Blocking of enhanced sensitivity to behavioral effects of naloxone induced by narcotic agonists in ratsRaka Jain
Department of Psychiatry, National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi 110 029
Indian J Physiol Pharmacol 47:407-14. 2003
..Further agonist-induced sensitization to behavioral effects of opioid antagonist appears to be opioid receptor specific...
- Neurobiology of cannabis addiction
Raka Jain
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029
Indian J Physiol Pharmacol 52:217-32. 2008
..These findings have helped in the better understanding of the issue and have provided substrate for the clinical application...
- The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review
Raka Jain
National Drug Dependence Treatment Centre and Department of Psychiatry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Pin 110029, India
Yonsei Med J 49:175-88. 2008
..Modulation of glutamatergic neurotransmission with NMDA receptor antagonists may prove to be useful in alleviating the symptoms of nicotine abstinence and facilitate tobacco-smoking cessation...
- Effects of nitric oxide synthase inhibitors in attenuating nicotine withdrawal in rats
Raka Jain
National Drug Dependence Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Pin 110029, India
Pharmacol Biochem Behav 88:473-80. 2008
..This study demonstrates that NO plays an important role in the expression of behavioral signs of nicotine withdrawal syndrome and suggests a potential use of NOS inhibitors as an aid in tobacco smoking cessation...
- Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists
Raka Jain
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, New Delhi 110029, India
Brain Res Bull 65:415-21. 2005
..Thus, caffeine produces differential cross tolerance to the amphetamine-like discriminative effects of dopaminergic drugs, a phenomenon in which the dopamine D(1) receptor appears to have an important role...
- Influence of sweet tasting solutions on opioid withdrawal
Raka Jain
Centre for Behavioural Sciences, National Drug Dependence Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Brain Res Bull 64:319-22. 2004
..These findings provide support that ingestion of high concentrations of sucrose solutions for shorter duration may activate the endogenous opioid system and appears to have an important role in modifying morphine withdrawals...
- Self-reported drug use and urinalysis results
Raka Jain
National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029
Indian J Physiol Pharmacol 48:101-5. 2004
..Clinicians should be cautious while prescribing agonist drug due to frequent over-reporting of drug use by patients in our setting. This will make the substance abuse program more meaningful...
- Assessment of differential doses of buprenorphine for long term pharmacotherapy among opiate dependent subjects
Shantanu De
National Drug Dependence Treatment Centre and Department of Psychiatry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Pin 110029, India
Indian J Physiol Pharmacol 52:53-63. 2008
..Both 2 mg/day and 4 mg/day dose of buprenorphine were effective in long term pharmacotherapy of opioid dependence without significant difference as compared by different measures used in the study...
- Urinalysis-based comparative evaluation of pattern of use of dextropropoxyphene and buprenorphine among opioid-dependent subjects
Yatan Pal Singh Balhara
Department of Psychiatry and De addiction, Lady Hardinge Medical College and SSK Hospital, New Delhi, India
J Opioid Manag 8:45-9. 2012
..This study aims at urinalysis-based comparative evaluation of pattern of use of dextropropoxyphene and buprenorphine among opioid-dependent subjects...
- Perceived health risks, attitude and readiness to quit tobacco among euthymic bipolar disorder patients in regular contact with mental health services: an exploratory study from India
Raman Deep Pattanayak
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India
J Ment Health 21:83-90. 2012
..Patients with bipolar disorder (BD) are at higher risk of tobacco-related harm compared with general population. However, they may not fully appreciate health risks even when asymptomatic...
- Comparison of self-reported benzodiazepine use and urinalysis among consecutive treatment seekers at a tertiary care drug dependence treatment centre
Raman Deep Pattanayak
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, New Delhi 110 029
Indian J Physiol Pharmacol 54:337-43. 2010
..Self report of benzodiazepine use is highly questionable among treatment seekers. The urinalysis with cassette test is a quick objective method which is recommended for routine screening...
- Impact of alcohol and substance abuse on adolescent brain: a preclinical perspective
Raka Jain
National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
Indian J Physiol Pharmacol 54:213-34. 2010
..Damage during early stages can cause long term damage which is irreversible. The present review discusses the neurobehavioral, neurochemical and neuroendocrinal effects of alcohol and other drugs of abuse on the adolescent brain in rats...
- Concordance between urinary cotinine levels and self-reported tobacco use among drug-dependent persons: a pilot study
Raka Jain
a National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi 110029, India
Subst Abus 33:99-102. 2012
..Tobacco is highly prevalent among the drug abusers. The effectiveness of the treatment program may be increased by using the combination of urine analysis along with self-report...
- A urinalysis-based study of buprenorphine and non-prescription opioid use among patients on buprenorphine maintenance
Yatan Pal Singh Balhara
Department of Psychiatry and De addiction, Lady Hardinge Medical College and SSK Hospital, New Delhi, India
J Pharmacol Pharmacother 3:15-9. 2012
..To understand the pattern of use of opioid-substitution therapy (OST) and opioid abuse among patients on buprenorphine maintenance using urinalysis...
- A comparative study of reliability of self report of tobacco use among patients with bipolar and somatoform disorders
Yatan Pal Singh Balhara
Department of Psychiatry and De addiction, Lady Hardinge Medical College and Smt Sucheta Kriplani Hospital, New Delhi, India
J Pharmacol Pharmacother 2:174-8. 2011
..To compare the use and reliability of self-reported tobacco use (both smoked and smokeless) among patients with bipolar disorder and somatoform disorders...
- Effect of buprenorphine on psychomotor functions in patients on buprenorphine maintenance
Ankush Singhal
Mental Health Unit, Lister Hospital, Stevenage, Hertfordshire, United Kingdom
J Opioid Manag 4:41-7. 2008
..This study was conducted to assess the effects of its additional doses on psychomotor performance in patients who are maintained on it...
