Research Topics
| G ZaninottoSummaryAffiliation: University of Padova Country: Italy Publications
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Detail Information
Publications
CDX2 hox gene product in a rat model of esophageal cancerGiuseppe Ingravallo
Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padova, Italy
J Exp Clin Cancer Res 28:108. 2009..Experimental models of longstanding esophageal reflux of duodenal-gastric contents may provide important information on the biological sequence of the Barrett's oncogenesis...- Randomized controlled trial of botulinum toxin versus laparoscopic heller myotomy for esophageal achalasiaGiovanni Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica 4, University of Padova, Padova, Italy
Ann Surg 239:364-70. 2004..To compare laparoscopic cardia myotomy and fundoplication with botulinum toxin (BoTx) injection in patients with esophageal achalasia... - The role of botulinum toxin injection and upper esophageal sphincter myotomy in treating oropharyngeal dysphagiaGiovanni Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica 3, University of Padova School of Medicine, Padova, Italy
J Gastrointest Surg 8:997-1006. 2004..If BoTox fails, CP myotomy can be offered to patients with preserved oral and tongue activity at VFS and an intact bolus propulsion ability on manometry... - Objective follow-up after laparoscopic repair of large type III hiatal hernia. Assessment of safety and durabilityGiovanni Zaninotto
Department of Gastroenterological and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padova, Italy
World J Surg 31:2177-83. 2007..The use of mesh may reduce the incidence of postoperative hernia recurrence or wrap migration in the chest... - Surgical options and outcomes in Barrett's esophagusGiovanni Zaninotto
Department of General Surgery, S Giovanni e Paolo Hospital, Venice, and Department of General Surgery and Organ Transplantation, University of Padova, Italy
Curr Opin Gastroenterol 23:452-5. 2007.... - Botulinum toxin injection versus laparoscopic myotomy for the treatment of esophageal achalasia: economic analysis of a randomized trialG Zaninotto
Department of Medical and Surgical Sciences Clinica Chirurgica 4, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padova, Italy
Surg Endosc 18:691-5. 2004..The aim of this study was to compare the clinical and economic results of two such treatments: laparoscopic myotomy and botulinum toxin injection... - Long-term outcome and risk of oesophageal cancer after surgery for achalasiaG Zaninotto
Department of General Surgery, S Giovanni e Paolo Hospital, Venice, Padua, Italy
Br J Surg 95:1488-94. 2008..The aim of the present study was to assess long-term subjective outcomes after cardiomyotomy and partial fundoplication, focusing specifically on the risk of oesophageal cancer... - Four hundred laparoscopic myotomies for esophageal achalasia: a single centre experienceGiovanni Zaninotto
Department of General Surgery, S Giovanni e Paolo Hospital, Venice, Italy
Ann Surg 248:986-93. 2008..Laparoscopic myotomy is the currently preferred treatment for achalasia. Our objectives were to assess the long-term outcome of this operation and preoperative factors influencing said outcome... - [Barrett's esophagus. Prevalence, risk of adenocarcinoma, role of endoscopic surveillance]G Zaninotto
Clinica Chirurgica 4, Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Padova, Padova, Italy
Minerva Chir 57:819-36. 2002.... - Tailored approach to Zenker's diverticulaG Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica 4, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padova, Italy
Surg Endosc 17:129-33. 2003..Zenker's diverticula (ZD) can be treated by diverticulostomy or open surgery (upper esophageal sphincter myotomy and diverticulectomy or diverticulopexy). The aim of this study was to compare the outcome of the two alternative treatments... - Long-term outcome of operated and unoperated epiphrenic diverticulaGiovanni Zaninotto
General Surgery, Venice Hospital, ULSS12, University of Padova School of Medicine, Via Giustiniani 2, 35128, Padova, Italy
J Gastrointest Surg 12:1485-90. 2008..The aim of this study was to evaluate the long-term fate of operated and unoperated patients with ED... - Minimally invasive surgery for esophageal achalasiaG Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica IV, University of Padua, School of Medicine, Italy
J Laparoendosc Adv Surg Tech A 11:351-9. 2001..The characteristic dysphagia may be alleviated by surgery, dilations, or botulinum toxin injections. Video-endoscopic surgery is used increasingly... - Etiology, diagnosis, and treatment of failures after laparoscopic Heller myotomy for achalasiaGiovanni Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica IV, University of Padova School of Medicine, Padova, Italy
Ann Surg 235:186-92. 2002..To assess the causes of failure of laparoscopic Heller myotomy and to verify whether endoscopic pneumatic dilation is a feasible treatment... - Diaphragmatic herniation after esophagectomyGiovanni Zaninotto
Istituto Oncologico Veneto (IOV, Clinica Chirurgica III, University of Padova School of Medicine, Padova, Italy
Eur J Cardiothorac Surg 30:669. 2006 - Therapeutic strategies for epiphrenic diverticula: systematic reviewGiovanni Zaninotto
Unità Operativa Complessa General Surgery, Santi Giovanni e Paolo Hospital, ULSS 12, Castello 6777, 30100, Venice, Italy
World J Surg 35:1447-53. 2011..Whatever treatment and approach are used for the patient with epiphrenic diverticula, a tailored protocol always involves detailed study of the esophageal morphology and function... - Long-term follow-up of Barrett's epithelium: medical versus antireflux surgical therapyGiovanni Zaninotto
Department of General Surgery, SS Giovanni e Paolo Hospital, ULSS 12, Venice, Italy
J Gastrointest Surg 16:7-14; discussion 14-5. 2012..Barrett's esophagus (BE) is the most serious complication of GERD. In BE patients, this observational study compares the effects of antireflux surgery versus antisecretory medical therapy... - Long-term results (6-10 years) of laparoscopic fundoplicationGiovanni Zaninotto
Department of Medical and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Via Giustiniani 2, 35128, Padova, Italy
J Gastrointest Surg 11:1138-45. 2007..Conclusion confirms that laparoscopic fundoplication provides effective, long-term treatment of gastroesophageal reflux disease. Hernia recurrence and dysphagia are its weak points... - Minimally invasive enucleation of esophageal leiomyomaG Zaninotto
Department of Medical and Surgical Sciences Clinica Chirurgica 3, University of Padova, School of Medicine, Via Giustiniani 2, 35128 Padova, Italy
Surg Endosc 20:1904-8. 2006..Thoracoscopic and laparoscopic techniques for the removal of esophageal leiomyomas may be recommended as the treatment of choice in centers experienced with minimally invasive surgery... - The laparoscopic Heller-Dor operation remains an effective treatment for esophageal achalasia at a minimum 6-year follow-upM Costantini
Department of Medical and Surgical Sciences, Clinical Chirurgica III, School of Medicine, University of Padua, Via Giustiniani, 35128, Padua, Italy
Surg Endosc 19:345-51. 2005..The aim of this study was to investigate the long-term clinical outcome of the laparoscopic Heller Dor procedure for esophageal achalasia... - Role of acid and bile reflux in development of specialised intestinal metaplasia in distal oesophagusG Zaninotto
Department of Medical and Surgical Sciences, University of Padova, Italy
Dig Liver Dis 34:251-7. 2002..Barrett's oesophagus is defined as specialised intestinal metaplasia in the distal oesophagus, regardless of extension... - Prevalence of intestinal metaplasia in the distal oesophagus, oesophagogastric junction and gastric cardia in symptomatic patients in north-east Italy: a prospective, descriptive survey. The Italian Ulcer Study Group "GISU"G Zaninotto
Dipartimento di Scienze Mediche e Chirurgiche, Universita di Padova, Facolta di Medicina, Italy
Dig Liver Dis 33:316-21. 2001..Incidence of adenocarcinoma of distal oesophagus and gastric cardia, probably arising from areas of intestinal metaplasia, has been increasing rapidly... - Pseudoachalasia: not only esophago-gastric cancerG Portale
Istituto Oncologico Veneto IOV IRCCS, University of Padova, School of Medicine, Padova, Italy
Dis Esophagus 20:168-72. 2007..The causes were a pancreatic carcinoma, a breast cancer and an histiocytosis X. Aspects of these three patients' diagnostic and therapeutic course are discussed in detail... - MAGE, BAGE, and GAGE gene expression in patients with esophageal squamous cell carcinoma and adenocarcinoma of the gastric cardiaA Zambon
Department of Oncology and Surgical Sciences, Oncology Section, University of Padova, Italy
Cancer 91:1882-8. 2001..Nevertheless, BAGE or GAGE expression was related significantly to a poor prognosis, whereas the expression of MAGE genes (in the absence of BAGE and GAGE expression) was related significantly to a good prognosis... - Surgical complications do not affect longterm survival after esophagectomy for carcinoma of the thoracic esophagus and cardiaErmanno Ancona
Instituto Oncologico Veneto, University of Padova, Padova, Italy
J Am Coll Surg 203:661-9. 2006..CONCLUSIONS: Surgical complications have no negative impact on survival rates, which seem to depend exclusively on the pathologic stage of the tumor... - Altered esophageal pain threshold in irritable bowel syndromeM Costantini
Department of Surgery Chirurgia Generale 2, University of Padua, Italy
Dig Dis Sci 38:206-12. 1993..Esophageal involvement in IBS consists of a lower pain threshold on esophageal distension, possibly reflecting an altered visceral receptor sensitivity or modulation throughout the gut... - The Veneto Region's Barrett's Oesophagus Registry: aims, methods, preliminary resultsG Zaninotto
Department of General Surgery and Organ Transplantation, University of Padova, Padova, Italy
Dig Liver Dis 39:18-25. 2007..A Barrett's Oeosphagus Registry has been therefore established in the Veneto Region and neighbouring provinces... - Only pathologic complete response to neoadjuvant chemotherapy improves significantly the long term survival of patients with resectable esophageal squamous cell carcinoma: final report of a randomized, controlled trial of preoperative chemotherapy versus E Ancona
Clinica Chirurgica 4, University of Padova School of Medicine-Azienda Ospedaliera di Padova, Padova, Italy
Cancer 91:2165-74. 2001..Major efforts should be undertaken to identify patients before neoadjuvant treatments who are likely to respond... - Pericentriolar material analyses in normal esophageal mucosa, Barrett's metaplasia and adenocarcinomaDaniela Segat
Proliferation Unit, Department of Biology, University of Padova, Italy
Histol Histopathol 25:551-60. 2010..Extending our observations in a prospective study might help in the development of new prevention protocols for adenocarcinoma patients... - Treatment of esophageal achalasia with laparoscopic Heller myotomy and Dor partial anterior fundoplication: prospective evaluation of 100 consecutive patientsG Zaninotto
Department of Medical and Surgical Sciences Clinica Chirurgica IV, University of Padua School of Medicine, Italy
J Gastrointest Surg 4:282-9. 2000..It was concluded that laparoscopic Heller myotomy with Dor fundoplication is a feasible and effective treatment for achalasia, with an actuarial success rate of 90% at 5 years... - Interval between neoadjuvant chemoradiotherapy and surgery for squamous cell carcinoma of the thoracic esophagus: does delayed surgery have an impact on outcome?Alberto Ruol
Department of Surgical and Gastrointestinal Sciences, Clinica Chirurgica I, University of Padova, Padova, Italy
Ann Surg 252:788-96. 2010..Aim of this study was to evaluate whether delayed surgery after neoadjuvant chemoradiotherapy (CRT) affects postoperative outcomes in patients with locally advanced squamous cell carcinoma (SCC) of the thoracic esophagus... - Aurora kinase A in Barrett's carcinogenesisMassimo Rugge
Department of Medical Diagnostic Sciences and Special Therapies, Pathology Unit, University of Padova, Padua, Italy
Hum Pathol 41:1380-6. 2010..The identification of AURKA as a novel molecular target of cancer progression in Barrett's mucosa provides a lead for the development of new therapeutic approaches in Barrett's mucosa patients... - Programmed cell death 4 protein in esophageal cancerMatteo Fassan
Department of Medical Diagnostic Sciences and Special Therapies, University of Padova, Padova PD, I 35100, Italy
Oncol Rep 24:135-9. 2010.... - Successful treatment of long-standing post-stroke dysphagia with botulinum toxin and rehabilitationStefano Masiero
Department of Rehabilitation Medicine, University of Padova, School of Medicine, Italy
J Rehabil Med 38:201-3. 2006..Our findings strongly suggest that even long-standing dysphagia can improve dramatically in selected patients. To the best of our knowledge, there are no other reports with such a long follow-up... - Trends in management and prognosis for esophageal cancer surgery: twenty-five years of experience at a single institutionAlberto Ruol
Department of Gastrointestinal and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padova, Italy
Arch Surg 144:247-54; discussion 254. 2009..To investigate trends in results of esophagectomies to treat esophageal cancer at a single high-volume institution during the past 25 years... - Barrett's esophagus: management of high-grade dysplasia and cancerAlberto Ruol
Clinica Chirurgica 3 degrees, University of Padova, Padova, Italy
J Surg Res 117:44-51. 2004..Finally, intensive endoscopic biopsy surveillance of patients with HGD is another investigational option that may allow prompt treatment of cancer if it develops. However, few data document the safety of this observational approach... - Helicobacter pylori, inflammation, oxidative damage and gastric cancer: a morphological, biological and molecular pathwayFabio Farinati
Departments of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy
Eur J Cancer Prev 17:195-200. 2008..The growing body of evidence of the regression of precancerous changes and the high prevalence of superficial gastric carcinoma demonstrated in long-term follow-up studies on NiN make this approach mandatory... - Laparoscopic live donor nephrectomy: single center experienceN Baldan
Dipartimento di Chirurgia Generale e Trapianti d Organo, U O Trapianti Rene e Pancreas, Azienda Ospedaliera, Universita di Padova, Padova, Italy
Transplant Proc 39:1787-90. 2007..The aim of this study was a retrospective assessment of the safety of laparoscopic live donor nephrectomy (LLDN) and the outcome of these renal transplantations... - Oesophageal diverticulaMario Costantini
Clinica Chirugica IV, Department of Medical and Surgical Sciences, University of Padua, 2, Via Giustiniani, Padua, Italy
Best Pract Res Clin Gastroenterol 18:3-17. 2004..On the other hand, laparoscopic treatment of epiphrenic diverticula has recently been introduced with encouraging results. However, because the disease is rare, more experience is required in order to allow definitive conclusions... - Barrett's epithelium after antireflux surgeryGiovanni Zaninotto
Department of General Surgery, University of Padova School of Medicine, Italy
J Gastrointest Surg 9:1253-60; discussion 1260-1. 2005..A drop in the immunohistochemical expression of Cdx2 protein was also only documented in the SBE group. Antireflux surgery significantly modifies the histologic phenotype of SBE, but not of LBE... - Survivin in esophageal cancer: An accurate prognostic marker for squamous cell carcinoma but not adenocarcinomaAntonio Rosato
Department of Oncology and Surgical Sciences, University of Padova, Padova, Italy
Int J Cancer 119:1717-22. 2006..0147). In esophageal adenocarcinoma, survivin expression and pattern of distribution had no prognostic relevance. Thus, quantifying survivin expression provides a prognostic marker only for esophageal squamous tumors... - Programmed cell death 4 nuclear loss and miR-21 or activated Akt overexpression in esophageal squamous cell carcinogenesisM Fassan
Department of Medical Diagnostic Sciences and Special Therapies, Surgical Pathology and Cytopathology Unit Department of Oncological and Surgical Sciences, General Oncology Unit Department of Gastroenterological and Surgical Sciences, Surgery Unit, University of Padova Endoscopy Unit Surgical Pathology Unit, Istituto Oncologico del Veneto IOV IRCCS, Padova, Italy
Dis Esophagus 25:263-8. 2012..PDCD4 down-regulation, as assessed by immunohistochemistry, is a reliable biomarker of early-stage squamous cell esophageal neoplasia, providing additional information in the histological assessment of these lesions... - Results of esophagectomy for esophageal cancer in elderly patients: age has little influence on outcome and survivalAlberto Ruol
Department of Medical and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Padova, Italy
J Thorac Cardiovasc Surg 133:1186-92. 2007..The aim of this study was to assess the effects of age on the outcome of surgery for esophageal cancer at a single institution... - Zenker's diverticula: feasibility of a tailored approach based on diverticulum sizeChristian Rizzetto
Istituto Oncologico Veneto IOV IRCCS, Padua, Italy
J Gastrointest Surg 12:2057-64; discussion 2064-5. 2008..The aim of this study was to compare the effectiveness of a minimally invasive (group A) versus a traditional open surgical approach (group B) in the treatment of ZD... - DNA copy number alterations correlate with survival of esophageal adenocarcinoma patientsGiulia Pasello
Oncology Section, Department of Oncology and Surgical Sciences, University of Padova, Padova, Italy
Mod Pathol 22:58-65. 2009..In addition, the finding of alterations specific for the more aggressive esophageal adenocarcinoma subset might represent promising biomarkers to increase the accuracy of clinical outcome prediction... - Long-term outcome of laparoscopic Heller-Dor surgery for esophageal achalasia: possible detrimental role of previous endoscopic treatmentGiuseppe Portale
Department of Medical and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Padova, Italy
J Gastrointest Surg 9:1332-9. 2005..Heller-Dor surgery is safe and effective as a primary or a second-line treatment (after pneumatic dilations or BT injections) for achalasia. However, long-term results seem less satisfactory in patients previously treated with BT... - Esophageal achalasia: is the herpes simplex virus really innocent?Ignazio Castagliuolo
Department of Histology, Medical and Surgical Sciences-Clinica Chirurgica 4, University of Padova School of Medicine, Padova, Italy
J Gastrointest Surg 8:24-30; discussion 30. 2004..We hypothesize that the HSV-1-reactive lymphocytes in lower esophageal sphincter muscles of achalasia patients may contribute to damage of the neurons in the myenteric plexus and lead to the motor dysfunction... - Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesisAnna Parenti
Section of Pathologic Anatomy, Department of Oncological and Surgical Sciences, University of Padova, 35100, Italy
Hum Pathol 37:16-22. 2006..Expression of caspase 3 in BE and dysplasia may be ascribed to accumulation of the nonactivated form, as the antibody used detects both cleaved and uncleaved caspase 3... - Esophageal GIST: case report of surgical enucleation and update on current diagnostic and therapeutic optionsGiuseppe Portale
Istituto Oncologico Veneto IOV IRCCS, Clinica Chirurgica III, University of Padova School of Medicine, Via Giustiniani 2, 35128 Padua, Italy
Int J Surg Pathol 15:393-6. 2007..The authors present the case of an esophageal GIST and discuss the diagnostic course and therapeutic options, as currently reported in the literature... - [Diaphragmatic herniation after oesophagectomy: a report of two cases]Sabrina Rampado
Dipartimento di Scienze Mediche e Chirurgiche, Clinica Chirurgica III, Universita degli Studi di Padova
Chir Ital 59:411-6. 2007..Surgical repair is the treatment of choice and is mandatory as emergency treatment in the case of symptomatic hernias... - Image of the month. Cystic mesotheliomaGiuseppe Portale
Department of Medical and Surgical Sciences, Clinica Chirurgica III, University of Padova School of Medicine, Padova, Italy
Arch Surg 142:401-2. 2007 - T cells in the myenteric plexus of achalasia patients show a skewed TCR repertoire and react to HSV-1 antigensMonica Facco
Department of Clinical and Experimental Medicine, Hematology and Clinical Immunology Branch, Padua University School of Medicine, Padova, Italy
Am J Gastroenterol 103:1598-609. 2008.... - Erosion of an esophageal endoprosthesis into the tracheaSabrina Rampado
Department of Medical and Surgical Sciences, Clinica Chirurgica III, University of Padova Medical School, Padova, Italy
Ann Thorac Surg 82:2278-80. 2006..Surgical technique and final outcome depends on fistula size. A one-stage procedure with esophageal resection is preferred when the fistula is located in the upper third of the trachea and is less than 1 cm long... - Regression of low-grade noninvasive neoplasia in barrett's epithelium: should we lower our guard?Giovanni Zaninotto
Ann Surg 245:337-8. 2007 - Barrett's Registries in Europe: report of an International WorkshopChristine P J Caygill
UK National Barrett s Oesophagus Registry, Royal Free Hospital, London, UK
Eur J Cancer Prev 17:426-9. 2008..It was concluded that there were enough areas of similarity and common objectives for EBRA to be set up for future collaboration... - Mediastinal carcinosis involving the esophagus in breast cancer: the "breast-esophagus" syndrome: report on 25 cases and guidelines for diagnosis and treatmentSabrina Rampado
Istituto Oncologico Veneto IOV IRCCS, Italy
Ann Surg 246:316-22. 2007..Breast metastases of mucosal/submucosal layers of the esophagus are extremely rare: esophageal involvement is usually part of a mediastinal carcinosis... - Re: CDX2 homeotic gene expression in gastric noninvasive neoplasiaMassimo Rugge
Am J Surg Pathol 28:834-5; author reply 835. 2004