Research Topics
| T EnomotoSummaryCountry: Japan Publications
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Detail Information
Publications
Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unitT Enomoto
Division of Otolaryngology Head and Neck Surgery, Department of Medicine of Sensory and Motor Organs, Tottori University Faculty of Medicine, Tottori, Japan
J Investig Allergol Clin Immunol 19:299-305. 2009..Second-generation oral H1-antihistamines have become a mainstay of treatment for the symptoms of seasonal allergic rhinitis; however, the effect of olopatadine has not been widely reported to date...
[A case presenting anaphylaxis shock after intake of capsule packing cedar pollen]Tadao Enomoto
NPO Japan Health Promotion Supporting Network
Arerugi 58:39-44. 2009..In conclusion, it is appropriate to consider it exercise induce anaphylaxis shock due to playing tennis after intake of the capsular...
Construction of an environmental exposure unit and investigation of the effects of cetirizine hydrochloride on symptoms of cedar pollinosis in JapanT Enomoto
Department of Otolaryngology, Red Cross Society, Wakayama Medical Center, Wakayama City, Japan
J Investig Allergol Clin Immunol 17:173-81. 2007..Environmental exposure units (EEU) assist in the development of effective therapeutic and preventive measures because outdoor studies are limited by seasonal variation in pollen exposure...
[Early treatment for pollinosis]Tadao Enomoto
Department of Otolaryngology, Japanese Red Cross Society Wakayama Medical Center
Arerugi 52:1048-52. 2003
[Suppression of allergy development by habitual intake of fermented milk foods, evidence from an epidemiological study]Tadao Enomoto
Department of Otolaryngology, Japanese Red Cross Society Wakayama Medical Center
Arerugi 55:1394-9. 2006..The interest in anti-allergic immunoregulation by lactic acid bacteria (LAB) has been growing over the last few decades. However, little is known about the effect of habitually intake of fermented milk on allergy development...
[Japanese cedar pollen in house dust]T Enomoto
Department of Otolaryngology, Japanese Red Cross Society Wakayama Medical Center
Arerugi 50:535-9. 2001..The highest number of pollen found in one week was approximately 450 pollens in a square meter of a living room floor. The study concluded that cleaning is one of the best way to remove Japanese cedar pollens found in indoor dust...
Clinical effects of apple polyphenols on persistent allergic rhinitis: A randomized double-blind placebo-controlled parallel arm studyT Enomoto
Department of Otolaryngology, Japanese Red Cross Society, Wakayama Medical Center, Wakayama, Japan
J Investig Allergol Clin Immunol 16:283-9. 2006..CONCLUSIONS: We conclude that apple polyphenols are effective in alleviating symptoms of persistent allergic rhinitis...
Effect of antihistamine eye drops on the conjunctival provocation test with Japanese cedar pollen allergenYoshihiro Dake
Department of Otolaryngology, Japanese Red Cross Society, Wakayama Medical Center, Wakayama City, Japan
Allergol Int 55:373-8. 2006..No study has reported symptoms and their clinical courses after conjunctival provocation with purified cedar pollen allergen Cry j1 as well as suppression of these allergen-induced ocular symptoms by antihistamine eye drops...
Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unitJin Zhong Xiao
Food Research and Development Laboratory, Morinaga Milk Industry Co, Ltd, Kanagawa, Japan
Allergol Int 56:67-75. 2007..Japanese cedar pollinosis (JCPsis) affects nearly one in six Japanese. Oral administration of Bifidobacterium longum BB536 has been shown to be effective in relieving JCPsis symptoms during the pollen season...
[Epidemic study of pet allergy in Wakayama Prefecture]Satoshi Seno
Department of Otolaryngology, Head and Neck Surgery, Shiga University of Medical Science, Otsu
Nippon Jibiinkoka Gakkai Kaiho 106:750-3. 2003..2% for cats). Specific dog and cat IgE antibodies increased significantly (p = 0.033 for dog and for p < 0.0001 cat), but no significant correlation was found between the positive specific IgE antibody and history of pet keeping...
[Epidemiological survey of allergic diseases in first-year junior high school students in Wakayama Prefecture in 2003]Shigetoshi Yoda
Department of Otolaryngology, Japanese Red Cross Society, Wakayama Medical Center, Wakayama
Nippon Jibiinkoka Gakkai Kaiho 109:742-8. 2006..The findings of this epidemiologic study will contribute to basic data on the increasing prevalence of various allergic diseases...
Association between IFNA genotype and the risk of sarcoidosisMitsuteru Akahoshi
Laboratory for Genetics of Allergic Diseases, SNP Research Center, Institute of Physical and Chemical Research, RIKEN Yokohama Institute, Yokohama, Japan
Hum Genet 114:503-9. 2004..This study suggests that possession of the IFNA allele with higher levels of IFN-alpha significantly increases the risk of sarcoidosis...
An evaluation of the clinical efficacy of tomato extract for perennial allergic rhinitisMineka Yoshimura
Research and Development Division, Kikkoman Corporation, Chiba, Japan
Allergol Int 56:225-30. 2007..We have reported that tomato extract (TE) could possibly inhibit histamine release and mouse ear-swelling responses. Moreover, it is reported that TE could relieve the symptoms for Japanese cedar pollinosis...
Changes in plasma TARC levels during Japanese cedar pollen season and relationships with symptom developmentJin Zhong Xiao
Food Research and Development Laboratory, Morinaga Milk Industry, Zama, Japan
Int Arch Allergy Immunol 144:123-7. 2007..The present study aims to evaluate the relationship between TARC levels and disease symptoms during the pollen season...
The GSTP1 gene is a susceptibility gene for childhood asthma and the GSTM1 gene is a modifier of the GSTP1 geneFumiaki Kamada
Department of Medical Genetics, Tohoku University School of Medicine, Sendai, Japan
Int Arch Allergy Immunol 144:275-86. 2007..Several studies have shown that the GSTP1 geneis involved in the pathogenesis of asthma and a gene-gene interaction may occur within the GST gene superfamily...
Clinical effects of a hop water extract on Japanese cedar pollinosis during the pollen season: a double-blind, placebo-controlled trialShuichi Segawa
Frontier Laboratories of Value Creation, Sapporo Breweries Ltd, Yaizu, Shizuoka, Japan
Biosci Biotechnol Biochem 71:1955-62. 2007..These findings indicate that an oral administration of HWE may be effective in alleviating the allergic symptoms related to JCPsis...
Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen seasonToshitaka Odamaki
Food Research and Development Laboratory Morinaga Milk Industry Co Ltd, Zama, Kanagawa 228 8583, Japan
J Med Microbiol 56:1301-8. 2007..05). These results suggest that faecal microbiota in JCPsis subjects, but not healthy subjects, fluctuate at the end of the pollen season and that BB536 intake plays a role in maintaining normal microbiota...
Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese populationTomomitsu Hirota
J Allergy Clin Immunol 121:769-70. 2008
[2001 survey of pollen in Wakayama City with a real-time pollen counter]Satoshi Seno
Department of Otolaryngology, Japanese Red Cross Society, Wakayama Medical Center, Wakayama
Nippon Jibiinkoka Gakkai Kaiho 105:232-9. 2002..We have taken measure against snow, so we concluded that the real-time pollen counter was useful in counting the amount of airborne pollen over time...
[Willingness to pay for Japanese cedar pollinosis: comparison between pollination and non-pollination seasons]Chieko Kakutani
School of Allied Health Sciences, Faculty of Medicine, Osaka University
Arerugi 53:589-95. 2004..Decline in WTP for JCP in 2003 was strongly affected by Japanese sluggish economy, and the WTP seemed to be stable value in individual patients...
Association of the RIP2 gene with childhood atopic asthmaKazuko Nakashima
Laboratory for Genetics of Allergic Diseases, SNP Research Center, RIKEN, Kanagawa, Japan
Allergol Int 55:77-83. 2006..The aim of our study was to examine whether polymorphisms or haplotypes in RIP2 were associated with childhood atopic asthma in a Japanese population...
[Comparison of clinical efficacy and cost-quality of antihistamines in early treatment for Japanese cedar pollinosis]Chieko Kakutani
School of Allied Health Sciences, Faculty of Medicine, Osaka University
Arerugi 55:554-65. 2006..But Japanese National Health Insurance drug price scheme led to significant differences in cost-quality...
[Reevaluation of hygiene theory]Tadao Enomoto
Department of Otolaryngology Japanese Red Cross Society, Wakayama Medical Center
Arerugi 53:465-8. 2004
[Effects of drug adherence on patient outcomes to early treatment for Japanese cedar pollinosis]Chieko Kakutani
School of Allied Health Sciences, Faculty of Medicine, Osaka University
Arerugi 53:669-75. 2004..006), and short-duration of medication (p=0.001). Low costs were also risk factor for low adherence. We conclude that taking medications for JCP for 22-28 days is the best way to enhance patients' outcomes...
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthmaMitsuteru Akahoshi
Laboratory for Genetics of Allergic Diseases, SNP Research Center, RIKEN Yokohama Institute, Institute of Physical and Chemical Research RIKEN, Tsurumi ku, Kanagawa, Japan
Hum Genet 117:16-26. 2005....
[Genetic analysis of atopic diseases]Lei Cheng
Department of Health Promotion and Human Behaviour, Kyoto University Graduate School of Public Health, Japan
Nippon Rinsho 63:7-14. 2005
Coding SNP in tenascin-C Fn-III-D domain associates with adult asthmaAkira Matsuda
Laboratory for Genetics of Allergic Diseases, SNP Research Center, RIKEN, Yokohama, Japan
Hum Mol Genet 14:2779-86. 2005..In addition, TNC expression in lung fibroblasts increases with Th2 immune cytokine stimulation. Thus, Leu1677Ile may be valuable marker for evaluating the risk for developing asthma and plays a role in its pathogenesis...
[Regional comparison of patient-reported outcomes in Japanese cedar pollinosis]Chieko Kakutani
School of Allied Health Sciences, Faculty of Medicine, Osaka University
Arerugi 54:541-50. 2005..In patients with early treatment, however, the treatment duration had bigger impact on PROs than the local pollen counts...
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypesNaomi Takahashi
Laboratory of Genetics of Allergic Diseases, SNP Research Center, RIKEN, Kanagawa, Japan
Hum Mol Genet 14:3149-59. 2005..Our results suggested that in individuals with the -111T/T genotype, reduced IL-12Rbeta1 expression may lead to increased Th2 cytokine production in the skin and contribute to the development of AD and other subsequent allergic diseases...
[A comparative study between real time monitor KH-3000 and conventional Durham sampler measuring airborne pollen]Shigetoshi Yoda
Department of Otorhinolaryngology, Red Cross Society Wakayama Medical Center, Wakayama
Nippon Jibiinkoka Gakkai Kaiho 108:801-5. 2005..This report points out the need to take these conditions (snow and other plants pollen) into account when a real time monitor is used for collecting pollen information...
Functional haplotypes of IL-12B are associated with childhood atopic asthmaTomomitsu Hirota
Laboratory for Genetics of Allergic Diseases, Single Nucleotide Polymorphism Research Center, Institute of Physical and Chemical Research RIKEN, Kanagawa, Japan
J Allergy Clin Immunol 116:789-95. 2005..Although associations between polymorphisms of IL-12B on chromosome 5q31-33 and asthma have been reported, the genetic influences of the polymorphisms and haplotype of IL-12B are unclear...
[Impact of allergic rhinitis on work productivity: a pilot study]Chieko Kakutani
School of Allied Health Sciences, Faculty of Medicine, Osaka University
Arerugi 54:627-35. 2005..CONCLUSION: This study shows that we should pay more attention to ocular symptoms as well as nasal symptoms and improve patients' quality of life as soon as possible in order to reduce productivity losses...
Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthmaTomomitsu Hirota
Laboratory for Genetics of Allergic Diseases, SNP Research Center, The Institute of Physical and Chemical Research RIKEN, Kanagawa 230 0045, Japan
J Hum Genet 49:370-5. 2004..These results indicated that specific variants of the DAP3 gene might be associated with the mechanisms responsible for adult BA and contribute to airway inflammation and remodeling...
Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese populationLei Cheng
Department of Otorhinolaryngology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Int Arch Allergy Immunol 139:25-30. 2006..Recent studies revealed that a common variant in the coding region of the IL13 gene, Arg110Gln, has been implicated in the development of asthma and atopy...
