Hiroshi Karasawa

Summary

Affiliation: Daiichi Sankyo Co

Country: Japan

A novel model of type 2 diabetes mellitus based on obesity induced by high-fat diet in BDF1 mice
Hiroshi Karasawa
Biological Research Laboratories II, Daiichi Sankyo Co, Ltd, Tokyo 140 8710, Japan
Metabolism 58:296-303. 2009
Obesity-induced diabetes in mouse strains treated with gold thioglucose: a novel animal model for studying ?-cell dysfunction
Hiroshi Karasawa
Biological Research Laboratories II, Daiichi Sankyo Co, Ltd, Tokyo, Japan
Obesity (Silver Spring) 19:514-21. 2011
Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets
Mitsuru Shimamura
Research and Development Planning Division, Daiichi Sankyo Co, Ltd, 1 2 58 Hiromachi, Shinagawa ku, Tokyo 140 8710, Japan
Biochem Biophys Res Commun 401:79-84. 2010

A novel model of type 2 diabetes mellitus based on obesity induced by high-fat diet in BDF1 mice
Hiroshi Karasawa
Biological Research Laboratories II, Daiichi Sankyo Co, Ltd, Tokyo 140 8710, Japan
Metabolism 58:296-303. 2009
..This model would be useful for exploring the mechanism of obesity-dependent type 2 diabetes mellitus and evaluating antiobesity and antidiabetic drugs...
Obesity-induced diabetes in mouse strains treated with gold thioglucose: a novel animal model for studying ?-cell dysfunction
Hiroshi Karasawa
Biological Research Laboratories II, Daiichi Sankyo Co, Ltd, Tokyo, Japan
Obesity (Silver Spring) 19:514-21. 2011
..Furthermore, comparing the genetic backgrounds of mice with different susceptibilities to diabetes may lead to the identification of novel genetic factors influencing the ability of pancreatic ?-cells to secrete insulin...
Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets
Mitsuru Shimamura
Research and Development Planning Division, Daiichi Sankyo Co, Ltd, 1 2 58 Hiromachi, Shinagawa ku, Tokyo 140 8710, Japan
Biochem Biophys Res Commun 401:79-84. 2010
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