Research Topics
Species | Yoshihito YokoyamaSummaryAffiliation: Hirosaki University School of Medicine Country: Japan Publications
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Detail Information
Publications
Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancerY Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
Arch Gynecol Obstet 263:206-7. 2000..We report a patient suffering from acute nonlymphocytic leukemia (ANLL) 3 years after treatment for stage IV ovarian cancer began...
Clinical outcome and risk factors for recurrence in borderline ovarian tumoursY Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
Br J Cancer 94:1586-91. 2006..However, in cases of serous type and/or receiving cystectomy special care should be given as relative risk rates of recurrence elevate by 2-4-folds...
A phase II multicenter trial of concurrent chemoradiotherapy with weekly nedaplatin in advanced uterine cervical carcinoma: Tohoku Gynecologic Cancer Unit StudyYoshihito Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan
Oncol Rep 19:1551-6. 2008..4%) and 1 (2.2%), respectively. These results indicate that weekly nedaplatin of 30 mg/m(2) with concurrent radiotherapy is an effective and well-tolerated regimen for advanced squamous cell carcinoma of the uterine cervix...
Combination of ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, and cisplatin enhances the inhibition of growth of human ovarian cancersYoshihito Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
J Cancer Res Clin Oncol 137:1219-28. 2011..In this study, we investigated the effects of combination of ciglitazone, a PPAR? ligand, and cisplatin, a cytotoxic anti-cancer drug, on growth of ovarian cancer...
Asymptomatic intracardiac metastasis from a low-grade endometrial stromal sarcoma with successful surgical resectionYoshihito Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
Gynecol Oncol 92:999-1001. 2004..A case of a patient who successfully underwent surgical extraction of metastatic tumors of the low-grade ESS in the right ventricle is described in the present report...
Expression of vascular endothelial growth factor (VEGF)-D and its receptor, VEGF receptor 3, as a prognostic factor in endometrial carcinomaYoshihito Yokoyama
Reproductive Molecular Research Group, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom
Clin Cancer Res 9:1361-9. 2003..To evaluate the prognostic value of vascular endothelial growth factor (VEGF)-D and VEGF receptor (VEGFR)-3 in endometrial carcinoma...
Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinomaY Yokoyama
Department of Obstetrics and Gynaecology, University of Cambridge, The Rose Maternity Hospital, UK
Br J Cancer 88:237-44. 2003..Since VEGF-D was found to be an independent predictor of poor outcome, its measurement, together with other prognostic markers may improve prospective identification of patients with a poor prognosis...
Alopecia related to low dose oral contraceptiveY Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
Arch Gynecol Obstet 266:46-7. 2002..Although LD-OC scarcely induce troublesome side effects if prescribed in accordance with Managing Contraceptive Pill Patients Guideline, this trouble might become a source of poor compliance to LD-OCs...
Primary non-Hodgkin's lymphoma of the uterine cervixY Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
Arch Gynecol Obstet 265:108-11. 2001..She had a complete remission with a combination of chemotherapy and radiotherapy. Measurement of the serum soluble interleukin-2 receptor level was a useful index of the effectiveness of treatment...
Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancerYoshihito Yokoyama
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Amori, Japan
Mol Cancer Ther 6:1379-86. 2007..We conclude that CA could be an effective agent in ovarian cancer and should be tested alone and in combination with other anticancer drugs...
Peroxisome proliferator-activated receptor alpha and gamma ligands inhibit the growth of human ovarian cancerTatsuhiko Shigeto
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori 036 8562, Japan
Oncol Rep 18:833-40. 2007..These findings indicate that the combination of CA and pioglitazone produces a potent antitumor effect on ovarian cancer through reduction of AP-1 expression...
Inhibitory effect of meloxicam, a selective cyclooxygenase-2 inhibitor, and ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, on the growth of human ovarian cancersBing Xin
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
Cancer 110:791-800. 2007....
Anti-tumor effect of non-steroidal anti-inflammatory drugs on human ovarian cancersBing Xin
Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
Pathol Oncol Res 13:365-9. 2007....
Phase II clinical study of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of recurrent ovarian cancer (Tohoku Gynecologic Cancer Unit 101 Group Study)Tadahiro Shoji
Department of Obstetrics and Gynecology, Iwate Medical University School of Medicine, Morioka, Japan
Int J Gynecol Cancer 21:44-50. 2011..To evaluate the efficacy and safety of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of patients with recurrent ovarian cancer after previous treatment with platinum and taxane agents...
Para-aortic lymphadenectomy may improve disease-related survival in patients with multipositive pelvic lymph node stage IIIc endometrial cancerToshio Fujimoto
Department of Obstetrics and Gynecology, Akita University School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
Gynecol Oncol 107:253-9. 2007..The purpose of this study was to determine whether para-aortic lymphadenectomy improves disease-related survival (DRS) in stage IIIc endometrial cancer...
Identifying prognostic factors in Japanese women with pseudomyxoma peritonei: a retrospective clinico-pathological study of the Tohoku Gynecologic Cancer UnitTakanobu Kojimahara
Yamagata University School of Medicine, Department of Obstetrics and Gynecology, Yamagata, Japan
Tohoku J Exp Med 223:91-6. 2011..064). In conclusion, the macroscopic residual tumor is an important prognostic factor in Japanese patients with PMP...
Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: carbonyl reductase predicts prognosis and lymph node metastasisAkihiro Murakami
Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, 1 1 1 Minamikogushi, Ube 755 8505, Japan
Cancer Lett 311:77-84. 2011..This clinical result is supported by the in vitro data which show that suppression of CR expression promotes cancer cell invasion with decreased E-cadherin expression and increased MMP-2, -9 secretion...
Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancersM Wakui
Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
J Cancer Res Clin Oncol 136:1143-50. 2010....
A case of uterine leiomyoma with intravenous leiomyomatosis--histological investigation of the pathological condition--Asami Fukuyama
Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
Pathol Oncol Res 17:171-4. 2011....
Malignant ovarian tumors with induced expression of carbonyl reductase show spontaneous regressionHui Wang
Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
Clin Med Insights Oncol 6:107-15. 2012..The present study investigated tumor proliferation in a tumor model using murine ovarian cancer cells with increased carbonyl reductase (CR) expression...
Different susceptibility to peroxisome proliferator-induced hepatocarcinogenesis in rats with polymorphic glutathione transferase genesToshihiro Kudo
Second Department of Biochemistry, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
Cancer Sci 97:703-9. 2006..These results indicate that rats that are polymorphic for the GST M1 gene exhibit different susceptibilities to CF in vivo...
Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual functionAlexander G Marneros
Department of Cell Biology, Harvard Medical School, 188 Longwood Ave, Boston, MA 02115, USA
Am J Pathol 167:1451-9. 2005..Thus, hypoxia-inducible factor-1alpha-independent expression of VEGF is essential for choroid development...
[Mass-screening for ovarian cancer]Shigemi Sato
Department of Obstetrics and Gynecology, Hirosaki City Hospital
Nippon Rinsho 62:601-4. 2004
