rehabilitation, Kitasato University School of Allied Health Sciences, 1 15 1 Kitasato, Minami Ku, Sagamihara, 252 0373, Japan
Cardiovasc Diabetol 9:17. 2010..In spite of good effects of these drugs in diabetic patients, circulating levels of incretins and their role in MetS are largely unknown...
Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemiaMinako Yamaoka-Tojo
Department of Rehabilitation, Kitasato University School of Allied Health Sciences, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
Lipids Health Dis 8:41. 2009..Ezetimibe has been reported to reduce LDL-C safely with both monotherapy and combination therapy with statins...
Beyond cholesterol lowering: pleiotropic effects of bile acid binding resins against cardiovascular disease risk factors in patients with metabolic syndromeMinako Yamaoka-Tojo
Department of Cardioangiology, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
Curr Vasc Pharmacol 6:271-81. 2008....
C-reactive protein-induced production of interleukin-18 in human endothelial cells: a mechanism of orchestrating cytokine cascade in acute coronary syndromeMinako Yamaoka-Tojo
Department of Internal Medicine and Cardiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
Heart Vessels 18:183-7. 2003..This suggests that CRP may contribute to the mechanism of coronary artery disease in addition to being an incidental product of various types of systemic inflammation...
Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failureMinako Yamaoka-Tojo
Department of Cardiology, Kitasato University School of Medicine, Sagamihara
Intern Med 45:429-34. 2006..Treatment of alpha-MSH could modify the immunobalance between inflammatory and anti-inflammatory responses in cultured PBMC. These findings suggest that alpha-MSH may play an important role in the pathophysiology of CHF...
Dual response to Fas ligation in human endothelial cells: apoptosis and induction of chemokines, interleukin-8 and monocyte chemoattractant protein-1Minako Yamaoka-Tojo
The First Department of Internal Medicine, Yamagata University School of Medicine, Japan
Coron Artery Dis 14:89-94. 2003..We also investigated whether an inhibitor of caspase-8 (Z-IETD-FMK) does modulate IL-8 and MCP-1 secretion...
Adaptation to low-intensity exercise on a cycle ergometer by patients with acute myocardial infarction undergoing phase I cardiac rehabilitationAtsuhiko Matsunaga
Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan
Circ J 68:938-45. 2004..05), whereas there was no change in group A. CONCLUSION: Factors influencing a significant elevation of blood pressure during phase I rehabilitation are age, physical deconditioning, imbalance of autonomic nervous activity and anxiety...
Circulating levels of interleukin 18 reflect etiologies of heart failure: Th1/Th2 cytokine imbalance exaggerates the pathophysiology of advanced heart failureMinako Yamaoka-Tojo
Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
J Card Fail 8:21-7. 2002..The findings suggest an important role for IL-18 in the pathophysiology of CHF and provide a direction for more specific immunomodulating therapy...
Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemiaTaiki Tojo
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Circulation 111:2347-55. 2005..The role of gp91phox-derived ROS in neovascularization in response to tissue ischemia is unknown, however...
IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferationMinako Yamaoka-Tojo
Division of Cardiology Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Circ Res 95:276-83. 2004....
IQGAP1 regulates reactive oxygen species-dependent endothelial cell migration through interacting with Nox2Satoshi Ikeda
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Arterioscler Thromb Vasc Biol 25:2295-300. 2005..We thus hypothesized that Nox2 and IQGAP1 may play important roles in ROS-dependent EC migration in response to injury...
