S Kunishima

Summary

Affiliation: Fujita Health University
Country: Japan

Publications

  1. ncbi Platelet glycoprotein (GP) V polymorphisms in Japanese
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto
    Tissue Antigens 54:285-7. 1999
  2. ncbi Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome
    S Kunishima
    Japanese Red Cross Aichi Blood Centre, Seto, Aichi, Japan
    Br J Haematol 107:539-45. 1999
  3. ncbi Homozygous Pro74-->Arg mutation in the platelet glycoprotein Ibbeta gene associated with Bernard-Soulier syndrome
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Thromb Haemost 84:112-7. 2000
  4. ncbi Novel heterozygous missense mutation in the platelet glycoprotein Ib beta gene associated with isolated giant platelet disorder
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Am J Hematol 68:249-55. 2001
  5. ncbi Expression of low-frequency Ala108Pro substitution in the platelet glycoprotein Ibbeta gene
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Eur J Immunogenet 30:159-61. 2003
  6. ncbi Presence of Propionibacterium acnes in blood components
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Minamiyamaguchi, Seto, Japan
    Transfusion 41:1126-9. 2001
  7. ncbi A new polymorphism in the HLA-F gene (67Ala[GCC] to Ala[GCG])
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Immunogenetics 49:147-8. 1999
  8. ncbi A missense mutation (Tyr88 to Cys) in the platelet membrane glycoprotein Ibbeta gene affects GPIb/IX complex expression--Bernard-Soulier syndrome in the homozygous form and giant platelets in the heterozygous form
    Y Kurokawa
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Thromb Haemost 86:1249-56. 2001
  9. ncbi Missense mutations of the glycoprotein (GP) Ib beta gene impairing the GPIb alpha/beta disulfide linkage in a family with giant platelet disorder
    S Kunishima
    Department of Medicine, Nagoya University Branch Hospital, Higashi ku, Japan
    Blood 89:2404-12. 1997
  10. ncbi Giant platelet syndrome
    H Saito
    Nagoya Medical Center and Nagoya University School of Medicine, Nagoya, Japan
    Hematology 10:41-6. 2005

Collaborators

Detail Information

Publications10

  1. ncbi Platelet glycoprotein (GP) V polymorphisms in Japanese
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto
    Tissue Antigens 54:285-7. 1999
    ..Flow cytometric analysis showed that the 341Arg variant is expressed normally on the platelet membranes, suggesting the possibility of the involvement of the 341Gly/Arg polymorphism as a platelet alloantigen...
  2. ncbi Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome
    S Kunishima
    Japanese Red Cross Aichi Blood Centre, Seto, Aichi, Japan
    Br J Haematol 107:539-45. 1999
    ..Transient transfection studies confirmed that mutant GPIX was not expressed on the transfected cells, showing that the mutation was responsible for the BSS phenotype observed in the patient...
  3. ncbi Homozygous Pro74-->Arg mutation in the platelet glycoprotein Ibbeta gene associated with Bernard-Soulier syndrome
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Thromb Haemost 84:112-7. 2000
    ..The mutant GPIbbeta was normally transcribed. Transient transfection studies confirmed that mutant GPIbbeta impairs surface expression of GPIb/IX, showing that the mutation is responsible for a BSS phenotype observed in the patient...
  4. ncbi Novel heterozygous missense mutation in the platelet glycoprotein Ib beta gene associated with isolated giant platelet disorder
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Am J Hematol 68:249-55. 2001
    ....
  5. ncbi Expression of low-frequency Ala108Pro substitution in the platelet glycoprotein Ibbeta gene
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Eur J Immunogenet 30:159-61. 2003
    ..In vitro expression studies showed surface expression of the GPIbbeta Pro108 variant, suggesting the possibility of the involvement of the substitution as an alloantigen...
  6. ncbi Presence of Propionibacterium acnes in blood components
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Minamiyamaguchi, Seto, Japan
    Transfusion 41:1126-9. 2001
    ..18%), all of which were RBC concentrates, were contaminated with bacteria. Nine isolates were Propionibacterium acnes and one was Staphylococcus capitis...
  7. ncbi A new polymorphism in the HLA-F gene (67Ala[GCC] to Ala[GCG])
    S Kunishima
    Japanese Red Cross Aichi Blood Center, Seto, Japan
    Immunogenetics 49:147-8. 1999
  8. ncbi A missense mutation (Tyr88 to Cys) in the platelet membrane glycoprotein Ibbeta gene affects GPIb/IX complex expression--Bernard-Soulier syndrome in the homozygous form and giant platelets in the heterozygous form
    Y Kurokawa
    Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan
    Thromb Haemost 86:1249-56. 2001
    ..Tyr88 in the GPIbbeta gene plays a significant role in the GPIb/IX expression; the defect causes BSS in a homozygous form and possibly giant platelets in a heterozygous form...
  9. ncbi Missense mutations of the glycoprotein (GP) Ib beta gene impairing the GPIb alpha/beta disulfide linkage in a family with giant platelet disorder
    S Kunishima
    Department of Medicine, Nagoya University Branch Hospital, Higashi ku, Japan
    Blood 89:2404-12. 1997
    ..Furthermore, the phenotype caused by mutations in the subunits of the GPIb/IX complex could span the spectrum from a normal phenotype, to isolated GPD, to a full-blown bleeding disorder, such as Bernard-Soulier syndrome...
  10. ncbi Giant platelet syndrome
    H Saito
    Nagoya Medical Center and Nagoya University School of Medicine, Nagoya, Japan
    Hematology 10:41-6. 2005