Research Topics
| F PiscagliaSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
Contrast-enhanced Ultrasound for Liver Imaging: Recent AdvancesVeronica Salvatore
Division of Internal Medicine, Dept of Digestive Disease and Internal Medicine, Azienda Ospedaliero universitaria S Orsola Malpighi, Via Albertoni, 15, 40138 Bologna, Italy
Curr Pharm Des 18:2236-52. 2012....
Accuracy of VirtualTouch Acoustic Radiation Force Impulse (ARFI) imaging for the diagnosis of cirrhosis during liver ultrasonographyF Piscaglia
Div Internal Medicine, Dept Clinical Medicine, University and General Hospital S Orsola Malpighi, Bologna
Ultraschall Med 32:167-75. 2011..The goal of the present study was to analyze the diagnostic accuracy of VirtualTouch in the diagnosis of cirrhosis and its correlation with transient elastography (Fibroscan)...
Malignancies in primary biliary cirrhosisFabio Piscaglia
Department of Internal Medicine and Gastroenterology, Division of Internal Medicine, Bolondi, Bologna, Italy
Eur J Gastroenterol Hepatol 20:1-4. 2008..Such surveillance should start only when PBC patients have reached disease stage IV (frank cirrhosis)...
Criteria for diagnosing benign portal vein thrombosis in the assessment of patients with cirrhosis and hepatocellular carcinoma for liver transplantationFabio Piscaglia
Division of Internal Medicine, Department of Digestive Disease and Internal Medicine, St Orsola Malpighi University Hospital, Bologna, Italy
Liver Transpl 16:658-67. 2010..In conclusion, for a patient with HCC and portal vein thrombosis, appropriate investigations can establish whether the thrombosis is benign; patients with HCC and benign portal vein thrombosis are candidates for liver transplantation...
Diagnostic features of real-time contrast-enhanced ultrasound in focal nodular hyperplasia of the liverF Piscaglia
Department of Clinical Medicine, Division of Internal Medicine, University of Bologna
Ultraschall Med 31:276-82. 2010..The aim of the present study was to assess the ultrasound pattern of FNH with special attention to real-time contrast-enhanced ultrasonography (CEUS) appearance and specifically to the timing of perfusion patterns...
Cost analysis of recall strategies for non-invasive diagnosis of small hepatocellular carcinomaFabio Piscaglia
Division of Internal Medicine, Department of Digestive Diseases and Internal Medicine, University of Bologna, Bologna, Italy
Dig Liver Dis 42:729-34. 2010..Which is the least expensive recall policy for nodules in the cirrhotic liver remains unclear...
Real time contrast enhanced ultrasonography in detection of liver metastases from gastrointestinal cancerFabio Piscaglia
Division Internal Medicine, Azienda Ospedaliero Universitaria S, Orsola Malpighi, Bologna, Italy
BMC Cancer 7:171. 2007....
Prediction of significant fibrosis in hepatitis C virus infected liver transplant recipients by artificial neural network analysis of clinical factorsFabio Piscaglia
Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
Eur J Gastroenterol Hepatol 18:1255-61. 2006....
Characterization of focal liver lesions with contrast-enhanced ultrasoundFabio Piscaglia
Division of Internal Medicine, Department of Clinical Medicine, University of Bologna, Bologna, Italy
Ultrasound Med Biol 36:531-50. 2010....
A new priority policy for patients with hepatocellular carcinoma awaiting liver transplantation within the model for end-stage liver disease systemFabio Piscaglia
Department of Internal Medicine and Gastroenterology, Sant Orsola Malpighi Hospital, Bologna, Italy
Liver Transpl 13:857-66. 2007..This model allows the timely transplantation of patients with HCC without severely affecting the outcome of patients without HCC...
Value of splanchnic Doppler ultrasound in the diagnosis of portal hypertensionF Piscaglia
Division of Internal Medicine, University of Bologna, Via Albertoni, Bologna, Italy
Ultrasound Med Biol 27:893-9. 2001..60 and 12 cm/s(-1), which appeared to be, therefore, the most favorable parameters for the clinical practice. Their use may limit the need for endoscopy to search for varices...
Acute systemic, splanchnic and renal haemodynamic changes induced by molecular adsorbent recirculating system (MARS) treatment in patients with end-stage cirrhosisG Donati
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Aliment Pharmacol Ther 26:717-26. 2007..To evaluate the acute effect of treatment with the molecular adsorbent recirculating system (MARS) on splanchnic, renal and systemic haemodynamics in patients with end-stage cirrhosis...
Mars and Prometheus: our clinical experience in acute chronic liver failureS Faenza
Department of Surgery, Intensive Care and Transplantation, Policlinico Sant Orsola, Bologna, Italy
Transplant Proc 40:1169-71. 2008..In our clinical context, there are two groups that practice blood purification treatments on acute or chronic liver failure (AoCLF) patients: one group used MARS (molecular adsorbent recirculating system) and the other Prometheus...
Small (<or=3 cm) hepatocellular carcinoma in cirrhosis: the role of double contrast agents in MR imaging vs. multidetector-row CTR Golfieri
Radiologia Malpighi, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Universita di Bologna, Via Albertoni 15, 40138, Bologna, Italy
Radiol Med 114:1239-66. 2009..dynamic MRI plus SPIO-MRI (double-contrast MRI: DC-MRI) for the detection of small (<or=3 cm) hepatocellular carcinomas (HCCs)...
Influence of liver fibrosis on hepatic artery Doppler resistance index in chronic hepatitis of viral originF Piscaglia
Division of Internal Medicine, Dept. of Internal Medicine and Gastroenterology, University of Bologna, Azienda Ospedaliera S. Orsola-Malpighi, Bologna, Italy
Scand J Gastroenterol 36:647-52. 2001..CONCLUSIONS: The increase in hepatic artery resistance index appears to be influenced by the extent of fibrous tissue deposition in the liver, determined by chronic inflammation and repair and, secondly, by ageing...
Liver transplantation for hepatocellular carcinoma: results of down-staging in patients initially outside the Milan selection criteriaM Ravaioli
Department of Liver and Multi organ Transplantation, Pathology Division of The F Addarii Institute, Sant Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
Am J Transplant 8:2547-57. 2008..The actuarial intention-to-treat survival was 27/48 patients (56.3%) in the down-staging and 81/129 cases (62.8%) in the Milan group, p = n.s. The proposed down-staging criteria provide a comparable outcome to the conventional criteria...
Diurnal changes of fibrinolysis in patients with liver cirrhosis and esophageal varicesF Piscaglia
Department of Internal Medicine, University of Bologna, Bologna, Italy
Hepatology 31:349-57. 2000....
Role of real-time contrast-enhanced ultrasound in the assessment of metastatic portal vein thrombosisA Venturi
Department of Internal Medicine and Gastroenterology, St Orsola Malpighi University Hospital, Bologna, Italy
Ultraschall Med 28:75-8. 2007....
Management of small hepatocellular carcinomaS Leoni
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Acta Gastroenterol Belg 69:230-5. 2006..This review describes some critical points regarding the detection, diagnosis and therapeutic management of small nodules of HCC in cirrhotic patients...
Artificial neural network is superior to MELD in predicting mortality of patients with end-stage liver diseaseA Cucchetti
Dipartimento di Discipline Chirurgiche, Rianimatorie e dei Trapianti, University of Bologna, S Orsola Malpighi Hospital, 9 40138 Bologna, Italy
Gut 56:253-8. 2007....
Assessment of liver fibrosis in transplant recipients with recurrent HCV infection: usefulness of transient elastographyF Corradi
Department of Internal Medicine and Gastroenterology, Division of Internal Medicine Bolondi, Italy
Dig Liver Dis 41:217-25. 2009..Progression of recurrent hepatitis C is accelerated in liver transplant recipients, leading to special need of non-invasive validated methods to estimate liver fibrosis...
Analysis of risk factors for early hepatic artery thrombosis after liver transplantation. Possible contribution of reperfusion in the early morningF Piscaglia
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Malpighi Hospital, Via Albertoni 15, 40138 Bologna, Italy
Dig Liver Dis 39:52-9. 2007....
Tumor doubling time predicts recurrence after surgery and describes the histological pattern of hepatocellular carcinoma on cirrhosisAlessandro Cucchetti
Dipartimento di Discipline Chirurgiche, Rianimatorie e dei Trapianti, University of Bologna, Policlinico S.Orsola, Via Massarenti 9, 40138 Bologna, Italy
J Hepatol 43:310-6. 2005..007), undifferentiation (P=0.003) and high alpha-fetoprotein levels (P=0.011). CONCLUSIONS: DT is easy to estimate and indicates the prognosis of single HCCs prior to liver resection...
Review article: liver transplantation for HCC. Treatment options on the waiting listL Bolondi
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology and Division of General and Transplantation Surgery, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
Aliment Pharmacol Ther 17:145-50. 2003..However, the overall efficacy of this approach will be established only in some years...
Different haemodynamic effects of a single dose of long-acting isosorbide-5-mononitrate in healthy subjects and patients with cirrhotic portal hypertensionF Piscaglia
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Azienda S Orsola Malpighi, Via Albertoni 15, 40138 Bologna, Italy
Dig Liver Dis 36:594-602. 2004..The action pathways of nitrates are hypothesised to be deranged in cirrhosis...
New perspectives for the use of contrast-enhanced liver ultrasound in clinical practiceL Bolondi
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Via Albertoni 15, 40138 Bologna, Italy
Dig Liver Dis 39:187-95. 2007..Therefore, it is necessary to take measures in order to meet the demand for an increasing number of these procedures...
Clinical trial: peg-interferon alfa-2b and ribavirin for the treatment of genotype-1 hepatitis C recurrence after liver transplantationF Lodato
Department of Digestive Diseases and Internal Medicine, Azienda Ospedaliero Universitaria Policlinico Sant Orsola Malpighi, Bologna, Italy
Aliment Pharmacol Ther 28:450-7. 2008..Treatment of hepatitis C virus (HCV) recurrence after liver transplantation (LT) is difficult with low response rates...
Left ventricular volumes in liver cirrhosisF Piscaglia
Division of Internal Medicine, University of Bologna, Italy
Dig Liver Dis 32:392-7. 2000..Patients with alcoholic cirrhosis have left ventricular dimensions similar to controls. Few data have been reported in patients with cirrhosis of viral origin...
Preoperative prediction of hepatocellular carcinoma tumour grade and micro-vascular invasion by means of artificial neural network: a pilot studyAlessandro Cucchetti
Liver and Multiorgan Transplant Unit, Policlinico S Orsola Malpighi, University of Bologna, Italy
J Hepatol 52:880-8. 2010..The aim of this study was to develop an artificial neural network (ANN) that is able to predict tumour grade and MVI on the basis of non-invasive variables...
The impact of vascular and nonvascular findings on the noninvasive diagnosis of small hepatocellular carcinoma based on the EASL and AASLD criteriaSimona Leoni
Department of Digestive Diseases and Internal Medicine, University of Bologna, Bologna, Italy
Am J Gastroenterol 105:599-609. 2010....
Molecular adsorbent recirculating system (MARS) application in liver failure: clinical and hemodepurative results in 22 patientsS Stefoni
Nephrology, Dialysis and Renal Transplantation Unit, S Orsola University Hospital, Bologna, Italy
Int J Artif Organs 29:207-18. 2006..Acute liver failure (ALF) and acute on chronic liver failure (ACLF) still show a poor prognosis. MARS was used in 22 patients with ALF or ACLF to prolong patient survival for liver function recovery or as a bridge to transplantation...
Comparison of recurrence of hepatocellular carcinoma after resection in patients with cirrhosis to its occurrence in a surveilled cirrhotic populationAlessandro Cucchetti
Department of Surgery and Transplantation, University of Bologna, Italy
Ann Surg Oncol 16:413-22. 2009..Annual incidence of HCC 2 years or more after resection may be similar to that of general patients because the same risk factors are involved; assessment of these characteristics could be useful in tailoring clinical management...
Fitz-Hugh-Curtis-syndrome mimicking acute cholecystitis: value of new ultrasound findings in the differential diagnosisF Piscaglia
Div Internal Medicine, Dept of Internal Medicine and Gastroenterology, University of Bologna, Italy
Ultraschall Med 26:227-30. 2005..This prompted laparoscopic exploration of the subdiaphragmatic space, and the final diagnosis of Fitz-Hugh-Curtis-syndrome was made. Such ultrasound finding appears to be a new diagnostic feature of this syndrome...
Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: role of insulin resistanceG Donati
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Azienda S Orsola-Malpighi, Bologna, Italy
Gut 53:1020-3. 2004..029), and body mass index (p = 0.048). CONCLUSION: The higher prevalence of non-alcoholic fatty liver in non-obese hypertensive patients with normal liver enzymes appears to be related to increases in insulin resistance and body weight...
Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysisL Bolondi
Dipartimento di Medicina Interna e Gastroenterologia, Universita di Bologna, Italia
Gut 48:251-9. 2001..This neoplasm is associated with liver cirrhosis (LC) in more than 90% of cases. Early diagnosis and treatment of HCC are expected to improve survival of patients...
Review article: percutaneous treatment of hepatocellular carcinomaS Gaiani
Dipartimento di Medicina Interna e Gastroenterologia, Universita di Bologna, Italy
Aliment Pharmacol Ther 17:103-10. 2003..Randomized controlled trials are needed in order to assess treatment response, long-term survival, rate of complication and cost-efficacy of newer technologies in comparison to ethanol injection...
Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomographyStefano Gaiani
Dipartimento di Medicina Interna e Gastroenterologia, Alma Mater Studiorum, Universita di Bologna, Via Albertoni 15, 40138 Bologna, Italy
J Hepatol 41:421-6. 2004....
Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinomaLuigi Bolondi
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Hepatology 42:27-34. 2005..Relying on imaging techniques in nodules of 1 to 2 cm would miss the diagnosis of HCC in up to 38% of cases. Any nodule larger than 2 cm should be regarded as highly suspicious for HCC...
Analysis of risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma: key role of immunosuppressionMarco Vivarelli
Department of Surgery and Transplantation, University of Bologna, S Orsola Hospital, Bologna, Italy
Liver Transpl 11:497-503. 2005..High CsA exposure favors tumor recurrence; CsA blood levels should be kept to the effective minimum in HCC patients. In the presence of pathologic and histologic risk factors, specific immunosuppressive protocols should be considered...
Caution in the use of boldo in herbal laxatives: a case of hepatotoxicityFabio Piscaglia
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, IT 40138 Bologna, Italy
Scand J Gastroenterol 40:236-9. 2005..Transaminases promptly returned to normal after withdrawal of the laxative. It is concluded that boldo leaf extracts might be hepatotoxic, at least in elderly patients with fatty liver...
Effect of Levovist on splanchnic hemodynamics in cirrhotic patientsStefano Gaiani
Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi di Bologna, Bologna, Italy
Ultrasound Med Biol 29:643-8. 2003..It might have implications on harmonic imaging US protocols designed to image the cirrhotic liver in the early arterial phase...
Use of perfusional angiosonography in liver transplantation and conservative management of post-transplant intra-hepatic pseudo-aneurysmFabio Piscaglia
Division of Internal Medicine Bolondi, Department of Internal Medicine and Gastroenterology, Policlinico S Orsola Malpighi, Via Albertoni 15, 40138 Bologna, Italy
Transpl Int 17:634-8. 2004..The combination of the two ultrasound techniques was useful in following the course of the pseudo-aneurysm, without further need for angiography. Eventually, this pseudo-aneurysm underwent spontaneous obliteration...
Predictors of sustained virological response after antiviral treatment for hepatitis C recurrence following liver transplantationMatteo Cescon
General Surgery and Transplant Unit, Department of General Surgery and Transplantation, University of Bologna, Bologna, Italy
Liver Transpl 15:782-9. 2009..The rate of AVT discontinuation due to side effects was similar between groups (16% versus 8%, P = 0.3). In conclusion, the type of immunosuppression during AVT may predict SVR in patients treated for HCV recurrence after LT...
Effect of potassium canrenoate, an anti-aldosterone agent, on incidence of ascites and variceal progression in cirrhosisLuigi Bolondi
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Clin Gastroenterol Hepatol 4:1395-402. 2006....
Liver metastases from rectal carcinoma: disease progression during chemotherapy despite loss of arterial-phase hypervascularity on real-time contrast-enhanced harmonic sonography at low acoustic energyFabio Piscaglia
Division of Internal Medicine, University of Bologna, Azienda Ospedaliera S. Orsola-Malpighi, Via Albertoni 15, 40138 Bologna, Italy
J Clin Ultrasound 31:387-91. 2003..In this case, changes in arterial perfusion over time did not parallel the response of liver metastases to chemotherapy...
The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigationsFabio Piscaglia
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Ultrasound Med Biol 32:1369-75. 2006....
Characterization of liver lesions by real-time contrast-enhanced ultrasonographyNatascia Celli
Division of Internal Medicine, Department of Internal Medicine and Gastroenterology, Alma Mater Studiorum, University of Bologna, Italy
Eur J Gastroenterol Hepatol 19:3-14. 2007....
Long term follow-up and outcome of liver transplantation for alcoholic liver disease: a single center case-control studyMaurizio Biselli
Department of Clinical Medicine, University of Bologna, Azienda Ospedaliero Universitaria, Policlinico S Orsola Malpighi, Bologna, Italy
J Clin Gastroenterol 44:52-7. 2010..Alcoholic liver cirrhosis (ALC) is a leading indication for orthotopic liver transplantation (OLT)...
Detection of HCV antigens in liver graft: relevance to the management of recurrent post-liver transplant hepatitis CAlberto Grassi
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna Sant Orsola Malpighi Hospital, Bologna, Italy
Liver Transpl 12:1673-81. 2006..A high number of infected cells, independently from the genotype, represents a negative predictive factor of response to antiviral treatment...
Hepatic artery thrombosis and graft ischemia in the presence of preserved arterial inflow: not a contradiction but a real possibilityGiuliano La Barba
Department of Surgery and Transplantation, University of Bologna, Bologna, Italy
Liver Transpl 10:710-1. 2004
Recent advances in the imaging of hepatocellular carcinoma. From ultrasound to positron emission tomography scanValeria Camaggi
Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
Saudi Med J 28:1007-14. 2007..A typical vascular pattern in a nodule perceptible also without contrast is highly specific for HCC, so that non-invasive diagnostic algorithms have been developed and recently updated...
The intermediate hepatocellular carcinoma stage: Should treatment be expanded?Fabio Piscaglia
Division of Internal Medicine, Dept of Digestive Disease and Internal Medicine, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
Dig Liver Dis 42:S258-63. 2010..Patients not achieving complete necrosis and patients with early large recurrence should be managed individually, taking into consideration systemic treatments, which usually are reserved for advanced cases...
In human hepatocellular carcinoma in cirrhosis proliferating cell nuclear antigen (PCNA) is involved in cell proliferation and cooperates with P21 in DNA repairLaura Gramantieri
Center for Applied Biomedical Research CRBA, University of Bologna and St Orsola Malpighi University Hospital, Bologna, Italy
J Hepatol 39:997-1003. 2003..During DNA-synthesis and repair the only active PCNA fraction is tightly bound to DNA. Similarly, during DNA-repair, a fraction of p21 colocalizes with PCNA in a detergent-insoluble form...
Influence of the spleen on portal haemodynamics: a non-invasive study with Doppler ultrasound in chronic liver disease and haematological disordersF Piscaglia
Dept of Internal Medicine and Gastroenterology, University of Bologna, Italy
Scand J Gastroenterol 37:1220-7. 2002..In an attempt to elucidate these questions, we assessed splanchnic haemodynamics in chronic liver diseases and various other disorders with splenomegaly...
Assessment of donor steatosis in liver transplantation: is it possible without liver biopsy?Alessandro Cucchetti
Liver and Multiorgan Transplant Unit, University of Bologna, Sant Orsola Malpighi Hospital, Bologna, Italy
Clin Transplant 23:519-24. 2009..It would, therefore, be helpful to be able to predict the degree of steatosis, on the basis of non-invasive readily available variables...
Echo-enhanced ultrasonography: is it the future gold standard of imaging in acute pancreatitis?Emilio Brocchi
Department of Internal Medicine and Gastroenterology, Sant'Orsola-Malpighi Hospital, Alma Mater Studiorum, University of Bologna, Bologna, Italy
JOP 6:464-6. 2005..Most importantly, this technique should be also useful for following-up patients and it may be also an alternative to MRI in those patients in whom contrast-enhanced computed tomography cannot be carried out...
Cirrhosis does not shift the circadian phase of plasma fibrinolysisFabio Piscaglia
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Am J Gastroenterol 97:1512-7. 2002....
Contrast-enhanced ultrasound in the diagnosis of hepatocellular carcinomaRiccardo Lencioni
Division of Diagnostic and Interventional Radiology, Department of Oncology, Transplants, and Advanced Technologies in Medicine, Cisanello University Hospital, Via Paradisa 2, University of Pisa, Pisa, Italy
J Hepatol 48:848-57. 2008..Hence, CT or MR imaging are still mandatory for proper intrahepatic staging of the disease...
Percutaneous ablation procedures in cirrhotic patients with hepatocellular carcinoma submitted to liver transplantation: Assessment of efficacy at explant analysis and of safety for tumor recurrenceMaurizio Pompili
Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Roma, Italy
Liver Transpl 11:1117-26. 2005..RFA provides complete necrosis in most nodules smaller than 3 cm, and appears to be the best treatment option in these cases...
Selecting patients with hepatocellular carcinoma for transplantationFabio Piscaglia
Liver Transpl 13:1203; author reply 1204. 2007
Portal pressure and DopplerFabio Piscaglia
Ultrasound Med Biol 29:495-6. 2003
Onset of bronchiolitis obliterans organizing pneumonia in a liver transplant recipient under peg-interferon and ribavirin treatmentCristina Crespi
Intern Emerg Med 3:77-80. 2008
Expression of reelin in hepatic stellate cells and during hepatic tissue repair: a novel marker for the differentiation of HSC from other liver myofibroblastsDominik Kobold
Department of Internal Medicine, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
J Hepatol 36:607-13. 2002..Hepatic stellate cells (HSC) and rat liver myofibroblasts (rMF), two similar but not identical cell populations, play a major role during hepatic tissue repair...
