Research Topics
| Chiyoji AbeSummaryAffiliation: Graduate School Country: Japan Publications
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Detail Information
Publications
Biological and molecular characteristics of Mycobacterium tuberculosis clinical isolates with low-level resistance to isoniazid in JapanChiyoji Abe
Fukushima Laboratory, Nippon Becton Dickinson Diagnostic Systems, Tsuchifune, Fukushima 960 2152, Japan
J Clin Microbiol 46:2263-8. 2008..In addition, the analyses demonstrated some relationship of mutations in the inhA gene with ethionamide resistance for the Low-S strains, but not for the High-R strains...
[Standardization of laboratory tests for tuberculosis and their proficiency testing]Chiyoji Abe
Kekkaku 78:541-51. 2003..For isoniazid and rifampin, sensitivity has been consistently high since the beginning of the Global Project. This indeed reflects the enhanced efforts made by the SRLs to improve their individual performance...
Evaluation of BACTEC MGIT 960 PZA medium for susceptibility testing of Mycobacterium tuberculosis to pyrazinamide (PZA): compared with the results of pyrazinamidase assay and Kyokuto PZA testAkio Aono
Department of Clinical Laboratory, Fukujuji Hospital, Kiyose-shi, Tokyo 204-8533, Japan
Diagn Microbiol Infect Dis 44:347-52. 2002..These results indicate that both methods based on liquid media, the fully automated BACTEC MGIT 960 PZA medium and the Kyokuto PZA test for susceptibility testing to PZA, are useful for rapid diagnosis of PZA resistant tuberculosis...
[Comparative study of bactec MGIT 960 AST and conventional proportion method using Ogawa medium for the drug susceptibility testing of Mycobacterium tuberculosis to isoniazid]Satoshi Mitarai
Bacteriology Division, Mycobacterium Reference Centre, Research Institute of Tuberculosis, JATA, 3 1 24 Matsuyama, Kiyose shi, Tokyo 204 8533, Japan
Kekkaku 82:449-54. 2007..To evaluate the accuracy of drug susceptibility testing to isoniazid with BACTEC MGIT 960 (MGIT AST) comparing with the standard proportion method using Ogawa medium...
[BACTEC MGIT 960 system for drug susceptibility testing of Mycobacterium tuberculosis: a study using external quality assessment strains]Ikuo Kobayashi
Nippon Becton Dickinson Company, Ltd, 1 Gotanda, Tsuchifune, Fukushima shi, Fukushima 960 2152 Japan
Kekkaku 81:57-62. 2006..To evaluate the performance of the BACTEC MGIT 960 system for drug susceptibility testing (MGIT AST) of Mycobacterium tuberculosis to isoniazid, rifampin, streptomycin and ethambutol...
Simple fibroblast-based assay to test the pyrazinamide susceptibility of Mycobacterium tuberculosisTakemasa Takii
Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
Antimicrob Agents Chemother 49:804-7. 2005..Forty-five clinical isolates were examined. The MICs of PZA for susceptible strains in an SFA were between 3.13 and 12.5 microg/ml, and the MICs of PZA for resistant strains were more than 100 microg/ml...
Mutations including IS6110 insertion in the gene encoding the MPB64 protein of Capilia TB-negative Mycobacterium tuberculosis isolatesKazue Hirano
Department of Basic Research, Research Institute of Tuberculosis, Fukujuji Hospital, Kiyose shi, Tokyo 204 8533, Japan
J Clin Microbiol 42:390-2. 2004..The sequencing analysis revealed that all of the Capilia TB-negative isolates had mutations within the mpb64 gene, leading to the production of an incomplete protein as a result of a deletion of the C-terminal region of the protein...
Simple fibroblast-based assay for screening of new antimicrobial drugs against Mycobacterium tuberculosisTakemasa Takii
Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3 1 Tanabe dori, Mizuho ku, Nagoya 467 8603, Japan
Antimicrob Agents Chemother 46:2533-9. 2002..Thus, this fibroblast-based method enabled us to evaluate both antibacterial activity of drugs and their cytotoxicity to human cells within a short period of time...
[Ogawa's method for isolation and culturing mycobacterial organisms]Chiyoji Abe
Nihon Kokyuki Gakkai Zasshi . 2003
[Comparative genomics of Mycobacterium tuberculosis and M. leprae]Chiyoji Abe
Department of Basic Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association
Nippon Rinsho 61:753-8. 2003
[Multidrug-resistant tuberculosis]Chiyoji Abe
Department of Basic Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association
Nippon Rinsho 61:202-6. 2003
Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureusTaku Chiba
Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
Bioorg Med Chem Lett 17:2487-91. 2007..The allyl group at C-1 and the acetoxy groups of the manninotrioside were requisite for the antibacterial activity...
Evaluation of major membrane protein-II as a tool for serodiagnosis of leprosyYumi Maeda
Department of Microbiology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan
FEMS Microbiol Lett 272:202-5. 2007..These percentage values were significantly higher than these values obtained for existing phenolic glycolipid-I based methods, suggesting that MMP-II antibody detection would facilitate the diagnosis of leprosy...
Heterogeneity of RNA polymerase gene (rpoB) sequences of Mycobacterium gordonae clinical isolates identified with a DNA probe kit and by conventional methodsSaotomo Itoh
Bacteriology Division, The Research Institute of Tuberculosis, Japan Antituberculosis Association, Kiyose-shi, Tokyo 204-8533, Japan
J Clin Microbiol 41:1656-63. 2003..gordonae-like cluster may help to establish the comparison between the M. gordonae isolates from a clinical specimen and an infectious process in a given patient and to determine the true incidence of infection with this microorganism...
rpoB genotypes of Mycobacterium tuberculosis Beijing family isolates from East Asian countriesLishi Qian
Department of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
J Clin Microbiol 40:1091-4. 2002..5%, respectively) and His-526 (12 and 6.3%, respectively). The different rates of mutation may reflect the choice of rifamycin analogs...
