Research Topics
| Masami KojimaSummaryAffiliation: Kanazawa Medical University Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Influence of anesthesia on ocular effects and temperature in rabbit eyes exposed to microwavesMasami Kojima
Department of Ophthalmology, Kanazawa Medical University, Kanazawa, Japan
Bioelectromagnetics 25:228-33. 2004..The more pronounced ocular effects in the anesthetized rabbits were associated with the significantly higher ocular temperatures in the anesthetized animals. The influence of systemic anesthesia on ocular changes should be considered...
Low vitamin E level as a subliminal risk factor in a rat model of prednisolone-induced cataractMasami Kojima
Department of Ophthalmology, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku gun, Ishikawa, Japan
Invest Ophthalmol Vis Sci 43:1116-20. 2002....
Acute ocular injuries caused by 60-Ghz millimeter-wave exposureMasami Kojima
Division of Vision Research for Environmental Health, Medical Research Institute, Kanazawa Medical University, 1 1, Daigaku, Uchinada machi, Ishikawa, 920 0293, Japan
Health Phys 97:212-8. 2009..These findings indicate that the three types of millimeter-wave antennas can cause thermal injuries of varying types and levels. The thermal effects induced by millimeter-waves can apparently penetrate below the surface of the eye...
Efficacy of alpha-lipoic acid against diabetic cataract in ratMasami Kojima
Department of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan
Jpn J Ophthalmol 51:10-3. 2007..alpha-Lipoic acid (LA) is well known as a powerful antioxidant. The efficacy of dihydrolipoate-LA for oral administration against streptozotocin (STZ)-induced diabetic cataract in rat was investigated...
Environmental temperature and cataract progression in experimental rat cataract modelsMasami Kojima
Department of Ophthalmology, Kanazawa Medical University, Kahoku gun, Ishikawa Ken, Japan
Dev Ophthalmol 35:125-34. 2002..To clarify whether or not ambient temperature relates to cataract development or the progression of cataract formation...
Effect of 5-S-GAD on UV-B-induced cataracts in ratsHiroyoshi Kawada
Department of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan
Jpn J Ophthalmol 53:531-5. 2009..This is a report of an investigation of the effect of 5-S-GAD (eyedrops) on UVB-induced cataracts in rats...
Racial differences of lens transparency properties with aging and prevalence of age-related cataract applying a WHO classification systemKazuyuki Sasaki
Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
Ophthalmic Res 36:332-40. 2004..To investigate racial differences of lens transparency properties and the prevalence of lens opacification by age...
Ultraviolet B-induced corneal and lens damage in guinea pigs on low-ascorbic acid dietKaili Wu
Department of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan
Ophthalmic Res 36:277-83. 2004..No significant morphological differences in cornea and lens were found between guinea pigs fed with low-ASA or normal diet...
An alternative method of steroid-induced lens opacification in brown norway rat eyes applying systemic pulse administrationKouta Nagai
Department of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan
Ophthalmic Res 36:231-6. 2004..To confirm whether long-term administration of prednisolone sodium succinate (prednisolone) alone is able to induce cataract in rat eyes...
Prevalence of primary cornea guttata and morphology of corneal endothelium in aging Japanese and Singaporean subjectsKitagawa Kitagawa
Department of Ophthalmology, Kanazawa Medical University, Uchinada, Ishikawa 920 0293, Japan
Ophthalmic Res 34:135-8. 2002..These differences support not only a racial and a gender factor but also a possible environmental influence...
The effects of protective eyewear on glare and crystalline lens transparencyYasuo Sakamoto
Department of Ophthalmology, Kanazawa Medical University, Kahoku gun, Ishikawa Ken, Japan
Dev Ophthalmol 35:93-103. 2002..We investigated the relationship between different levels of crystalline lens transparence and the effects of glare protection using two kinds of filters...
High prevalence of nuclear cataract in the population of tropical and subtropical areasHiroshi Sasaki
Department of Ophthalmology, Kanazawa Medical University, Uchinada
Dev Ophthalmol 35:60-9. 2002....
Risk factors for nuclear lens opacification: the Reykjavik Eye StudyArsaell Arnarsson
Department of Ophthalmology, University Hospital, Reykjavik, Iceland
Dev Ophthalmol 35:12-20. 2002..CONCLUSIONS: Ageing is a major risk factor for nuclear lens opacification, and smoking is a major modifiable risk factor. Cortical and nuclear lens opacifications do not share the same modifiable risk factors...
Computation of temperature elevation in rabbit eye irradiated by 2.45-GHz microwaves with different field configurationsAkimasa Hirata
Department of Computer Science and Engineering, Nagoya Institute of Technology, Japan
Health Phys 94:134-44. 2008..45-GHz microwave systems. That position was found to appear around the posterior of the lens regardless of the exposure condition, which indicates that the original temperature distribution in the eye was the dominant factor...
Lens and cataract research of the 20th century: a review of results, errors and misunderstandingsOtto Hockwin
Center of Ophthalmology, Rheinische Friedrich Wilhelms Universitat Bonn, Germany
Dev Ophthalmol 35:1-11. 2002..In our opinion lens and cataract research is still necessary and it will be more successful if we bear in mind the mostly unintentional errors of the 20th century but keep them out of our daily practice...
Computational verification of anesthesia effect on temperature variations in rabbit eyes exposed to 2.45 GHz microwave energyAkimasa Hirata
Department of Computer Science and Engineering, Nagoya Institute of Technology, Nagoya, Japan
Bioelectromagnetics 27:602-12. 2006..The point to be stressed is that under anesthesia the thermoregulatory response was inactivated and blood flow and basal metabolism was reduced...
Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic ratsKiyoshi Ichikawa
Pharmacology Laboratories, Kissei Pharmaceutical Co Ltd, Hotaka, Nagano, Japan
Clin Exp Pharmacol Physiol 29:423-7. 2002..5. The results indicate that KAD-1229 has an antihyperglycaemic effect and KAD-1229 is suggested to be a suitable agent for controlling post-prandial hyperglycaemia...
Computational model for calculating body-core temperature elevation in rabbits due to whole-body exposure at 2.45 GHzAkimasa Hirata
Nagoya Institute of Technology, Japan
Phys Med Biol 53:3391-404. 2008..0 W kg(-1), the body-core temperature in rabbits elevates with time, without becoming saturated. The administration of anesthesia suppressed body-core temperature elevation, which is attributed to the reduced basal metabolic rate...
Differential analysis of D-beta-Asp-containing proteins found in normal and infrared irradiated rabbit lensTakumi Takata
Research Reactor Institute, Kyoto University, Kumatori-cho, Sennan, Osaka 590-0494, Japan
Biochem Biophys Res Commun 344:263-71. 2006..Additionally, some d-beta-Asp-containing proteins only appear after IR irradiation. One such protein is the alpha-enolase, which shows homology to tau-crystallin...
Temperature rises in the crystalline lens from focal irradiationTsutomu Okuno
National Institute of Industrial Health, Japan, 6 21 1 Nagao, Tama ku, Kawasaki City, Kanagawa Ken, 214 8585 Japan
Health Phys 88:214-22. 2005..The risk of thermal injury increases as exposure duration increases, and the risk tends to increase as the beam waist diameter or Maxwellian-view angle decreases...
Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animalsKiyoto Hara
Pharmacology Research Laboratory, Research and Development, Kissei Pharmaceutical Co, Ltd, 4365 Kashiwabara, Hotaka, Minamiazumi, Nagano 399-8304, Japan
J Toxicol Sci 28:25-34. 2003..The experimental model of monkeys is recommended for estimation of the clinical effects and safety of KFA-1411 in humans...
Mouse model of airway remodeling: strain differencesKazuhiko Shinagawa
Pharmacology Lab, Kissei Pharmaceutical Co Ltd, Minamiazumi, Nagano, Japan
Am J Respir Crit Care Med 168:959-67. 2003..In particular, useful qualitative and quantitative information relating to the structural and histologic changes in the lungs may be obtainable using this model...
Pharmacological profile of KUL-7211, a selective beta-adrenoceptor agonist, in isolated ureteral smooth muscleYoshitaka Tomiyama
Central Research Laboratory, Kissei Pharmaceutical Co, Ltd, Nagano, Japan
J Pharmacol Sci 92:411-9. 2003..KUL-7211 may be a novel and useful medication for relieving ureteral colic and promoting stone passage in urolithiasis patients...
Oxcarbazepine antinociception in animals with inflammatory pain or painful diabetic neuropathySumiyoshi Kiguchi
Pharmacology Research, R and D, Kissei Pharmaceutical Co Ltd, 4365 1 Kashiwabara, Hotaka, Minamiazumi, Nagano 399 8304, Japan
Clin Exp Pharmacol Physiol 31:57-64. 2004..6. These results indicate that OCBZ has an analgesic action and is a possible therapeutic agent for the treatment of neuropathic pain, such as occurs in painful diabetic neuropathy...
Rat model of the hypercalcaemia induced by parathyroid hormone-related protein: characteristics of three bisphosphonatesYoshimitsu Komatsu
Central Research Laboratory, R and D, Kissei Pharmaceutical Co Ltd, 4365 1, Kashiwabara, Hotaka, Minamiazumi, Nagano 399 8304, Japan
Eur J Pharmacol 507:317-24. 2005..These data indicated that clodronate and pamidronate not only decrease the plasma Ca2+ concentration but also improve the renal dysfunction induced by hypercalcaemia...
