A Kaneko

Summary

Country: Japan

Publications

  1. ncbi Malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the Vanuatu Archipelago
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical College, Japan
    Acta Trop 70:285-302. 1998
  2. ncbi Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Shinjuku ku, Tokyo 162 8666, Japan
    J Infect Dis 179:974-9. 1999
  3. ncbi Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Pharmacogenetics 9:317-26. 1999
  4. ncbi High and variable frequencies of CYP2C19 mutations: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Pharmacogenetics 9:581-90. 1999
  5. ncbi Malaria eradication on islands
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Lancet 356:1560-4. 2000
  6. ncbi High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi
    B Bwijo
    Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162 8666, Japan
    Acta Trop 85:363-73. 2003

Collaborators

Detail Information

Publications6

  1. ncbi Malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the Vanuatu Archipelago
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical College, Japan
    Acta Trop 70:285-302. 1998
    ..Different malaria endemicities possibly then selected different prevalences of G6PD deficiency over many generations...
  2. ncbi Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Shinjuku ku, Tokyo 162 8666, Japan
    J Infect Dis 179:974-9. 1999
    ..The results suggest that the parent compound proguanil has significant intrinsic efficacy against falciparum and vivax malaria independent of the metabolite cycloguanil...
  3. ncbi Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Pharmacogenetics 9:317-26. 1999
    ..The incidence was, however, similar in poor and extensive metabolizers. In conclusion, our data demonstrate an association between CYP2C19 mutations and poor metabolism of proguanil...
  4. ncbi High and variable frequencies of CYP2C19 mutations: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Pharmacogenetics 9:581-90. 1999
    ..This suggests that the majority of Pacific Islanders metabolize a wide variety of clinically important drugs to a significantly lower degree than the average European...
  5. ncbi Malaria eradication on islands
    A Kaneko
    Department of International Affairs and Tropical Medicine, Tokyo Women s Medical University School of Medicine, Japan
    Lancet 356:1560-4. 2000
    ..We aimed to assess whether malaria can be eliminated on isolated islands...
  6. ncbi High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi
    B Bwijo
    Department of International Affairs and Tropical Medicine, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162 8666, Japan
    Acta Trop 85:363-73. 2003
    ....