Yoshihito Yokoyama

Summary

Affiliation: Hirosaki University School of Medicine
Country: Japan

Publications

  1. ncbi Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancer
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 263:206-7. 2000
  2. ncbi Clinical outcome and risk factors for recurrence in borderline ovarian tumours
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Br J Cancer 94:1586-91. 2006
  3. ncbi A phase II multicenter trial of concurrent chemoradiotherapy with weekly nedaplatin in advanced uterine cervical carcinoma: Tohoku Gynecologic Cancer Unit Study
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan
    Oncol Rep 19:1551-6. 2008
  4. ncbi Combination of ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, and cisplatin enhances the inhibition of growth of human ovarian cancers
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
    J Cancer Res Clin Oncol 137:1219-28. 2011
  5. ncbi Asymptomatic intracardiac metastasis from a low-grade endometrial stromal sarcoma with successful surgical resection
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Gynecol Oncol 92:999-1001. 2004
  6. ncbi Expression of vascular endothelial growth factor (VEGF)-D and its receptor, VEGF receptor 3, as a prognostic factor in endometrial carcinoma
    Yoshihito Yokoyama
    Reproductive Molecular Research Group, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom
    Clin Cancer Res 9:1361-9. 2003
  7. ncbi Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma
    Y Yokoyama
    Department of Obstetrics and Gynaecology, University of Cambridge, The Rose Maternity Hospital, UK
    Br J Cancer 88:237-44. 2003
  8. ncbi Alopecia related to low dose oral contraceptive
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 266:46-7. 2002
  9. ncbi Primary non-Hodgkin's lymphoma of the uterine cervix
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 265:108-11. 2001
  10. ncbi Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Amori, Japan
    Mol Cancer Ther 6:1379-86. 2007

Collaborators

Detail Information

Publications23

  1. ncbi Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancer
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 263:206-7. 2000
    ..We report a patient suffering from acute nonlymphocytic leukemia (ANLL) 3 years after treatment for stage IV ovarian cancer began...
  2. ncbi Clinical outcome and risk factors for recurrence in borderline ovarian tumours
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Br J Cancer 94:1586-91. 2006
    ..However, in cases of serous type and/or receiving cystectomy special care should be given as relative risk rates of recurrence elevate by 2-4-folds...
  3. ncbi A phase II multicenter trial of concurrent chemoradiotherapy with weekly nedaplatin in advanced uterine cervical carcinoma: Tohoku Gynecologic Cancer Unit Study
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Japan
    Oncol Rep 19:1551-6. 2008
    ..4%) and 1 (2.2%), respectively. These results indicate that weekly nedaplatin of 30 mg/m(2) with concurrent radiotherapy is an effective and well-tolerated regimen for advanced squamous cell carcinoma of the uterine cervix...
  4. ncbi Combination of ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, and cisplatin enhances the inhibition of growth of human ovarian cancers
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
    J Cancer Res Clin Oncol 137:1219-28. 2011
    ..In this study, we investigated the effects of combination of ciglitazone, a PPAR? ligand, and cisplatin, a cytotoxic anti-cancer drug, on growth of ovarian cancer...
  5. ncbi Asymptomatic intracardiac metastasis from a low-grade endometrial stromal sarcoma with successful surgical resection
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Gynecol Oncol 92:999-1001. 2004
    ..A case of a patient who successfully underwent surgical extraction of metastatic tumors of the low-grade ESS in the right ventricle is described in the present report...
  6. ncbi Expression of vascular endothelial growth factor (VEGF)-D and its receptor, VEGF receptor 3, as a prognostic factor in endometrial carcinoma
    Yoshihito Yokoyama
    Reproductive Molecular Research Group, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom
    Clin Cancer Res 9:1361-9. 2003
    ..To evaluate the prognostic value of vascular endothelial growth factor (VEGF)-D and VEGF receptor (VEGFR)-3 in endometrial carcinoma...
  7. ncbi Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma
    Y Yokoyama
    Department of Obstetrics and Gynaecology, University of Cambridge, The Rose Maternity Hospital, UK
    Br J Cancer 88:237-44. 2003
    ..Since VEGF-D was found to be an independent predictor of poor outcome, its measurement, together with other prognostic markers may improve prospective identification of patients with a poor prognosis...
  8. ncbi Alopecia related to low dose oral contraceptive
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 266:46-7. 2002
    ..Although LD-OC scarcely induce troublesome side effects if prescribed in accordance with Managing Contraceptive Pill Patients Guideline, this trouble might become a source of poor compliance to LD-OCs...
  9. ncbi Primary non-Hodgkin's lymphoma of the uterine cervix
    Y Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori, Japan
    Arch Gynecol Obstet 265:108-11. 2001
    ..She had a complete remission with a combination of chemotherapy and radiotherapy. Measurement of the serum soluble interleukin-2 receptor level was a useful index of the effectiveness of treatment...
  10. ncbi Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer
    Yoshihito Yokoyama
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Amori, Japan
    Mol Cancer Ther 6:1379-86. 2007
    ..We conclude that CA could be an effective agent in ovarian cancer and should be tested alone and in combination with other anticancer drugs...
  11. ncbi Peroxisome proliferator-activated receptor alpha and gamma ligands inhibit the growth of human ovarian cancer
    Tatsuhiko Shigeto
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Aomori 036 8562, Japan
    Oncol Rep 18:833-40. 2007
    ..These findings indicate that the combination of CA and pioglitazone produces a potent antitumor effect on ovarian cancer through reduction of AP-1 expression...
  12. ncbi Inhibitory effect of meloxicam, a selective cyclooxygenase-2 inhibitor, and ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, on the growth of human ovarian cancers
    Bing Xin
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Cancer 110:791-800. 2007
    ....
  13. ncbi Anti-tumor effect of non-steroidal anti-inflammatory drugs on human ovarian cancers
    Bing Xin
    Department of Obstetrics and Gynecology, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan
    Pathol Oncol Res 13:365-9. 2007
    ....
  14. ncbi Phase II clinical study of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of recurrent ovarian cancer (Tohoku Gynecologic Cancer Unit 101 Group Study)
    Tadahiro Shoji
    Department of Obstetrics and Gynecology, Iwate Medical University School of Medicine, Morioka, Japan
    Int J Gynecol Cancer 21:44-50. 2011
    ..To evaluate the efficacy and safety of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of patients with recurrent ovarian cancer after previous treatment with platinum and taxane agents...
  15. ncbi Para-aortic lymphadenectomy may improve disease-related survival in patients with multipositive pelvic lymph node stage IIIc endometrial cancer
    Toshio Fujimoto
    Department of Obstetrics and Gynecology, Akita University School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
    Gynecol Oncol 107:253-9. 2007
    ..The purpose of this study was to determine whether para-aortic lymphadenectomy improves disease-related survival (DRS) in stage IIIc endometrial cancer...
  16. ncbi Identifying prognostic factors in Japanese women with pseudomyxoma peritonei: a retrospective clinico-pathological study of the Tohoku Gynecologic Cancer Unit
    Takanobu Kojimahara
    Yamagata University School of Medicine, Department of Obstetrics and Gynecology, Yamagata, Japan
    Tohoku J Exp Med 223:91-6. 2011
    ..064). In conclusion, the macroscopic residual tumor is an important prognostic factor in Japanese patients with PMP...
  17. ncbi Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: carbonyl reductase predicts prognosis and lymph node metastasis
    Akihiro Murakami
    Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, 1 1 1 Minamikogushi, Ube 755 8505, Japan
    Cancer Lett 311:77-84. 2011
    ..This clinical result is supported by the in vitro data which show that suppression of CR expression promotes cancer cell invasion with decreased E-cadherin expression and increased MMP-2, -9 secretion...
  18. ncbi Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancers
    M Wakui
    Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
    J Cancer Res Clin Oncol 136:1143-50. 2010
    ....
  19. ncbi A case of uterine leiomyoma with intravenous leiomyomatosis--histological investigation of the pathological condition--
    Asami Fukuyama
    Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori 036 8562, Japan
    Pathol Oncol Res 17:171-4. 2011
    ....
  20. ncbi Malignant ovarian tumors with induced expression of carbonyl reductase show spontaneous regression
    Hui Wang
    Department of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu cho, Hirosaki, Aomori, 036 8562, Japan
    Clin Med Insights Oncol 6:107-15. 2012
    ..The present study investigated tumor proliferation in a tumor model using murine ovarian cancer cells with increased carbonyl reductase (CR) expression...
  21. ncbi Different susceptibility to peroxisome proliferator-induced hepatocarcinogenesis in rats with polymorphic glutathione transferase genes
    Toshihiro Kudo
    Second Department of Biochemistry, Hirosaki University School of Medicine, 5 Zaifu cho, Hirosaki 036 8562, Japan
    Cancer Sci 97:703-9. 2006
    ..These results indicate that rats that are polymorphic for the GST M1 gene exhibit different susceptibilities to CF in vivo...
  22. ncbi Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function
    Alexander G Marneros
    Department of Cell Biology, Harvard Medical School, 188 Longwood Ave, Boston, MA 02115, USA
    Am J Pathol 167:1451-9. 2005
    ..Thus, hypoxia-inducible factor-1alpha-independent expression of VEGF is essential for choroid development...
  23. ncbi [Mass-screening for ovarian cancer]
    Shigemi Sato
    Department of Obstetrics and Gynecology, Hirosaki City Hospital
    Nippon Rinsho 62:601-4. 2004