Research Topics
Species | Tetsuro SasadaSummaryAffiliation: Kitano Hospital Country: Japan Publications
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Detail Information
Publications
Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancerTetsuro Sasada
Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan
Ann Surg Oncol 15:609-17. 2008..The aim of this study was to evaluate the prognostic significance of IEX-1 expression in pancreatic cancer...- Intra-arterial infusion chemotherapy with 5-fluorouracil and cisplatin in advanced pancreatic cancer: a feasibility studyTetsuro Sasada
Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan
Am J Clin Oncol 31:71-8. 2008..Our aim was to examine the efficacy and tolerability of intra-arterial infusion chemotherapy with 5-fluorouracil (5-FU) and cisplatin in advanced pancreatic cancer... - CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progressionTetsuro Sasada
Department of Surgery, Tazuke Kofukai Kitano Hospital, 2 4 20 Ohgimachi, Kita ku, Osaka 530 8480, Japan
Cancer 98:1089-99. 2003..The purpose of the current study was to demonstrate the possible involvement of CD4+CD25+ regulatory T cells in immune system impairment in patients with gastrointestinal malignancies... - Preventive effect of a traditional herbal medicine, Hochu-ekki-to, on immunosuppression induced by surgical stressMotohide Kimura
Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Kita ku, Osaka 530 8480, Japan
Surg Today 38:316-22. 2008..To examine the effect of preoperative administering of a Japanese traditional herbal medicine, Hochu-ekki-to (TJ-41), on immunosuppression induced by surgical stress in patients with gastrointestinal malignancies... - Usefulness of 99mTc-sestamibi scintigraphy in suggesting the therapeutic effect of chemotherapy against gastric cancerKenji Kawata
Department of Surgery, Tazuke-Kofukai Medical Research Institute and Kitano Hospital, Osaka, Japan
Clin Cancer Res 10:3788-93. 2004..7%) to chemotherapy with epirubicin, which is known to be a substrate of P-gp transporter. CONCLUSIONS: (99m)Tc-MIBI scintigraphy is useful to suggest the responses to chemotherapy of patients with advanced gastric cancer... - Diffusion-weighted magnetic resonance imaging for detecting lymph node metastasis of rectal cancerYo Mizukami
Department of Gastroenterological Surgery, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, 2 4 20, Ohgimachi, Kita ku, Osaka, 530 8480, Japan
World J Surg 35:895-9. 2011..Preoperative diagnosis of lymph node metastasis is important in determining the optimal therapy for rectal cancer. It has been shown that diffusion-weighted magnetic resonance imaging (DWI) is a useful tool for detecting malignant tumors... - Immediate early response gene X-1, a stress-inducible antiapoptotic gene, encodes cytotoxic T-lymphocyte (CTL) epitopes capable of inducing human leukocyte antigen-A33-restricted and tumor-reactive CTLs in gastric cancer patientsTetsuro Sasada
Department of Surgery, Tazuke-Kofukai Kitano Hospital, Osaka, Japan
Cancer Res 64:2882-8. 2004.... - Change in mitochondrial membrane potential in peripheral blood lymphocytes, especially in natural killer cells, is a possible marker for surgical stress on the immune systemArimichi Takabayashi
Department of Surgery, Kitano Hospital, Tazuke-Kofukai Medical Research Institute, Osaka, 530-8480, Japan
World J Surg 27:659-65. 2003..Monitoring of Delta Psi(m) in PBL after operation may be one of the useful markers for estimating the magnitude of surgical stresses on the immune system... - Uneventful splenectomy and cholecystectomy in a patient treated with anti-interleukin-6 receptor antibody therapyMorihiko Ishizaki
Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan
Langenbecks Arch Surg 393:423-5. 2008..However, in humans, the roles of IL-6 in acute phase responses after surgery remain poorly understood... - Personalized peptide vaccination in patients with refractory non-small cell lung cancerKoichi Yoshiyama
Department of Surgery, Kurume University School of Medicine, Kurume, Fukuoka, Japan
Int J Oncol 40:1492-500. 2012..Evaluation of the identified factors before or at an early stage of vaccination could be potentially useful for selecting NSCLC patients who would likely have better prognosis following PPV... - Increased levels of IgG antibodies against peptides of the prostate stem cell antigen in the plasma of pancreatic cancer patientsMasahiro Tanaka
Department of Immunology, Kurume University School of Medicine, Kurume 830 0011, Japan
Oncol Rep 18:161-6. 2007.... - New peptide vaccine candidates for epithelial cancer patients with HLA-A3 supertype allelesSatoko Matsueda
Department of Immunology, Karume University School of Medicine, Karume, Fukuoka, Japan
J Immunother 30:274-81. 2007..This information could expand the chance of a peptide-based cancer vaccine for epithelial cancer patients of many ethnic populations... - The TCR C beta FG loop regulates alpha beta T cell developmentMaki Touma
Laboratory of Immunobiology, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
J Immunol 176:6812-23. 2006..Collectively, our results show that the unique Cbeta FG loop appendage primarily controls alphabeta T cell development through selection processes... - Ran, a small GTPase gene, encodes cytotoxic T lymphocyte (CTL) epitopes capable of inducing HLA-A33-restricted and tumor-reactive CTLs in cancer patientsKoichi Azuma
Department of Immunology and Research Center of Innovative Cancer Therapy of the 21st Century Center of Excellence Program for Medical Science, Kurume University School of Medicine, Kurume, Japan
Clin Cancer Res 10:6695-702. 2004.... - Involvement of the TCR Cbeta FG loop in thymic selection and T cell functionTetsuro Sasada
Laboratory of Immunobiology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115
J Exp Med 195:1419-31. 2002..Compared with N15alphabeta, N15alphabeta.betaDeltaFG T cells respond poorly to cognate antigens and weak agonists. Thus, the Cbeta FG loop facilitates negative selection of thymocytes and activation of T cells... - Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitorEmma Fiorini
Laboratory of Immunobiology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
Mol Cell 9:637-48. 2002..Retroviral transduction of I kappa BNS in fetal thymic organ culture enhances TCR-triggered cell death consistent with its function in selection... - Baicalin induces apoptosis via mitochondrial pathway as prooxidantShugo Ueda
Department of Biological Responses, Institute for Virus Research, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, 606-8507, Kyoto, Japan
Mol Immunol 38:781-91. 2002..These results indicate that baicalin acts as a prooxidant and induces caspase-3 activation and apoptosis via mitochondrial pathway... - Thioredoxin-mediated redox control of human T cell lymphotropic virus type I (HTLV-I) gene expressionTetsuro Sasada
Department of Biological Responses, Institute for Virus Research, Kyoto University, 53 Kawahara cho, Shogoin, Sakyo ku, 606 8507, Kyoto, Japan
Mol Immunol 38:723-32. 2002..Taken together, these findings suggest that overexpressed TRX, which is induced by HTLV-I Tax, may play an important role in HTLV-I infection through the negative regulation of viral gene expression... - CD2 facilitates differentiation of CD4 Th cells without affecting Th1/Th2 polarizationTetsuro Sasada
Laboratory of Immunobiology, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
J Immunol 168:1113-22. 2002..Collectively, these results indicate that CD2 is important for the efficient development of CD4 SP thymocytes and TCR-dependent activation of mature CD4 lymph node T cells, but does not direct a particular helper T cell subset polarity...