Research Topics
Species | F ZulianSummaryAffiliation: University of Padova Country: Italy Publications
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Publications
Localized scleroderma in childhood is not just a skin diseaseFrancesco Zulian
Dipartimento di Pediatria, Universita di Padova, Padua, Italy
Arthritis Rheum 52:2873-81. 2005..We studied the prevalence and clinical features of extracutaneous manifestations in a large cohort of children with juvenile localized scleroderma...
Systemic sclerosis and localized scleroderma in childhoodFrancesco Zulian
Department of Pediatrics, Pediatric Rheumatology Unit, University of Padova, Via Giustiniani 3, 35128 Padova, Italy
Rheum Dis Clin North Am 34:239-55; ix. 2008..They range from small plaques of fibrosis involving only the skin to diseases causing significant functional deformity with various extracutaneous features...
Outcome measures and medical progress: why outcome measures are needed in childhood arthritisFrancesco Zulian
Pediatric Rheumatology Unit, Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128 Padova, Italy
Curr Rheumatol Rep 5:463-70. 2003....
Systemic manifestations in localized sclerodermaFrancesco Zulian
Pediatric Rheumatology Unit, Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128 Padua, Italy
Curr Rheumatol Rep 6:417-24. 2004..In this paper, the various systemic manifestations reported in localized scleroderma, their incidence, their relationship with systemic sclerosis, and their relationship with other autoimmune or connective tissue diseases will be analyzed...
Severe clinical course of systemic lupus erythematosus in the first year of lifeF Zulian
Rheumatology Unit, Department of Pediatrics, University of Padua, Italy
Lupus 17:780-6. 2008..SLE can start as early as during the first year of life and is more severe than in the later age groups...
Scleroderma in childrenFrancesco Zulian
Pediatric Rheumatology Unit, Department of Pediatrics, University of Padova, Via Giustiniani 3 35128, Padua, Italy
Pediatr Clin North Am 52:521-45, vii. 2005..The close collaboration among pediatricians, rheumatologists, and dermatologists represents an important advance in the management of these disabling conditions...
Congenital localized sclerodermaFrancesco Zulian
Department of Pediatrics, University of Padua, Italy
J Pediatr 149:248-51. 2006..Juvenile localized scleroderma (JLS) usually has its onset during later childhood. This report describes the clinical and serologic features of six children with congenital localized scleroderma (CLS)...
Juvenile localized scleroderma: clinical and epidemiological features in 750 children. An international studyF Zulian
Dipartimento di Pediatria, Universita di Padova, Via Giustiniani 3, 35128 Padova, Italy
Rheumatology (Oxford) 45:614-20. 2006..With the long-term goal of developing uniform classification criteria, we studied the epidemiological, clinical and immunological features of children with JLS followed by paediatric rheumatology and dermatology centres...
Childhood systemic sclerosisFrancesco Zulian
Pediatric Rheumatology Unit, Department of Pediatrics, University of Padova, Italy
Curr Opin Rheumatol 19:592-7. 2007..Juvenile systemic sclerosis has a variety of clinical manifestations, sometimes different from the adult form. Early recognition, proper classification and treatment may improve the long-term outcome...
A new computerized method for the assessment of skin lesions in localized sclerodermaF Zulian
Department of Pediatrics, University of Padua, Italy
Rheumatology (Oxford) 46:856-60. 2007..The aim of this study is to evaluate the performance of a new computerized skin score (CSS) method for the measurement of circumscribed lesions in LS...
Successful use of extracorporeal membrane oxygenation for severe interstitial lung disease in a child with dermatomyositisFrancesco Zulian
Department of Pediatrics, University of Padua, Rheumatology Unit, Via Giustiniani 3, 35128 Padua, Italy
Intensive Care Med 33:1663-6. 2007
Triamcinolone acetonide and hexacetonide intra-articular treatment of symmetrical joints in juvenile idiopathic arthritis: a double-blind trialF Zulian
Rheumatology Unit, Department of Paediatrics, University Hospital of Padua, Via Giustiniani 3, 35128 Padova, Italy
Rheumatology (Oxford) 43:1288-91. 2004..In this study we compared the efficacy of intra-articular TA at a dose twice that of TH in symmetrically involved joints, in children with juvenile idiopathic arthritis (JIA)...
The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism provisional classification criteria for juvenile systemic sclerosisFrancesco Zulian
Dipartimento di Pediatria, University of Padua, Padua, Italy
Arthritis Rheum 57:203-12. 2007..To develop criteria for the classification of systemic sclerosis (SSc) in children (juvenile SSc)...
Methotrexate treatment in juvenile localized scleroderma: a randomized, double-blind, placebo-controlled trialFrancesco Zulian
University of Padua, Padua, Italy
Arthritis Rheum 63:1998-2006. 2011..This study was undertaken to assess the safety and efficacy of methotrexate (MTX) in the treatment of juvenile localized scleroderma...
Abatacept for severe anti-tumor necrosis factor alpha refractory juvenile idiopathic arthritis-related uveitisFrancesco Zulian
University of Padua, Padua, Italy
Arthritis Care Res (Hoboken) 62:821-5. 2010..To evaluate the safety and efficacy of abatacept in patients with severe juvenile idiopathic arthritis (JIA)-related uveitis refractory or intolerant to immunosuppressive and anti-tumor necrosis factor alpha (anti-TNFalpha) agents...
Early predictors of severe course of uveitis in oligoarticular juvenile idiopathic arthritisFrancesco Zulian
Department of Pediatrics, University of Padua, Padua, Italy
J Rheumatol 29:2446-53. 2002..To determine whether demographic, clinical, and laboratory variables at onset of arthritis can predict the development and the severity of anterior uveitis (AU) in oligoarticular juvenile idiopathic arthritis (JIA)...
Comparison of intra-articular triamcinolone hexacetonide and triamcinolone acetonide in oligoarticular juvenile idiopathic arthritisF Zulian
Department of Paediatrics, University of Padua, Italy
Rheumatology (Oxford) 42:1254-9. 2003..To compare the efficacy and safety of intra-articular triamcinolone hexacetonide (TH) and triamcinolone acetonide (TA) in children with oligoarticular juvenile idiopathic arthritis (JIA)...
Acute surgical abdomen as presenting manifestation of Kawasaki diseaseFrancesco Zulian
Department of Pediatrics, University of Padua, Padua, Italy
J Pediatr 142:731-5. 2003..Acute surgical abdomen can be the presenting manifestation of KD. In older children with fever, rash, and acute abdominal pain or hematemesis, KD should be considered in the differential diagnosis...
Safety and efficacy of iloprost for the treatment of ischaemic digits in paediatric connective tissue diseasesF Zulian
Pediatric Rheumatology Unit, University of Padua, Italy
Rheumatology (Oxford) 43:229-33. 2004..We analysed our experience with the use of iloprost for the treatment of critical ischaemic digits (ID) in children with connective tissue diseases (CTD) in order to assess its safety and efficacy...
Outcome of primary antiphospholipid syndrome in childhoodM Gattorno
Dipartimento di Pediatria, Universita di Genova, Pediatria II, Istituto G Gaslini, Italy
Lupus 12:449-53. 2003..In conclusion; our analysis suggests that some children who present with the features of primary APS may progress to develop SLE or lupus-like syndrome...
Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitisG Simonini
Department of Paediatrics, Rheumatology Unit, Anna Meyer Children s Hospital and University of Florence, Italy
Rheumatology (Oxford) 47:1510-4. 2008..To describe efficacy and safety of infliximab in the treatment of childhood chronic uveitis during a long-term follow-up...
Kawasaki's disease in northern Italy: a multicenter retrospective study of 250 patientsF Falcini
Department of Paediatrics, University of Florence, Italy
Clin Exp Rheumatol 20:421-6. 2002....
Isolated temporomandibular synovitis as unique presentation of juvenile idiopathic arthritisG Martini
Department of Pediatrics, University of Padua, Italy
J Rheumatol 28:1689-92. 2001..She underwent arthroscopic synovectomy followed by intraarticular steroid injection. Early use of synovectomy and intraarticular steroids in TMJ arthritis may reduce pain, improve jaw function, and prevent irreversible deformities...
Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classesF R Pluchinotta
Dipartimento di Pediatria, Universita di Padova, Via Giustiniani 3, 35128 Padova, Italy
Lupus 16:550-5. 2007..Postpubertal patients have a strong female preponderance and more specific signs of disease at onset. Prepubertal patients have an intermediate disease severity and no gender predilection...
Esophageal involvement in juvenile localized scleroderma: a pilot studyG Guariso
Department of Pediatrics, 1Department of Surgical and Gastroenterological ScienceUniversity of Padua, Italy
Clin Exp Rheumatol 25:786-9. 2007..To evaluate the esophageal involvement in patients with juvenile localized scleroderma (JLS)...
The Italian version of the PedsQL in children with rheumatic diseasesM Trapanotto
Department of Pediatrics, University of Padova, Italy
Clin Exp Rheumatol 27:373-80. 2009..The aim of the study was to test the reliability and validity of the Italian translation of the PedsQL 4.0 Generic Core Scales and the PedsQL 3.0 Rheumatologic Module in a sample of rheumatologic children in Italy...
Bcl-2, p53 and c-myc expression in juvenile dermatomyositisF Falcini
Department of Paediatrics, University of Florence, Italy
Clin Exp Rheumatol 18:643-6. 2000..To investigate p53, bcl-2 and c-myc expression in muscle biopsies from children affected with juvenile dermatomyositis (JDM) and to verify a possible dysregulation of programmed cell death in this autoimmune disease...
Localized and systemic forms of scleroderma in adults and children F Atzeni
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Clin Exp Rheumatol 24:S36-45. 2006..The actual and select advantage of the early nailfold videocapillaroscopic (NVC) analysis is to distinguish between the primary RP and the secondary RP and to allow the early detection of SSc...
Juvenile-onset localized scleroderma activity detection by infrared thermographyG Martini
Paediatric Rheumatology Unit, Department of Paediatrics, University of Padova, Italy
Rheumatology (Oxford) 41:1178-82. 2002..Further evaluation is needed to determine whether thermography can predict the future progression of lesions...
Severe epilepsy preceding by four months the onset of scleroderma en coup de sabreS Sartori
Department of Pediatrics, University Hospital of Padova, Padova, Italy
Clin Exp Rheumatol 27:64-7. 2009..This case report raises important questions on the pathogenesis of JLS and, particularly, on the issue whether it is a mere autoimmune condition or a neuro-cutaneous disease...
Factors affecting survival in juvenile systemic sclerosisG Martini
Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128 Padua, Italy
Rheumatology (Oxford) 48:119-22. 2009..To determine whether demographic, clinical and immunological features may predict the outcome in juvenile SSc (JSSc)...
Successful treatment of severe or methotrexate-resistant juvenile localized scleroderma with mycophenolate mofetilGiorgia Martini
Pediatric Rheumatology Unit, University of Padova, Via Giustiniani 2, Padova 35128, Italy
Rheumatology (Oxford) 48:1410-3. 2009..To evaluate the efficacy of mycophenolate mofetil (MMF) in the treatment of severe refractory juvenile localized scleroderma (JLS)...
CXCR6-CXCL16 interaction in the pathogenesis of Juvenile Idiopathic ArthritisGiorgia Martini
Pediatric Rheumatology Unit, University of Padova, Italy
Clin Immunol 129:268-76. 2008..Taken together, these data suggest that CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of JIA-associated inflammatory processes...
CXCR3/CXCL10 expression in the synovium of children with juvenile idiopathic arthritisGeorgia Martini
Department of Paediatrics, Padua University School of Medicine, Italy
Arthritis Res Ther 7:R241-9. 2005..Taken together, these data suggest that CXCR3/CXCL10 interactions are involved in the pathophysiology of JIA-associated inflammatory processes, regulating both the activation of T cells and their recruitment into the inflamed synovium...
Juvenile idiopathic arthritis: current and future treatment optionsGiorgia Martini
Department of Pediatric Rheumatology, University of Padua, Italy
Expert Opin Pharmacother 7:387-99. 2006..This review discusses the current practice in the medical management of juvenile idiopathic arthritis, and potential new agents are discussed...
Ocular involvement in children with localised scleroderma: a multi-centre studyMaria Elisabetta Zannin
Department of Pediatrics, Via Giustiniani 3, 35128 Padova, Italy
Br J Ophthalmol 91:1311-4. 2007..This article reports the frequency and specific features of ocular involvement in a large cohort of children with juvenile LS (JLS)...
A child with dermatomyositis and a suspicious lymphadenopathyGiorgia Martini
Department of Pediatrics, Pathology Institute, University of Padua, Padua, Italy
J Rheumatol 32:744-6. 2005..Accurate clinical assessment including appropriate biopsies is needed before starting glucocorticoid therapy...
Rice bodies imaging in juvenile idiopathic arthritisGiorgia Martini
Rheumatology Unit, Department of Pediatrics, University of Padua, Padua, Italy
J Rheumatol 30:2720-1. 2003
Complementary and Alternative Medicine (CAM) in paediatric rheumatology: a European perspectiveG Fadanelli
Department of Paediatric Rheumatology Unit, University of Padua, Italy
Clin Exp Rheumatol 30:132-6. 2012..To analyse the use of complementary and alternative medicine (CAM) in children with rheumatic diseases, treated at a paediatric rheumatology centre in Italy...
Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritisT Avcin
Department of Paediatrics, University of Ljubljana, Slovenia, Italy
Ann Rheum Dis 61:608-11. 2002..CONCLUSIONS: Anti-CCP can be detected in children with JIA, but are less frequently present than in adults with RA...
Otolaryngological manifestations of rheumatic diseases in childrenFrancesco Zulian
Department of Pediatrics, University of Padova, Padova, Italy
Int J Pediatr Otorhinolaryngol 73:S56-60. 2009..In this section, we will review the main characteristics of these conditions with the attempt to propose a few elements for an easy differential diagnosis which might help for an early diagnosis and a more appropriate treatment...
Systemic sclerosis in childhood: clinical and immunologic features of 153 patients in an international databaseGiorgia Martini
University of Padua, Padua, Italy
Arthritis Rheum 54:3971-8. 2006..Juvenile SSc appears to be less severe than in adults because children have less internal organ involvement, a less specific autoantibody profile, and a better long-term outcome...
New developments in localized sclerodermaFrancesco Zulian
Division of Paediatric Rheumatology, Department of Paediatrics, University of Padova, Padova, Italy
Curr Opin Rheumatol 20:601-7. 2008..Localized scleroderma, also known as morphea, is the most frequent form of scleroderma in childhood. Early diagnosis, appropriate assessment and effective treatment may improve the long-term outcome...
Arthritis and gum bleeding in two childrenAgata Vitale
Department of Paediatrics, Rheumatology Unit, University of Messina, Messina, Italy
J Paediatr Child Health 45:158-60. 2009....
Do Kawasaki disease patients without coronary artery abnormalities need a long-term follow-up? A myocardial single-photon emission computed tomography pilot studyGiulia Zanon
Rheumatology Unit, Department of Paediatrics, University of Padua, 35128 Padua, Italy
J Paediatr Child Health 45:419-24. 2009..To determine the frequency and risk factors for long-term myocardial perfusion scintigraphy abnormalities in patients with Kawasaki disease (KD)...
Is there a role for arthroscopic synovectomy in oligoarticular juvenile idiopathic arthritis?Maria M Martinez Toledo
Department of Pediatrics, University of Padua, Padua, Italy
J Rheumatol 33:1868-72. 2006..Best results are achieved early in the disease course in children with persistent monoarticular involvement and no evidence of systemic inflammation...
The Pediatric Rheumatology International Trials Organization criteria for the evaluation of response to therapy in juvenile systemic lupus erythematosus: prospective validation of the disease activity core setNicolino Ruperto
Pediatric Rheumatology International Trials Organization PRINTO, IRCCS G Gaslini, Universita di Genova, Pediatria II Reumatologia, Largo Gaslini, Genoa, Italy
Arthritis Rheum 52:2854-64. 2005..To validate and promulgate a core set of outcome measures for the evaluation of response to treatment in patients with juvenile systemic lupus erythematosus (SLE)...
A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexateNicolino Ruperto
IRCCS G Gaslini, University of Genoa, Genoa, Italy
Arthritis Rheum 50:2191-201. 2004..5 mg/m(2)/week)...
IL1 and TNF gene polymorphisms in patients with juvenile idiopathic arthritis treated with TNF inhibitorsRolando Cimaz
Unité Mixte Hospices Civils de Lyon BioMérieux, Lyon, France
Ann Rheum Dis 66:900-4. 2007....
A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritisNicolino Ruperto
IRCCS, Istituto G Gaslini, Genoa, Italy
Arthritis Rheum 56:3096-106. 2007..To evaluate the safety and efficacy of infliximab in the treatment of juvenile rheumatoid arthritis (JRA)...
Changes in markers of bone turnover and inflammatory variables during alendronate therapy in pediatric patients with rheumatic diseasesRolando Cimaz
Clinica Pediatrica, ICP, Milano, Italy
J Rheumatol 29:1786-92. 2002..In this study, we evaluated the changes in bone metabolism and disease activity markers in 45 patients ages 5 to 18 years (31 female, 14 male) with rheumatic diseases treated with alendronate for 12 months...
Painful hand and foot swelling in a 6-month-old girlElena Vanin
Paediatric Department, Arzignano Hospital, Italy
Eur J Pediatr 162:47-8. 2003
Laser Doppler flowmetry for assessing localized scleroderma in childrenLisa Weibel
Great Ormond Street Hospital for Children, London, UK
Arthritis Rheum 56:3489-95. 2007..The aim of this study was to evaluate the role of laser Doppler flowmetry (LDF) in comparison with infrared thermography in the detection of scleroderma disease activity...
Localized sclerodermaRonald M Laxer
Department of Paediatrics and Medicine, University of Toronto, Vice President, Education and Quality, The Hospital for Sick Children, Toronto, Canada
Curr Opin Rheumatol 18:606-13. 2006..Localized scleroderma, also known as morphoea, has a variety of clinical manifestations that can include systemic involvement. Early recognition, diagnosis and treatment may improve the long-term outcome...
A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis: short- and long-term efficacy and safety resultsNicolino Ruperto
IRCCS G Gaslini, Pediatria II, Reumatologia, Genoa, Italy
Arthritis Rheum 52:563-72. 2005....
