Research Topics
| Alessandra RussoSummaryAffiliation: University of Catania Country: Italy Publications
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Detail Information
Publications
Improved antioxidant effect of idebenone-loaded polyethyl-2-cyanoacrylate nanocapsules tested on human fibroblastsMaddalena Palumbo
Institute of Biochemistry, University of Catania, Italy
Pharm Res 19:71-8. 2002..CONCLUSIONS: The findings reported here demonstrate that an improved antioxidant effect was obtained with a low idebenone concentration (0.5 microM) when the drug was entrapped within Tween 80-coated PECA nanocapsules...
Bacopa monniera, a reputed nootropic plant: an overviewA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
Phytomedicine 12:305-17. 2005..Moreover, other clinical studies have to be encouraged, also to evidence any side effects and possible interactions between this herbal medicine and synthetic drugs...
Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 proteinA Russo
Department of Drug Sciences, Section of Biochemistry, University of Catania, Catania, Italy
Chem Biol Interact 195:1-10. 2012..The combination of vicanicin (4) and protolichesterinic acid (5) with other anti-prostate cancer therapies could be considered a promising strategy that warrants further in vivo evaluation...
Boldo prevents UV light and nitric oxide-mediated plasmid DNA damage and reduces the expression of Hsp70 protein in melanoma cancer cellsAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
J Pharm Pharmacol 63:1219-29. 2011..In addition, we investigated the growth inhibitory activity of this natural product against human melanoma cells (M14)...
Nitric oxide-related toxicity in cultured astrocytes: effect of Bacopa monnieraAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Life Sci 73:1517-26. 2003..This data supports the traditional use of BM and indicates that this medicinal plant has a therapeutic potential in treatment or prevention of neurological diseases...
Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damageAlessandra Russo
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125, Catania, Italy
Phytother Res 17:870-5. 2003..Moreover, this experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role...
Chilean propolis: antioxidant activity and antiproliferative action in human tumor cell linesA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania Italy
Life Sci 76:545-58. 2004..Results showed that this Chilean propolis sample exhibits interesting biological properties, correlated with its chemical composition and expressed by its capacity to scavenge free radicals and to inhibit tumor cell growth...
Antioxidant activity and antiproliferative action of methanolic extract of Geum quellyon Sweet roots in human tumor cell linesAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, 95125 Catania, Italy
J Ethnopharmacol 100:323-32. 2005..The effect evidenced in Caco-2 cells can be in part correlated to a modulation of redox-sensitive mechanisms...
Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cellsAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, 95125 Catania, Italy
J Nutr Biochem 17:103-8. 2006..These results suggest that also genistin, due to its antioxidant and anticarcinogenic properties, contributes to the overall biological activity of soy and could have promising applications in the field of dermatology...
Propolis protects human spermatozoa from DNA damage caused by benzo[a]pyrene and exogenous reactive oxygen speciesA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Life Sci 78:1401-6. 2006....
Pannarin inhibits cell growth and induces cell death in human prostate carcinoma DU-145 cellsAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125, Catania, Italy
Anticancer Drugs 17:1163-9. 2006..The experimental evidence is further confirmed by caspase-3 activity results, evidencing a reduction in the activity of this protease at a higher concentration, 50 micromol/l...
Putrescine-1,4-dicinnamide from Pholiota spumosa (Basidiomycetes) inhibits cell growth of human prostate cancer cellsA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Phytomedicine 14:185-91. 2007....
Lichen metabolites prevent UV light and nitric oxide-mediated plasmid DNA damage and induce apoptosis in human melanoma cellsA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
Life Sci 83:468-74. 2008....
Rosmarinus officinalis extract inhibits human melanoma cell growthAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Nat Prod Commun 4:1707-10. 2009..No statistically significant increase in LDH release was observed in melanoma cells, correlated to a fragmentation of genomic DNA, determined by COMET assay...
Effect of litreol on the viability of human cancer cellsAlessandra Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Chem Biol Interact 179:178-84. 2009....
Ethanol-induced oxidative stress in rat astrocytes: role of HSP70A Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, Faculty of Pharmacy, University of Catania, Italy
Cell Biol Toxicol 17:153-68. 2001....
Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-beta-d-glucosideAlessandra Russo
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania 95100, Italy
J Nutr Biochem 16:31-7. 2005..C3G (0.125, 0.250 mM) added to the cells treated with 50 microM OTA significantly reduced free radical species production and prevented genomic DNA damage...
Resveratrol and propolis as necrosis or apoptosis inducers in human prostate carcinoma cellsChristian Scifo
Department of Biological Chemistry, Medicinal Chemistry and Molecular Biology, University of Catania, Viale Andrea Doria, 6, 95125 Catania, Italy
Oncol Res 14:415-26. 2004..The data obtained suggest the possible use of these micronutrients both in alternative to classic chemotherapy, and in combination with very low dosage of vinorelbine (5 microM)...
Essential oils of Salvia bracteata and Salvia rubifolia from Lebanon: Chemical composition, antimicrobial activity and inhibitory effect on human melanoma cellsVenera Cardile
Department of Physiological Sciences, University of Catania, 95125 Catania, Italy
J Ethnopharmacol 126:265-72. 2009..The oils were also tested for their potential antiproliferative effects against M14 human melanoma cells...
Involvement of HSP70 in resveratrol-induced apoptosis of human prostate cancerVenera Cardile
Department of Physiological Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy
Anticancer Res 23:4921-6. 2003..CONCLUSION: Our results confirm the ability of resveratrol to suppress the proliferation of human prostate cancer cells with a typical apoptotic feature, interfering with the expression of HSPs70...
Red wine micronutrients as protective agents in Alzheimer-like induced insultA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V.le A. Doria 6, 95125, Catania, Italy
Life Sci 72:2369-79. 2003..The experimental results suggest that this natural compound may be used to ameliorate the progression of pathology in AD disease therapy...
Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidantsR Acquaviva
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
Cell Biol Toxicol 19:243-52. 2003..These effects suggest that anthocyanins exhibit interesting antioxidant properties, and could therefore represent a promising class of compounds useful in the treatment of pathologies where free radical production plays a key role...
DNA topoisomerase i as a transcription protein and a lethal cellular toxinLuca Lotito
Department of Biochemistry, University of Bologna, Bologna, Italy
Ital J Biochem 56:122-9. 2007..Moreover, we will discuss recent findings on the targeting of topoisomerase I to pre-selected sites in transcribed chromatin by fusion to a sequence-specific DNA-binding protein domain...
Effect of propolis on human cartilage and chondrocytesVenera Cardile
Department of Physiological Sciences, University of Catania, V.le A. Doria 6, 95125, Catania, Italy
Life Sci 73:1027-35. 2003..Our data clearly demonstrated the protective action of propolis in cartilage alteration, that appears greater than that elicited by indomethacin, commonly employed in joint diseases...
Indian medicinal plants as antiradicals and DNA cleavage protectorsA Russo
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Italy
Phytomedicine 8:125-32. 2001....
Placing the newborn on the maternal abdomen increases the volume of umbilical cord blood collectedC Pafumi
Department of Microbiological and Gynaecological Sciences, University of Catania, Italy
Clin Lab Haematol 23:397-9. 2001..The simple manoeuvre of placing the newborn on the maternal abdomen after delivery may thus increase the yield of transplantable haematopoietic progenitor cells in cord blood...
Pregnancy outcome of a transfusion-dependent thalassemic womanC Pafumi
University Department of Obstetrics and Gynaecology, S Bambino Hospital, Catania, Italy
Ann Hematol 79:571-3. 2000..Therefore, women now affected by Cooley disease may possibly have a normal pregnancy without ovulation induction, intrauterine growth retardation, foetal loss and preterm labour...
L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protectorA Vanella
Institute of Biochemistry, University of Catania, Italy
Cell Biol Toxicol 16:99-104. 2000..In fact, it was able to scavenge superoxide anion, to inhibit the lipoperoxidation of linoleic acid, and to protect pBR322 DNA from cleavage induced by H2O2 UV-photolysis...
Adenomyosis and uterus rupture during laborC Pafumi
Institute of Obstetrics and Gynaecology, University of Catania, Via G D Annunzio no 125, 95127 Catania, Italy
Zhonghua Yi Xue Za Zhi (Taipei) 64:244-6. 2001..Our experience suggests that a silent and spontaneous uterine rupture, is possible even in the absence of the principal risk factors...
ET-18-OCH(3)-induced cytotoxicity and DNA damage in rat astrocytesM Renis
Institute of Biochemistry, Faculty of Pharmacy, University of Catania, Viale Andrea Doria, 6, 95125, Catania, Italy
Int J Dev Neurosci 18:545-55. 2000....
Two enrichment methods to obtain CD34+ stem cells from umbilical cord bloodC Pafumi
Microbiological and Gynaecological Science Department, University of Catania, Via G D Annunzio no 125, 95127 Catania, Italy
Bratisl Lek Listy 102:183-6. 2001....
Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galanginA Russo
Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125, Catania, Italy
Fitoterapia 73:S21-9. 2002..CAPE, used alone, exhibited a strong antioxidant activity, higher than galangin. The experimental evidence, therefore, suggests that CAPE plays an important role in the antioxidant activity of propolis...
Influence of the kind of delivery on umbilical cord blood collectionC Pafumi
Department of Microbiological and Gynaecological Sciences, University of Catania, Italy
Haematologia (Budap) 31:341-5. 2002..The higher median volume of blood collected from infants delivered by Caesarean section seems mainly due to the different clamping time, rather than to the kind of delivery...
Two CD34+ stem cells from umbilical cord blood enrichment methodsC Pafumi
Institute of Obstetrics and Gynaecology, University of Catania, Italy
Pediatr Hematol Oncol 19:239-45. 2002....
Comparison of dexa and ultrasonometry in the measurement of bone densityC Pafumi
Department of Microbiological and Gynaecological Sciences, University of Catania, Italy
Arch Gynecol Obstet 266:152-3. 2002..Mean height cm 164+/-2.8; mean weight kg 68+/-3.2. The most concordant results were obtained in group B. This suggests that QUS screening for osteoporosis may be suitable for the "younger" perimenopausal patient...
Glutamine synthetase activity and HSP70 levels in cultured rat astrocytes: effect of 1-octadecyl-2-methyl-rac-glycero-3-phosphocholineM Renis
Institute of Biochemistry, Faculty of Pharmacy, University of Catania, Catania, Italy
Brain Res 783:143-50. 1998..Its analog compound platelet-activating factor (PAF) shares some of these biological aspects...
Is endoscopic ultrasound clinically useful for follow-up of gastric lymphoma?F Di Raimondo
Divisione Clinicizzata di Ematologia, Universita di Catania, Ospedale Ferrarotto, Catania, Italy
Ann Oncol 18:351-6. 2007....
Differences in umbilical cord blood units collected during cesarean section, before or after the delivery of the placentaC Pafumi
Department of Microbiological and Gynecological Sciences, Section of Endocrinology, Andrology and Internal Medicine, University of Catania, Italy
Gynecol Obstet Invest 54:73-7. 2002..7 +/- 6.0 versus 60.9 +/- 13.7 ml; the cord blood nucleated cell number was 10.1 +/- 1.2 x 10(8) vs. 7.1 +/- 0.8 x 10(8); and the mean cord blood CD34+ cell number was 20.0 +/- 6.0 x 10(5) vs. 16.4 +/- 2.4 x 10(5), respectively...
VLA-2 and VLA-5 cell adhesion molecules expression in CD34+ cells from umbilical cord blood and from bone marrowC Pafumi
Department of Microbiological and Gynaecological Sciences, University of Catania, Italy
Blood Purif 20:174-6. 2002..The aim of this study is to investigate the number of two cell adhesion molecules in cord blood and in bone marrow...
DNA damage in human fibroblasts exposed to fumonisin B(1)F Galvano
Department of Agro Forestry, Environmental Science and Technology, University of Reggio Calabria, P zza S Francesco 7, Reggio Calabria, Italy
Food Chem Toxicol 40:25-31. 2002....
Early clamping of umbilical cord blood and foetal CD34 enrichmentC Pafumi
Department of Microbiology, University of Catania, Italy
Acta Med Austriaca 28:141-4. 2001..This increases the possibility of reducing graft versus host disease in adult patients and produces survival rates similar to the ones we observed in transplantation of bone marrow from unrelated donors...
Pro-apoptotic activity of ergosterol peroxide and (22E)-ergosta-7,22-dien-5alpha-hydroxy-3,6-dione in human prostate cancer cellsA Russo
Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V le A Doria 6, 95125 Catania, Italy
Chem Biol Interact 184:352-8. 2010....
Umbilical cord blood collection in Cesarean section: a comparison before and after placental deliveryC Pafumi
Department of Microbiology and Obstetrical Science, Via G D Annunzio, 125 95127, Catania, Italy
Arch Gynecol Obstet 266:193-4. 2002..The mean volume of fetal blood collected while the placental was still in utero was 74.93+/-7.1 ml as against 35.78+/-3.6 ml for collection of fetal blood after delivery of the placenta...
Branching projections of catecholaminergic ventrolateral reticular neurons to the fastigial nucleus and superior colliculus in the rat: triple labelling procedureS Stanzani
Department of Physiological Sciences; University of Catania, Viale A. Doria, 6-95125, Catania, Italy
Neurosci Lett 307:135-8. 2001..The projections were defined by injections of two retrograde tracers: rhodamine and fluoro gold in the SC and FN, respectively...
Magnetic resonance cholangiopancreatography and contrast-enhanced magnetic resonance cholangiopancreatography versus endoscopic ultrasonography in the diagnosis of extrahepatic biliary pathologyS Palmucci
Sezione di Scienze Radiologiche Dipartimento Dogira, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele, Via Santa Sofia 78, Catania, Italy
Radiol Med 115:732-46. 2010..This study compared the diagnostic accuracy of magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasonography (EUS) in evaluating the cause of extrahepatic bile duct dilatation...
The role of the phenethyl ester of caffeic acid (CAPE) in the inhibition of rat lung cyclooxygenase activity by propolisAntonietta Rossi
Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy
Fitoterapia 73:S30-7. 2002..001) difference. These results suggest that both CAPE and galangin contribute to the overall activity of propolis, CAPE being more effective...
Antiproliferative activity of Pteleopsis suberosa leaf extract and its flavonoid components in human prostate carcinoma cellsMarinella De Leo
Dipartimento di Chimica Bioorganica e Biofarmacia, , Pisa, Italy
Planta Med 72:604-10. 2006....
Intracellular distribution of beta-catenin in human medulloblastoma cell lines with different degree of neuronal differentiationRoberta Salaroli
Clinical Department of Radiological and Histopathological Sciences, Bologna, Italy
Ultrastruct Pathol 31:33-44. 2007..These observations support an important functional role of WNT/beta-catenin pathway in neuronal differentiation in medulloblastoma...
