Research Topics
| Hiroaki YagiSummaryAffiliation: Hamamatsu University School of Medicine Country: Japan Publications
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Detail Information
Publications
Chemokine receptor expression in cutaneous T cell and NK/T-cell lymphomas: immunohistochemical staining and in vitro chemotactic assayHiroaki Yagi
Department of Dermatology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu, Japan
Am J Surg Pathol 30:1111-9. 2006..Therefore, spatial and temporal interactions between chemokine receptors and their ligands seem to dictate recruitment and retention of lymphoma cells in the skin...- Induction of therapeutically relevant cytotoxic T lymphocytes in humans by percutaneous peptide immunizationHiroaki Yagi
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
Cancer Res 66:10136-44. 2006..PPI elicited neither local nor systemic toxicity or autoimmunity, except for vitiligo, in patients with melanoma. Therefore, PPI represents a novel therapeutic intervention for cancer in the clinical setting... - Compartmental imbalance and aberrant immune function of blood CD123+ (plasmacytoid) and CD11c+ (myeloid) dendritic cells in atopic dermatitisHideo Hashizume
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
J Immunol 174:2396-403. 2005..Therefore, compartmental imbalance and aberrant immune function of the blood DC subsets may deviate the Th1/Th2 differentiation and thus induce protracted allergic responses in AD... - Combination therapy with oral PUVA and corticosteroid for recalcitrant alopecia areataTaisuke Ito
Department of Dermatology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Higashi ku, Hamamatsu 431 3192, Japan
Arch Dermatol Res 301:373-80. 2009..Taken together, the combination therapy may modify the systemic immune system and increase the number of Treg cells, resulting in improvement of recalcitrant AA... - Promiscuous interaction between gold-specific T cells and APCs in gold allergyHideo Hashizume
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
J Immunol 181:8096-102. 2008..These observations raise the possibility that gold-specific CD4(+) and CD8(+) T cells and APCs promiscuously interact under stimulation with gold, resulting in various clinical manifestations in gold allergy... - Efficacy and safety of preprandial versus postprandial administration of low-dose cyclosporin microemulsion (Neoral) in patients with psoriasis vulgarisHideo Hashizume
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
J Dermatol 34:430-4. 2007..Short-term, low-dose treatment with cyclosporin before rather than after meals is suggested as a new effective treatment regimen for psoriasis, with the added advantage of lowering costs... - Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma with a CD15(+)CD30(-) phenotypeNaho Yoshizawa
Department of Dermatology, Shizuoka Municipal Shimizu Hospital, 1231 Miyakami Shimizu, Shizuoka 424 8636, Japan
Eur J Dermatol 17:441-2. 2007.... - Roxithromycin antagonizes catagen induction in murine and human hair follicles: implication of topical roxithromycin as hair restoration reagentTaisuke Ito
Department of Dermatology, Hamamatsu University School of Medicine, 1 20 1 Handayama Higashi ku, Hamamatsu 431 3192, Japan
Arch Dermatol Res 301:347-55. 2009..Furthermore, topical 5% RXM solution effectively restores hair growth in about half of individuals with AGA without any local and systemic adverse effects. Therefore, RXM is new candidate as a hair restoration drug for AGA... - Intestinal Behcet's disease with pyoderma gangrenosum: a case reportToshio Nakamura
The Second Department of Surgery, Hamamatsu University School of Medicine, 1 20 1 Handa yama, Hamamatsu 431 3192, Japan
World J Gastroenterol 12:979-81. 2006..Subsequently, pyoderma gangrenosum rapidly improved. This clinical course may suggest the close relationship between pyoderma gangrenosum and intestinal Behcet's disease... - Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanomaRyosuke Hino
Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan
Cancer 116:1757-66. 2010..To investigate the mechanism underlining the immunosuppression of melanoma patients, the authors focused on programmed cell death-1 (PD-1)/PD-1 ligand 1 (PD-L1) interaction between tumor cells and T cells... - Cutaneous type of adult T cell leukemia/lymphoma: a new entity among cutaneous lymphomasHiroaki Yagi
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
J Dermatol 30:641-3. 2003..The presence of monoclonal integration of human T lymphotropic virus-I proviral DNA in skin samples is of definitive diagnostic value in cutaneous ATL... - Unique therapeutic effects of the Japanese-Chinese herbal medicine, Sairei-to, on Th1/Th2 cytokines balance of the autoimmunity of MRL/lpr miceTaisuke Ito
Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan
J Dermatol Sci 28:198-210. 2002..On the other hand, Th2 cell type immunoglobulins (IgG1) were suppressed. These results suggested that Sairei-to is potential for impairing shifted Th1/Th2 balance and hypergammaglobulinemia resulting in therapeutic effects... - Primary cutaneous anaplastic large cell lymphoma with fatal leukemic outcome in association with CLA and CCR4-negative conversionYoshiki Tokura
Department of Dermatology at the University of Occupational and Environmental Health, Kitakyushu, Japan
J Am Acad Dermatol 57:S92-6. 2007..The altered expression of skin-homing receptors might change its clinical behavior... - Treatment of titanium dental implants with three piezoelectric ultrasonic scalers: an in vivo studyHideyuki Kawashima
Department of Periodontology, Nihon University School of Dentistry, Tokyo, Japan
J Periodontol 78:1689-94. 2007..Some ultrasonic scalers may be useful for implant maintenance; however, no clinical study has examined this. This study evaluated the treatment of titanium implants with three piezoelectric scalers in vivo... - Palpable archiform migratory erythema preceded by B-cell pseudolymphoma in a Japanese manHiroaki Yagi
Acta Derm Venereol 88:171-2. 2008 - Alopecia universalis associated with impaired interleukin-4 production and low serum IgE levelYoshiki Tokura
Department of Dermatology at the University of Occupational and Environmental Health, Kitakyushu, Japan
J Am Acad Dermatol 57:S22-5. 2007..The autoimmune hair loss might occur via activation of cytotoxic T cells and Th(1) cells as a result of a relief from IL-4 control...