Research Topics
Species | Lina MateraSummaryAffiliation: University of Turin Country: Italy Publications
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Detail Information
Publications
In vitro maturation of dendritic cells from blood progenitorsLina Matera
Laboratory of Tumor Immunology, Department of Internal Medicine, University of Turin, Italy
Methods Mol Biol 215:417-26. 2003
Effect of prolactin on the antigen presenting function of monocyte-derived dendritic cellsL Matera
Department of Internal Medicine, University of Turin, Italy
Lupus 10:728-34. 2001....
The choice of the antigen in the dendritic cell-based vaccine therapy for prostate cancerLina Matera
Laboratory of Tumor Immunology, Department of Internal Medicine, University of Turin, Turin, Italy
Cancer Treat Rev 36:131-41. 2010..In advanced stages, vaccine can still be effective when combined with systemic or local cytoreductive therapies, which may overcome antigen specific tolerance and subvert the tumor immunosuppressive environment...
Increased expression of HSP70 by colon cancer cells is not always associated with access to the dendritic cell cross-presentation pathwayLina Matera
Deptartment of Internal Medicine, University of Turin, Italy
Cell Mol Biol Lett 12:268-79. 2007..Of the three CTL-generating tumors, only one expressed hsp70. This data indicates a tumor-specific expression of hsp70, but does not support its relevance in the DC cross-presentation of TAs...
Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cellsJoanna Kopecka
Department of Genetics, Biology and Biochemistry, University of Turin, Via Santena 5 bis, Turin, Italy
J Cell Mol Med 15:1492-504. 2011..Our work suggests that the levels of nitric oxide and Pgp critically modulate the recognition of the tumour cells by dendritic cells, and proposes a new potential therapeutic approach against chemo-immunoresistant tumours...
Drug- and cell-mediated antitumor cytotoxicities modulate cross-presentation of tumor antigens by myeloid dendritic cellsAlessandra Galetto
Department of Oncology, Centro OncoEmatologicoSubalpino (COES, University of Turin, Italy
Anticancer Drugs 14:833-43. 2003..Together, these data indicate that apoptotic death induced by anti-cancer therapies can induce distinct patterns of class I MHC cross-presentation of gastric carcinoma-associated antigens to cytotoxic T lymphocyte precursors...
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cellsSara De Boo
Department of Genetics, Biology and Biochemistry, University of Turin, Via Santena 5 bis, 10126 Turin, Italy
Mol Cancer 8:108. 2009..To clarify this issue, we compared the doxorubicin-sensitive human colon cancer HT29 cells with the drug-resistant HT29-dx cells and the HT29 cells silenced for iNOS (HT29 iNOS-)...
Immunogenicity of 56 degrees C and UVC-treated prostate cancer is associated with release of HSP70 and HMGB1 from necrotic cellsDavide Brusa
Laboratory of Tumor Immunology, Department of Internal Medicine, University of Turin, Turin, Italy
Prostate 69:1343-52. 2009..Prostate hyperthermia and photodynamic therapy can be delivered by a variety of procedures which result in a wide range of temperatures and light energy and cause different kinds of cell death...
Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activityDavide Brusa
Laboratory of Tumor Immunology, Department of Internal Medicine, University of Turin, Turin, Italy
Vaccine 26:6422-32. 2008..These data offer a description of the molecular and immunogenic characteristics of post-apoptotic tumors which can be exploited to increase the efficiency of in vivo and ex vivo TAA delivery to the DC cross-presentation pathway...
Contribution of dendritic cells' FcgammaRI and FcgammaRIII to cross-presentation of tumor cells opsonized with the anti-MHC class I monoclonal antibodiesElena Signorino
Laboratory of Tumor Immunology, University of Turin, Turin, Italy
Cancer Biol Ther 6:1932-7. 2007....
Binding of prostate-specific membrane antigen to dendritic cells: a critical step in vaccine preparationStefano Garetto
Laboratory of Tumor Immunology, Department of Internal Medicine, University of Turin, Turin, Italy
Cytotherapy 11:1090-100. 2009..We evaluated the actual binding of selected HLA-A2-restricted PSMA peptides to HLA class I molecules on ex vivo-generated mature (m) DC...
Influence of drug-induced apoptotic death on processing and presentation of tumor antigens by dendritic cellsStefano Buttiglieri
Department of Oncology, Centro OncoEmatologicoSubalpino (COES, Turin, Italy
Int J Cancer 106:516-20. 2003....
Correlation between NK function and response to trastuzumab in metastatic breast cancer patientsAlessandra Beano
Dept of Medical Oncology, Molinette s Hospital, Turin, Italy, 2Laboratory of Tumour Immunology, Dept of Internal Medicine, Universityof Turin, Italy
J Transl Med 6:25. 2008..This study addresses the correlation between overall NK function and trastuzumab's clinical activity...
Prostatectomy restores the maturation competence of blood dendritic cell precursors and reverses the abnormal expansion of regulatory T lymphocytesDavide Brusa
Laboratory of Tumor Immunology, San Giovanni Battista Hospital, Turin, Italy
Prostate 71:344-52. 2011..To verify the presence of deviated dendritic cell (DC) precursors and of suppressor lymphocytes (Treg) in tumor bearing prostate cancer (PCa) patients and to monitor the corrective effect of tumor ablation...
Fluoride-containing bioactive glasses inhibit pentose phosphate oxidative pathway and glucose 6-phosphate dehydrogenase activity in human osteoblastsLoredana Bergandi
Department of Genetics, Biology and Biochemistry, University of Turin, Via Santena 5 bis, Turin, Italy
Chem Biol Interact 183:405-15. 2010....
