Guido Modiano

Summary

Affiliation: University of Rome Tor Vergata
Country: Italy

Publications

  1. ncbi Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): a reservoir of genetic variation
    Simona Fornarino
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Pavia, Italy
    BMC Evol Biol 9:154. 2009
  2. ncbi A large-scale study of the random variability of a coding sequence: a study on the CFTR gene
    Guido Modiano
    Department of Biology, University of Tor Vergata Rome, Via della Ricerca, Scientifica, 001333 Roma, Italy
    Eur J Hum Genet 13:184-92. 2005
  3. ncbi Cystic fibrosis and lactase persistence: a possible correlation
    Guido Modiano
    Department of Biology, University of Roma, Tor Vergata, Italy
    Eur J Hum Genet 15:255-9. 2007
  4. ncbi Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria
    David Modiano
    Dipartimento di Scienze di Sanità Pubblica, University of Rome La Sapienza, Rome, Italy
    Hum Mol Genet 17:789-99. 2008
  5. ncbi Anthropological features of the CFTR gene: Its variability in an African population
    Bianca Maria Ciminelli
    Department of Biology, University of Roma Tor Vergata, Italy
    Ann Hum Biol 38:203-9. 2011
  6. ncbi Haplotype block structure study of the CFTR gene. Most variants are associated with the M470 allele in several European populations
    Fiorenza Pompei
    Department of Biology, University of Roma-Tor Vergata, Italy
    Eur J Hum Genet 14:85-93. 2006

Collaborators

Detail Information

Publications6

  1. ncbi Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): a reservoir of genetic variation
    Simona Fornarino
    Dipartimento di Genetica e Microbiologia, Universita di Pavia, Pavia, Italy
    BMC Evol Biol 9:154. 2009
    ..Until now, however, investigations on their genetic structure have been scarce mainly identifying East Asian signatures...
  2. ncbi A large-scale study of the random variability of a coding sequence: a study on the CFTR gene
    Guido Modiano
    Department of Biology, University of Tor Vergata Rome, Via della Ricerca, Scientifica, 001333 Roma, Italy
    Eur J Hum Genet 13:184-92. 2005
    ..These results imply that the majority of the subpolymorphic nonsynonymous alleles of these genes are selectively negative or even pathogenic...
  3. ncbi Cystic fibrosis and lactase persistence: a possible correlation
    Guido Modiano
    Department of Biology, University of Roma, Tor Vergata, Italy
    Eur J Hum Genet 15:255-9. 2007
  4. ncbi Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria
    David Modiano
    Dipartimento di Scienze di Sanità Pubblica, University of Rome La Sapienza, Rome, Italy
    Hum Mol Genet 17:789-99. 2008
    ....
  5. ncbi Anthropological features of the CFTR gene: Its variability in an African population
    Bianca Maria Ciminelli
    Department of Biology, University of Roma Tor Vergata, Italy
    Ann Hum Biol 38:203-9. 2011
    ..It has been extensively explored in several European and European-derived populations, but poorly studied in the other major human groups...
  6. ncbi Haplotype block structure study of the CFTR gene. Most variants are associated with the M470 allele in several European populations
    Fiorenza Pompei
    Department of Biology, University of Roma-Tor Vergata, Italy
    Eur J Hum Genet 14:85-93. 2006
    ..These findings make us suggest a role for selection acting either on the M470V itself or through an hitchhiking mechanism involving a second site. The possible ancient origin of the V allele in an 'out of Africa' time frame is discussed...