G M Liuzzi

Summary

Affiliation: University of Bari
Country: Italy

Publications

  1. ncbi Regulation of gelatinases in microglia and astrocyte cell cultures by plant lectins
    G M Liuzzi
    Dipartimento di Biochimica e Biologia Molecolare, University of Bari, Italy
    Glia 27:53-61. 1999
  2. ncbi Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, 70126 Bari, Italy
    Mult Scler 10:290-7. 2004
  3. ncbi Anti-HIV drugs decrease the expression of matrix metalloproteinases in astrocytes and microglia
    G M Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Via Orabona 4, 70126 Bari, Italy
    Brain 127:398-407. 2004
  4. ncbi Structure-dependent inhibition of gelatinases by dietary antioxidants in rat astrocytes and sera of multiple sclerosis patients
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, Ernesto Quagliariello, University of Bari, Via Orabona 4, 70126, Bari, Italy
    Neurochem Res 36:518-27. 2011
  5. ncbi Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis
    G M Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Italy
    Mult Scler 8:222-8. 2002
  6. ncbi Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-1b treatment in relapsing-remitting MS
    M Trojano
    Department of Neurological and Psychiatric Sciences, University of Bari, Italy
    Neurology 53:1402-8. 1999
  7. ncbi Adhesion molecules and matrix metalloproteinases in Multiple Sclerosis: effects induced by Interferon-beta
    C Avolio
    Neurology Unit, University of Foggia, Foggia, Italy
    Brain Res Bull 61:357-64. 2003
  8. ncbi Lipoprotein(a) in the cerebrospinal fluid of neurological patients with blood-cerebrospinal fluid barrier dysfunction
    Gabriella Pepe
    Department of Biochemistry and Molecular Biology, University of Bari, Italy
    Clin Chem 52:2043-8. 2006
  9. ncbi Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells--implications for complementary multiple sclerosis treatment
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Bari, Italy
    Neurochem Res 32:2184-93. 2007
  10. ncbi Inhibition of aquaporin-4 expression in astrocytes by RNAi determines alteration in cell morphology, growth, and water transport and induces changes in ischemia-related genes
    Grazia Paola Nicchia
    Department of General and Environmental Physiology and Center of Excellence in Comparative Genomics (CEGBA, University of Bari, I-70126 Bari, Italy
    FASEB J 17:1508-10. 2003

Collaborators

Detail Information

Publications13

  1. ncbi Regulation of gelatinases in microglia and astrocyte cell cultures by plant lectins
    G M Liuzzi
    Dipartimento di Biochimica e Biologia Molecolare, University of Bari, Italy
    Glia 27:53-61. 1999
    ....
  2. ncbi Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, 70126 Bari, Italy
    Mult Scler 10:290-7. 2004
    ..These results demonstrate a modulating effect of IFN-beta on the release of MMPs from CNS cells. This effect represents an additional mechanism by which IFN-beta, may decrease the development of new CNS lesions in the course of MS...
  3. ncbi Anti-HIV drugs decrease the expression of matrix metalloproteinases in astrocytes and microglia
    G M Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Via Orabona 4, 70126 Bari, Italy
    Brain 127:398-407. 2004
    ....
  4. ncbi Structure-dependent inhibition of gelatinases by dietary antioxidants in rat astrocytes and sera of multiple sclerosis patients
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, Ernesto Quagliariello, University of Bari, Via Orabona 4, 70126, Bari, Italy
    Neurochem Res 36:518-27. 2011
    ..Therefore, their combined use may represent a powerful tool for the down-regulation of MMPs in the course of MS...
  5. ncbi Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis
    G M Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Italy
    Mult Scler 8:222-8. 2002
    ....
  6. ncbi Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-1b treatment in relapsing-remitting MS
    M Trojano
    Department of Neurological and Psychiatric Sciences, University of Bari, Italy
    Neurology 53:1402-8. 1999
    ....
  7. ncbi Adhesion molecules and matrix metalloproteinases in Multiple Sclerosis: effects induced by Interferon-beta
    C Avolio
    Neurology Unit, University of Foggia, Foggia, Italy
    Brain Res Bull 61:357-64. 2003
    ..This review will highlight the effects induced by rIFNbeta, both in vitro and in vivo, on cell-bound and soluble forms of AMs and on MMPs...
  8. ncbi Lipoprotein(a) in the cerebrospinal fluid of neurological patients with blood-cerebrospinal fluid barrier dysfunction
    Gabriella Pepe
    Department of Biochemistry and Molecular Biology, University of Bari, Italy
    Clin Chem 52:2043-8. 2006
    ....
  9. ncbi Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells--implications for complementary multiple sclerosis treatment
    Grazia Maria Liuzzi
    Department of Biochemistry and Molecular Biology, University of Bari, Bari, Italy
    Neurochem Res 32:2184-93. 2007
    ..Our results suggest that a low fat diet supplemented with omega-3 PUFA may become recommended for the well being of MS patients under therapy...
  10. ncbi Inhibition of aquaporin-4 expression in astrocytes by RNAi determines alteration in cell morphology, growth, and water transport and induces changes in ischemia-related genes
    Grazia Paola Nicchia
    Department of General and Environmental Physiology and Center of Excellence in Comparative Genomics (CEGBA, University of Bari, I-70126 Bari, Italy
    FASEB J 17:1508-10. 2003
    ....
  11. ncbi The different forms of PNS myelin P0 protein within and outside lipid rafts
    Anna Fasano
    Dipartimento di Biochimica e Biologia Molecolare Ernesto Quagliariello, University of Bari, Bari, Italy
    J Neurochem 107:291-301. 2008
    ..Our findings suggest that structural differences between the two proteins, mainly related to the glycogroups, might be responsible for their different localization...
  12. ncbi A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains
    Erik Martens
    Rega Institute for Medical Research, Laboratory of Immunobiology, University of Leuven, Minderbroedersstraat 10, B 3000 Leuven, Belgium
    Biochim Biophys Acta 1770:178-86. 2007
    ..These results define part of the catalytic domain of gelatinase B/MMP-9, and not the zinc-binding or fibronectin domains, as target for the development of selective inhibitors...
  13. ncbi Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes
    Carlo Avolio
    Neurology Unit, University of Foggia, Italy
    J Neuroimmunol 136:46-53. 2003
    ..These results show that an increase in MMP-2/TIMP-2 ratio marks chronic progression in MS, but it is as high as in HC, and also confirm that high MMP-9 activity characterizes short duration relapsing and active forms of the disease...