Research Topics
Species | G L MarsegliaSummaryAffiliation: University of Pavia Country: Italy Publications
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Publications
Rhinosinusitis and asthmaG L Marseglia
Department of Paediatrics Foundation IRCCS Policlinico San Matteo, University of Pavia, Italy
Int J Immunopathol Pharmacol 23:29-31. 2010..Thus, it becomes more and more important to perform a simple, easy and safe nasal endoscopy, in order to have a better chance to treat asthmatic children correctly by identifying a subclinical or an occult rhinosinusal infection...
The 10-day mark is a good way to diagnose not only acute rhinosinusitis but also adenoiditis, as confirmed by endoscopyGian Luigi Marseglia
Dipartimento di Scienze Pediatriche, Fondazione IRCCS Policlinico San Matteo, Universita di Pavia, P le Golgi, 2, 27100 Pavia, Italy
Int J Pediatr Otorhinolaryngol 71:581-3. 2007..This 10-day mark is considered to separate simple upper viral respiratory infection from ARS. Thus, the aim of the study was to evaluate a group of children with suspected ARS by performing nasal endoscopy...
Increased risk of otitis media with effusion in allergic children presenting with adenoiditisGian Luigi Marseglia
Dipartimento di Scienze Pediatriche, Universita di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
Otolaryngol Head Neck Surg 138:572-5. 2008..Otitis media with effusion (OME) is a common disorder in childhood. The aim of the study was to assess the association of atopy and endoscopic features with the presence of OME...
Serotonin in allergic rhinitis: a possible role for behavioural symptomsGiorgio Ciprandi
Dipartimento di Scienze Pediatriche, Direttore Scuola di Specializzazione in Pediatria, Università degli Studi di Pavia Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
Iran J Allergy Asthma Immunol 10:183-8. 2011..This preliminary study demonstrates that SAR influences serotonin concentrations and that serum serotonin could serve as a biomarker in AR patients with behavioural symptoms...
Role of forced expiratory flow at 25-75% as an early marker of small airways impairment in subjects with allergic rhinitisGian Luigi Marseglia
Department of Pediatrics, IRCCS Policlinico San Matteo, University of Pavia, Italy
Allergy Asthma Proc 28:74-8. 2007..This study provides evidence that there is a relationship between SAD and allergic parameters such as nasal symptoms and eosinophils...
Chronic urticaria caused by Hymenolepis nana in an adopted girlG L Marseglia
Dipartimento di Scienze Pediatriche - Fondazione IRCCS Policlinico San Matteo, Piazzale Golgi 2, 27100 Pavia, Italy
Allergy 62:821-2. 2007
Acute isolated sphenoid sinusitis in childrenGian Luigi Marseglia
Dipartimento di Scienze Pediatriche, IRCCS Policlinico San Matteo, Universita di Pavia, Italy
Int J Pediatr Otorhinolaryngol 70:2027-31. 2006..The aim of this report is to discuss our cases of acute isolated sphenoiditis and compare them with those reported in the International literature...
Sublingual immunotherapy in children: facts and needsGian Luigi Marseglia
Department of Paediatrics Foundations IRCCS Policlinico San Matteo, University of Pavia, Italy
Ital J Pediatr 35:31. 2009..Since then, many other studies became available and make possible to analyze SLIT in children in its well defined aspects as well as in sides still requiring more solid data...
Role of adenoids and adenoiditis in children with allergy and otitis mediaGian Luigi Marseglia
Department of Pediatric Sciences, Foundation IRCCS Policlinico San Matteo University of Pavia, P le Golgi, 2 27100, Pavia, Italy
Curr Allergy Asthma Rep 9:460-4. 2009....
Inflammation of paranasal sinuses: the clinical pattern is age-dependentG L Marseglia
Dipartimento di Scienze Pediatriche, Università di Pavia Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
Pediatr Allergy Immunol 18:10-2. 2007....
Clinical presentation of acute rhinosinusitis in children reflects paranasal sinus developmentGian Luigi Marseglia
Dipartimento di Scienze Pediatriche, Fondazione IRCCS Policlinico San Matteo, Universita di Pavia, Italy
Rhinology 45:202-4. 2007..The aim of the study was to establish whether age may have any influence on the clinical presentation during childhood...
Clinical assessment of nasal decongestion test by VAS in adolescentsGian Luigi Marseglia
Dipartimento di Scienze Pediatriche, Università di Pavia Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
Pediatr Allergy Immunol 20:187-91. 2009..In conclusion, the use of VAS appears as clinically relevant, in that it allows, with a fair reliability, to perform the decongestion test in the absence of rhinomanometry...
Passive exposure to smoke results in defective interferon-gamma production by adenoids in children with recurrent respiratory infectionsGian Luigi Marseglia
Department of Paediatric Sciences, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
J Interferon Cytokine Res 29:427-32. 2009..The effect of smoke exposure seems to be specific to the IFN-gamma-producing CD8+ cells in adenoids and may contribute to the increased susceptibility to the recurrence of respiratory infections...
Long term persistence of anti-HBs protective levels in young patients with type 1 diabetes after recombinant hepatitis B vaccineG Marseglia
Department of Pediatrics, University of Pavia, IRCCS Policlinico S Matteo, P le Golgi 2, 27100, Pavia, Italy
Vaccine 19:680-3. 2000..These data demonstrate the persistence of anti-HBs levels in children, adolescents and young patients with type 1 diabetes after recombinant hepatitis B vaccine showing evidence of longterm immunogenity and protective effect...
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiencyV Monafo
Department of Pediatric Sciences, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
Pediatr Dermatol 17:227-30. 2000....
Antibiotic treatment alone for acute rhinosinusitis gives a poor response in allergic childrenG L Marseglia
Dipartimento di Scienze Pediatriche IRCCS Policlinico San Matteo, Universita di Pavia, Italy
Int J Immunopathol Pharmacol 20:97-101. 2007..28, McNemar test p<0.001). Antibiotic therapy alone in the treatment of ARS may be generally insufficient to resolve symptoms, mainly endoscopic signs. Moreover, in allergic children this issue appears to be more evident...
Adenoids during childhood: the factsG L Marseglia
Department of Pediatrics, University of Pavia Foundation IRCCS Policlinico San Matteo, Italy
Int J Immunopathol Pharmacol 24:1-5. 2011..Several studies are still needed to better understand the relationship between allergies and infections and the influence they play on adenoids during childhood...
Specific immunotherapy in children: the evidenceM La Rosa
Department of Pediatrics, University of Catania, Italy
Int J Immunopathol Pharmacol 24:69-78. 2011..New forms of immunotherapy, allergen products and approaches to food allergy and atopic eczema represents the future of SIT...
Deficiency of INFgamma producing cells in adenoids of children exposed to passive smokeM A Avanzini
Research Laboratories, Transplantation Area, IRCCS Policlinico S Matteo, Pavia, Italy
Int J Immunopathol Pharmacol 19:609-16. 2006..This reduction may be a contributing factor in the increasing susceptibility to respiratory tract infection in children exposed to tobacco smoke...
Inhalation therapy in asthmatic and not asthmatic childrenL Lo Valvo
Department of Pediatrics, University of Catania, Italy
Int J Immunopathol Pharmacol 24:61-7. 2011..Whatever the chosen inhaler, inhaler technique is the critical factor in the correct use of delivery devices and patient education has a key-role for improving technique and compliance...
Perioperative allergy: uncommon agentsS Caimmi
Department of Pediatrics, University of Pavia, Italy
Int J Immunopathol Pharmacol 24:S61-8. 2011..Patients must be fully informed of investigation results, and advised to provide a detailed report prior to future anesthesia...
Nasal disease and asthmaG L Marseglia
Department of Pediatrics, University of Pavia Foundation IRCCS Policlinico San Matteo, Pavia, Italy
Int J Immunopathol Pharmacol 24:7-12. 2011....
Perioperative allergy: therapyG B Pajno
Department of Pediatrics, University of Messina, Messina, Italy
Int J Immunopathol Pharmacol 24:S101-4. 2011..A treatment algorithm is suggested, with emphasis on the incremental titration of adrenaline and fluid therapy as first-line treatment. Increased focus on this subject will hopefully lead to prompt diagnosis and rapid, correct treatment...
Antibiotic allergyS Caimmi
Department of Pediatrics, University of Pavia, Italy
Int J Immunopathol Pharmacol 24:S47-53. 2011....
Adenoid assessment in paediatric patients: the role of flexible nasal endoscopyF Pagella
Department of Otorhinolaryngology Foundation IRCCS Policlinico San Matteo, Pavia, Italy
Int J Immunopathol Pharmacol 24:49-54. 2011..In our opinion, nasal endoscopy in children is a reliable, safe, accurate, easily tolerated and dynamic diagnostic method to assess the adenoid size...
In vitro activation of mononuclear cells by two probiotics: Lactobacillus paracasei I 1688, Lactobacillus salivarius I 1794, and their mixture (PSMIX)A M Castellazzi
Department of Pediatric Sciences, Foundation IRCCS Policlinico San Matteo, University of Pavia, Italy
Immunol Invest 36:413-21. 2007..Most studies on probiotics have described their effects on the human immune system after ingestion of LAB, but little is known about their effect on in vitro stimulation of human immune cells...
Friday asthma crisis in the daughter of two bakersS Caimmi
Department of Pediatrics, Azienda Ospedaliera Ospedale Maggiore di Crema, Cremona, Italy
Int J Immunopathol Pharmacol 24:517-8. 2011..We confirmed our diagnosis through an inhalation food challenge. Further, by reviewing her personal history, we suspect inhalation was the mechanism in which the girl became sensitised to sesame...
TLR2 and TLR4 gene polymorphisms and atopic dermatitis in Italian children: a multicenter studyC Salpietro
Department of Pediatrics, Unit of Pediatric Genetics and Immunology, University of Messina, Italy
Int J Immunopathol Pharmacol 24:33-40. 2011..17?5.17; RR 2.24; 95 percent CI 1.15-4.45). CONCLUSION Children with AD may have a distinct genotype and the TLR-2 R753Q SNP was prevalent in a subset of patients with AD characterized by a more severe clinical picture...
Perioperative anaphylaxis: epidemiologyS Caimmi
Department of Pediatrics, University of Pavia, Italy
Int J Immunopathol Pharmacol 24:S21-6. 2011..Moreover, current epidemiological data should be carefully evaluated since the various studies published concerned non-homogeneous populations and gave differing definitions of drug hypersensitivity...
A prospective study on children with initial diagnosis of transient hypogammaglobulinemia of infancy: results from the Italian Primary Immunodeficiency NetworkV Moschese
Department of Pediatrics, Policlinico Tor Vergata, University of Rome Tor Vergata, Viale Oxford 81, Rome, Italy
Int J Immunopathol Pharmacol 21:343-52. 2008..Early recognition of children with hypogammaglobulinemia during infancy who are likely to suffer from permanent immunodeficiencies later in life would allow prompt and appropriate laboratory and clinical interventions...
Response to long-term hGH therapy in two children with Schwachman-Diamond syndrome associated with GH deficiencyG L Marseglia
Clinica Pediatrica dell Universita, IRCCS Policlinico S Matteo, Pavia, Italia
Horm Res 50:42-5. 1998..However, the presence of metaphyseal disorders probably interferes with the long-term efficacy of growth hormone substitutive therapy...
Holoprosencephaly with neurogenic hypernatremia: a new caseS Savasta
Department of Pediatrics, IRCCS Policlinico S Matteo, University of Pavia, Piazzale Golgi, 2, 27100, Pavia, Italy
Childs Nerv Syst 24:139-42. 2008....
Relationships between allergic inflammation and nasal airflow in children with seasonal allergic rhinitisGiorgio Ciprandi
Ospedale San Martino, Genoa, Italy
Ann Allergy Asthma Immunol 94:258-61. 2005..Allergic rhinitis is characterized by a T(H)2-dependent inflammation. Nasal obstruction is a typical symptom of allergic rhinitis...
Nasal obstruction is the key symptom in hay fever patientsGiorgio Ciprandi
Cirillo and Vizzaccaro Ospedale Marina Militare, Genoa, Italy
Otolaryngol Head Neck Surg 133:429-35. 2005..Allergic rhinitis is characterized by a Th2-dependent inflammation. Nasal obstruction largely depends on allergic inflammation...
Quality of life and polysensitization in young men with intermittent asthmaIgnazio Cirillo
Dipartimento di Medicina, Ospedale Marina Militare, La Spezia, Italy
Ann Allergy Asthma Immunol 94:640-3. 2005....
Nasal airflow recovery after decongestion test is associated with bronchial hyperreactivity in patients with allergic rhinitisGiorgio Ciprandi
Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
Otolaryngol Head Neck Surg 134:255-9. 2006..The decongestion test involves spraying an intranasal vasoconstrictor drug to evaluate the recovery of nasal airflow...
Role of FEF25%-75% as a predictor of bronchial hyperreactivity in allergic patientsIgnazio Cirillo
Dipartimento di Medicina, Ospedale Marina Militare, La Spezia, Italy
Ann Allergy Asthma Immunol 96:692-700. 2006..001). CONCLUSION: This study highlights the possible role of FEF25%-75% in predicting BHR in allergic individuals with airway disorders...
Role of FEF25-75 as an early marker of bronchial impairment in patients with seasonal allergic rhinitisGiorgio Ciprandi
Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
Am J Rhinol 20:641-7. 2006..The aim of this study was to evaluate whether patients with seasonal allergic rhinitis (SAR) without symptoms of asthma might, nevertheless, have airways obstruction both in and out of the pollen season...
Montelukast in allergic diseases beyond asthmaSalvatore Leonardi
Department of Pediatrics, University of Catania, Catania, Italy
Allergy Asthma Proc 28:287-91. 2007..although additional controlled testing will be required, these applications broaden the possible range of treatments for allergic disease in all its many aspects...
Nasal resistance and allergic inflammation depend on allergen typeMatteo Gelardi
Dipartimento di Oculistica e Otorinolaringoiatria, , Bari, Italy
Int Arch Allergy Immunol 141:384-9. 2006..022 and p = 0.007, respectively). Nasal resistances were higher in the pollen group (p = 0.001). CONCLUSIONS: This study provides evidence that inflammatory cell pattern and nasal resistance depend on the type of allergen sensitization...
Toll-like receptor 2-positive and Toll-like receptor 4-positive cells in adenoids of children exposed to passive smokingAntonio Ricci
J Allergy Clin Immunol 115:631-2. 2005
Sublingual immunotherapy: an update on immunologic and functional effectsGiorgio Ciprandi
University Hospital San Martino, Genoa, Italy
Allergy Asthma Proc 28:40-3. 2007..SLIT should be able to induce a specific T-reg. response. SLIT is an alternative route of administration for SIT. Recent evidence shows that SLIT is also able to induce a T-reg. response as detected by IL-10 production...
Nasal eosinophils and reversibility to the decongestion test in patients with perennial allergic rhinitisGiorgio Ciprandi
Azienda Ospedaliera Universitaria San Martino, Genoa, Italy
Allergy Asthma Proc 28:292-5. 2007..338). This study provides evidence of a significant association between nasal eosinophils and the reversibility to the decongestion test in patients with PAR...
Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot studyGiorgio Ciprandi
Allergologia U O ORL, Dipartimento Regionale Testa Collo, Padiglione Specialità piano terzo, Ospedale San Martino, Largo R Benzi 10, 16132, Genoa, Italy
Int Immunopharmacol 5:1800-8. 2005..Nasal obstruction is the main symptom in patients with perennial allergic rhinitis. Some new antihistamines have been demonstrated to be capable of improving this symptom...
Nasal decongestion test in allergic rhinitis: definition of responderGiorgio Ciprandi
Dipartimento Medicina Interna, Semeiotica Medica I Padiglione 3, Azienda Ospedaliera Universitaria San Martino, Largo R Benzi 10, 16132 Genoa, Italy
Int Immunopharmacol 7:372-4. 2007..Nasal airflow, as measured by rhinomanometry, is frequently impaired in allergic rhinitis (AR). The decongestion test evaluates whether the application of an intranasal vasoconstrictor drug increases nasal airflow...
Association between response to decongestion testing and sensitizations and allergic inflammationGiorgio Ciprandi
Dipartimento Patologie Testa Collo, Padiglione Specialità piano terzo, Azienda Ospedale Università San Martino, Genoa, Italy
Ann Allergy Asthma Immunol 96:431-6. 2006..Rhinomanometry is used to measure nasal airflow, which is frequently impaired in allergic rhinitis (AR). Decongestion testing consists of spraying an intranasal vasoconstrictor drug to evaluate recovery of nasal airflow...
Safe administration of an inactivated virosomal adjuvanted influenza vaccine in asthmatic children with egg allergySusanna Esposito
Institute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122 Milan, Italy
Vaccine 26:4664-8. 2008..The results showed the safety of the administration, and demonstrated that Inflexal V can be safely given without performing a vaccine skin test in children with any kind of egg allergy...
