Research Topics
| Minoru OnozukaSummaryAffiliation: Gifu University Country: Japan Publications
| Collaborators
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Detail Information
Publications
Reduced mastication stimulates impairment of spatial memory and degeneration of hippocampal neurons in aged SAMP8 miceM Onozuka
Department of Anatomy, 2nd Division, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu, 500 8705, Japan
Brain Res 826:148-53. 1999..These changes increased the longer the molarless condition persisted. The data suggest a possible link between reduced mastication and hippocampal neuron loss that may be one risk factor for senile impairment of spatial memory...- Age-related changes in brain regional activity during chewing: a functional magnetic resonance imaging studyM Onozuka
Department of Anatomy and Basic Neuroscience, Gifu University School of Medicine, Japan
J Dent Res 82:657-60. 2003..The remaining two regions showed no significant differences with ages. These results indicate that chewing causes regional increases in neuronal activity in the brain, some of which are age-dependent... - Mapping brain region activity during chewing: a functional magnetic resonance imaging studyM Onozuka
Department of Anatomy and Basic Neuroscience, Gifu University School of Medicine, Japan
J Dent Res 81:743-6. 2002..However, the signal was higher in the cerebellum and not significant in the thalamus, respectively. These results suggest that chewing causes regional increases in brain neuronal activities which are related to biting force... - Changes in the septohippocampal cholinergic system following removal of molar teeth in the aged SAMP8 mouseMinoru Onozuka
Department of Anatomy 2nd Division, Gifu University School of Medicine, 40 Tsukasa Machi, Japan
Behav Brain Res 133:197-204. 2002..The results suggest that the molarless condition in aged SAMP8 mice may enhance an age-related decline in the septohippocampal cholinergic system... - Evidence for involvement of glucocorticoid response in the hippocampal changes in aged molarless SAMP8 miceMinoru Onozuka
Department of Anatomy 2nd Division, School of Medicine, Gifu University, 40 Tsukasa Machi, 500 8705, Gifu, Japan
Behav Brain Res 131:125-9. 2002..The results suggest a link between the molarless condition and the glucocorticoid response, which may be involved in spatial learning deficits and hippocampal neuronal death in aged SAMP8 mice... - Impairment of spatial memory and changes in astroglial responsiveness following loss of molar teeth in aged SAMP8 miceM Onozuka
Department of Anatomy, Gifu University School of Medicine, Japan
Behav Brain Res 108:145-55. 2000..The data suggest that an impairment of spatial memory and changes in astroglial responsiveness occur following the loss of molar teeth in aged SAMP8 mice... - Optimal scan delays for multiphasic renal multidetector row computed tomography performed with fixed injection duration of contrast mediumYusuke Tsuge
Department of Radiology, Gifu University School of Medicine, Gifu University Hospital, Gifu, Japan
J Comput Assist Tomogr 33:101-5. 2009..The purpose of our study was to prospectively determine optimal scan delays for multiphasic imaging of the kidney performed with multidetector row computed tomography (CT) and fixed injection duration of intravenous contrast medium... - MDCT of the pancreas: optimizing scanning delay with a bolus-tracking technique for pancreatic, peripancreatic vascular, and hepatic contrast enhancementHiroshi Kondo
Department of Radiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
AJR Am J Roentgenol 188:751-6. 2007..The purpose of this study was to determine the optimal MDCT scanning delay for peripancreatic arterial, pancreatic parenchymal, peripancreatic venous, and hepatic parenchymal contrast enhancement with a bolus-tracking technique... - Diffusion-weighted imaging of the liver: optimizing b value for the detection and characterization of benign and malignant hepatic lesionsSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, Gifu University Hospital, Gifu, Japan
J Magn Reson Imaging 28:691-7. 2008..To determine the optimal b values required for diffusion-weighted (DW) imaging of the liver in the detection and characterization of benign and malignant hepatic lesions... - Hepatic hemangioma: correlation of enhancement types with diffusion-weighted MR findings and apparent diffusion coefficientsSatoshi Goshima
Department of Radiology, Gifu University Hospital, Gifu, Japan
Eur J Radiol 70:325-30. 2009..To correlate hepatic hemangioma enhancement types in gadolinium-enhanced magnetic resonance (MR) images with diffusion-weighted MR findings and apparent diffusion coefficients (ADCs)... - Multi-detector row CT of the kidney: optimizing scan delays for bolus tracking techniques of arterial, corticomedullary, and nephrographic phasesSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1193, Japan
Eur J Radiol 63:420-6. 2007..To determine optimal scan delays for renal arterial-, corticomedullary-, and nephrographic-phase imaging with multi-detector row computed tomography (MDCT) of the kidney using a bolus-tracking technique... - MDCT of the liver and hypervascular hepatocellular carcinomas: optimizing scan delays for bolus-tracking techniques of hepatic arterial and portal venous phasesSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1194, Japan
AJR Am J Roentgenol 187:W25-32. 2006.... - Detection and grading for esophageal varices in patients with chronic liver damage: comparison of gadolinium-enhanced and unenhanced steady-state coherent MR imagesSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1193, Japan
Magn Reson Imaging 27:1230-5. 2009..Nevertheless, endoscopy was confirmed to be mandatory in patients with esophageal varices suspected by MRI of the liver... - Abdominal multidetector CT in patients with varying body fat percentages: estimation of optimal contrast material doseHiroshi Kondo
Department of Radiology, Kizawa Memorial Hospital, Gifu, Japan
Radiology 249:872-7. 2008..To determine if contrast material dose for abdominal multidetector computed tomography (CT), as determined by using body weight (BW), overestimates the amount of contrast material required in heavier patients... - The molarless condition in aged SAMP8 mice attenuates hippocampal Fos induction linked to water maze performanceKazuko Watanabe
Department of Physiology, Gifu University School of Medicine, Gifu 500 8705, Japan
Behav Brain Res 128:19-25. 2002..Gerontol. 2001; 36:283-95], the present results suggest the detrimental effects of a reduction in chewing on hippocampal processing in aged SAMP8 mice that would be linked with stress induced by the molarless condition... - Evaluating local hepatocellular carcinoma recurrence post-transcatheter arterial chemoembolization: is diffusion-weighted MRI reliable as an indicator?Satoshi Goshima
Department of Radiology, Gifu University Hospital, Gifu, Japan
J Magn Reson Imaging 27:834-9. 2008..To evaluate the detectability of local hepatocellular carcinoma (HCC) recurrence after transcatheter arterial chemoembolization (TACE) by diffusion-weighted MR imaging in correlation with those of gadolinium-enhanced MR imaging... - Preoperative T staging of urinary bladder cancer: does diffusion-weighted MRI have supplementary value?Haruo Watanabe
Department of Radiology, Gifu University Hospital, 1 1 Yanagido, Gifu, Japan
AJR Am J Roentgenol 192:1361-6. 2009..The objective of our study was to evaluate whether diffusion-weighted MRI has supplementary value in the preoperative T staging of urinary bladder cancer... - CT of the pancreas: comparison of anatomic structure depiction, image quality, and radiation exposure between 320-detector volumetric images and 64-detector helical imagesSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, 1 1 Yanagido, Gifu 501 1193, Japan
Radiology 260:139-47. 2011..To prospectively compare 320-detector volumetric and 64-detector helical computed tomographic (CT) images of the pancreas for depiction of anatomic structures, image noise, and radiation exposure... - Pancreas: optimal scan delay for contrast-enhanced multi-detector row CTSatoshi Goshima
Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1193, Japan
Radiology 241:167-74. 2006.... - Gadolinium-enhanced multiphasic 3D MRI of the liver with prospective adaptive navigator correction: phantom study and preliminary clinical evaluationMasayuki Kanematsu
Radiology Services, Gifu University Hospital, 1 1 Yanagido, Gifu, Gifu, Japan 501 1194
AJR Am J Roentgenol 188:W309-16. 2007.... - Projections of glutamate decarboxylase positive and negative cerebellar neurons to the pretectum in the catHiroyuki Nakamura
Department of Morphological Neuroscience, Gifu University Graduate School of Medicine, Yanagido 1 1, Gifu 501 1194, Japan
Neurosci Lett 403:30-4. 2006..Our findings thus suggest the existence of two distinct cerebello-pretectal projection systems: one is mediated by GABAergic inhibitory projections, while the other is mediated by non-GABAergic, probably glutamatergic excitatory ones... - Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathwayYoshiko Banno
Department of Cell Signaling, Gifu University Graduate School of Medicine, Gifu, Japan
J Neurochem 104:1372-86. 2008..This is the first demonstration that PLD2 activation is involved in GAP-43 and synapsin I expression during depolarization-induced neuronal differentiation in PC12 cells... - Ventral lateral geniculate nucleus projects to the dorsal lateral geniculate nucleus in the catHiroyuki Nakamura
Department of Morphological Neuroscience, Division of Neuroscience, Gifu University Graduate School of Medicine, Gifu, Japan
Neuroreport 16:1575-8. 2005.... - Gender-related changes in three-dimensional microstructure of trabecular bone at the human proximal tibia with agingHuayue Chen
Department of Anatomy, Gifu University Graduate School of Medicine, Gifu, Japan
Histol Histopathol 26:563-70. 2011..These findings illustrate potential mechanisms underlying osteoporotic proximal tibial fracture... - Optimizing scan delays of fixed duration contrast injection in contrast-enhanced biphasic multidetector-row CT for the liver and the detection of hypervascular hepatocellular carcinomaMasayuki Kanematsu
Department of Radiology, Gifu University School of Medicine, Gifu, Japan
J Comput Assist Tomogr 29:195-201. 2005..To determine the optimal scan delay required for fixed duration contrast injection in contrast-enhanced biphasic multidetector-row CT for the liver and the detection of hypervascular hepatocellular carcinoma (HCC)... - The bite-raised condition in aged SAMP8 mice induces dendritic spine changes in the hippocampal regionKin ya Kubo
Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu 501 0296, Japan
Neurosci Lett 441:141-4. 2008..The results suggest that the bite-raised condition exacerbates the age-related spatial learning impairment, and that this may be due to the degeneration of hippocampal dendritic spines... - Occlusal disharmony attenuates glucocorticoid negative feedback in aged SAMP8 miceYukiko Ichihashi
Department of Pediatric Dentistry, Asahi University School of Dentistry, Mizuho, Japan
Neurosci Lett 427:71-6. 2007..These findings suggest that the bite-raised condition in aged SAMP8 mice decreases GR and GRmRNA, which impairs the hypothalamic-pituitary-adrenal feedback inhibition, thereby leading to memory deficits... - Effects of chewing in working memory processingYoshiyuki Hirano
Department of Biophysics, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan
Neurosci Lett 436:189-92. 2008..These results suggest that chewing may accelerate or recover the process of working memory besides inducing improvement in the arousal level by the chewing motion... - Effect of unpleasant loud noise on hippocampal activities during picture encoding: an fMRI studyYoshiyuki Hirano
Department of Physiology and Neuroscience, Kanagawa Dental College, Yokosuka 238 8580, Japan
Brain Cogn 61:280-5. 2006..Therefore, noise should diminish memory by reducing hippocampal activity, which might be depressed by high amygdala activity... - Occlusal disharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 miceKin ya Kubo
Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
Neurosci Lett 414:188-91. 2007..The findings suggest that the bite-raised condition in aged SAMP8 mice induces hippocampal neuron loss, thereby leading to senile memory deficits... - Molarless-induced changes of spines in hippocampal region of SAMP8 miceKin ya Kubo
Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
Brain Res 1057:191-5. 2005..The results suggest the involvement of the molarless condition in an attenuation of input activities in the hippocampal synapses... - Abdomen: angiography with 16-detector CT--comparison of image quality and radiation dose between studies with 0.625-mm and those with 1.25-mm collimationToshiharu Miyoshi
Radiology Services, Gifu University Hospital, 1 1 Yanagido, 501 1194 Gifu, Japan
Radiology 249:142-50. 2008..To prospectively compare image quality and volume computed tomographic (CT) dose index (CTDI(vol)) of 16-detector CT angiograms of the abdomen acquired with 0.625-mm collimation with those of images acquired with 1.25-mm collimation...