Research Topics
Species | Tomoyuki HishidaSummaryCountry: Japan Publications
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Publications
Extraskeletal osteosarcoma arising in anterior mediastinum: brief report with a review of the literatureTomoyuki Hishida
Division of Thoracic Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Chiba, Japan
J Thorac Oncol 4:927-9. 2009..Complete surgical resection was successfully performed, and histologically the tumor contained osteoid formation consisting of round atypical cells. The literature concerning this rare tumor is reviewed...
Is surgical resection indicated for a solitary non-small cell lung cancer recurrence?Tomoyuki Hishida
Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Cardiovasc Surg 131:838-42. 2006..Some investigators have reported long-term survival after surgical resection of a solitary non-small cell lung cancer recurrence in various sites. However, the role and indications of the second operation remain unclear...
Problems in the current diagnostic standards of clinical N1 non-small cell lung cancerT Hishida
Department of Thoracic Oncology, National Cancer Centre Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba, 277 8577 Japan
Thorax 63:526-31. 2008..One possible reason may be that cN1disease diagnosed by current standard imaging modalities often contains unexpected N2 disease. This study was conducted to evaluate the surgical and pathological results of patients with cN1 NSCLC...
Prognostic impact of node involvement pattern in pN1 non-small cell lung cancer patientsMasayuki Nakao
Division of Thoracic Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:1576-82. 2010..The purpose of this study was to evaluate the prognostic effect of node involvement patterns in pN1 non-small cell lung cancer (NSCLC) patients, with special attention given to any differences between SCC and adenocarcinoma (AD)...
Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formationKeiju Aokage
Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Int J Cancer 128:1585-95. 2011..001) expression in comparison with cancer cells in BVBs. Our results suggested that in the early phase of metastatic tumor formation cancer cells undergo dynamic phenotypic change associated with EMT and subsequent MET...
Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancerRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, and daggerDepartment of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:1246-50. 2010..The purpose of this study was to quantify the risk of late recurrence in patients with stage IA non-small cell lung cancer (NSCLC) who remained recurrence-free for more than 5 years after resection...
Risk Factors for Tumor Recurrence in Patients With Early-Stage (Stage I and II) Non-small Cell Lung Cancer: Patient Selection Criteria for Adjuvant Chemotherapy According to the Seventh Edition TNM ClassificationRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
Chest 140:1494-502. 2011..The purpose of this study was to evaluate risk factors for tumor recurrence in patients with completely resected early-stage non-small cell lung cancer (NSCLC)...
Late recurrence of non-small cell lung cancer more than 5 years after complete resection: incidence and clinical implications in patient follow-upRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba, 277 8577, Japan
Chest 138:145-50. 2010..The purpose of this study was to evaluate the risk of late recurrence in patients who had undergone complete resection for non-small cell lung cancer (NSCLC) and remained recurrence-free for > or = 5 years...
Prognostic impact of node involvement pattern in pulmonary pN1 squamous cell carcinoma patientsMasayuki Nakao
Division of Thoracic Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Chiba, Japan
J Thorac Oncol 5:504-9. 2010..The purpose of this study was to evaluate the prognostic impact of lymph node involvement patterns in pulmonary pN1 SCC patients...
Possible delayed cut-end recurrence after limited resection for ground-glass opacity adenocarcinoma, intraoperatively diagnosed as Noguchi type B, in three patientsJunji Yoshida
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
J Thorac Oncol 5:546-50. 2010..However, recently three of the 24 patients, with mixed GGO lesions intraoperatively diagnosed as type B, developed a solid lesion at the cut-end scar...
Long-term survival and risk factors for recurrence in stage I non-small cell lung cancer patients with tumors up to 3 cm in maximum dimensionRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
Chest 138:357-62. 2010....
Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasmsMasakazu Kojika
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
Mod Pathol 22:1341-50. 2009....
Differences between squamous cell carcinoma and adenocarcinoma of the lung: are adenocarcinoma and squamous cell carcinoma prognostically equal?Akikazu Kawase
Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwanoha, Kashiwa, Chiba, Japan
Jpn J Clin Oncol 42:189-95. 2012..We analyzed pulmonary squamous cell carcinoma and adenocarcinoma patient survival in our single institution database, to evaluate the relationship of histologic analysis to survival and tumor aggressiveness...
Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinomaMasayuki Nakao
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Cancer 115:2732-43. 2009....
Prognostic significance of a solid component in pulmonary adenocarcinomaYoichi Ohtaki
Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Ann Thorac Surg 91:1051-7. 2011....
Influence of cigarette smoking on histological subtypes of stage I lung adenocarcinomaRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 6:743-50. 2011..The purpose of this study was to examine the association between cigarette smoking and histological subtypes of lung adenocarcinoma...
Subcarinal lymph node in upper lobe non-small cell lung cancer patients: is selective lymph node dissection valid?Keiju Aokage
Division of Thoracic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
Lung Cancer 70:163-7. 2010..It appears valid to omit subcarinal node dissection in upper lobe NSCLC patients, especially in clinical N0 squamous cell carcinoma patients...
Extratumoral vascular invasion is a significant prognostic indicator and a predicting factor of distant metastasis in non-small cell lung cancerYoshihisa Shimada
Division of Thoracic Surgery, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:970-5. 2010....
Two lung adenocarcinomas in the same lobe: multiple primaries or intrapulmonary metastasis?Kentaro Yoshimoto
Department of Thoracic Oncolog, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
Ann Thorac Cardiovasc Surg 17:584-7. 2011..Although we expected EGFR gene mutation analysis would help us distinguish the 2 lesions from each other, it was of little help. Disease history can be more important in evaluating multiple pulmonary cancers...
Poor prognostic factors in patients with stage IB non-small cell lung cancer according to the seventh edition TNM classificationRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277 8577, Japan
Chest 139:855-61. 2011..This study investigated poor prognostic factors in patients with stage IB non-small cell lung cancer (NSCLC) according to the seventh edition of the TNM classification...
Tumor invasion of extralobar soft tissue beyond the hilar region does not affect the prognosis of surgically resected lung cancer patientsHajime Otsuka
Division of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:1571-5. 2010..The purpose of this study is to evaluate the significance of tumor invasion of that region as a prognostic factor...
Visceral pleural invasion classification in non-small cell lung cancerAkikazu Kawase
Division of Thoracic Surgery, National Cancer Center Hospital East, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:1784-8. 2010....
Histological progression of small intrapulmonary metastatic tumor from primary lung adenocarcinomaKeiju Aokage
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Pathol Int 60:765-73. 2010..These findings suggest that implanted cancer cells display lepidic growth in the early metastatic phase and recapitulate the morphological heterogeneity of the original tumor as the metastasis enlarges...
Centrally located adenocarcinoma with endobronchial polypoid growth: clinicopathological analysis of five casesTomoyuki Hishida
Pathology Division, Research Center for Innovative Oncology, Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan
Pathol Int 61:73-9. 2011....
The prognostic impact of cigarette smoking on patients with non-small cell lung cancerRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
J Thorac Oncol 6:735-42. 2011....
Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinomaYoichi Ohtaki
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 5:1507-15. 2010..Alternatively, activated macrophages (M2 phenotype) are known to be related to tumor progression and outcome, and CD204 has been reported to be expressed in M2 macrophages in some tumors...
Clinicopathological characteristics of primary lung adenocarcinoma predominantly composed of goblet cells in surgically resected casesHideomi Ichinokawa
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba
Pathol Int 61:423-9. 2011..In conclusion, APGC formed a distinct subset and should be considered separately from lung adenocarcinoma based on frequent involvement of the left and lower lung and lack of central fibrosis...
The impact on survival of positive intraoperative pleural lavage cytology in patients with non-small-cell lung cancerKeiju Aokage
Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Cardiovasc Surg 139:1246-52, 1252.e1. 2010..The aim of this study was to analyze intraoperative pleural lavage cytology results in patients with non-small-cell lung cancer and quantify the impact on survival and recurrence...
Late pulmonary metastasis of a rectal cancer resected 20 years after low anterior resectionKenji Takahashi
Department of Thoracic Oncology, National Cancer Center Hospital East, Tokyo, Japan
Ann Thorac Cardiovasc Surg 14:386-9. 2008..This shows that pulmonary metastasis from colorectal cancer is possible even 20 years after the initial operation...
Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patientsYusuke Takahashi
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 6:1460-7. 2011..The aim of this study was to examine whether the histological properties of peritumoral stroma are correlated with squamous cell carcinoma (SqCC) aggressiveness and clinical outcome...
Prognostic impact of histology on early-stage non-small cell lung cancerRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Chest 140:135-45. 2011..The purpose of this study is to evaluate the significance of histology as a predictor of recurrence after resection in patients with early-stage non-small cell lung cancer...
Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinomaAkikazu Kawase
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Int J Cancer 123:1053-9. 2008..092). The results of this study highlight the importance of podoplanin expression by CAFs and provide new insights into the biology of the cancer microenvironment in adenocarcinoma of the lung...
Complete left-sided pericardial defect in a lung cancer patient undergoing pneumonectomy without closure of the defectYoshihisa Shimada
Division of Thoracic Surgery, National Cancer Center Hospital East, 6 5 1 Kashiwanoha, Kashiwa, Chiba, Japan
Ann Thorac Cardiovasc Surg 17:67-70. 2011..Complete pericardial defects usually do not endanger the lives of patients, and if the patient is asymptomatic, surgical repair of the defect may be unnecessary even during a left pneumonectomy...
Expression of podoplanin, CD44, and p63 in squamous cell carcinoma of the lungYoshihisa Shimada
Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Cancer Sci 100:2054-9. 2009....
Number of circulating endothelial progenitor cells and intratumoral microvessel density in non-small cell lung cancer patients: differences in angiogenic status between adenocarcinoma histologic subtypesRyo Maeda
Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 7:503-11. 2012....
Prognostic impact of intratumoral vascular invasion in non-small cell lung cancer patientsRyo Maeda
Department of Thoracic Oncology, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
Thorax 65:1092-8. 2010..The purpose of this study was to evaluate its significance as a risk factor for recurrence...
The role of pulmonary resection in tumors metastatic from head and neck carcinomasHiroyuki Daiko
Department of Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Jpn J Clin Oncol 40:639-44. 2010..The purpose of this study was to determine the role of surgical treatment and to identify factors affecting the survival of patients undergoing pulmonary resection for tumors metastatic from head and neck carcinomas...
Malignant granular cell tumor of the posterior mediastinum with disseminationMasayuki Nakao
Division of Thoracic Surgery, Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Asian Cardiovasc Thorac Ann 20:71-3. 2012..Histologically, the tumor was composed of cells with large eosinophilic and granular cytoplasm, which were strongly positive for S-100. Mediastinal malignant granular cell tumor with pleural dissemination is extremely unusual...
Predictive Factors of Pathologically Proven Noninvasive Tumor Characteristics in T1aN0M0 Peripheral Non-small Cell Lung CancerYoshihisa Shimada
Division of Thoracic Surgery, National Cancer Center Hospital East, 6 5 1, Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
Chest 141:1003-9. 2012....
Risk factors of postoperative respiratory infections in lung cancer surgerySatoshi Shiono
Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
J Thorac Oncol 2:34-8. 2007..Postoperative infections have been a major issue in lung cancer surgery. We changed our perioperative prophylactic antibiotic policy to a single dose of cefazolin before and after surgery in July 2002...
Multiple sclerosing hemangiomas with a 10-year historyTomoyuki Hishida
Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277-8577, Japan
Jpn J Clin Oncol 35:37-9. 2005..We followed this patient by annual chest CT scans for 10 years and demonstrated that all residual nodules remained unchanged. This is the first report of stable multiple pulmonary sclerosing hemangiomas observed for such a long period...
Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimensYoshihisa Shimada
Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Lung Cancer 75:368-73. 2012..The aim of this study was to elucidate the clinical features of high-grade neuroendocrine carcinoma (HGNEC)-probable LCNEC diagnosed by biopsy, and compare therapeutic efficacy with patients with SCLC...
Differences in clinicopathological and biological features between central-type and peripheral-type squamous cell carcinoma of the lungTakamoto Saijo
Pathology Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan
Lung Cancer 52:37-45. 2006..These results suggest that C-type and P-type SCC have different clinicopathological and biological features...
Malignant glomus tumor of the lungTomoyuki Hishida
Thoracic Surgery Division, National Cancer Center Hospital, Tokyo, Japan
Pathol Int 53:632-6. 2003..We believe that this is the fourth reported case of malignant glomus tumor of the lung...
Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cellsHakan Akca
Biology Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan
Lung Cancer 54:25-33. 2006..This specific property due to EGFR mutation could be an important step of multistage lung cancer progression...
