Research Topics
| R CaporaliSummaryAffiliation: University of Pavia Country: Italy Publications
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Publications
Inflammatory myopathy in a patient with cutaneous findings of pityriasis rubra pilaris: a case of Wong's dermatomyositisRoberto Caporali
Department of Rheumatology, IRCCS Policlinico, San Matteo Hospital, University of Pavia, Piazzale Golgi 2, 27100, Pavia, Italy
Clin Rheumatol 23:63-5. 2004..Treatment with prednisone and hydroxychloroquine led to complete control of the cutaneous and muscular involvement, which was maintained during prednisone tapering...- Comorbid conditions in the AMICA study patients: effects on the quality of life and drug prescriptions by general practitioners and specialistsRoberto Caporali
Rheumatology, University of Pavia, IRCCS Policlinico S Matteo, Pavia, Italy
Semin Arthritis Rheum 35:31-7. 2005..The AMICA study evaluated how the presence of a coexistent disease and/or its chronic pharmacological treatment influenced the prescription of pharmacological and nonpharmacological therapy in patients with OA... - Safety and usefulness of minor salivary gland biopsy: retrospective analysis of 502 procedures performed at a single centerRoberto Caporali
Department of Rheumatology, University of Pavia, IRCCS San Matteo Foundation, Pavia, Italy
Arthritis Rheum 59:714-20. 2008..To analyze the safety of our biopsy technique and the effectiveness of minor salivary gland biopsy (MSGB) for the diagnosis of Sjögren's syndrome (SS) and amyloidosis... - Presenting features of polymyalgia rheumatica (PMR) and rheumatoid arthritis with PMR-like onset: a prospective studyR Caporali
Cattedra di Reumatologia, Universita di Pavia, Pavia, Italy
Ann Rheum Dis 60:1021-4. 2001..To evaluate in a prospective study whether patients with polymyalgia rheumatica (PMR) and patients with rheumatoid arthritis (RA) with PMR-like onset show distinctive clinical and laboratory features... - Do physicians treat symptomatic osteoarthritis patients properly? Results of the AMICA experiencePiercarlo Sarzi-Puttini
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Semin Arthritis Rheum 35:38-42. 2005..The study was designed to evaluate their prescription modalities to determine whether they matched the recently proposed treatment guidelines for OA (ACR 2000; EULAR 2000; APS 2002)... - The correct prednisone starting dose in polymyalgia rheumatica is related to body weight but not to disease severityMarco A Cimmino
Clinica Reumatologica, Dipartimento di Medicina Interna, Universita di Genova, Viale Benedetto XV, 6, 16132 Genova, Italy
BMC Musculoskelet Disord 12:94. 2011..The aim of this study is to test if 12.5 mg prednisone/day is an adequate starting dose in PMR and to evaluate clinical predictors of drug response... - Multilevel examination of minor salivary gland biopsy for Sjogren's syndrome significantly improves diagnostic performance of AECG classification criteriaPatrizia Morbini
Department of Pathology, IRCCS Policlinico S Matteo, Pavia, Italy
Arthritis Res Ther 7:R343-8. 2005..The assessment of a cFS obtained at three different section levels on minor salivary gland biopsies can be useful especially in biopsies with baseline FSs between 1 and 2... - Immunohistological assessment of the synovial tissue in small joints in rheumatoid arthritis: validation of a minimally invasive ultrasound-guided synovial biopsy procedureCarlo Alberto Scirè
Chair and Division of Rheumatology, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Piazzale Golgi 12, I 27100 Pavia, Italy
Arthritis Res Ther 9:R101. 2007..In conclusion, US-guided synovial biopsy represents a reliable tool for the assessment of the histopathological features of RA patients with a mini-invasive approach... - Autoantibody profile in rheumatoid arthritis during long-term infliximab treatmentFrancesca Bobbio-Pallavicini
Department of Rheumatology University of Pavia, IRCCS Policlinico S, Matteo, Pavia, Italy
Arthritis Res Ther 6:R264-72. 2004..Also, the evolution of RF titres and that of anti-CCP antibody titres differed during long-term infliximab therapy... - Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitisFabiola Atzeni
Rheumatology Unit, L, Sacco Hospital, University of Milan, Via G, B, Grassi 74, 20127 Milan, Italy
Arthritis Res Ther 10:R51. 2008..The purpose of this study was to investigate the prevalence of cyclic citrullinated peptide antibodies (anti-CCP) in patients with primary Sjögren syndrome (pSS) and its correlation with clinical and laboratory data... - Cardiovascular effects of coxibsR Caporali
University of Pavia, IRCCS Policlinico S Matteo, Pavia, Italy
Lupus 14:785-8. 2005..Long-term studies with a cardiovascular endpoint involving both selective and nonselective anti-inflammatory drugs are warranted... - Glucocorticoid treatment of polymyalgia rheumaticaR Caporali
Division of Rheumatology, University of Pavia, IRCCS S Matteo Foundation, Pavia, Italy
Clin Exp Rheumatol 29:S143-7. 2011..The role of glucocorticoids in the pathogenesis of PMR, as well as the available evidence concerning different schedules of glucocorticoid treatment, including administration according to circadian rhythms, are discussed... - DMARDS and infections in rheumatoid arthritisRoberto Caporali
Rheumatology, University of Pavia, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
Autoimmun Rev 8:139-43. 2008..Beside the general positive profile of DMARDs as for infectious risk, a careful use and tight control of the patients is recommended... - Treatment of rheumatoid arthritis with anti-TNF-alpha agents: a reappraisalRoberto Caporali
Rheumatology Unit, University of Pavia, IRCCS Policlinico S Matteo Foundation, 27100 Pavia, Italy
Autoimmun Rev 8:274-80. 2009..As the first published registry of anti-TNFalpha-treated patients in Italy, Lombardy Rheumatology Network (LORHEN) is already making its contribution in this direction... - Long term treatment of rheumatoid arthritis with rituximabRoberto Caporali
Rheumatology Dept, IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
Autoimmun Rev 8:591-4. 2009..The use of rituximab in clinical practice has highlighted its efficacy and safety over more than 5 years of treatment, as well as to try to understand the timing for retreatment of patients relapsing after a good initial response... - Switching TNF-alpha antagonists in rheumatoid arthritis: the experience of the LORHEN registryRoberto Caporali
Division of Rheumatology, University of Pavia, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
Autoimmun Rev 9:465-9. 2010..The patients with higher disease activity levels and those stopping the first anti-TNFalpha treatment because of a lack of efficacy are very likely to respond to the second treatment... - Safety of tumor necrosis factor alpha blockers in hepatitis B virus occult carriers (hepatitis B surface antigen negative/anti-hepatitis B core antigen positive) with rheumatic diseasesR Caporali
University of Pavia, IRCCS S Matteo Foundation, Pavia, Italy
Arthritis Care Res (Hoboken) 62:749-54. 2010.... - Recommendations for the use of biologic therapy in rheumatoid arthritis: update from the Italian Society for Rheumatology I. EfficacyRoberto Caporali
Division of di Rheumatology, University of Pavia, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
Clin Exp Rheumatol 29:S7-14. 2011..The recommendations reported are intended to help prescribing rheumatologists to optimise the use of biologic agents in patients with RA seen in everyday practice; they are not to be considered as a regulatory rule... - Rheumatoid arthritis in beta-thalassemic trait: clinical, serologic and immunogenetic profileRoberto Caporali
Cattedra e Unità Operativa di Reumatologia, Università di Pavia IRCCS Policlinico S Matteo, 27100 Pavia, Italy
Joint Bone Spine 71:117-20. 2004..To investigate the clinical, serologic, radiologic and immunogenetic characteristics of rheumatoid arthritis (RA) occurring in patients with beta-thalassemic trait as compared with RA in control patients from the same geographical area... - Prednisone plus methotrexate for polymyalgia rheumatica: a randomized, double-blind, placebo-controlled trialRoberto Caporali
University of Pavia, Pavia, Italy
Ann Intern Med 141:493-500. 2004..Steroids are the standard treatment for polymyalgia rheumatica. The efficacy of the candidate drug methotrexate has not yet been demonstrated in controlled studies... - Efficacy and safety of anti-TNF agents in the Lombardy rheumatoid arthritis network (LORHEN)P Sarzi-Puttini
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Reumatismo 60:290-5. 2008.... - Infliximab in the treatment of adult Still's disease refractory to conventional therapyL Cavagna
Chair of Rheumatology, University of Pavia, Policlinico San Matteo, Piazzale Golgi no. 2, 27100 Pavia, Italy
Clin Exp Rheumatol 19:329-32. 2001..Further studies are needed to evaluate the long-term safety, efficacy and the optimal schedule of infusion... - Autoantibodies to RNA-polymerases in Italian patients with systemic sclerosisA Bardoni
Department of Biochemistry A. Castellani, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
Clin Exp Rheumatol 21:301-6. 2003..CONCLUSIONS: Anti-RNA-polymerase antibodies appear to be less frequent in Italian patients than in Caucasian patients from the United Kingdom or USA. This might be associated with the lower frequency of scleroderma renal crisis... - Clinical presentation of osteoarthritis in general practice: determinants of pain in Italian patients in the AMICA studyMarco A Cimmino
Rheumatology, University of Genoa, Genoa, Italy
Semin Arthritis Rheum 35:17-23. 2005..To assess the clinical characteristics and determinants of pain observed by general practitioners (GPs) in Italian patients with osteoarthritis (OA) of the hand, hip, and knee... - Impaired bone marrow hematopoietic progenitor cell function in rheumatoid arthritis patients candidated to autologous hematopoietic stem cell transplantationC Porta
Istituto di Medicina Interna ed Oncologia Medica, Università degli Studi di Pavia e I R C C S Policlinico San Matteo, Pavia, Italy
Bone Marrow Transplant 33:721-8. 2004..These observations may identify the biological risk factors for impaired mobilization and/or engraftment when RA patients are candidates for autologous hematopoietic stem cell grafting... - High IgA rheumatoid factor levels are associated with poor clinical response to tumour necrosis factor alpha inhibitors in rheumatoid arthritisFrancesca Bobbio Pallavicini
Cattedra di Reumatologia, Policlinico S Matteo, 27100 Pavia, Italy
Ann Rheum Dis 66:302-7. 2007.... - Predicting response to anti-TNF treatment in rheumatoid arthritis patientsFabiola Atzeni
Rheumatology Unit, L Sacco University Hospital, Milan, Italy
Autoimmun Rev 8:431-7. 2009..To identify the clinical factors predicting failure or a good clinical response in the cohort of RA patients entered in the Lombardy Rheumatology Network (LORHEN) registry after 3 years of treatment with anti-TNF agents... - Analysis of pharmacologic and nonpharmacologic prescription patterns of general practitioners and specialists in the AMICA studyRaffaele Scarpa
Rheumatology, Federico II University, Naples, Italy
Semin Arthritis Rheum 35:24-30. 2005..To evaluate the prescription modalities of general practitioners (GPs) and specialists in symptomatic osteoarthritis (OA) patients enrolled in the AMICA study... - Prevalence of undiagnosed autoimmune rheumatic diseases in the first trimester of pregnancy. Results of a two-steps strategy using a self-administered questionnaire and autoantibody testingA Spinillo
Department of Obstetrics and Gynecology, IRCCS Fondazione Policlinico San Matteo, University of Pavia, Pavia, Italy
BJOG 115:51-7. 2008..To evaluate the prevalence of undiagnosed rheumatic diseases in the first trimester of pregnancy... - Role of chemokines and chemokine receptors in regulating specific leukocyte trafficking in the immune/inflammatory responseA Manzo
Cattedra di Reumatologia, Universita' degli Studi di Pavia, IRCCS Policlinico S. Matteo, 27100 Pavia, Italy
Clin Exp Rheumatol 21:501-8. 2003..In this review we discuss the role of chemokines and chemokine receptors in regulating leukocyte trafficking in different anatomical sites in the context of distinct functional phases of the immune/inflammatory response... - [Plasma procalcitonin in rheumatic diseases]C A Scirè
Cattedra e Unità Operativa di Reumatologia, Pavia, Italy
Reumatismo 55:113-8. 2003..This review will focus on the clinical significance of changes in serum procalcitonin levels in patients with connective tissue diseases and other rheumatic disorders... - The effect of newly diagnosed undifferentiated connective tissue disease on pregnancy outcomeArsenio Spinillo
Department of Obstetrics and Gynecology, IRCCS Fondazione Policlinico San Matteo, University of Pavia, Pavia, Italy
Am J Obstet Gynecol 199:632.e1-6. 2008..The purpose of this study was to evaluate pregnancy outcome in a cohort of patients with newly diagnosed undifferentiated connective tissue disease (UCTD)... - B cells in rheumatoid arthritisSerena Bugatti
Chair and Division of Rheumatology, University of Pavia, IRCCS Fondazione Policlinico San Matteo, Piazzale Golgi 2, 27100 Pavia, Italy
Autoimmun Rev 7:137-42. 2007..All of these functions are essential in the development of RA, and lately have claimed attention as B cell depletion has become a common and effective strategy of treatment in RA... - Autoimmunity in thrombotic thrombocytopenic purpuraCamillo Porta
A Ferrata Institute of Internal Medicine and Medical Oncology, I R C C S San Matteo University Hospital, Pavia, Italy
Semin Thromb Hemost 31:633-40. 2005.... - Analysis of the apolipoprotein(a) size polymorphism in patients with systemic lupus erythematosusEmmanouil Peros
Department of Internal Medicine and Medical Therapeutics, Section of Internal Medicine, Vascular and Metabolic Diseases, IRCCS San Matteo Hospital, University of Pavia, 27100 Pavia, Italy
Int J Mol Med 15:661-5. 2005..As small apo(a) phenotypes have been related to adverse vascular effects, it is feasible that small apo(a) isoforms may be a useful biological marker in the assessment of vascular risk in patients with SLE... - Early disease control by low-dose prednisone comedication may affect the quality of remission in patients with early rheumatoid arthritisMonica Todoerti
Division of Rheumatology, University of Pavia, IRCCS S Matteo Foundation, Piazzale Golgi, Pavia, Italy
Ann N Y Acad Sci 1193:139-45. 2010..480, CI 95% 1.354-14.817, P= 0.014). In conclusion, we found as in early RA low-dose prednisone comedication is associated with higher rate of clinical remission, earlier disease activity control and more stable remission over time... - Proliferation characteristics and polyploidization of cultured myofibroblasts from a patient with fibroblastic rheumatismC Lanni
Dipartimento di Biologia Animale and Istituto di Genetica Molecolare del CNR (Sezione di Istochimica e Citometria, University of Pavia, Italy
Eur J Histochem 47:257-62. 2003.... - Anti-tumor necrosis factor-alpha response in rheumatoid arthritis is associated with an increase in serum soluble CD30Roberto Gerli
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Rheumatol 35:14-9. 2008..To verify the contribution of this T cell subset to disease remission, sCD30 levels were analyzed longitudinally in patients with active RA following infliximab therapy... - Tumour necrosis factor antagonist therapy and cancer development: analysis of the LORHEN registryFrancesca Bobbio Pallavicini
Rheumatology Department, IRCCS Policlinico S Matteo, University of Pavia, Pavia, Italy
Autoimmun Rev 9:175-80. 2010..The objective was to compare cancer risk in a RA cohort population treated with TNF antagonists, and identify the characteristics of the patients at higher risk... - Direct and indirect costs of osteoarthritis of the kneeG Leardini
Division of Rheumatology, Venice, Italy
Clin Exp Rheumatol 22:699-706. 2004..5% of GDP in industrialized countries and osteoarthritis is the most common joint disorder. Osteoarthritis of the knee is especially common and is a major cause of disability requiring extensive utilization of health care resources... - Osteoarthritis: an overview of the disease and its treatment strategiesPiercarlo Sarzi-Puttini
Division of Rheumatology, L Sacco University Hospital, Milan, Italy
Semin Arthritis Rheum 35:1-10. 2005..The disease course and patient's requirements often change over time, thus requiring a periodic review and readjustment of therapy rather than the rigid continuation of a single treatment... - Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: power Doppler signal predicts short-term relapseCarlo A Scirè
Division of Rheumatology, Early Arthritis Clinic, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
Rheumatology (Oxford) 48:1092-7. 2009..This study aimed to evaluate the usefulness of a systematic musculoskeletal ultrasonographic (US) assessment in the detection of residual disease activity in patients with early RA who achieved clinical remission... - Efficacy of tidal irrigation in Milwaukee shoulder syndromeOscar Epis
Department of Rheumatology, University of Pavia, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
J Rheumatol 34:1545-50. 2007..To assess the efficacy of tidal irrigation in patients with Milwaukee shoulder syndrome (MSS)... - Predictive value of antibodies to citrullinated peptides and rheumatoid factors in anti-TNF-alpha treated patientsFrancesca Bobbio-Pallavicini
Division of Rheumatology, University of Pavia, IRCCS Policlinico S Matteo Foundation, Pavia, Italy
Ann N Y Acad Sci 1109:287-95. 2007..Pre-treatment RF positivity or negativity does not influence response to TNF-alpha blocking therapy while high pre-treatment levels of IgA RF seem to be associated with a poor response rate... - B cells in rheumatoid arthritisSerena Bugatti
Chair and Division of Rheumatology, University of Pavia, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy
Autoimmun Rev 6:482-7. 2007..All of these functions are essential in the development of RA, and lately have claimed attention as B cell depletion has become a common and effective strategy of treatment in RA... - -238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic SclerosisBarbara Tolusso
Division of Rheumatology, UCSC Catholic University of Rome, Rome, Italy
Immunol Lett 96:103-8. 2005..To investigate possible associations of TNF-alpha and TNF-RII gene polymorphisms with diffuse or limited skin involvement phenotype in a cohort of Systemic Sclerosis (SSc) patients... - Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulinsValentina Navazza
Department of Internal Medicine, Clinica Medica I, Fondazione IRCCS Policlinico San Matteo University of Pavia, P le Golgi 2, 27100 Pavia, Italy
Mol Immunol 45:1519-24. 2008..In particular, a rare replacement of a polar residue with proline is shared at the beginning of the VH complementarity-determining region 2, and this residue might be involved in intermolecular contacts... - Antibodies to cyclic citrullinated peptides in psoriatic arthritisLaura Bogliolo
Department of Rheumatology and the Clinical Chemistry Laboratories, University of Pavia, IRCCS Policlinico S. Matteo, Pavia, Italy
J Rheumatol 32:511-5. 2005..99; 3.6-89.2). CONCLUSION: Anti-CCP can be found in a small but significant proportion of patients with a clinical picture of PsA and are associated with erosive arthritis and multiple joint involvement... - Involvement of subchondral bone marrow in rheumatoid arthritis: lymphoid neogenesis and in situ relationship to subchondral bone marrow osteoclast recruitmentSerena Bugatti
University of Pavia, IRCCS Policlinico S. Matteo, Piazzale Golgi 2, 27100 Pavia, Italy
Arthritis Rheum 52:3448-59. 2005..Moreover, the local inflammation/aggregation process appears to be related to osteoclast differentiation on the marrow side of subchondral bone, supporting a functional role of the bone compartment in local damage... - The characteristics of symptomatic osteoarthritis in general and specialist practice in Italy: design and methods of the AMICA StudyFabio Parazzini
Division of Epidemiology, Istituto Mario Negri, Milan, Italy
Semin Arthritis Rheum 35:11-6. 2005..The diagnostic and clinical approach to osteoarthritis (OA) of the hand, knee, and hip in general practice and specialist practice in Italy as determined by the AMICA project... - Prescribing pattern of drugs in the treatment of osteoarthritis in Italian general practice: the effect of rofecoxib withdrawalMarianna Alacqua
University of Messina, Messina, Italy
Arthritis Rheum 59:568-74. 2008..The aim of the present study was to compare the trend of nonsteroidal antiinflammatory drug (NSAID) use and other analgesics in osteoarthritis (OA) treatment before and after rofecoxib withdrawal in Italian general practice... - Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitisAntonio Manzo
Rheumatology Unit, Guy's, King's and St Thomas' School of Medicine, Guy's Campus, London, UK
Eur J Immunol 35:1347-59. 2005.... - Glucocorticoid effects on adrenal steroids and cytokine responsiveness in polymyalgia rheumatica and elderly onset rheumatoid arthritisAlberto Sulli
Research Laboratory and Division of Rheumatology, Department of Internal Medicine, San Martino Hospital, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy
Ann N Y Acad Sci 1069:307-14. 2006..Interestingly, in PMR and EORA/PMR patients, GC treatment was found to downregulate PRG serum levels... - Clinical and electrophysiological evaluation of peripheral neuropathy in rheumatoid arthritisGiovanni Albani
J Peripher Nerv Syst 11:174-5. 2006 - CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesisAntonio Manzo
Rheumatology Unit, Guy s, King s, and St Thomas School of Medicine, London, United Kingdom
Am J Pathol 171:1549-62. 2007.... - Is the course of steroid-treated polymyalgia rheumatica more severe in women?Marco A Cimmino
Clinica Reumatologica, Dipartimento di Medicina Interna e Specialita Mediche, Universita di Genova, Viale Benedetto XV, 6, 16129 Genova, Italy
Ann N Y Acad Sci 1069:315-21. 2006..In conclusion, sex is probably modulating the response to corticosteroids. This finding emphasizes the need to consider differences between males and females in the clinical and therapeutic approach to PMR patients...