Research Topics
| M Saito-YabeSummaryAffiliation: Daiichi Sankyo Co Country: Japan Publications
|
Detail Information
Publications
Highly frequent anti-idiotype antibody in cynomolgus monkeys developed against mouse-derived regions of anti-Fas antibody humanized by complementarity determining region graftingM Saito-Yabe
Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co, Ltd, Shinagawa ku, Tokyo, Japan
Br J Pharmacol 158:548-57. 2009..We investigated the immunogenicity of a humanized anti-human Fas monoclonal antibody, R-125224, in cynomolgus monkeys to estimate its efficacy, as well as its toxicity in clinical situations...
PEGylation of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) results in decreased uptake into rats and human liverMotoko Saito-Yabe
Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co, Ltd, Tokyo, Japan
J Pharm Pharmacol 62:985-94. 2010..Our aim was to investigate the effect of PEGylation on the uptake of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) into rat liver, kidney and spleen, and human liver...
