Research Topics
Species | Takeshi KikuchiSummaryCountry: Japan Publications
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Detail Information
Publications
Rapid screening assay for KRAS mutations by the modified smart amplification processKenji Tatsumi
Genome Exploration Research Group Genome Network Project Core Group, RIKEN Genomic Sciences Center, RIKEN Yokohama Institute, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa, Japan
J Mol Diagn 10:520-6. 2008..The PNA-clamp SMAP-2 method is a rapid, simple, and highly sensitive detection assay for cancer mutations...
Sensitive detection of EGFR mutations using a competitive probe to suppress background in the SMart Amplification ProcessYuki Kawai
Genome Exploration Research Group Genome Network Project Core Group, Genomic Sciences Center GSC, RIKEN Yokohama Institute, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
Biologicals 36:234-8. 2008..The CP approach is another tool enhancing the effectiveness and versatility of SMAP 2 assays, expanding its potential applications, and reinforcing its position as a highly effective technology for molecular diagnostics...
Use of a competitive probe in assay design for genotyping of the UGT1A1 *28 microsatellite polymorphism by the smart amplification processJun Watanabe
RIKEN, Yokohama, Japan
Biotechniques 43:479-84. 2007..These results illustrate the versatility of SMAP-2 for molecular diagnostics and provide a new approach for enhancing SMAP-2 assay specificity...
Rapid SNP diagnostics using asymmetric isothermal amplification and a new mismatch-suppression technologyYasumasa Mitani
Genome Exploration Research Group Genome Network Project Core Group, RIKEN Genomic Sciences Center GSC, RIKEN Yokohama Institute, 1 7 22 Suehiro cho, Tsurumi ku, Yokohama, Kanagawa, 230 0045, Japan
Nat Methods 4:257-62. 2007..With these new tools, a high-precision and rapid DNA amplification technology becomes available to aid in pharmacogenomic research and molecular-diagnostics applications...
Rapid detection of epidermal growth factor receptor mutations in lung cancer by the SMart-Amplification ProcessKanako Hoshi
Genome Exploration Research Group Genome Network Project Core Group, RIKEN Genomic Sciences Center, RIKEN Yokohama Institute, 1 7 22 Suehiro cho, Japan
Clin Cancer Res 13:4974-83. 2007..Previous reports have been based mainly on diagnostic screening by sequencing. However, sequencing is a time-consuming and complicated procedure, not suitable for routine clinical use...
