Osamu Kanie

Summary

Country: Japan

Publications

  1. ncbi Analysis of behavior of sodiated sugar hemiacetals under low-energy collision-induced dissociation conditions and application to investigating mutarotation and mechanism of a glycosidase
    Osamu Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida shi, Tokyo, Japan
    Proc Jpn Acad Ser B Phys Biol Sci 85:204-15. 2009
  2. ncbi Ion-trap mass spectrometry unveils the presence of isomeric oligosaccharides in an analyte: stage-discriminated correlation of energy-resolved mass spectrometry
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Carbohydr Res 344:384-94. 2009
  3. ncbi Identification of genes required for neural-specific glycosylation using functional genomics
    Miki Yamamoto-Hino
    Research Group of Glycobiology and Glycotechnology, Mitsubishi Kagaku Institute of Life Sciences, Tokyo, Japan
    PLoS Genet 6:e1001254. 2010
  4. ncbi Sequential enzymatic glycosyltransfer reactions on a microfluidic device: Synthesis of a glycosaminoglycan linkage region tetrasaccharide
    Yasunari Ono
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo, 194 8511, Japan
    Lab Chip 8:2168-73. 2008
  5. ncbi High-yielding and controlled dissociation of glycosides producing B- and C-ion species under collision-induced dissociation MS/MS conditions and use in structural determination
    Katsuhiko Suzuki
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Anal Chem 79:9022-9. 2007
  6. ncbi N-Hexyl-4-aminobutyl glycosides for investigating structures and biological functions of carbohydrates
    Katsuhiko Suzuki
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Org Biomol Chem 7:4726-33. 2009
  7. ncbi Insight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometry
    Yoshimi Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida, Tokyo, Japan
    PLoS ONE 4:e5434. 2009
  8. ncbi Analysis of a series of isomeric oligosaccharides by energy-resolved mass spectrometry: a challenge on homobranched trisaccharides
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Minamiooya 11, Machida shi, Tokyo 194 8511 Japan
    Rapid Commun Mass Spectrom 23:3713-9. 2009
  9. ncbi Discrimination of 16 structural isomers of fucosyl galactoside based on energy-resolved mass spectrometry
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida shi, Tokyo, Japan
    J Am Soc Mass Spectrom 18:1873-9. 2007
  10. ncbi Anomeric information obtained from a series of synthetic trisaccharides using energy resolved mass spectra
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences, Machida shi, Tokyo, Japan
    J Mass Spectrom 42:714-23. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Analysis of behavior of sodiated sugar hemiacetals under low-energy collision-induced dissociation conditions and application to investigating mutarotation and mechanism of a glycosidase
    Osamu Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida shi, Tokyo, Japan
    Proc Jpn Acad Ser B Phys Biol Sci 85:204-15. 2009
    ..On the basis of these results, we could 1) observe the mutarotation of lactose and 2) speculate the hydrolysis mechanism of endo-glycosylceramidase by using mass spectrometry...
  2. ncbi Ion-trap mass spectrometry unveils the presence of isomeric oligosaccharides in an analyte: stage-discriminated correlation of energy-resolved mass spectrometry
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Carbohydr Res 344:384-94. 2009
    ....
  3. ncbi Identification of genes required for neural-specific glycosylation using functional genomics
    Miki Yamamoto-Hino
    Research Group of Glycobiology and Glycotechnology, Mitsubishi Kagaku Institute of Life Sciences, Tokyo, Japan
    PLoS Genet 6:e1001254. 2010
    ..This first large-scale genetic screen for glycosylation-related genes has revealed novel regulation of fucTA mRNA in neural cells...
  4. ncbi Sequential enzymatic glycosyltransfer reactions on a microfluidic device: Synthesis of a glycosaminoglycan linkage region tetrasaccharide
    Yasunari Ono
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo, 194 8511, Japan
    Lab Chip 8:2168-73. 2008
    ..Also, the kinetic parameters for a recently identified glycosyltransferase, proteoglycan GalT-I, were obtained for the first time...
  5. ncbi High-yielding and controlled dissociation of glycosides producing B- and C-ion species under collision-induced dissociation MS/MS conditions and use in structural determination
    Katsuhiko Suzuki
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Anal Chem 79:9022-9. 2007
    ....
  6. ncbi N-Hexyl-4-aminobutyl glycosides for investigating structures and biological functions of carbohydrates
    Katsuhiko Suzuki
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Org Biomol Chem 7:4726-33. 2009
    ....
  7. ncbi Insight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometry
    Yoshimi Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida, Tokyo, Japan
    PLoS ONE 4:e5434. 2009
    ..The regulation mechanism such glycan synthesis remains largely unknown...
  8. ncbi Analysis of a series of isomeric oligosaccharides by energy-resolved mass spectrometry: a challenge on homobranched trisaccharides
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Minamiooya 11, Machida shi, Tokyo 194 8511 Japan
    Rapid Commun Mass Spectrom 23:3713-9. 2009
    ..It was found that these structurally related glycans could be distinguished by taking advantage of differences in their activation energies in ERMS...
  9. ncbi Discrimination of 16 structural isomers of fucosyl galactoside based on energy-resolved mass spectrometry
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences MITILS, Machida shi, Tokyo, Japan
    J Am Soc Mass Spectrom 18:1873-9. 2007
    ..Furthermore, it was shown that alpha-glycosidic linkages of fucose were more reactive than the beta-isomers and the secondary glycosides were more reactive than the primary glycosides...
  10. ncbi Anomeric information obtained from a series of synthetic trisaccharides using energy resolved mass spectra
    Shusaku Daikoku
    Mitsubishi Kagaku Institute of Life Sciences, Machida shi, Tokyo, Japan
    J Mass Spectrom 42:714-23. 2007
    ..It is suggested that this finding may be useful in structural analysis of natural oligosaccharides...
  11. ncbi 3,4-Dihydroxypyrrolidine as glycosidase inhibitor
    Katsuhiko Suzuki
    Mitsubishi Kagaku Institute of Life Sciences, MITILS, Machida shi, Tokyo, Japan
    Curr Top Med Chem 9:34-57. 2009
    ..This review focuses on such "difficult to predict" species in an attempt to extract information or common aspects for the future development of inhibitors of glycosidases based on transition-state mimetics...
  12. ncbi Comparative RP-HPLC for rapid identification of glycopeptides and application in off-line LC-MALDI-MS analysis
    Yoshimi Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minamiooya, Machida shi, Tokyo 194 8511, Japan
    Carbohydr Res 343:758-68. 2008
    ..The results suggest that the method is useful in the analysis of glycoproteins...
  13. ncbi Analysis of pyridylaminated oligosaccharides using liquid chromatography-mass spectrometry with a monolithic capillary column
    Yoshimi Kanie
    Mitsubishi Kagaku Institute of Life Sciences MITILS, 11 Minami oya, Machida shi, Tokyo 194 8511, Japan
    J Chromatogr A 1216:4121-4. 2009
    ..Furthermore, our studies revealed an important difference in the separation profile, i.e., the monolithic capillary column could resolve smaller oligosaccharides to a greater extent...
  14. ncbi N-Glycosylation of the Drosophila neural protein Chaoptin is essential for its stability, cell surface transport and adhesive activity
    Yu Hirai-Fujita
    Mitsubishi Kagaku Institute of Life Sciences, 11 Minamiooya, Machida, Tokyo, Japan
    FEBS Lett 582:2572-6. 2008
    ..Mutation of 2/3 of the glycosylation sites resulted in a marked decrease in Chp protein abundance. These results suggest that N-linked glycosylation of Chp is essential for its stability and activity...
  15. ncbi Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (II)
    Yuhua Jin
    Kyoritsu University of Pharmacy, Tokyo, Japan
    Chem Pharm Bull (Tokyo) 54:485-92. 2006
    ....