Research Topics
| Andrea CiprianiSummaryAffiliation: University of Verona Country: Italy Publications
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Publications
What is a run-in phase?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Epidemiol Psichiatr Soc 19:21-2. 2010..In this paper we analysed the implications of run-in periods for interpreting the results of clinical trials and applying these results in clinical practice. Study reports should indicate in details how run-in periods were carried out...- Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysisAndrea Cipriani
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Lancet 378:1306-15. 2011..We did a multiple-treatments meta-analysis, which accounted for both direct and indirect comparisons, to assess the effects of all antimanic drugs... - What is a Cochrane review?A Cipriani
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psychiatr Sci 20:231-3. 2011..In this issue, we highlight the most important methodological features of Cochrane reviews, also reporting details on the editorial process to publish the review in the Cochrane Library... - What is a forest plot?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10-37134 Verona, Italy
Epidemiol Psichiatr Soc 15:258-9. 2006 - Does randomized evidence support sertraline as first-line antidepressant for adults with acute major depression? A systematic review and meta-analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro, 10, 37134 Verona, Italy
J Clin Psychiatry 69:1732-42. 2008..The aim of this study was to carry out a systematic review and meta-analysis to compare sertraline with any other antidepressant in the acute phase treatment of major depression at 8 weeks... - What is a risk ratio?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10, 37134 Verona, Italy
Epidemiol Psichiatr Soc 16:20-1. 2007 - Metareview on short-term effectiveness and safety of antidepressants for depression: an evidence-based approach to inform clinical practiceAndrea Cipriani
Department of Medicine and Public Health, University of Verona, Italy
Can J Psychiatry 52:553-62. 2007.... - Allocation concealment and blinding in clinical trialsAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 17:115-6. 2008 - What is a clinical trial protocol?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Epidemiol Psichiatr Soc 19:116-7. 2010..Trial protocols must meet a standard that adheres to the principles of Good Clinical Practice, and are used to obtain ethics approval by local Ethics Committees or Institutional Review Boards... - Olanzapine in the long-term treatment of bipolar disorder: a systematic review and meta-analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L A Scuro 10, Verona, Italy
J Psychopharmacol 24:1729-38. 2010..We conclude that olanzapine may prevent further manic episodes only in patients who have responded to olanzapine in an acute manic or mixed episode and who have not previously had a satisfactory response to lithium or valproate... - What is an individual patient data meta-analysis?Andrea Cipriani
Epidemiol Psichiatr Soc 16:203-4. 2007 - Superiority, equivalence or non-inferiority?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 18:311-3. 2009..Three kinds of RCTs may be designed: Superiority trials, Equivalence studies, Non-inferiority studies... - What is an intention to treat analysis?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 17:26-7. 2008 - Aripiprazole versus haloperidol in combination with clozapine for treatment-resistant schizophrenia in routine clinical care: a randomized, controlled trialCorrado Barbui
World Health Organization Collaborating Centre for Research and Training in Mental Health and Service Organization, Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, Verona, Italy
J Clin Psychopharmacol 31:266-73. 2011..However, an advantage in the perception of adverse effects with aripiprazole treatment may be meaningful for patients... - Sertraline versus other antidepressive agents for depressionAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro, 10, Verona, Italy, 37134
Cochrane Database Syst Rev 4:CD006117. 2010..However, the included studies did not report on all the outcomes that were pre-specified in the protocol of this review. Outcomes of clear relevance to patients and clinicians were not reported in any of the included studies... - Understanding antipsychotic non-classical prescriptions: a quantitative and qualitative approachAntonio Veronese
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L A Scuro 10, 37134 Verona, Italy
Epidemiol Psichiatr Soc 17:236-41. 2008..The present study was carried out to develop concepts which help understand this phenomenon in a natural setting, giving emphasis to views of clinicians according to quali - quantitative research methodologies... - Are all antidepressants really the same? The case of fluoxetine: a systematic reviewAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
J Clin Psychiatry 67:850-64. 2006..To systematically review the efficacy and tolerability of fluoxetine, the most widely studied of newer antidepressants, in comparison with all other antidepressants in the acute treatment of depression in patients aged more than 18 years... - Antidepressant drug prescription and risk of abnormal bleeding: a case-control studyCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, WHO Collaborating Centre for Research and Training in Mental Health, University of Verona, Italy
J Clin Psychopharmacol 29:33-8. 2009..74; 95% CI, 1.04-2.93). In a population with a low baseline risk of bleeding, we detected a significant increase in the risk of gastrointestinal bleeding only... - Relationship between quality of reports of antidepressant randomized controlled trials and treatment estimates: systematic review, meta-analysis, and meta-regression analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
J Clin Psychopharmacol 27:352-6. 2007..However, current quality measures are not related with treatment estimates in antidepressant trials and may not be useful weighting tools when meta-analyses of data extracted from antidepressant RCTs are carried out... - Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy Department of Psychiatry, University of Oxford, UK
Lancet 373:746-58. 2009..We therefore did a multiple-treatments meta-analysis, which accounts for both direct and indirect comparisons, to assess the effects of 12 new-generation antidepressants on major depression... - Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studiesCorrado Barbui
World Health Organization Collaborating Centre for Research and Training in Mental Health, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
CMAJ 180:291-7. 2009..We explored the association between exposure to SSRIs and risk of suicide completion or attempt... - Benzodiazepine use in the real world of psychiatric practice: low-dose, long-term drug taking and low rates of treatment discontinuationAntonio Veronese
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Ospedale Policlinico, 37134, Verona, Italy
Eur J Clin Pharmacol 63:867-73. 2007.... - Rationale and design of an independent randomised controlled trial evaluating the effectiveness of aripiprazole or haloperidol in combination with clozapine for treatment-resistant schizophreniaMichela Nose
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Trials 10:31. 2009.... - Seven criteria for improving effectiveness trials in psychiatryMichele Tansella
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Psychol Med 36:711-20. 2006..There are no published criteria for improving the quality of effectiveness of randomized controlled trials (RCTs) in psychiatry... - Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysisCorrado Barbui
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, 37134 Verona, Italy
Br J Psychiatry 198:11-6, sup 1. 2011..Depression is a common condition that has been frequently treated with psychotropics... - Validity of the impact factor of journals as a measure of randomized controlled trial qualityCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
J Clin Psychiatry 67:37-40. 2006..To assess whether the impact factor, a measure of the frequency with which journal articles are cited in the scientific literature, is a proxy measure of the quality of articles reporting the results of randomized controlled trials... - Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trialsCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, World Health Organization Collaborating Centre for Research and Training in Mental Health, University of Verona, Verona, Italy
CMAJ 178:296-305. 2008..We undertook a systematic review of published and unpublished clinical trial data to determine the effectiveness and acceptability of paroxetine... - Does the addition of a second antipsychotic drug improve clozapine treatment?Corrado Barbui
Schizophr Bull 35:458-68. 2009..91, 95% CI = 0.75 to 1.11). We conclude that the evidence base supporting a second antipsychotic in addition to clozapine in partially responsive patients with schizophrenia is weak. This weak evidence indicates modest to absent benefit... - Antidepressants and suicide symptoms: compelling new insights from the FDA's analysis of individual patient level dataCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Evid Based Ment Health 11:34-5. 2008 - Impact of regulatory changes on first- and second-generation antipsychotic drug consumption and expenditure in ItalyMargherita Andretta
Servizio Farmaceutico, ULSS 20, Verona, Italy
Soc Psychiatry Psychiatr Epidemiol 40:72-7. 2005.... - Assessing risk of bias in randomized controlled trialsMarianna Purgato
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Epidemiol Psichiatr Soc 19:296-7. 2010.... - Randomized trials published in chinese or Western journals: comparative empirical analysisMarianna Purgato
From the Section of Psychiatry, Department of Public Health and Community Medicine, University of Verona, Verona, Italy
J Clin Psychopharmacol 32:354-61. 2012..The increasing inclusion of Chinese studies in systematic reviews reinforces the need to check the quality of randomized trials that are meta-analyzed... - Antipsychotic drugs and cerebrovascular events in elderly patients with dementia: a systematic reviewSara Mazzucco
Department of Neurological Sciences and Vision, Section of Clinical Neurology, University of Verona, Piazzale L A Scuro, 10, 37134 Verona, Italy
Mini Rev Med Chem 8:776-83. 2008..Assessing both randomised and non-randomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice... - "Wish bias" in antidepressant drug trials?Corrado Barbui
Section of Psychiatry, Department of Medicine and Public Health, University of Verona, Verona, Italy
J Clin Psychopharmacol 24:126-30. 2004..The evidence that the outcome of fluoxetine trials varied according to whether this drug was used as a new compound or a reference one suggests the presence of bias... - CNS drugs approved by the centralised European procedure: true innovation or dangerous stagnation?Corrado Barbui
Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, Piazzale Scuro 10, 37134, Verona, Italy
Psychopharmacology (Berl) 190:265-8. 2007 - Explanatory and pragmatic trialsCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10 - 37134 Verona, Italy
Epidemiol Psichiatr Soc 16:124-5. 2007 - What is a systematic review?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Epidemiol Psichiatr Soc 15:174-5. 2006 - Publication bias in systematic reviewsCorrado Barbui
Arch Gen Psychiatry 64:868. 2007 - International dosage differences in fluoxetine clinical trialsScott Patten
Department of Community Health Sciences, University of Calgary, Alberta
Can J Psychiatry 50:31-8. 2005..CONCLUSIONS: International differences in prescriber behaviour may influence, and in turn be influenced by, the conduct of clinical trials. It is difficult to reconcile such differences with the principles of evidence-based medicine... - Imputing missing standard deviations in meta-analyses can provide accurate resultsToshi A Furukawa
Department of Psychiatry and Cognitive Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho cho, Mizuho ku, Nagoya 467 8601 Japan
J Clin Epidemiol 59:7-10. 2006..Some meta-analysts substitute them by those reported in other studies, either from another meta-analysis or from other studies in the same meta-analysis. But the validity of such practices has never been empirically examined... - Lithium in the prevention of suicidal behavior and all-cause mortality in patients with mood disorders: a systematic review of randomized trialsAndrea Cipriani
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK
Am J Psychiatry 162:1805-19. 2005.... - Long-term treatment of depression with antidepressants: a systematic narrative reviewToshi A Furukawa
Department of Psychiatry and Cognitive Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Japan
Can J Psychiatry 52:545-52. 2007..To examine the available scientific evidence for answers to clinically relevant questions on the effectiveness and tolerability of antidepressant drugs (ADs) for the long-term treatment of depression... - Selective serotonin reuptake inhibitorsJohn R Geddes
BMJ 329:809-10. 2004 - Imputing response rates from means and standard deviations in meta-analysesToshi A Furukawa
Department of Psychiatry, Nagoya City University Medical School, Mizuho cho, Mizuho ku, Nagoya, Japan
Int Clin Psychopharmacol 20:49-52. 2005..This would allow a more robust and clinically interpretable estimation of the true, underlying treatment effect to be made... - Depressive disorder needs an evidence base commensurate with its public health importanceJohn R Geddes
Can J Psychiatry 52:543-4. 2007 - Venlafaxine for major depressionAndrea Cipriani
BMJ 334:215-6. 2007 - Suicide, depression, and antidepressantsAndrea Cipriani
BMJ 330:373-4. 2005 - Efficacy and tolerability of milnacipran in the treatment of major depression in comparison with other antidepressants : a systematic review and meta-analysisAtsuo Nakagawa
Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan
CNS Drugs 22:587-602. 2008..We undertook a systematic review and meta-analysis of randomized controlled trials that compared the efficacy and tolerability of milnacipran with other antidepressants... - Depressive disordersRob Butler
University of Auckland and Waitemata Health, New Zealand
Am Fam Physician 73:1999-2004. 2006